• Biomedical Science Letters
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• v.29 no.3
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• pp.103-108
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• 2023

Enhancers are cis-elements to regulate transcription of cell/tissue-specific genes in multicellular organisms. These elements locate in upstream or downstream regions of target genes and are found in a long distance up to 100 Kb in some cases. Transcription factors and coactivators bind to enhancers in a chromatin environment. Enhancers appear to facilitate the transcription of target genes by communicating with promoters and activating them. As transcription activation mechanism of enhancers, chromatin looping between enhancers and promoters, tracking of enhancer activity to promoters along the intervening regions, and movement of enhancers and promoters into transcription condensates have been suggested based on various molecular and cellular biology studies. These mechanisms are likely to act together rather than exclusive each other for gene transcription. Understanding of enhancer action mechanism may provide a way to regulate the transcription of cell/tissue-specific genes relating with aging or various diseases.

• International Journal of High-Rise Buildings
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• v.10 no.4
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• pp.265-283
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• 2021

To ensure that fire induced collapse of a building is prevented it is important to understand the sequence of events that can lead to this event. In this paper, the initiation of collapse mechanisms of generic a multi-storey steel frame subjected to vertical and horizontal travelling fires are analysed computationally by tracking the formation of plastic hinges in the frame and generation of fire induced loads. Both uniform and travelling fires are considered. In total 58 different cases are analysed using finite element software LS-DYNA. For the frame examined with a simple and generic structural arrangement and higher applied fire protection to the columns, the results indicate that collapse mechanisms for singe floor and multiple floor fires can be each split into two main groups. For single floor fires (taking place in the upper floors of the frame (Group S1)), collapse is initiated by the pull-in of external columns when heated beams in end bays go into catenary action. For single floor fires occurring on the lower floors(Group S2), failure is initiated (i.e. ultimate strain of the material is exceeded) after the local beam collapse. Failure in both groups for single floor fires is governed by the generation of high loads due to restrained thermal expansion and the loss of material strength. For multiple floor fires with a low number of fire floors (1 to 3) - Group M1, failure is dominated by the loss of material strength and collapse is mainly initiated by the pull-in of external columns. For the cases with a larger number of fire floors (5 to 10) - Group M2, failure is dominated by thermal expansion and collapse is mainly initiated by swaying of the frame to the side of fire origin. The results show that for the investigated frame initiation of collapse mechanisms are affected by the fire type, the number of fire floors, and the location of the fire floor. The findings of this study could be of use to designers of buildings when developing fire protection strategies for steel framed buildings where the potential for a multifloor fire exists.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2009.10a
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• pp.896-899
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• 2009

The fear of unauthorized, hidden readouts has dominated the radio frequency identification (RFID) privacy debate. Therefor all published and previous works for privacy mechanisms so far require consumers to actively and explicitly protect read access to their tagged items. This paper introduces the underlying mechanism of our extension to considerations for security and analyzes its tracking resistance and identification performance, and discusses deployment aspects.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37 no.5C
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• pp.355-364
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• 2012

Target processing mechanisms are necessary to collect target information, real-time data fusion, and tactical environment recognition for cooperative engagement ability. Among these mechanisms, the target tracking starts from predicting state of speed, acceleration, and location by using sensors' measurements. However, it can be a problem to give the reliability because the measurements have a certain uncertainty. Thus, a technique which uses multiple sensors is needed to detect the target and increase the reliability. Also, data fusion technique is necessary to process the data which is provided from heterogeneous sensors for target tracking. In this paper, a target tracking algorithm is proposed based on probabilistic data association(PDA) by fusing radar and ESM sensor measurements. The radar sensor's azimuth and range measurements and the ESM sensor's bearing-only measurement are associated by the measurement fusion method. After gating associated measurements, state estimation of the target is performed by PDA filter. The simulation results show that the proposed algorithm provides improved estimation under linear and circular target motions.

• Asia Marketing Journal
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• v.17 no.4
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• pp.21-42
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• 2016

Purpose: Social influence has a decisive role in shaping a person's cognition and behavior. Chinese face consciousness, including moral component, is an important part of Chinese traditional culture, which influences people to implement moral behavior. With both eye-tracking technology and traditional questionnaire, this research aims to explore people's moral psychology and the psychological processing mechanisms of Chinese face consciousness, as well as the impact of Chinese face consciousness on the preference for the ecological product. Method and Data: 75 college and MBA students' eye movement data were collected when they read different kinds of moral materials, as well as data from the subsequent questionnaires. To test the hypothesis, ANOVA analysis and Heat Map analysis were performed. Besides, the PROCESS of bootstrap was used to test mediation effect. Findings: The results reveal that: 1. Compared to the moral-situation reading, when subjects read immoral situations, they need more processing time due to the moral dissonance and cognitive load. 2. Compared to the control condition, when threatened moral self is primed, subjects prefer to choose ecological product. 3. Protective face orientation is the mediator between threatened moral self and preference to ecological product. Key Contributions: First, this study broadens the use of eye-tracking technology in marketing and demonstrates a better understanding of the relationship between morality and consumer behavior in a more scientific way. Second, this study not only distinguishes the meanings between "protective face orientation" and "acquisitive face orientation", but also innovatively validates that when moral self is threatened, consumers tend to choose ecological product as moral compensation in order to protect their face. It can shed light on the promotion of ecological product in practical applications.

• 제어로봇시스템학회:학술대회논문집
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• 2003.10a
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• pp.2648-2653
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• 2003

This paper describes the development of a 3-DOF laparoscopic assistant robot system with motor-controlled bending and zooming mechanisms using the voice command motion control and auto-tracking control. The system is designed with two major criteria: safety and adaptability. To satisfy the safety criteria we designed the robot with optimized range of motion. For adaptability, the robot is designed with compact size to minimize interference with the staffs in the operating room. The required external motions were replaced by the bending mechanism within the abdomen using flexible laparoscope. The zooming of the robot is achieved through in and out motion at the port where the laparoscope is inserted. The robot is attachable to the bedside using a conventional laparoscope holder with multiple DOF joints and is compact enough for hand-carry. The voice-controlled command input and auto-tracking control is expected to enhance the overall performance of the system while reducing the control load imposed on the surgeon during a laparoscopic surgery. The proposed system is expected to have sufficient safety features and an easy-to-use interface to enhance the overall performance of current laparoscopy.

• Genomics & Informatics
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• v.12 no.3
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• pp.98-104
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• 2014

Approximately 45% of the human genome is comprised of transposable elements (TEs). Results from the Human Genome Project have emphasized the biological importance of TEs. Many studies have revealed that TEs are not simply "junk" DNA, but rather, they play various roles in processes, including genome evolution, gene expression regulation, genetic instability, and cancer disposition. The effects of TE insertion in the genome varies from negligible to disease conditions. For the past two decades, many studies have shown that TEs are the causative factors of various genetic disorders and cancer. TEs are a subject of interest worldwide, not only in terms of their clinical aspects but also in basic research, such as evolutionary tracking. Although active TEs contribute to genetic instability and disease states, non-long terminal repeat transposons are well studied, and their roles in these processes have been confirmed. In this review, we will give an overview of the importance of TEs in studying genome evolution and genetic instability, and we suggest that further in-depth studies on the mechanisms related to these phenomena will be useful for both evolutionary tracking and clinical diagnostics.

• Journal of the Korean Institute of Intelligent Systems
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• v.14 no.5
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• pp.598-603
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• 2004

An optical head actuator of an optical disk drive consists of two servo mechanisms for the focusing and the tracking to acquire data from disk. As the rotational speed of the disk grows, the utilized lag-lead-lead compensator has known to be above its ability for precisely controlling the optical head actuator. To overcome the difficulty, this paper propose a new controller design method for optical head actuator based fuzzy proportional-integral-derivative (PID) control and the genetic algorithm(GA). It employs a two-stage control structure with a fuzzy PI and a fuzzy PD control and is optimized by the GA to yield the suboptimal fuzzy PID control performance. It is shown the feasibility of the proposed method through a numerical tracking actuator simulation.

• Advances in nano research
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• v.2 no.2
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• pp.77-88
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• 2014

Solvothermal treatment of late transition metal acetylacetonates in a novel medium composed either of pure acetophenone or acetophenone mixtures with amino alcohols offers a general approach to uniform hydrophilic metal nanoparticles with high crystallinity and low degree of aggregation. Both pure metal and mixed-metal particles can be accesses by this approach. The produced materials have been characterized by SEM-EDS, TEM, FTIR in the solid state and by Nanoparticle Tracking Analysis in solutions. The chemical mechanisms of the reactions producing nanoparticles has been followed by NMR. Carrying out the process in pure acetophenone produces palladium metal, copper metal with minor impurity of $Cu_2O$, and NiO. The synthesis starting from the mixtures of Pd and Ni acetylacetonates with up to 20 mol% of Pd, renders in minor yield the palladium-based metal alloy along with nickel oxide as the major phase. Even the synthesis starting from a mixed solution of $Cu(acac)_2$ and $Ni(acac)_2$ produces oxides as major products. The situation is improved when aminoalcohols such as 2-aminoethanol or 2-dimethylamino propanol are added to the synthesis medium. The particles in this case contain metallic elements and pairs of individual metals (not metal alloys) when produced from mixed precursor solutions in this case.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.12
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• pp.5422-5441
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• 2016

Despite the abundant literature in the field, there is still the need to find a time-efficient, highly accurate, easy to deploy and robust localization algorithm for real use. The algorithm only involves minimal human intervention. We propose an enhanced Received Signal Strength Indicator (RSSI) based positioning algorithm for Wi-Fi capable devices, called the Dynamic Weighted Evolution for Location Tracking (DWELT). Due to the multiple phenomena affecting the propagation of radio signals, RSSI measurements show fluctuations that hinder the utilization of straightforward positioning mechanisms from widely known propagation loss models. Instead, DWELT uses data processing of raw RSSI values and applies a weighted posterior-probabilistic evolution for quick convergence of localization and tracking. In this paper, we present the first implementation of DWELT, intended for 1D location (applicable to tunnels or corridors), and the first step towards a more generic implementation. Simulations and experiments show an accuracy of 1m in more than 81% of the cases, and less than 2m in the 95%.