• 제목/요약/키워드: Transport System

검색결과 4,525건 처리시간 0.033초

Mechanism and Regulation of Amino Acid Transport in Mammary Gland - Review -

  • Kansal, Vinod K.;Sharma, Rekha
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제14권5호
    • /
    • pp.710-719
    • /
    • 2001
  • Several amino acid transport systems in mammary gland have been characterized during the last few years. These systems may be divided into two broad categories based on whether they are sodium-dependent or $Na^{+}$-independent, and each of these categories is subdivided into 3 groups depending on whether the systems prefer zwitterionic, cationic or anionic substrates. The zwitterion preferring transport processes in mammary gland are $Na^{+}$-dependent system A and $Na^{+}$-independent systems L and T. System $y^{+}$ is a $Na^{+}$-independent transporter of cationic amino acids and $X_{AG^{-}}$ is a $Na^{+}$-dependent system for anionic amino acids. A ($Na^{+}+Cl^{-}$)-dependent system, selective for $\beta$-amino acids has been reported in rat mammary tissue. In addition, there is yet another class of transporters that have still broader specificity. The $Na^{+}$-dependent systems $BCl^{-}$-dependent and $BCl^{-}$-independent and $Na^{+}$-independent system $y^{+}L$ have been reported to mediate the transport of zwitterionic as well as cationic amino acids. Each system has been characterized with respect to its substrate specificity, affinity, kinetics and ion-dependence. Transport of amino acids by mammary tissue is regulated by i) the intracellular substrate concentration, ii) lactogenic hormones and iii) milk stasis. Four of the above transport systems (i.e. A, L, $y^{+}$ and $BCl^{-}$-independent) are up-regulated by lactogenic hormones (insulin, cortisol and prolactin) in mammary gland.

우선순위화에 기반한 적응형 전송 기능을 가진 MPEG-4 스트리밍 시스템의 설계 및 구현 (Design and implementation of MPEG-4 streaming system with prioritized adaptive transport)

  • 박상훈;장혜영;권영우;김종원;유웅식;권오형
    • 대한전자공학회:학술대회논문집
    • /
    • 대한전자공학회 2003년도 신호처리소사이어티 추계학술대회 논문집
    • /
    • pp.95-98
    • /
    • 2003
  • To provide high-quality media streaming service over the best-effort Internet, an efficient streaming system with a network-adaptive transport is essential. By adopting FEC-based adaptive transport and by matching it to the priority of media packets, in this paper, an enhanced MPEG-4 streaming system is implemented. The implemented adaptive transport can complement the existing MPEG-4 streaming server with components such as elementary stream provider, sync layer and DMIF layer. Sync layer packets of each MPEG-4 elementary stream are prioritized and then selectively dropped at the sender to match the currently available bandwidth. Also, with the proposed adaptive transport module, the level of FEC protection is dynamically adjusted based on the underlying network condition. With preliminary verification over the emulated network testbed, it is shown that the proposed implementation can mitigate the impact of network fluctuation and thus improve the quality of streaming.

  • PDF

고분자젤 내에서 분자체 거동현상 연구 (Study of Transport Phenomena of Large Ionic - Molecules Inside Polymeric Gel)

  • 박영규;성기천
    • 한국응용과학기술학회지
    • /
    • 제18권1호
    • /
    • pp.1-6
    • /
    • 2001
  • Theoretical model has been studied for the transport phenomena of molecules in the system where an electric potential is applied to the system in the axial direction. The effect of electrophoretic convection in the polymeric media is significantly contributed to separate large ionic-molecules because the conformation of large ionic-molecule quickly orients in the field direction. The dependence of the transport in the polymeric media upon field intensity and molecular size aids in understanding the transport of large ionic-molecule in the system, since the convective velocity of large ionic-molecule is accelerated inside a porous material. The transport distance of individual large ionic-molecule can be predicted using the reptation theories.

Glucose Transport through N-Acetylgalactosamine Phosphotransferase System in Escherichia coli C Strain

  • Kim, Hyun Ju;Jeong, Haeyoung;Lee, Sang Jun
    • Journal of Microbiology and Biotechnology
    • /
    • 제32권8호
    • /
    • pp.1047-1053
    • /
    • 2022
  • When ptsG, a glucose-specific phosphotransferase system (PTS) component, is deleted in Escherichia coli, growth can be severely poor because of the lack of efficient glucose transport. We discovered a new PTS transport system that could transport glucose through the growth-coupled experimental evolution of ptsG-deficient E. coli C strain under anaerobic conditions. Genome sequencing revealed mutations in agaR, which encodes a repressor of N-acetylgalactosamine (Aga) PTS expression in evolved progeny strains. RT-qPCR analysis showed that the expression of Aga PTS gene increased because of the loss-of-function of agaR. We confirmed the efficient Aga PTS-mediated glucose uptake by genetic complementation and anaerobic fermentation. We discussed the discovery of new glucose transporter in terms of different genetic backgrounds of E. coli strains, and the relationship between the pattern of mixed-acids fermentation and glucose transport rate.

부산항 항만 운송과 육상 교통 연계시스템에 관한 경제성 분석 -컨테이너 화물 운송을 중심으로- (Economic Analysis on Inter-Connected System of Port Transport and In-land Transportation -A Container Cargo Transport Oriented-)

  • Kwak, Kyu-Seok;Kim, Tae-Gon;Choi, Jae-Soo;Ahn, Ki-Myung
    • 한국항만학회지
    • /
    • 제5권1호
    • /
    • pp.29-54
    • /
    • 1991
  • In this study, to identify the ineffectiveness of inter-connected system of cargo volume between the Pusan Port and inland areas and also to make more rational suggestions, the following conclusions were drawn by analyzing Container Cargo Traffic from BCTOC to Off-Dock CY: 1. There existed about 30% to 50% reduction in the container transport times when the container transport vehicles were operated during the off-peak period to alleviate the traffic congestion due to mixed traffic. 2. There appeared to be more economic when Off-Dock DY's scattered around the City of Pusan were unified in one ODCY Unit at YangSan, and the Exclusive Overpass Freeway System for the container transport vehicles were constructed and operated on the existing Urban Freeway from BCTOC ti this ODCY Unit (Expected to make about 230 billions Won in net present value by NPV method).

  • PDF

유해화학물질 운반차량 관리제도 실효성 연구 (A Study on the Effectiveness of the Hazardous Chemical Transport Vehicle Management System)

  • 김성범;이현승;정성경
    • 한국재난정보학회 논문집
    • /
    • 제17권4호
    • /
    • pp.794-801
    • /
    • 2021
  • 연구목적: 화관법의 운반차량 관리제도 실효성을 연구하여 제도 개선방안을 위한 기초자료로 활용하고자 한다. 연구방법: 화관법('15.1.1) 시행 이후 운반차량관리 제도인 운반계획서, 지도점검 현황, 안전교육 이수 관리 등과 화학사고 감소 비율을 비교하여 실효성을 연구하였다. 연구결과: 화관법 시행 초반('15~'17년) 운반차량에 의한 화학사고 평균 건수는 20건에서 13건('18~'20년)으로 평균 7건이 줄었다. 화학사고 감소원인으로는 첫째 지도·점검률이 해마다 높아지면서 사업장에서 화관법에 대한 관심이 높아지고, 화학물질 운반차량에 대한 검사가 주기적으로 이루어지는 등 차량 시설결합에 의한 화학사고가 줄었다. 둘째, 운반계획서 제출량이 매년 증가하면서 운반계획서 검토 및 확인 등을 통해 운반자가 운반하는 물질에 대한 정보를 직·간접적으로 확인하였고, 이로 인해 화학물질 이송 시 유의하여 운행하는 등의 간접적인 영향을 끼친 것으로 판단된다. 마지막으로 안전교육을 통해 운반물질의 위험성 인지, 개인보호장구 구비, 화학사고 발생 시 책임소재 인식 변화로 운반차량에 의한 화학사고는 감소하는 것으로 판단된다. 결론: 현재 시행되고 있는 화관법의 운반차량 관리제도는 실효성을 보이고 있지만, '18년 이후 사고가 소폭 증가하는 경향을 보여서 추후 실용적이며 효율적인 운반차량 관리제도 개선을 위한 추가적인 연구가 필요하다.

초음파를 이용한 물체 이송시스템의 동작특성 연구 (A Study on the Dynamic Characteristics of Object Transport System using Ultrasonic Wave)

  • 정상화;김현욱;차경래;최석봉;송석
    • 한국정밀공학회지
    • /
    • 제22권8호
    • /
    • pp.151-158
    • /
    • 2005
  • In the semiconductor and the optical industry, a new transport system which can replace the conventional sliding systems is required. The sliding systems are driven by the magnetic field and conveyer belts. The magnetic field nay damage semiconductor and the contact force may scratch the optical lens. The ultrasonic wave driven system can solve these problems. In this paper, an object transport system using the excitation of ultrasonic wave is proposed. The experiments for finding the optimal progressive frequency and the phase-differences between two ultrasonic wave generators are performed. The relationships between transportation speed and the excitation frequency, flexural beam shapes and amplification voltage are investigated.

제어기 무장착 운송대를 위한 선형운동 자기부상 운송시스템 (Magnetically levitated transport system for a controller-free carrier)

  • 손영욱;박기환
    • 대한기계학회논문집A
    • /
    • 제21권12호
    • /
    • pp.2196-2208
    • /
    • 1997
  • In this work, a magnetic levitation (maglev) system is developed to transport a wafer between semiconductor fabrication process modules in clean rooms to take advantages of eliminating particle and oil contamination that normally exist in conventional transport systems due to contact motion of mechanical components. A main feature of the maglev system developed in this work is that a controller and power supplying part are not mounted on the moving carrier but on the stationary track, which is defined a controller-free carrier, to reduce carrier's weight. Iron-core electromagnets and irons are used for levitation, and air-core electromagnets and permanent magnets are used for stabilization. Analysis, design, and modeling of the magnetically levitated transport system are presented. The performance of the maglev system is experimentally demonstrated.

A Study on the Inhibition of 2-deoxy-D-Glucose Transport of the Endogenous Glucose Transporters in Spodoptera frugiperda Clone 21-AE Cells by Using Hexoses

  • Lee Chong-Kee
    • 대한의생명과학회지
    • /
    • 제11권4호
    • /
    • pp.487-492
    • /
    • 2005
  • The baculovirus/insect cell expression system is of great value in the study of structure-function relationships in mammalian glucose-transport proteins by site-directed mutagenesis and for the large-scale production of these proteins for mechanistic and biochemical studies. Spodoptera frugiperda Clone 21 (Sf2l) cells grow well on TC-100 medium that contains $0.1\%$ D-glucose as the major carbon source, strongly suggesting the presence of endogenous glucose transporters. However, very little is known about the properties of the endogenous sugar transporter(s) in Sf2l cells, although a saturable transport system for hexose uptake has been previously revealed in the Sf cells. In order to further examine the substrate and inhibitor recognition properties of the Sf2l cell transporter, the ability of hexoses to inhibit 2-deoxy-D-glucose (2dGlc) transport was investigated by measuring inhibition constants $(K_i)$. The $K_i's$ for reversible inhibitors were determined from plots of uptake versus inhibitor concentration. Transport was effectively inhibited by D-mannose and D-glucose. Of the hexoses tested, L-glucose had the least effect on 2dGlc transport in the Sf2l cells, indicating that the transport is stereoselective. Unlike the human HepG2 type glucose transport system, D-mannose had a somewhat greater affinity for the Sf2l cell transporter than D-glucose, implying that the hydroxyl group at the C-2 position is not necessary for strong binding. However, epimerization at the C-4 position of D-glucose (D-galactose) resulted in a dramatic decrease in affinity of the hexose for the Sf2l cell transporter. Such a lowering of affinity might be the result of the involvement of the C-4 hydroxyl in hydrogen bonding. It is therefore suggested that Sf2l cells were found to contain an endogenous sugar transport activity that in several aspects resembles the human HepG2 type glucose transporter, although the insect and human transporters do differ in their affinity for cytochalasin B.

  • PDF

KN-12 운반용기를 이용한 고리 사용후핵연료 소내수송.저장 (On-Site Transport and Storage of Spent Nuclear Fuel at Kori NPP by KN-12 Transport Cask)

  • 정성환;백창열;최병일;양계형;이대기
    • 방사성폐기물학회지
    • /
    • 제4권1호
    • /
    • pp.51-58
    • /
    • 2006
  • 고리 원전 사용후핵연료 저장조의 저장용량을 확보하기 위하여 2002년부터 사용후핵연료 운반용기를 이용하여 400다발 이상의 PWR 사용후핵연료 집합체를 원전부지 내에 수송, 저장하였다. 이를 위하여 KN-12 운반용기, 관련장비 및 수송차량으로 구성되는 수송시스템을 구성하였다. KN-12 운반용기는 국내 원자력법 및 IAEA의 수송규정에 따라 설계, 제작되고, 정부로부터 인허가를 획득하였으며, 취급장비 역시 관련규정에 따라 구비하였다. 수송 저장작업은 2 대의 운반용기를 동시에 투입하여 수행하였으며, 모든 작업공정에 대하여 엄격한 품질관리 및 방사선 안전관리를 수행하여 수송 안전성을 확보하고 신뢰도를 제고하였다.

  • PDF