• 동의생리병리학회지
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• 제35권5호
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• pp.139-150
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• 2021

This paper examines whether the conceptual metaphor theory, which has been recently treated as important research topic in the field of cognitive linguistics, can be a new method that can promote the modernization of basic Korean medicine (KM) theory. In addition, the significance and potential of this study are reviewed by looking at Chinese research cases that applied this theory to Traditional Chinese Medicine theories and terminologies. The results are summarized as follows. From the viewpoint of metaphoric cognition, KM is a medicine that attempts to understand the human body (microcosm) through nature (great universe) by metaphorically projecting human experiences of nature on the human body based on the thought of correspondence between nature and human (天人相應). The language system of KM is based on a metaphor that extends our experience of nature to the human body, and an abundance of metaphors can be seen throughout the language of KM. Understanding and interpreting KM theories and terminologies from a metaphorical point of view allow us to understand the nature of KM theoretical key terms more deeply than now. And this understanding can help define and describe KM theoretical key terms and promote the modernization of KM theory research. In addition, various image schema that plays an important role in the metaphorical expansion of physical experience can be used for modeling KM theory. Research of KM theories and terminologies from a metaphorical point of view can serve as a bridge between traditional KM theory and modernization research, opening a new path to the modernization of basic KM theory in difficult situations.

• 대한암한의학회지
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• 제25권2호
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• pp.37-49
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• 2020

Objective: Constipation is the most common adverse effect of opioid analgesic therapy in cancer patients. This can be associated with physical and emotional distress to cancer patients. The purpose of this study is to review the standard and alternative interventions of the management for opioid-induced constipation (OIC). Methods: The studies were searched from databases, including Pubmed, Google scholar, KISS, NDSL, and OASIS. The main search terms included such as constipation, opioid, opioid-induced constipation, cancer, management, herb, and acupuncture. Results: The prevention and usual care of constipation is a key tool for the management of OIC. Also, prophylactic laxatives starting concurrently with opiates helped to prevent developing constipation. Peripherally acting μ-opioid receptor antagonists (PAMORAs) significantly reduced OIC and well-tolerated. In addition, acupuncture, herb medicines, and interferential current or transcutaneous electrical nerve stimulation to acupoints had effectiveness in reducing constipation. Conclusion: Preliminary data indicate that PAMORAs and Traditional Korean Medicine may be considered as the management of unresolved OIC. However, due to the limited articles, more systematic and rigorous clinical trials are needed.

• 대한한의학회지
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• 제33권3호
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• pp.46-53
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• 2012

Objectives: Many cancer patients have been using Korean medicine with conventional medical care. This study aimed to look into current status of Korean medicine in cancer patients in Korea. Methods: We reviewed utilization of Korean medicine for cancer by searching DB (KoreaMed, KMbase, KISS, NDSL, KISTI, National Assembly Library, OASIS, Korean Traditional Knowledge Portal). The first search keyword used was "cancer" and the second keyword used was either "oriental", "alternative" or "complementary". Results: The utilization rate of Korean medicine was 31.0%. In terms of patient's disease characteristics, most of them were suffering from stomach cancer, lung cancer and colon cancer. Most of them were diagnosed as fourth stage of cancer. Ginseng (14.8%) was a favorite Korean medicine, followed by medicinal treatment (8.1%), acupuncture (3.1%), moxibustion (3.0%), and cupping (2.1%). Conclusions: In Korea, one third of cancer patients are using Korean medicine. We need to know the expectations and demand for Korean medicine for treating cancer and establish our strategy to attract public attention.

• 대한한방내과학회지
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• 제36권2호
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• pp.85-92
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• 2015

Objectives: The liver fibroscan has been developed as a noninvasive and convenient method to assess hepatic fibrosis. This study aimed to review this device in terms of its technological concept and clinical application in traditional Korean medicine (TKM). Methods: The technological background, diagnostic evaluation, and clinical usefulness of fibroscan were reviewed using various literature and clinical studies. One clinical example-a patient with hepatofibrosis who had been treated with TKM-is presented. Results: The liver fibroscan was approved as a medical device for noninvasive measurement of the hepatic fibrosis level by the Korean Food and Drug Administration (KFDA). Numerous clinical studies have confirmed that its sensitivity and specificity allow it to serve as a substitute for liver biopsy, the present gold standard diagnostic method. The accuracy and reproducibility and lack of technical risks are strong points of the fibroscan; however, it has some limitations for application, especially in patients with obesity or severe hepatitis. One clinical example showed the applicability of the liver fibroscan in herbal medicine-based treatments. Conclusions: The requirement for diagnostic medical devices is an important issue in TKM; therefore, this study provides valuable information for practitioners of TKM.

• 동의생리병리학회지
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• 제27권5호
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• pp.540-552
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• 2013

This study focuses on discussing several issues that we encounter when we 'modernize' the fundamental theories of Korean Medicine(KM): It is pertinent to set the boundaries of the "fundamental theories" of the KM. The boundaries can be set based on: a) setting the medicine and the philosophy of medicine apart and b) re-evaluating the traditional theories of KM based on the needs of the modern practitioners of KM. The fundamental theories of KM should focus on how effectively they can observe, explain, and predict the clinical cases. The clinical cases and observations should not be distorted in order to satisfy the theory. "The modernization of KM" can be defined as the change in traditional medicine to fit the needs of the contemporary world, while not losing the focus and the nature of the KM. The fundamental theories of KM will play a key role in modernizing the KM, as the focus and the inherent nature of the KM comes from these fundamental theories. The modernization of the fundamental theories of KM will be crucial to both possible models of future healthcare system-the plural healthcare system, or the western medicine-centric integrated healthcare system. The modernization will also help in advancing the future medical studies. The key to modernization of the fundamental theories of the KM is in translating the key terms of KM in modern light. As a solution, this study suggests paying attention to the 'scientific metaphors', and especially to the 'theory-constitute metaphors' among those. More in-depth studies need to be done on these.

• 대한한방내과학회지
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• 제40권3호
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• pp.458-477
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• 2019

Objectives: This study aimed to investigate the trend in the research on alcoholic liver disease (ALD) using Korean traditional medicine. Methods: This review was conducted using six electronic databases (NDSL, KMBASE, Koreantk, KISS, KISTI, and KoreaMed) with no restrictions in year. The search terms were "alcoholic liver disease", "alcoholic fatty liver", "alcoholic hepatitis", "alcoholic cirrhosis", "herbal medicine", "acupuncture" and "traditional medicine". The searched studies were analyzed according to the type of research. Results: After screening, 37 studies were selected among 552. The types of studies were as follows: 8 in vivo studies, 17 case reports, 7 case series, 1 assessment scale study, 1 randomized controlled trial, and 3 research reviews. The in vivo studies reported the efficacy and its mechanism in the animal phase of single or complex herbal medicine. In the clinical research, interventions such as herbal medicine and acupuncture were most commonly used for ALD treatment. Conclusions: We analyzed the trends in ALD treatment using Korean traditional medicine through this review. The results showed that Korean traditional medicine could be an effective method for ALD treatment. Conducting related in-depth studies, such as well-designed randomized controlled trial based on the results of experimental research, is necessary.

• 동의신경정신과학회지
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• 제18권1호
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• pp.37-61
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• 2007

Objective : By examining EEG status in Korean Traditional Medicine (KTM) from the viewpoint of 'form-qi theory(形氣論)', We wish to prepare for the fundamentals of applicability of KTM diagnoses to EEG. In addition, through reinterpretation of existing Western Medicine reports from the viewpoint of KTM, We tried to find out interrelationship between them. Method : In this paper, a methodology applicable to KTM diagnoses of EEG is presented from the EEG features in waveform characteristics, personalized diversity, and cognitive activity reflection. Results : Frequency bands are assigned to corresponding one of the eight trigrams in terms of yin/yang balance, which is analogous with EEG spectrum analysis mostly used in EEG quantification. The amplitude ratio of each EEG for each frequency band gives meaningful index numbers which can be used in EEG data interpretation, and every index number is named after the sixty four hexagrams. These approaches are adopted through both '4-band classification system and '6-band classification system', and applied to pre-existing reported EEG data obtained from normal adults. These analyses show that changes and distribution pattern in the index numbers are observed as a whole on both left-right line and front-back line connecting EEG measurement cephalic electrodes. And differences in distribution pattern of three index numbers deduced from '6-band classification system' are discussed according to constitution. Conclusion : The index numbers introduced here, which are the spectral power ratio for each EEG, are based on KTM yin/yang balance. These index numbers vary according to cephalic location, so its application in terms of traditional meridian theory is strongly expected. The index number distribution also shows different patterns according to constitution.

• 동의생리병리학회지
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• 제30권4호
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• pp.219-228
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• 2016

The aim of this study was to collect and analyze the clinical studies of traditional herbal medicine and acupuncture treatments for colorectal cancer patients searched in Pubmed and Cochrane library in English. We collected the clinical studies, including randomized controlled trial, case control study and cohort study, in the PubMed and Cochrane library using keywords 'Colorectal Cancer', 'Korean Medicine', 'Traditional Chinese Medicine', 'Kampo' and 'Acupuncture'. Then we analyzed them according to the objective of the therapy, i.e. improving therapy prognosis, reducing chemotherapy's adverse event and reducing operational adverse event. In case RCT, we evaluate the quality of the study with jadad scale. Total 18 studies were selected. There were 3 studies about improving therapy prognosis, 6 studies about reducing chemotherapy's adverse event and 9 studies about reducing operational adverse event. Traditional medicine might improve therapy prognosis in terms of the survival rate, relapse/metastasis rate, quality of life and immune function. The specific herbal formula, 'Goshajinkigan' might not be successful about reducing chemotherapy's adverse event, peripheral neurotoxicity. 'Hangeshanshinto' might reduce the duration of oral mucositis but it is not clear to reduce the incidence of that. 'PHY906' might reduce the incidence of diarrhea. Acupuncture might reduce operational adverse event such as gastrointestinal dysfunction and pain. And 'Daikenchuto' might not be successful in reducing operational adverse event, gastrointestinal dysfunction. Further studies are needed to clarify the efficacy of traditional herbal medicine and acupuncture for colorectal cancer patients.

• Journal of Acupuncture Research
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• 제22권2호
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• pp.141-146
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• 2005

Objectives: To investigate the effect of Ginseng herbal acupuncture at GB39 and ST36 on growth in mice. Methods: Mice were divided into four groups (n=10); G-ST36 group treated with Ginseng Radix herbal acupuncture at right ST36, G-GB39 group treated with the same at GB39, Control-ST36 group and Control-GB39 group injected with saline at right ST36 and GB39 respectively. The saline injection and herbal acupuncture were performed 3 times a week for 3 weeks. The length( total height, body length and tail length), weight and the protein efficiency ratio were measured as well as IGF-I level in serum Results: The weights of Ginseng herbal acupuncture groups were not significantly increased compared to the control groups but the protein efficiency ratios were significantly higher in Ginseng herbal acupuncture groups compared to the control groups. The increases of the total length, body length and tail length were significantly higher in Ginseng herbal acupuncture groups than the control groups. The serum IGF-I level of G-GB39 was significantly increased compared to control-GB39, not that of G-ST36 compared to control-ST36. Conclusions: Ginseng herbal acupuncture at GB39 and ST36 are both effective to promote growth in terms of height and weight. GB39 may be effective for growth by way of increasing IGF-I, and more closely related to growth in height than ST36.

• 대한한의학회지
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• 제32권1호
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• pp.121-129
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• 2011

Objective: The propose of this study is to build a conceptual framework for representing clinical findings in Traditional East Asian Medicine(TEAM). As the existing standard models have been developed without considering features of Traditional Medicine, in this study we introduced unique characteristics for the TEAM. Method: This study was composed of three steps. First, we analyzed whether the existing clinical information models are suitable for representing clinical findings. Second, we analyzed ISO/TS 22789 model which is a ISO medical informatics standard, to find out the problem by applying clinical findings of TEAM into the model. Finally, we defined semantic links and a concept hierarchy in our model based on the analyzed results. The model includes the concepts for clinical findings and terms, and the semantic links can be regarded as relations between concepts, so that the representating clinical findings are completed by connecting concepts with other concepts. Results: Our framework was developed by removing unnecessary semantic links, and adding some necessary ones based on ISO/TS 22789 model. The ISO/TS 22789 model has a simple concept hierarchy, but in this study we subdivided the hierarchy and also considered interoperability with other terminological systems and standard models. Conclusions: This research needs more discussions, but is meaningful as proposing a way how to develop Traditional Medicine terminological systems. This study shows the limitations of existing models in describing clinical findings for TEAM, and what should be considered to represent Traditional Medicine knowledge, and propose a solution to improve the problem.