• 농촌의학ㆍ지역보건
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• 제8권1호
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• pp.44-65
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• 1983

As a part of the epidemiological studies of clonorchiasis, this study was conducted to evaluate the current endemicity and the natural transition of the Clonorchis infection in Gimhae Gun and delta area a high endemic area in Korea in recent years, prior to the introduction of praziquantel which will eventually influence the status of the prevalence. The data obtained in this study in 1983 were evaluated for natural transition of the infection in comparison with those obtained 16 years ago in 1967 by the author(Kim, 1974). The areas of investigation, villages and schools surveyed, methods and techniques used in this study were the same as in 1967, except for the contents of the questionnaire for raw freshwater fish consumption by the local inhabitants. 1) The prevalence rate of clonorchiasis in the general population of the villages was 48.1% on the average out of a total of 484 persons examined. The average of those of the riverside-delta area was 65.2% and 43.0% in the inland area. Among the schoolchildren, the prevalence rate was 8.2% on the average out of a total of 1,423 examined. By area, the prevalence rate was 10.8% in the riverside delta area and 2.8% in the inland area. By sex, difference in the prevalence was seen only in the inhabitants of the inland area showing 52.4% in the male and 33.5% in the female. 2) In the natural transition of the infection, the prevalence rate among the inhabitants has decreased from 68.8% in 1967 to 48.1% in 1983, and in the schoolchildren from 56.4% in 1967 to 8.2% in 1983. The reduction rate was higher in the riverside-delta area than in the inland area. 3) In the prevalence rate by age, 11.9% was first seen in the 5-9 age group and the rate gradually increased up to 75.0% in the 50-59 age group. By sex, the rate was higher in the male than in the female in the 20-29 age group and over. 4) In the natural transition of the prevalence rate by age, the reduction rate of the infection during the past 16 years was greater in the younger age groups up to the 40-49 age group and reached the same level in the age group 50-59. Reduction was seen again in the age group over 60s. By sex, the reduction rate was greater in the female than in the male in the 20-29 age group and over. By area, the reduction rate was greater in the riverside delta area than in the inland area, particularly in the young age groups. 5) In the intensity of the infection among the cases, the mean egg out-put per mg feces per infected cases(EPmg) in the inhabitants was 6.3. EPmg of those of the river-side-delta area was 15.4 and that of the in-land was 2.8. On the other hand, in the schoolchildren, EPmg was 3.2, and no difference was seen between the two areas, the river-side-delta area and the inland area. 6) In the transition of the intensity of the infection by area, EPmg among the inhabitants inexplically increased from 7.8 in 1967 to 15.4 in 1983. This was probably caused by uneven specimen collection in the process of sampling the population. EPmg of the inhabitants in the inland area and those of the schoolchildren of both riverside delta and inland areas showed a similar decrease in the past 16 years. 7) The intensity of the infection by age showed a relatively low level in the 20-29 age group and below, and EPmg 5.1-9.5 was seen in the 30-39 age group and over. Sex, Epmg was 5.8 in the male and 4.7 the female. By in 8) In the transition of the intensity of the infection, EPmg decreased from 6.2 in 1967 to 5.4 in 1983. By age, in contrast to the figures of 1967 in which EPmg gradually increased with some fluctuation from 1.1 in the 0-4 age group to peak 10.5 in the 50-59 age group, in 1983 lower intensity of the infection was seen in the age group from 10-14 to 20-29 with the EPmg range of 0.6-2.7. 9) In the distribution of the clonorchiasis cases by the range of EPmg value, 43.2% of the cases were in 0.1 0.9 and 34.6% in 1.0-4.9. As a whole by cumulative percent, 44.6% of them were under 0.9 as light infection and 86.1% of them under 9.9 up to moderate infection. By sex, no difference was seen in Epmg. 10) In the transition of the distribution by the range of Epmg, the cases were distributed up to the range 80.0-99.9 in 1967 and to 60.0-79.9 in 1983. By cumulative percent, in the range of 0.1-0.9 and less, light infection, 34.3% of them were distributed in 1967 and 44.6% in 1983 with about 10% increase. In the range of 5.0-9.9 and less, up to moderate infection, 83.2% in 1967 and 86.1% in 1983 of the cases were seen, respectively. 11) The practice of raw freshwater fish consumption among the inhabitants seems to have decreased in recent years. Those who admitted to raw freshwater fish consumption in the last two years among the infected inhabitants were 59.3%, although 86.8% of them professed to have experience with raw freshwater fish consumption. 31.7% of those who have had experience of the raw freshwater fish consumption denied any further consumption in recent years. From an interview of 543 school-children, 24.1% of them admitted to an experience of raw freshwater fish consumption. However, those who have practised in the past two years comprized 17.9%. Those who denied raw freshwater fish consumption in recent years among those who had such experience were 26.0% out of 131 interviewed. The rate of raw freshwater fish consumption in both inhabitants and schoolchildren were higher in the male than in the female. On the contrary, the rate of those who did not practise in recent years among those who had experience of raw freshwater fish consumption was higher in the female than in the male. 12) The major reason for the reduction of raw freshwater fish consumption among the local inhabitants was the risk of the fluke infection. However, it has become apparent that such change of taste has resulted from water pollution impact which has affected throughout the areas of the freshwater systems in this locality since last several years. 13) In animal survey, Clonorchis infection was seen in 14.8% of 88 dogs examined and 3.7% of 27 house rats examined. It was noted that populations of dogs and cats have increased in the villages surveyed. Although the prevalence rate was lower in the present survey than those of 1967, the significance of the animals as the reservoir host has not changed. 14) Prevalence rate of Clonorchis infection by cercariae in the first intermediate host, Parafossarulus manchouricus, was 0.6% out of 517 snails examined. The infection rate was lower in comparison with 2.3% out of 2,124 examined in 1967. Moreover, sharp decreases in number and distribution of the intermediate host snails in many watershed areas of the huge freshwater systems in this locality seemed to reduce transmission of Clonorchis in connection with the intermediate host stage of its life cycle. 15) Clonorchis infection in the second intermediate fish hosts was relatively low. The mean number of Clonorchis metacercaria per fish in Pseudorasbora parva was 517 in 1983, whereas it was 1943 in 1968 through 1969. Environmental water pollution has also caused the decreased fish population density in these areas, and this has also apparently affected to the practice of raw freshwater fish consumption among the local inhabitants. 16) In conclusion, endemicity of Clonorchis infection in Gimhae Gum and delta area of the Nagdong River has sharply decreased during the past 16 years. The major cause of the regressive transition of the infection was the water pollution of the land water systems of this locality. The pollution has upset the ecosystems comprizing of the intermediate hosts of Clonorchis in many areas, and also affected to a significant extent to the discontinuance of the local inhabitants for raw freshwater fish consumption.

• Molecules and Cells
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• 제20권1호
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• pp.69-73
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• 2005

The flavonoid, quercetin, is a low molecular weight substance found in apple, tomato and other fruit. Besides its antioxidative effect, quercetin, like other flavonoids, has a wide range of neuropharmacological actions including analgesia, and motility, sleep, anticonvulsant, sedative and anxiolytic effects. In the present study, we investigated its effect on mouse 5-hydroxytryptamine type 3 ($5-HT_{3A}$) receptor channel activity, which is involved in pain transmission, analgesia, vomiting, and mood disorders. The $5-HT_{3A}$ receptor was expressed in Xenopus oocytes, and the current was measured with the two-electrode voltage clamp technique. In oocytes injected with $5-HT_{3A}$ receptor cRNA, quercetin inhibited the 5-HT-induced inward peak current ($I_{5-HT}$) with an $IC_{50}$ of $64.7{\pm}2.2{\mu}M$. Inhibition was competitive and voltage-independent. Point mutations of pre-transmembrane domain 1 (pre-TM1) such as R222T and R222A, but not R222D, R222E and R222K, abolished inhibition, indicating that quercetin interacts with the pre-TM1 of the $5-HT_{3A}$ receptor.

• 한국ITS학회 논문지
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• 제7권3호
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• pp.62-73
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• 2008

본 논문에서는 능동방식의 870 nm 적외선 및 5.8 GHz 주파수 통합방식으로 운영되는 고속도로 자동 요금징수 시스템의 능동주파수방식에 대한 국내 표준 개선방안을 제시한 것으로 2007년말 전국에서 운영되고 있다. 본 표준 개선방안은 5.8 GHz 대역의 ITS전용 단거리 무선통신 표준 중 개방형 시스템간 상호접속 참조모델을 기준하여 OSI 1, 2, 7 계층 중 차량단말기와 노변장치간 다중접속을 위한 상호호환성을 제공하는 물리계층을 중심으로 실제 운영중인 시스템 개선방안을 도출하였다. 즉, 기존 표준에서 복사전력의 경우 전송거리에 따라 Class1 (10 m이내)과 Class2 (100 m 이내)로 구분하였으나 Class1 단일규격으로 2004년 정보통신부고시에 의거하여 운영되고 있고, 통신영역내의 입사전력 한계치의 경우 실제 운영중인 자동 요금징수시스템의 운영방안을 고려하여 측정 결과치를 표준에 반영하도록 하였다. 즉, 자동 요금징수 시스템 운영상 필요한 부분에 대해 사업자 시스템간의 호환성 및 안정성을 확보하기 위해서 복사전력, 통신영역에서의 입사전력, 의사응답의 표준개선을 제안하였다.

• 한국정보통신학회논문지
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• 제7권1호
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• pp.19-25
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• 2003

해안국에서는 기존의 SSB와 VHF 송수신기에 의한 무선통신은 아직도 매우 유효하게 사용하고 있다. SSB와 VHF의 장비는 해상과 육상에서 정보전달에 매우 중요하다. 해안국과 터미널간에 있어서 기존 SSB와 VHF 송수신기에 의한 통신상대는 1:1 방식이다. 그러나 이 1:1의 방식을 1대 다수로 한다. 그러면 주파수를 아낄 수 있고, 또 해상에서 조난, 긴급, 안전통신 및 군용통신에서 효과적으로 할 수 있다. 또 1대 다수방식은 인터럽트를 할 수 있다. 그것은 중요통신의 신속한 전송에 편리하다. 이 장비를 VHF 통신에 설치하면 원거리에 있는 선박과 양호한 통신을 할 수 있다. 그러므로 이 방식은 통신범위를 넓힐 수 있다. ICS에 의한 회선교환 방법은 PPT 신호와 음성신호가 변조된 ASK로 원격조정을 한다. ICS는 회선교환기를 통하여 단말기와 송수신기의 접속을 수시로 변경할 수 있다. 이렇게 하기 위해서 ASK방식에 대한 정보전송, ICS의 시스템 개발, 제어 알고리즘의 구현, 멀티프로세서의 시스템 개발, 전송방식, 모니터링을 연구하였다 그리고 실험을 통하여 실 제품까지 제작하였다. 따라서 이 논문은 원격제어를 위한 무선통신장비의 회선교환 제어방식으로서 해상통신, 군용통신, 어업통신 등을 위한 무선국 통신장비의 개선에 기여도가 클 것으로 기대된다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2012년도 제43회 하계 정기 학술대회 초록집
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• pp.254-255
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• 2012

Interest in nano-crystalline silicon (nc-Si) thin films has been growing because of their favorable processing conditions for certain electronic devices. In particular, there has been an increase in the use of nc-Si thin films in photovoltaics for large solar cell panels and in thin film transistors for large flat panel displays. One of the most important material properties for these device applications is the macroscopic charge-carrier mobility. Hydrogenated amorphous silicon (a-Si:H) or nc-Si is a basic material in thin film transistors (TFTs). However, a-Si:H based devices have low carrier mobility and bias instability due to their metastable properties. The large number of trap sites and incomplete hydrogen passivation of a-Si:H film produce limited carrier transport. The basic electrical properties, including the carrier mobility and stability, of nc-Si TFTs might be superior to those of a-Si:H thin film. However, typical nc-Si thin films tend to have mobilities similar to a-Si films, although changes in the processing conditions can enhance the mobility. In polycrystalline silicon (poly-Si) thin films, the performance of the devices is strongly influenced by the boundaries between neighboring crystalline grains. These grain boundaries limit the conductance of macroscopic regions comprised of multiple grains. In much of the work on poly-Si thin films, it was shown that the performance of TFTs was largely determined by the number and location of the grain boundaries within the channel. Hence, efforts were made to reduce the total number of grain boundaries by increasing the average grain size. However, even a small number of grain boundaries can significantly reduce the macroscopic charge carrier mobility. The nano-crystalline or polymorphous-Si development for TFT and solar cells have been employed to compensate for disadvantage inherent to a-Si and micro-crystalline silicon (${\mu}$-Si). Recently, a novel process for deposition of nano-crystralline silicon (nc-Si) thin films at room temperature was developed using neutral beam assisted chemical vapor deposition (NBaCVD) with a neutral particle beam (NPB) source, which controls the energy of incident neutral particles in the range of 1~300 eV in order to enhance the atomic activation and crystalline of thin films at room temperature. In previous our experiments, we verified favorable properties of nc-Si thin films for certain electronic devices. During the formation of the nc-Si thin films by the NBaCVD with various process conditions, NPB energy directly controlled by the reflector bias and effectively increased crystal fraction (~80%) by uniformly distributed nc grains with 3~10 nm size. The more resent work on nc-Si thin film transistors (TFT) was done. We identified the performance of nc-Si TFT active channeal layers. The dependence of the performance of nc-Si TFT on the primary process parameters is explored. Raman, FT-IR and transmission electron microscope (TEM) were used to study the microstructures and the crystalline volume fraction of nc-Si films. The electric properties were investigated on Cr/SiO2/nc-Si metal-oxide-semiconductor (MOS) capacitors.

• 폴리머
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• 제39권1호
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• pp.88-98
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• 2015

폴리이미드(PI) 나노복합체 필름 제조에 사용된 작용기화 4-amino-N-hexadecylbenzamide graphene sheets (AHB-GSs)는 graphene oxide 분산액에 4-amino-N-hexadecylbenzamide(AHB)를 반응시켜 합성하였다. AHB-GS의 주사탐침 현미경(atomic force microscope, AFM) 이미지와 모식도를 통해서 AHB-GS의 평균 두께가 약 3.21 nm임을 확인하였다. PI는 4,4'-biphthalic anhydride와 bis(4-aminophenyl)sulfide를 사용하여 합성하였다. PI 나노복합체는 0-10 wt%의 다양한 함량의 AHB-GS를 용액 삽입(solution intercalation) 방법을 사용하여 합성하였고, 이미드화는 각각 $250^{\circ}C$ 및 $350^{\circ}C$까지 열 처리하였다. AHB-GS는 대부분 고분자 매트릭스에 잘 분산되었고 약간 뭉친 것도 있었지만 마이크로미터 수준의 입자는 관찰되지 않았다. TEM으로 관찰하였을 때, 평균적으로 입자의 두께는 10 nm 미만이었다. PI 복합체 필름 중 소량의 AHB-GS만으로도 가스 투과도와 전기 전도도는 향상되었지만, 반대로 유리전이 온도와 초기 분해 온도는 AHB-GS의 함량이 10 wt%까지 증가함에 따라 지속적으로 감소되는 경향을 보였다. 전체적으로는, $250^{\circ}C$까지 이미드화한 PI에 비해 $350^{\circ}C$까지 열처리한 PI 필름이 보다 향상된 특성을 보였다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2009년도 추계학술대회 논문집
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• pp.114-114
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• 2009

ZnO has received considerable attention due to its potential applicability to optoelectronic devices such as ultraviolet-light emitting diodes (UVLEDs) and laser diodes (LDs). As well known, however, polar ZnO with the growth direction along the c-axis has spontaneous and piezoelectric polarizations that will result in decreased quantum efficiency. Recently, nonpolar ZnO has been studied to avoid such a polarization effect. In order to realize applications of nonpoar ZnO-based films to LEDs, growth of high quality alloys for quantum well structures is one of the important tasks that should be solved. $Mg_xZn_{1-x}O$ and $Cd_xZn_{1-x}O$ is ones of most promising alloys for this application because the alloys of ZnO with MgO and CdO provide a wide range of band-gap engineering spanning from 2.4 to 7.8 eV. In this study, we investigated on $Mg_xZn_{1-x}O$ films grown with various Mg/Zn flux ratios The films were grown on R-plane sapphire substrates by plasma-assisted molecular beam epitaxy (PAMBE). we investigated on $Mg_xZn_{1-x}O$ films grown with various Mg/Zn flux ratios. The films were grown on R-plane sapphire substrates by plasma-assisted molecular beam epitaxy (PAMBE). With the relatively low Mg/Zn flux ratios, a typical striated anisotropic surface morphology which was generally observed from the nonpolar (11-20) ZnO film on r-plane sapphire substrates. By increasing the Mg/Zn flux ratio, however, additional islands were appeared on the surface and finally the surface morphology was entirely changed, which was generally observed for the (0001) polar ZnO films by losing the striated morphology. Investigations by X-ray $\Theta-2{\Theta}$ diffraction revealed that (0002) and (10-11) ZnO planes are appeared in $Mg_xZn_{1-x}O$ films by increasing the Mg/Zn flux ratio. Further detailed investigation by transmission electron microscopy (TEM) and photoluminescence (PL) will be discussed.

• 대한전자공학회논문지TC
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• 제45권10호
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• pp.65-70
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• 2008

본 연구에서는 94 GHz 송수신 시스템에 응용이 가능한 평면형 회로 내의 전송 선로 방식의 하나인 CPW(Coplanar Waveguide)와 구형 도파관 간의 신호를 원활히 전달해주는 94 GHz CPW-구형 도파관 변환기를 설계하고 제작하였다. 제안된 변환기는 단일 면에 구현된 Fin-line 테이퍼와 Open 타입의 CPW-Slot-line 변환기 구조로 구성되어 있으며, 이는 MMIC의 플립칩 본딩을 위해 기존의 MMIC 기술을 이용하여 단단하고 구부러지지 않는 사파이어($Al_2O_3$)기판위에 구현되었다. Ansoft사의 HFSS 툴을 이용하여 최적화된 Single-section 변환기를 Back-to-back 구조의 지그로 제작하였고 Anritsu ME7808A Vector Network Analyzer 장비를 이용해 $85{\sim}105$ GHz를 대역에서 S-파라미터들을 측정하였다. 측정 결과, 3 mm 길이를 갖는 CPW의 삽입 손실을 고려하여 94 GHz에서 약 1.7 dB의 삽입 손실과 25 dB 이상의 반사손실을 확인 하였다.

• 인터넷정보학회논문지
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• 제16권3호
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• pp.1-11
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• 2015

인체를 중심으로 동작하는 WBAN(Wireless Body Area Network)은 의료 및 비의료 서비스를 동시에 제공하는 것을 목적으로 하며, 저전력, 다양한 전송률과 높은 데이터 신뢰성을 요구하는 근거리 통신 기술이다. 이러한 요구사항을 만족시킬 수 있는 통신기술 표준 중 IEEE 802.15.4는 WBAN 운영에 높은 호환성을 제공할 수 있어 이를 통한 다양한 연구가 진행되고 있다. 한편, IEEE 802.15.4 기반 다수의 WBAN이 밀집될 경우 발생하는 신호 간섭과 충돌은 데이터의 신뢰성을 저하시키는 주요한 원인되고 있으며, IEEE 802.15.4 표준은 다수의 네트워크가 공존하는 상황을 고려하여 설계되지 않았기 때문에 이에 대한 개선이 필요하다. 이를 해결하기 위해 본 논문에서는 사전 실험을 통해 IEEE 802.15.4 기반의 WBAN 간 공존 상황에서 발생할 수 있는 문제점들을 파악하였고, 실험 결과를 바탕으로 다수의 WBAN이 공존하는 상황에서의 신뢰성 저하를 완화하기 위한 기법을 제안한다. 제안하는 기법의 동작은 크게 두 단계로 구분될 수 있으며, 첫 번째 단계에서는 슈퍼 프레임의 CFP 구간에서의 데이터 전송 방법을 개선하여 WBAN 간 충돌을 회피하며, 두 번째 단계에서는 채널 접근 방식을 전환함으로써 충돌을 완화한다. 제안하는 기법은 표준 기반의 WBAN과 비교 실험을 수행하여 성능을 검증하였다.

• 한국지반신소재학회논문집
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• 제16권4호
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• pp.21-31
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• 2017

식생토낭 공법은 토목섬유 콘테이너 공법의 일종으로 옹벽건설시 시공환경에 따른 영향을 최소화할 수 있으며, 자연친화적 공법이다. 본 연구에서는 식생토낭 보강토벽 시공방법을 식생토낭 비다짐 옹벽, 식생토낭 다짐 옹벽, 중력및 일반쌓기 혼용 옹벽, 게비온과 일반쌓기 혼용 옹벽 등 4가지 시공방법 대하여 계측기를 매설하고, 식생토낭 보강토벽의 거동특성을 평가하였다. 시공계측 결과, 식생토낭 일반쌓기 비다짐 구간에서의 변위가 게비온과 식생토낭 혼용구간 보다 최대 30%이상 발생하였다. 또한, 뒤채움부 무보강 2m이상 식생토낭 보강토벽은 변위에 대해 불안정한 것으로 평가되었다. 한편, 토압의 분포는 시공직후 모든 구간 Rankine 및 Coulomb의 주동토압 이내에 분포하는 것으로 나타났다. 그러나 집중강우 이후 일반쌓기 구간은 토압의 증가폭이 크게 나타났으며, 게비온과 일반쌓기 혼용구간이 일반쌓기 구간과 비교하여 보다 안정한 것으로 평가되었다.