• International Journal of Advanced Culture Technology
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• 제5권3호
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• pp.1-10
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• 2017

In this paper, we examine the points of similarity and difference between Korea, Japan, and the USA in terms of the spin-off effects of space technology on cultural life. In Japan and the USA, spin-off effects of space development research by government funded research centers are diffusive while in Korea they are interruptive. Spin-offs of research results impact cultural life via technology transfer and commercialization in businesses. This is because the Korean aerospace industry has progressed largely based on an overall system, but the promotion of internal parts and sub-systems, which can trigger technological development and spin-off effects in manufacturing, has been neglected. In the case of the KARI, the government funded research center, we argue that it is necessary for KARI to devote more resources to transfer (or promote spin-offs of) space technology to small and medium-sized businesses and other industries.

• Archives of Pharmacal Research
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• 제28권2호
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• pp.129-141
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• 2005

(-)-Fumagillol (1), a hydrolysis product of fumagillin, has been synthesized by several group from commercially available 1,2:5,6-di-O-isopropylidene-${\alpha}$-D-allofuranose in a highly stereoselective manner. Chiral centers on C5 and C6 came from D-allofuranose and the asymmetric center on C4 was accomplished by 1,3-chirality transfer using the Claisen rearrangement on a chiral allyl alcohol. Chirality, which is necessary on an epoxide consisting of the spiro-ring system, was diastereoselectively constructed by the well-known reaction, intramolecular ester enolate alkylation (IEEA), which showed that this reaction can be applied to the alpha-alkoxy ester system. The epoxide on the side chain was regioselectively introduced by the difference between the number of substituents on the vinyl groups. This accomplishment proved that IEEA can be a useful tool for the synthesis of complex molecules.

• 전기학회논문지
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• 제61권1호
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• pp.28-33
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• 2012

The smart grid, which is an integrated type of the power system and the digital network, requires the integration of a CIM(Common Information Model) standard for information modelling at the power control centers and an IEC 61850 standard for automation at the substation level in order to efficiently exchange the information between system elements. This paper describes the method of data transfer from one standard information model to the other standard unified information model by mapping between the objects of IEC 61850 and IEC61970 CIM standards both in the static and dynamic models, and designs the method of data transfer and information exchange between the topology processing application using unified topology class packages.

• 대한토목학회논문집
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• 제30권6D호
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• pp.561-567
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• 2010

현재 다수의 복합환승센터 건설 사업이 추진 중에 있으며, 이때 다수의 유사 사업에 대하여 한정된 투자재원으로 경제적 타당성 분석결과에 따라 투자우선순위를 결정하는 것이 타당한 방법이나, 계량화되지 않는 정책적 사항 등에 대한 고려도 충분히 반영할 필요가 있다. 이에 본 연구는 환승체계 개선을 위한 복합환승센터의 정량적인 지표인 경제성분석과 파급효과 등 정량적 지표와 사업추진의지, 재원조달가능성, 지역의 낙후도 등 정성적인 지표를 결합하여 복합환승센터의 우선순위 평가 방법론을 새로이 정립하였다. 제시된 평가방법을 적용하여 투자우선순위 평가 시 정량적 평가는 이용수요가 타 환승센터에 비해 많은 센터가 높게 평가되었다. 정성적 평가는 현재 사업이 추진되고 있는 복합환승센터에서 사업추진 가능성이 높은 센터에서 우선순위가 높게 평가되었다. 따라서 정량적 평가와 정성적 지표를 동시에 적용하여 분석한 결과 지역 간 형평성을 반영할 수 있었다.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1997년도 추계학술대회
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• pp.35-39
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• 1997

Recent development of human genetics and techniques of gene transfer and expression have opened the way for investigating novel approaches based on the genetic modification of cells to treat both inherited and acquired diseases. This approach is referred to as gene therapy. Over the past few years, gene therapy has moved from the laboratory to phase I clinical trials. Although the clinical performance of gene transfer experiments is still in an early phase of development, the NIH of Health Recombinant DNA Advisory Comittee (RAC) has approved more than 150 protocols that involve gene transfer or putative gene therapy procedures in clinical settings. Many sectors of society in United States have participated in the design and formulation of these clinical trials through local Institutional Review Boards, the National Institutes of Health (NIH) RAC, the Chemotherapy Evaluation Program of the National Cancer institute, and the FDA. Currently, clinical trials involving gene modification are under way at many medical centers throughout the United Slates. The goals of these trials are as follows. (1) The design should be directed to short-term achievable goals. (2) Each clinical trial is best considered as an intermediate step in a multistep process. (3) The design should identify evaluable proximate endpoints for toxicity and for efficacy, (4) The potential benefits and possible risks for patients participating in these trial should be defined.

• 대한원격탐사학회지
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• 제35권1호
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• pp.151-162
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• 2019

Surface temperature has been derived from the MODIS/ASTER airborne simulator (MASTER) mid-wave infrared single channel data using the MODerate resolution atmospheric TRANsmission (MODTRAN) radiative transfer model with input data including the University of Wisconsin (UW) emissivity, the National Centers for Environmental Prediction (NCEP) atmospheric profiles, and solar and line-of-sight geometry. We have selected the study area that covers some surface types such as water, sand, agricultural (vegetated) land, and clouds. Results of the current study show the reasonable geographical distribution of surface temperature over land and water similar to the pattern of the MASTER L2 surface temperature. The thorough quantitative validation of surface temperature retrieved from this study is somehow limited due to the lack of in-situ measurements. One point comparison at the Salton Sea buoy shows that the present estimate is 1.8 K higher than the field data. Further comparison with the MASTER L2 surface temperature over the study area reveals statistically good agreement with mean differences of 4.6 K between two estimates. We further analyze the surface temperature differences between two estimates and find primary factors to be emissivity and atmospheric correction.

• 전기학회논문지
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• 제61권12호
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• pp.1857-1863
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• 2012

The VDS(Vehicle Detection System) collects and transfers information about traffic situations in real time, therefore it makes the traffic management effective. Recently, the VDSs have provided good stability and accuracy in regard to system reliability and functions but they also have showed problems such as raising costs and consuming times when a new system is installed and/or the environmental requirements for the system are set up. The reason of the problems is that up to now the collection of the data and information about the traffic situations has been achieved by the 1:1 information exchange between the traffic control surveillance center and the each traffic field, between equipments and centers, and among data processing equipments and also centers. The communication systems used in the VDS are generally composed of 1 : 1 connection of the lines because the communication protocols are different in the most of the cases mentioned above. Consequently, this makes the number of communication lines become larger and causes the cost for the whole traffic information systems to increase. In this paper, a development of a controller to unify the communication protocols for the VDS is peformed to solve the problems which were mentioned above. Specially, the controller developed in this paper was applied to a radar vehicle detector and tested to show its usefulness. In addition to that, the developed controller was also designed to include functions to transfer the information about weather conditions on the roads.

• Bulletin of the Korean Chemical Society
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• 제19권6호
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• pp.654-660
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• 1998

$[Fe^{II}Fe^{III}BPLMP(OAc)_2](BPh_4)_2$ (1), a new model for the reduced form of the purple acid phosphatases, has been synthesized by using a dinucleating ligand, 2,6-bis[((2-pyridylmethyl)(6-methyl-2-pyridylmethyl)amino) methyl]-4-methylphenol (HBPLMP). Complex I has been characterized by X-ray diffraction method as having (μ-phenoxo)bis(acetato)diiron core. Complex 1 was crystallized in the monoclinic space group C2/c with the following cell parameters: a=41.620(6) Å, b=14.020(3) Å, c=27.007(4) Å, β=90.60(2)°, and Z=8. The iron centers in the complex 1 are ordered as indicated by the difference in the Fe-O bond lengths which match well with typical $Fe^{III}-O\; and\; Fe^{II}-O$ bond lengths. Complex 1 has been studied by electronic spectral, NMR, EPR, SQUID, and electochemical methods. Complex 1 exhibits strong bands at 592 nm, 1380 nm in $CH_3CN$ (ε = 1.0 × 103 , 3.0 × 102). These are assigned to $phenolate-to-Fe^{III}$ and intervalence charge-transfer transitions, respectively. Its NMR spectrum exhibits sharp isotropically shifted resonances, which number half of those expected for a valence-trapped species, indicating that electron transfer between $Fe^{II}\;and\;Fe^{III}$ centers is faster than NMR time scale. This complex undergoes quasireversible one-electron redox processes. The $Fe^{III}_2/Fe^{II}Fe^{III}\;and\;Fe^{II}Fe^{III}/Fe^{II}_2$ redox couples are at 0.655 and -0.085 V vs SCE, respectively. It has $K_{comp}=3.3{\times}10^{12}$ representing that BPLMP/bis(acetate) ligand combination stabilizes a mixed-valence $Fe^{II}Fe^{III}$ complex in the air. Complex 1 exhibits a broad EPR signal centered near g=1.55 which is a characteristic feature of the antiferromagnetically coupled high-spin $Fe^{II}Fe^{III}$ system $(S_{total}=1/2)$. This is consistent with the magnetic susceptibility study showing the weak antiferromagnetic coupling $(J= - 4.6\;cm^{-1},\; H= - 2JS_1{\cdot}S2)$ between $Fe^{II}\; and \;Fe^{III}$center.

• 한국항만경제학회지
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• 제34권2호
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• pp.31-50
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• 2018

본 연구는 공급사슬의 시각으로 항만배후단지 위험물 취급자를 대상으로 실시하는 교육훈련을 형성적 모델과 반영적 모델을 결합한 구조방정식을 통해서 실증분석을 하였다. 각 경로의 효과크기도 분석하였다. 실증분석 결과는 교육훈련환경과 교육분위기는 위험물 취급자의 교육기대에 정(+)의 영향을 미치고, 교육기대는 교육훈련프로그램과 교육훈련전이에 정(+)의 영향을 미친다. 교육훈련프로그램은 교육훈련전이와 교육훈련성과에 정(+)의 영향을 미친다. 교육훈련전이는 교육훈련성과에 정(+)의 영향을 미치며, 교육훈련 성과는 실제 위험물관리현황에 정(+)의 영향을 미친다고 검증되었다. 효과크기분석 결과를 보면, 교육분위기는 교육기대에, 교육기대는 교육훈련프로그램에, 교육훈련전이는 교육훈련성과에, 교육훈련성과는 위험물관리현황에 모두 큰 효과가 있다고 검증되었다. 본 연구결과는 지속가능한 항만배후단지 위험물 안전관리 프로세스를 조성하는 데 다양한 시사점을 제공할 것이다.

• Bulletin of the Korean Chemical Society
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• 제34권9호
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• pp.2577-2582
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• 2013

A novel stick-shaped portable sensing device featuring a microhole array interface between the polyvinylchloride-2-nitrophenyloctylether (PVC-NPOE) gel and water phase was developed for in-situ sensing of perchlorate ions in real water samples. Perchlorate sensitive sensing responses were obtained based on measuring the current changes with respect to the assisted transfer reaction of perchlorate ions by a perchlorate selective ligand namely, bis(dibenzoylmethanato)Ni(II) (Ni(DBM)2) across the polarized microhole array interface. Cyclic voltammetry was used to characterize the assisted transfer reaction of perchlorate ions by the $Ni(DBM)_2$ ligand when using the portable sensing device. The current response for the transfer of perchlorate anions by $Ni(DBM)_2$ across the micro-water/gel interface linearly increased as a function of the perchlorate ion concentration. The technique of differential pulse stripping voltammetry was also utilized to improve the sensitivity of the perchlorate anion detection down to 10 ppb. This was acquired by preconcentrating perchlorate anions in the gel layer by means of holding the ion transfer potential at 0 mV (vs. Ag/AgCl) for 30 s followed by stripping the complexed perchlorate ion with the ligand. The effect of various potential interfering anions on the perchlorate sensor was also investigated and showed an excellent selectivity over $Br^-$, $NO_2{^-}$, $NO_3{^-}$, $CO{_3}^{2^-}$, $CH_3COO^-$ and $SO{_4}^{2^-}$ ions. As a final demonstration, some regional water samples from the Sincheon river in Daegu city were analyzed and the data was verified with that of ion chromatography (IC) analysis from one of the Korean-certified water quality evaluation centers.