• Journal of Educational Research in Mathematics
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• v.26 no.1
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• pp.143-157
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• 2016

This study aims to find out the feasibility and effectiveness of mathematical games as a way to provide primary pre-service teachers with doing mathematics. The game had induced the active participation of elementary pre-service teachers. Through transforming the game, the teachers have been able to experience of mathematical problem posing and generating mathematical representation. Based on this, we discuss the role of mathematical games as a method of pre-service teacher education.

• Research in Mathematical Education
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• v.6 no.1
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• pp.53-63
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• 2002

This study investigates the impact of Calculator-Based Ranger (CBR) activities in the performance of middle school students' graphing abilities of physical phenomena. Two issues about CBR activities on graphing abilities were addressed in this study; (1) the effect of CBR activities on graphing abilities, and (2) the influence of instructional styles on students' graphing abilities. Following the use of CBR activities, students' graphing abilities were significantly more developed in three components-interpreting, modeling, and transforming. Significant differences were found in students' achievement depending on instructional styles related to differentiation, which is closely connected to transforming distance-time graphs to velocity-time graphs. The findings of this study indicate that CBR activities may enhance students in constructing appropriate webs of related concepts and ability to qualitatively interpret graphs. Using collaborative CBR activities to introduce and explore graphing of physical phenomena is, therefore, recommended for inclusion in the secondary mathematics curriculum.

• The Microorganisms and Industry
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• v.16 no.3
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• pp.2-5
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• 1990

IgA is the predominant immunoglobulin isotype in mucosal secretions(1). It has been reported that a population of Peyer's patch T cells can selectively induce IgM bearing B cells to switch to surface IgA bearing B cells(2,3). Further, IL-4, IL-5, and IL-6 alone and in combination, can significantly influence murine IgA B cell differentiation in vitro(4-7). However, it remains an open question which cytokines have a major role in class switching to the IgA isotype. Recently, it has been reported that transforming growth factor .betha.1(TGF .betha.1) alone, or in combination with IL-2 increases IgA secretion by LPS-activated surface IgA negative (sIgA$\^$-/) murine spleen B cells while concurrently downregulating IgM and IgG secretion by such cells(8-11). In the present study, limiting dilution analysis was used to demonstrate, at the clonal level, that TGF .betha.1 has siginificant activity as an IgA isotype switch factor.

• Journal of the Korean Society for Precision Engineering
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• v.21 no.12
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• pp.154-159
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• 2004

This study is aimed to diminish the errors which created during transforming from 3D shape created with CAD program to STL file formation. The length strain which created on X-Y axises at STL file transforming is diminished by using the relation between common shape error and shrinkage rate. As the result of study, we have confirmed the length strain in accordance with facetres value. Also, the shape error is compensated with shrinkage rate by error of length strain. so, we could diminish to shape error by several tens micrometer.

• Management Science and Financial Engineering
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• v.16 no.3
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• pp.71-84
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• 2010

In this study, we present the exact methods of transforming the continuous solutions into the discrete ones for two types of bit-loading problem, marginal adaptive (MA) and rate adaptive (RA) problem, in multicarrier communication systems. While the computational complexity of existing solution methods for discrete optimal solutions depends on the number of bits to be assigned (R), the proposed method determined by the number of subcarriers (N), making ours be more efficient in most cases where R is much larger than N. Furthermore our methods have some strength of their simpler form to make a practical use.

• Radiation Oncology Journal
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• v.32 no.3
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• pp.208-212
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• 2014

Marfan syndrome is one of the collagen vascular diseases that theoretically predisposes patients to excessive radiation-induced fibrosis yet there is minimal published literature regarding this clinical scenario. We present a patient with a history of Marfan syndrome requiring radiation for a diagnosis of a right brachial plexus malignant nerve sheath tumor. It has been suggested that plasma transforming growth factor beta 1 (TGF-${\beta}1$) can be monitored as a predictor of subsequent fibrosis in this population of high risk patients. We therefore monitored the patient's TGF-${\beta}1$ level during and after treatment. Despite maintaining stable levels of plasma TGF-${\beta}1$, our patient still developed extensive fibrosis resulting in impaired range of motion. Our case reports presents a review of the literature of patients with Marfan syndrome requiring radiation therapy and the limitations of serum markers on predicting long-term toxicity.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.11 no.6
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• pp.421-429
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• 1986

In this paper, new hybrid-pattern recognition system is proposed using Radon transform. Transforming the 2-D image into the 1-D projection data, Fourier spectrum at each projection angle is obtained by the Fourier transforming the projection data using the A/0. After extracting the suitable features from the Fourier spectrum and projection data, the input pattern is recognized using the wquared Mahalanobis distance. The results of this system showed the 100% recognition rate for the 10 input patterns.

• The Journal of Natural Sciences
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• v.15 no.1
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• pp.89-95
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• 2005

JSRV, which causes sheep lung cancer, is known to have the transforming activity of NIH3T3 cells. Especially Envelope protein of this virus has the transforming activity to NIH3T3. To know the effects on the transcriptional activity of transcription factors by this viral protein transient transfection was performed by using the luciferase reporter system. The result showed that JSRV Envelope protein increased the transcriptional activity of NF-kB and AP-1.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1992.05a
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• pp.42-42
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• 1992

ras oncogene은 암조직이나 transformed human cell line에서 거의 공통적으로 발견되는 oncogene으로서 그 product인 p2l 단백질은 C-terminal 25개의 아미노산 외에는 거의 동일한 배열을 가지고 있는 매우 conservative한 단백질이며 C-terminal cysteine이 carboxy methylation되어 있고 또한 palmitic acid와 같은 long chain fatty acid도 결합되어 있다. 보고된 바에 의하면 p21 protein의 palmitation은 ras protein의 세포막에 대한 친화력을 유지시키며 이와 같은 친화력은 cell transforming activity의 기본요건으로 알려져 있다. 이와 같은 관점에서 볼때 p21 단백질의 C-terminal processing현상을 new drug target으로, 즉 p2l 단백질의 C-terminal processing을 억제하므로서 cell transforming activity를 저해 할 수 있을 것이므로 생체내에 존재하는 p21 단백질 C-terminal processing 억제제의 identification 및 purification은 항암제 연구와 밀접한 관계가 있다. 구체적으로 farnesyl-protein transferase inhibitor 혹은 carboxyl methyl inhibitor의 identification 및 purification은 이같은 목적을 달성 할 수 있는 가능성이 크다.

• Journal of Veterinary Clinics
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• v.11 no.1
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• pp.389-392
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• 1994

To purify transforming growth factor type beta(TGF-$\beta$) in canine platelets, Sephadex G-75 gel filtration and semipreparative HPLC were carried out. The column of $2.0 {\times}120cm$ was used for gel filtration and one inch semipreparative column filled with SP-Toyopeal for HPLC. Electrophoresis and bioassay using African green monkey kidney cell were used for identification of TGF-$\beta$ Crude TGF-$\beta$ of 2.75mg was extracted from 5.2g of the platelets by the treatment of acid/ethanol. In gel filtration of crude TGF-$\beta$, 4 peaks were observed at the detection of spectrophotometer at 280nm. Electrophoresis and bioassay identified the 3rd peak TGF-$\beta$. Linear gradient elution from 0 to 3M NaCl in sornipreparative HPLC showed TGF-$\beta$ at 1.5M NaCl. Gel filtration was less expensive and useful method for the purification of TGF-$\beta$.