• Journal of Chest Surgery
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• 제44권6호
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• pp.406-412
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• 2011

Background: Development of thoracic aortic aneurysms and aortic dissections (TAAD) is attributed to unbearable wall tension superimposed on defective aortic wall integrity and impaired aortic repair mechanisms. Central to this repair mechanisms are well-balanced and adequately functional cellular components of the aortic wall, including endothelial cells, smooth muscle cells (SMCs), inflammatory cells, and adventitial fibroblasts. Adventitial fibroblasts naturally produce aortic extracellular matrix (ECM), and, when aortic wall is injured, they can be transformed into SMCs, which in turn are involved in aortic remodeling. We postulated the hypothesis that adventitial fibroblasts in patients with TAAD may have defects in ECM production and SMC transformation. Materials and Methods: Adventitial fibroblasts were procured from the adventitial layer of fresh aortic tissues of patients with TAAD (Group I) and of multi-organ donors (Group II), and 4-passage cell culture was performed prior to the experiment. To assess ECM production, cells were treated with TNF-${\alpha}$ (50 pM) and the expression of MMP-2/MMP-3 was analyzed using western blot technique. To assess SMC transformation capacity, cells were treated with TGF-${\beta}1$ and expression of SM ${\alpha}$-actin, SM-MHC, Ki-67 and SM calponin was evaluated using western blot technique. Fibroblasts were then treated with TGF-${\beta}1$ (10 pM) for up to 10 days with TGF-${\beta}1$ supplementation every 2 days, and the proportion of transformed SMC in the cell line was measured using immunofluorescence assay for fibroblast surface antigen every 2 days. Results: MMP-3 expression was significantly lower in group I than in group II. TGF-${\beta}1$-stimulated adventitial fibroblasts in group I expressed less SM ${\alpha}$-actin, SM-MHC, and Ki-67 than in group II. SM-calponin expression was not different between the two groups. Presence of fibroblast was observed on immunofluorescence assay after more than 6 days of TGF-${\beta}1$ treatment in group I, while most fibroblasts were transformed to SMC within 4 days in group II. Conclusion: ECM production and SMC transformation are compromised in adventitial fibroblasts from patients with TAAD. This result suggests that functional restoration of adventitial fibroblasts could well be a novel approach for the prevention and treatment of TAAD.

• 한국생산제조학회지
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• 제8권4호
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• pp.19-28
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• 1999

In order to control thermal deformation of the machine origin of machine tools a empirical model and a compensation system have been developed, Prior to empirical modeling the volumetric error considering shape errors and joint errors of slides is formulated through the homogeneous transformation matrix (HTM) and kinematic chain. Simulation results of the HTM method show that the thermal error of the machine origin is more critical than position-dependent errors. In order to make a stable and effective software error compensation system the GMDH (Group Method of Data Handling) models are constructed to estimate the thermal deformation of the machine origin by measuring deformation data and temperature data. A test bar and gap sensors are used to measure the deformation data. In order to compensate the estimated error the work origin shift method is developed by implementing a digital I/O interface board between a CNC controller and an IBM PC. The method shifts the work origin as much as the amounts which are calculated by the pre-established thermal error model. The experiment results for a vertical machining center show that the thermal deformation of the machine origin is reduced within $\pm$5$mu extrm{m}$.

• 전력전자학회논문지
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• 제7권2호
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• pp.178-185
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• 2002

본 연구에서는 왜형되고 불평형인 전원의 정상분 순시전압 검출기법(Detection Method of Instantaneous Positive Sequence Voltage : PSD)에 의한 3상 3선 능동전력필터 시스템을 제작하였다. 불평형 및 왜형된 전원전압은 PSD에 의하여 정상분 순시전압을 실시간으로 검출한 후 순시전력이론의 상변환 행렬을 연산하고 있으며, 따라서 왜형되고 불평형된 전원조건에 순시전력이론을 적용하기 위하여 종전의 순시전력이론의 수학적인 구조를 변경할 필요가 없다. 본 연구에서 구현된 방법의 타당성을 입증하기 위해, 왜형된 B상 전압을 20% 증가시킨 전원과 불평형 비선형 부하 조건하에서 정상상태 및 과도상태의 실험을 수행하였으며, PSD가 없는 방법에 비하여 구현된 방법의 유용성을 입증할 수 있었다.

• Structural Engineering and Mechanics
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• 제14권6호
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• pp.679-698
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• 2002

In this paper some techniques for the dynamic analysis of non-classically damped linear systems are reviewed and compared. All these methods are based on a transformation of the governing equations using a basis of complex or real vectors. Complex and real vector bases are presented and compared. The complex vector basis is represented by the eigenvectors of the complex eigenproblem obtained considering the non-classical damping matrix of the system. The real vector basis is a set of Ritz vectors derived either as the undamped normal modes of vibration of the system, or by the load dependent vector algorithm (Lanczos vectors). In this latter case the vector basis includes the static correction concept. The rate of convergence of these bases, with reference to a parametric structural system subjected to a fixed spatial distribution of forces, is evaluated. To this aim two error norms are considered, the first based on the spatial distribution of the load and the second on the shear force at the base due to impulsive loading. It is shown that both error norms point out that the rate of convergence is strongly influenced by the spatial distribution of the applied forces.

• Journal of Power Electronics
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• 제14권1호
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• pp.92-104
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• 2014

To insure stable operation and eliminate twice torque ripple, a topology for a six phase permanent magnet synchronous generator (SP-PMSG) with a neutral point connected together was analyzed in this paper. By adopting an extended transformation matrix, the mathematic model of the space vector control was established. The voltage and torque equations were deduced while considering the third harmonic flux and inductance. In addition, the suppression third harmonic method and the closed loop control strategy were proposed. A comparison analysis indicates that the cooper loss minimum method and the current magnitude minimum method can meet different application requirements. The voltage compensation amount for each of the methods was deduced which also takes into account the third harmonic effect. A simulation and experimental result comparison validates the consistency through theoretical derivation. It can be seen that all of the two control strategies can meet the requirements of post-fault.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2004년도 ICCAS
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• pp.1958-1961
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• 2004

Ring Laser Gyroscopes used as navigational sensors inherently experience a lock-in region, where very low rotational rates are not measurable. Most RLG manufacturers use a mechanical dither motor that applies a small oscillatory rotational motion larger than this region to resolve this problem. Any input acceleration that bends this dithering axis causes flexure error, which is a noncommutative error that can not be compensated by simply using integrated gyro sensor output. This paper introduces noncommutative error equations that define attitude errors caused by flexure errors. In this paper, flexure error is classified as sensor level error if the sensing axis coincides with the dithering axis and as system level error if the two axes do not coincide. The relationship between gyro output and the rotation vector is introduced and is used to define the coordinate transformation matrix and angular motion. Equations are derived for both sensor level and system level flexure error analysis. These equations show that RLG based INS attitude error caused by flexure is directly proportional to time, amount of input acceleration and the dynamic frequency of the vehicle.

• 한국전산구조공학회논문집
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• 제12권3호
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• pp.397-406
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• 1999

본 연구는 부구조화에 기초한 다단계 혼성 구조 재해석방법을 제시한다. 부구조화의 틀에 보존근사화의 각 항을 차원축소법의 기저로 한 보존 전역-부분근사화에 의하여 변위 산정의 정확성과 효율성을 확보하고, 이를 바탕으로 이미 구성된 응력-변위 관계식을 병용하는 혼성방식을 통하여 전체 설계의 중간 단계에서 반복되는 재해석 과정의 신뢰성을 높인다. 전체적으로 선형근사화와 상반근사화를 교차적용하는 1단계 보존근사화로부터 전역 근사화와 결합하여 구하는 변위산정과 그에 종속되는 행렬연산으로 산출하는 응력계산의 3단계로 이루어지는 본 방법은 대형 구조계를 대상으로 하여, 해석의 기본 틀로 부구조화 방법을 택하였으며, 몇 개의 예제들을 통하여 타당성 및 유용성을 검증하였다.

• 한국CDE학회논문집
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• 제20권3호
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• pp.263-268
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• 2015

Due to an increased sitting time in work, lumbar disc disease is one of the most frequent diseases in modern days, and this occasionally requires surgery for treatment. Endoscopic disc surgery, one of the common disc surgeries, requires a process of inserting a guide needle to the target disc for which the insertion path is manually planned by drawing lines on the patient's skin while monitoring the fluoroscopic view of the lumbar. Such procedure inevitably exposes both surgeon and patient to the fluoroscopy radiation emitted from the c-arm for a long time. To reduce the radiation exposure time, this study proposes a computer assisted method of calculating the 3D guide needle path by using 2D c-arm images of the disc in 3 different angles. Additionally, a method of the guide robot control based on the 3D needle path was developed by implementing the Hand-eye Calibration method to calculate the transformation matrix between the c-arm and robot base coordinate systems. The proposed system was then tested for its accuracy.

• Steel and Composite Structures
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• 제25권3호
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• pp.315-326
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• 2017

In this work, thermoelastic dynamic behavior of functionally graded carbon nanotube reinforced composite (FG-CNTRC) cylinders subjected to mechanical pressure loads, uniform temperature environment or thermal gradient loads is investigated by a mesh-free method. The material properties and thermal stress wave propagation of the nanocomposite cylinders are derived after solving of the transient thermal equation and obtaining of the time history of temperature field of the cylinders. The nanocomposite cylinders are made of a polymer matrix and wavy single-walled carbon nanotubes (SWCNTs). The volume fraction of carbon nanotubes (CNTs) are assumed variable along the radial direction of the axisymmetric cylinder. Also, material properties of the polymer and CNT are assumed temperature-dependent and mechanical properties of the nanocomposite are estimated by a micro mechanical model in volume fraction form. In the mesh-free analysis, moving least squares shape functions are used to approximate temperature and displacement fields in the weak form of motion equation and transient thermal equation, respectively. Also, transformation method is used to impose their essential boundary conditions. Effects of waviness, volume fraction and distribution pattern of CNT, temperature of environment and direction of thermal gradient loads are investigated on the thermoelastic dynamic behavior of FG-CNTRC cylinders.

• 한국해양공학회지
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• 제21권4호
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• pp.45-54
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• 2007

In the context of auto-landing containers from a container ship to a truck or automatic guided vehicle and vice versa, this research investigates three schemes, one in Part I and two in Part II, for measuring the absolute position of a container. Coordinate transformations between the reference-coordinate, sensor-coordinate, and body-coordinate systems are briefly discussed. The scheme explored in Part I aims the use of three laser-slit sensors, which are relatively inexpensive. In this case, nine nonlinear equations are formulated for six unknown variables (three for orientation and three for position), so a closed-form solution is not available. Instead, an approximate solution through linearization was derived. An advantage of the method in Part I is its ability to measure an absolute position in 3D space, while a disadvantage is the computation time required to obtain pseudo-inverses and the approximate nature of the obtained solution. Numerical examples are provided.