• Title/Summary/Keyword: Treatment Efficacy

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The antioxidant activities of Korean Red Ginseng (Panax ginseng) and ginsenosides: A systemic review through in vivo and clinical trials

  • Park, Soo Kyung;Hyun, Sun Hee;In, Gyo;Park, Chae-Kyu;Kwak, Yi-Seong;Jang, Young-Jin;Kim, Bumseok;Kim, Jong-Hoon;Han, Chang-Kyun
    • Journal of Ginseng Research
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    • v.45 no.1
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    • pp.41-47
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    • 2021
  • A wide range of studies have steadily pointed out the relation of oxidative stress to the primary and secondary causes of human disease and aging. As such, there have been multiple misconceptions about oxidative stress. Most of reactive oxygen species (ROS) generated from chronic diseases cause oxidative damage to cell membrane lipids and proteins. ROS production is increased by abnormal stimulation inside and outside in the body, and even though ROS are generated in cells in response to abnormal metabolic processes such as disease, it does not mean that they directly contribute to the pathogenesis of a disease. Therefore, the focus of treatment should not be on ROS production itself but on the prevention and treatment of diseases linked to ROS production, including types 1 and 2 diabetes, cancer, heart disease, schizophrenia, Parkinson's disease, and Alzheimer's disease. In this regard, Korean Red Ginseng (KRG) has been traditionally utilized to help prevent and treat diseases such as diabetes, cancer, inflammation, nervous system diseases, cardiovascular disease, and hyperlipidemia. Therefore, this review was intended to summarize in vivo animal and human clinical studies on the antioxidant activities of KRG and its components, ginsenosides.

Effects of Learning Motive Enhancing Program on Academic Self Efficacy, Learning Habits, and Self Esteem in Underachieve Nursing College Students (학습동기향상프로그램이 학습부진 간호대학생의 학업적 자기효능감, 학습습관 및 자아존중감에 미치는 효과)

  • Lee, Sung-Hee
    • The Journal of Korean Academic Society of Nursing Education
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    • v.12 no.1
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    • pp.5-12
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    • 2006
  • Purpose: The purpose of this study was to examine the effects of learning motive enhancing program on academic self efficacy, learning habits, and self esteem in underachieve nursing college students. Method: This study was an one group pre and post test design. Underachievers in nursing college (n=38) were participated. Learning motive enhancing program was carried out for 110 minutes a week for 8 weeks. Academic self efficacy was measured by an academic self efficacy scale developed by Kim ae young & Park in young in 2001. To assess learning habits, the learning habits measurement scale developed by Kim young jin was used. Self esteem was measured by Rosenberg's self esteem scale. Result: After completing the learning motive enhancing program, significant improvement was found in learning habit and self esteem. As for sub-factors, efficacy for self confidence among academic self efficacy showed significant differences after treatment. Conclusion: Learning motive enhancing program appears to be effective in increasing learning habit and self-esteem of underachievers in nursing college students.

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Anthelmintic Efficacy of Albendazole and Ivermectin Against Gastrointestinal Nematodes, Trematodes and Cestode in Korean Native Goats (반추수(反芻獸)의 내부기생충(內部寄生蟲)에 대한 Albendazole과 Ivermectin의 구충효과(驅蟲效果))

  • Suh, Myung-deuk
    • Korean Journal of Veterinary Research
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    • v.26 no.2
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    • pp.321-327
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    • 1986
  • The anthelmintic efficacy of Albendazo1e and Ivermectin against gastrointestinal nematodes, trematodes and cestode was tested in naturally infected Korean native goats. Albendazole was medicated at a dose rate of 10mg/kg of body weight orally and Ivermectin was injected at a dose rate of 0.2mg/kg of body weight subcutaneously. The efficacy was measured by faecal examinations on the day 7th and the day 14th :after treatment. The results obtained were summarized as follows : 1. The efficacy of Albendazole against trematodes and cestode was shown 91.7% in Fasciola hepatica, 68.8% in Paramphislomum spp., 66.7% in Eurytrema pancreaticum and 100% in Moniezia expansa(cestode). 2. The efficacy of Ivermectin against trematodes and cestode was shown 38.8% in Fasciola hepalica, 26.1% in Paramphistomum spp., 22,2% in Eurytrema pancreaticum and 100% in Moniezia expansa(cestode). 3. The anthelmintic efficacy of Albendazole against gastrointestinal nematodes was shown 97.7% in Haemonchus contorus and 100% in Oesophagostomum spp., Ostertagia spp., Bunostomum trigonocephalum, Trichostrongylus spp., Strongyloides papillosus and Cooperia spp. 4. The efficacy of Ivermectin against gastrointestinal nematodes was shown 96.6% in Haemonchus contortus, 94.1% in Trichostrongylus spp. and 100% in Oesophagostomum spp., Ostertagia spp., Bunostomum trigonocephalum, Strongyloides papillosus and Cooperia spp.

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Effects of Self-efficacy Promotion Program for Patients with Epicondylitis (상과염 환자에서 자기효능증진 프로그램의 효과)

  • Kim, Sun Hwa;Kim, Bog Ja
    • Journal of Korean Clinical Nursing Research
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    • v.16 no.2
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    • pp.43-55
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    • 2010
  • Purpose: This study was done to evaluate the effects of program promoting self-efficacy patients with epicondylitis. Methods: Forty-three patients with unilateral epicondylitis were enrolled in this study between January, 2 and April, 28, 2009. The patients were assigned to one of two groups: Nineteen patients in the intervention group were given the self-efficacy promotion program with specific home instruction and the 24 in the control group were treated with conventional treatment. Pain by numeric rating scale, anxiety, and the self-efficacy of exercise were evaluated before the program, and 4 weeks after completing the intervention. The number of exercises was checked after the intervention. The data were analyzed using descriptive statistics, t-test, Chi-square test, paired t-test, Pearson's correlation coefficients with SPSS 14.0 program. Results: Anxiety in the intervention group was significantly lower than the control group(p=.018). Maximal and resting pain in the control group were lower than the intervention group( p=.000, p=.003). The self-efficacy of exercise and the number of exercises increased in the intervention group but there was no significant difference (p=.057, p=.052). Conclusion: The results of this study indicate that a program promoting self-efficacy for patients with epicondylitis could be a useful nursing intervention to reduce anxiety.

An Effect of a Self-Efficacy Information Resources Program on Perceived Self-Efficacy and Self-Care in Patients with Coronary Artery Disease (자기효능 정보자원 프로그램이 관상동맥 질환 환자의 지각된 자기효능감과 자가간호행위에 미치는 효과)

  • Shin, Ju-Young;Khim, Soon-Yong
    • Korean Journal of Adult Nursing
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    • v.14 no.1
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    • pp.114-124
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    • 2002
  • Purpose: This study was conducted to investigate whether a self-efficacy information resources program based on the self-efficacy theory of Bandura (1986) would increase self-efficacy and self-care in patients with CAD. Method: The study was a one group, pretest-posttest pre-experimental design research. The Self-Efficacy Information Resources Program was composed of a video tape program and a telephone coaching program and based on vicarious experiences and verbal persuation. The Program was used as an experimental treatment from February 27. to May 27, 1999. Twenty patients participated from a university hospital located in Seoul. Three days later after a pretest the telephone coaching program was given. It was repeated weekly during a 3 week period. At the end of this period post-test data were collected by mail. Data were analyzed with a random permutation test using SAS program. Result: 1) Scores on self-efficacy after the Self-Efficacy Information Resources Program were significantly higher than before the program (p=0.06). 2) Scores on self-care after the Program were significantly higher (subjective self-care, p=0.0005; objective self-care, p= 0.0002) than before the program. Conclusion: The Program was found to be an effective nursing intervention for increasing self-efficacy and self-care. When nurses who care for CAD patients plan to increase their patients' self care ability, they should always consider the concept of self-efficacy.

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The Efficacy of Voice Therapy for the Treatment of Vocal Fold Bowing (궁형 성대를 보이는 환자들에 있어 음성치료의 효과)

  • 신혜정;김진경;김은아;고영민;박애경;정성민
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.14 no.2
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    • pp.94-97
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    • 2003
  • Background and Objectives : Bowing of the vocal fold, a bowed edge of the vocal fold results from various disorder causes glottic incompetence resulting in voice disorders. The results of treatment were not satisfactory even though a variety of methods of treatment were applied. The goal of this study is to evaluate of efficacy of the non-surgical, voice therapy in patients with vocal fold bowing. Materials and Method : Twenty two patients of vocal fold bowing not resulting from vocal fold palsy and sulcus vocalis were analyzed. After voice therapy and medical treatment, parameters of perceptual, acoustic, aerodynamic analysis and stroboscopic findings were compared those of pretreatment results. Results and Conclusion : Jitter, shimmer and maximal phonation time were significantly improved and subjective satisfaction was improved in 73% of patients. In the videostroboscopic examination, vocal fold gap was decreased in 27% of patents. The result of this study indicates that voice therapy alone has effect in treatment of vocal fold bowing. Voice therapy is one of the mainstay of treatment of vocal fold bowing.

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The Efficacy of Korean Medical Treatment for Recalcitrant Hand and Foot Warts with an Experience of Cryotherapy (냉동치료 경험이 있는 손과 발의 난치성 사마귀에 대한 한방치료의 효과)

  • Shin, Sang-Ho;Yun, Jeong-Min;Heo, Jeong-Eun;Ko, Woo-Shin;Yoon, Hwa-Jung
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.28 no.2
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    • pp.33-44
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    • 2015
  • Objective : The purpose of this study is to know the efficacy of Korean medical treatment for recalcitrant hand and foot warts with an experience of cryotherapy. Methods : Twenty-two patients(male 12, female 10) with recalcitrant warts visited Amar Korean Medicine Clinic and were treated with herbal medicine, herbal acupuncture, acupuncture, moxibustion and bloodletting for at least 3 months. After treatment, a clearance rate was divided into 4 scales such as; complete clearance / partial clearance-good / partial clearance-poor / no change. Results : Mean age of patients was 23.4 years and mean period of disease was 43.6 months. Mean duration of treatment was 3.0 months and mean dosage(貼) of herbal medicine was 89.1. Nineteen patients(86.4%) showed complete clearance, one(4.5%) partial clearance-good, and two(9.1%) partial clearance-poor. Conclusion : This data demonstrates that Korean medical treatment could be an effective treatment for recalcitrant warts.

Case Series of Hwa-Byung Patients with Facial Spasm - by Using Oriental Medical Treatment with Melonis Calyx Vomiting Therapy (과체 토법 등 한방치료로 호전된 면경련을 동반한 화병환자 3례)

  • Ryu, Ho-Sun;Ahn, Hyo-Jin;Lee, Su-Bin;Park, Se-Jin
    • Journal of Oriental Neuropsychiatry
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    • v.23 no.4
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    • pp.183-198
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    • 2012
  • Objectives : This case series aims to report the efficacy of using oriental medical treatment with Melonis Calyx Vomiting Therapy for Hwa-Byung. Methods : Patients were diagnosed with Hwa-Byung through Hwa-Byung Diagnostic interview schedule (HBDIS). They were treated with Oriental medical treatment (Acupncture, Herb-medication) and Melonis Calyx Vomiting Therapy (MCVT). MCVT is a traditional treatment, which induces vomiting by eating Melonis Calyx powder with water. We used VAS score and Scott scale for the symptoms of patients and IOMEHB (instrument of oriental medical evaluation for Hwa-Byung), BDI, STAI for the psychological conditions of the patients. Results : After treatment, the chief complaint and other symptoms of Hwa-Byung have improved. The scores of IOMEHB, BDI, and STAI have decreased. Conclusions : This result suggests that using MCVT with Oriental medical treatment have a positive efficacy for Hwa-Byung.

A Study on the Skin Improvement Effect of Ginseng Extract with Microneedle Therapy System (미세다륜침을 이용한 인삼추출물의 피부개선 효과연구)

  • Koo, Jin Suk
    • The Korea Journal of Herbology
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    • v.36 no.4
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    • pp.31-39
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    • 2021
  • Objectives : The purpose of this study was to find out the efficacy of ginseng on the skin by comparing the difference effect between only MTS (microneedle therapy system) and the ginseng solution application after MTS treatment. Methods : The present author performed once a week and total 3 times of MTS treatment. The treatment time took about 5~10 minutes and the depth of the needle was adjusted according to the participant's skin condition. In the control group, skin toner was applied after MTS and in the experimental group, ginseng extract dissolved toner was applied. One week after each treatment, the change of skin condition was measured. Two weeks after the end of the clinical trial, the skin condition was checked again. Results : In the case of t-zone oil, there was a significant decrease in the test group and in the case of pores and pigmentation, there was a significant decrease in both the test group and the control group, but the degree of significance was greater in the test group. In the case of skin tone, there was an increase, but no significance. Conclusion : The MTS treatment itself showed good effects on t-zone oil, pores, pigmentation, and skin tone. But the effect was much better when the ginseng extract solution was applied to the skin after MTS treatment. This study suggests that ginseng solution increases the efficacy of MTS.

Review of Recent Researches on the Acupuncture Treatment for Interstitial Cystitis (간질성 방광염의 침 치료에 관한 임상 연구 고찰)

  • Ku, Su-Jeong;Hwang, Deok-Sang;Lee, Jin-Moo;Lee, Chang-Hoon;Jang, Jun-Bock
    • The Journal of Korean Obstetrics and Gynecology
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    • v.32 no.3
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    • pp.86-101
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    • 2019
  • Objectives: This review is aimed at assessing the efficacy and effectiveness of acupuncture treatment for interstitial cystitis patients through literature research and overview. Methods: Database searching was conducted to identify relevant randomized controlled trials (RCTs) and clinical studies on the acupuncture treatment for interstitial cystitis patients. Studies were searched from Journal of Korean Obstetrics and Gynecology, KISS, KMBASE, CNKI, Cochrane library, PubMed and EmBase up to April 2019. Results: Five studies including three RCTs and two clinical studies were finally selected. Three studies showed that acupuncture was effective for interstitial cystitis. One study showed ineffectiveness of acupuncture treatment. Conclusions: From three studies, acupuncture treatment for interstitial cystitis patients showed symptoms relief and improvement of QoL (Quality of Life). Further strictly designed studies are needed to confirm the efficacy and setup the acupuncture treatment protocol.