• 동의생리병리학회지
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• 제19권5호
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• pp.1272-1280
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• 2005

The study was performed by examining the effects of fermented liquid of Crataegi Fructus on the lipid profile improvement in rats fed high fat diets. Sprague-Dawley rats of weighting $180.0{\pm}30g$ were randomly divided into five groups : basal diet (Normal control group, NCG), only high fat diet (High fat control group, HFC), high fat diet and supplemented with 1.69 mg/100 g body weight, 3.38 mg/100 g body weight, 6.76 mg/100 g body weight by fermented liquid of Crataegi Fructus - HFL, HFM, HFH group). These experimental diets were fed for 6 weeks. The fermented liquid of Crataegi Fructus fed groups had more significantly decreased in the levels of serum total cholesterol, triglyceride, LDL-cholesterol and atherogenic index than the high fat control group, while the HDL-cholesterol was higher when compared to the normal control group. Total lipid, total cholesterol, triglyceride, LDL-cholesterol contents in liver were decreased in high fat experimental groups. But the degree of increment was reduced by administration of fermented liquid of Crataegi Fructus. while the fermented liquid of Crataegi Fructus fed group had ore significantly increased in the level of HDL-cholesterol than the high fat control group. The singularity of the unsaturated fatty acid contents attracted our attention. Especially, the polyunsaturated fatty acid compositions were 36.36%, 34.70%, 20.31%in serum, liver and fecal of fermented liquid of Crataegi Fructus fed groups, respectively. These results imply that the fermented liquid of Crataegi Fructus can be used as possible food resources and medicinal food materials.

• Korean Chemical Engineering Research
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• 제45권1호
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• pp.73-80
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• 2007

본 연구는 생물학적 폐수 처리 공정인 연속 회분식 반응기(sequencing batch reactor, SBR)에서 질소 제거 최적화를 위해 활성 오니 공정모델(activated sludge model, ASM No.1, ASM1)과 반복 동적 프로그래밍(iterative dynamic programming, IDP)을 이용하여 SBR의 처리 기준을 만족하면서 최적 운전 조건을 탐색하고 하는 것을 목적으로 하였다. 연속 회분식 반응기의 최적화를 위해 에너지 최소화와 최소 회분 시간이 질소 처리의 농도 그래프의 면적과 비례하는 점을 이용하여 이를 고려한 새로운 performance index를 제안하였다. 회분 시간과 에너지에 대항하는 면적에 적절한 비중(weight)을 줌으로써 최소 회분 시간과 최소 에너지 문제를 동시에 고려하였다. SBR에서 IDP를 이용한 최적 운전서 최적 용존 산소 농도의 설정치가 전체 회분 시간과 전체 에너지 비용에 동시에 영향을 미침을 알 수 있었고 최적 운전시 기존의 운전 방법과 같은 유기물과 질소 제거가 가능하고 동시에 전체 비용을 20％까지 줄일 수 있었다. 더 나아가 공정이상으로 실제 공정이 모델과 다른 모델링 에러에 의해 잘못된 모사의 경우에도 IDP를 이용하여 다시 재최적화할 수 있음을 보였다.

• Restorative Dentistry and Endodontics
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• 제35권5호
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• pp.321-334
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• 2010

연구목적: 본 연구는 상아질 접착제의 잔류 용매가 접착 효율에 미치는 영향을 평가하고자 하였다. 연구 재료 및 방법: 본 연구에서는 5세대 2단계 산부식형 접착제와 7세대 단일과정 자가부식형 접착제를 사용하였다. 상아질 접착제의 증발률과 전환률, 적용 후 용매의 공기건조 방법에 따른 미세인장결합강도를 측정하였으며 접착 계면을 FE-SEM을 이용하여 관찰하였다. 결과: 1. 시간에 따라 접착제의 증발률은 증가하나 접착제의 종류에 따라 증가 양상이 서로 달랐다. 2. 대부분 전환률은 증발률에 비례하는 경향을 나타내었다. 3. 공기건조 방법에 따라 결합강도는 대부분 under군, control군, over군 순으로 증가하는 양상을 나타내었다. 4. FE-SEM에서 아세톤을 용매로 사용하는 접착제는 공기건조 방법에 따라 droplet이나 gap이 관찰되었다. 결론: 상아질 접착제의 잔류 용매는 접착 효율에 부정적인 영향을 미치기 때문에, 상아질 접착제의 선택과 사용 시 용매의 종류와 특징에 대한 적절한 이해가 필요할 것이다.

• Journal of Preventive Medicine and Public Health
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• 제53권6호
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• pp.476-486
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• 2020

Objectives: The objective of this study was to estimate the risk of lung cancer in relation to angiotensin II receptor blocker (ARB) use among patients with hypertension from the Korean National Health Insurance Service-National Health Screening Cohort. Methods: We conducted a retrospective cohort study of patients with hypertension who started to take antihypertensive medications and had a treatment period of at least 6 months. We calculated the weighted hazard ratios (HRs) and their 95% confidence intervals (CIs) of lung cancer associated with ARB use compared with calcium channel blocker (CCB) use using inverse probability treatment weighting. Results: Among a total of 60 469 subjects with a median follow-up time of 7.8 years, 476 cases of lung cancer were identified. ARB use had a protective effect on lung cancer compared with CCB use (HR, 0.75; 95% CI, 0.59 to 0.96). Consistent findings were found in analyses considering patients who changed or discontinued their medication (HR, 0.50; 95% CI, 0.32 to 0.77), as well as for women (HR, 0.56; 95% CI, 0.34 to 0.93), patients without chronic obstructive pulmonary disease (HR, 0.75; 95% CI, 0.56 to 1.00), never-smokers (HR, 0.64; 95% CI, 0.42 to 0.99), and non-drinkers (HR, 0.69; 95% CI, 0.49 to 0.97). In analyses with different comparison antihypertensive medications, the overall protective effects of ARBs on lung cancer risk remained consistent. Conclusions: The results of the present study suggest that ARBs could decrease the risk of lung cancer. More evidence is needed to establish the causal effect of ARBs on the incidence of lung cancer.

• 농업과학연구
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• 제38권2호
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• pp.325-330
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• 2011

In order to revive the ecological function of degraded rivers, a total restoration plan for riverbeds and riparians needs to be developed. Previous evaluations for rivers were mainly focused on the river's physical structures. Therefore, this research has developed indicators to evaluate a riparian restoration considering biodiversity. Through literature and previous cases review, 4 fields and 13 indicators are selected for the evaluation. Four fields are biodiversity, habitat diversity, connectivity and habitat functionality. In the biodiversity field, 4 indicators of the exuberant extent of herbaceous vegetation and their diversity, the exuberant extent of shrub and woody plants and their diversity, the number of plant communities and naturalized plants are included. Habitat diversity are comprised of 4 indicators of the longitudinal continuity of vegetation, the mixture of plant communities, the extent of plant type color fruit abundance and the distribution of vegetation. Connectivity includes 3 indicators of target distribution, the shore slope of low water channels and the extent of artificial embankment materials. Habitat functionality has 2 indicators of the status of food supply plants and the habitat functionality. The value weighting for the fields and indicators has been calculated based on the AHP(Analytic Hierarchy Process) method. 50 experts were surveyed with quantifiable questionnaire, among them 43 experts have more than 10 yesrs experiences in the nature restoration field. The selected and weighted indicators have been tested to the 12 sections in Gap stream located in Daejeon. In conclusion, the indicators are feasible and the selected indicators could be used to establish the direction and objectives of riparian restoration.

• 한국환경과학회지
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• 제6권6호
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• pp.563-578
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• 1997

The purpose of this study is to suggest the estimation model of' amenity environment' by Perceived Envionmental Quality Index(PEQI) model. A questionnaire survey was carried out for 연e study area of Taegu-Kyungbuk region. Sampling size was 838(427 of Taegu and 411 of Kyungbuk residents by stratified sampling of each region's(7 Gu for Tae-gu, 7 Cities 61 Gun far Kyungbuk) population. The survey was done during Sep. to Nov, of 1996. The suggested model was composed of four estimation categories and 16 Indicators. The four categories were 'Cleanness 61 Quietness', 'Naturalness & Harmony', 'Beauty 61 Comfort' and 'Environmental Conservation Efforts'. And each category has several individual Indicators. The weighted means of satisfaction were different by each region. Suseong-gu, Dalseogu, Joong-gu(Taegu), Bumcheon, Andong, and Cheondo(Kyungbuk) showed high enoronmental satisfaction, but Dong-gu. Seo-gu(taegu), Youngcheon, and Pohang(Kyungbuk) showed lower environmental satisfaction. By Analytic Hierarchy Process(AHP) of weighting values for each categorirs, 'Enoronmental Conservation Efforts' was estimated as the most Important(value of 0.367), and 'Naturalness 61 Harmony'(0. 242),'Clenness & guletness'(0.225), and 'Beauty & Comfort'(0.166) were Important respectively. Total PEQI's were estimated as 48.0 for Taegu, and 53.3 for Kyungbuk. PEQI's for each regions were between 46.2(Dong-gu) and 59.9(Kimcheon). The validity of the suggested model was verined by factor analysis. The four factors were identnied as the same categories and indicators. Finally, The LISREL+7 model was suggested as estimauon model of 'Amenity Environment' for Taegu-Kyungbuk region.

• 대한토목학회논문집
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• 제13권1호
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• pp.121-130
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• 1993

본 연구의 주요 목적은 댐 설계를 위한 유역의 비유사량 추정방법을 개발하는 것으로 유역면적 $200km^2{\sim}2,000km^2$ 정도의 중규모 유역을 대상으로 한다. 이를 위하여, 본 연구에서 개발할 비유사량 추정방법으로 통계적 방법에 의한 경험식과 미국 PSIAC 방법과 유사한 도표식 방법을 채택하였다. 이러한 방법들의 개발을 위해 본 연구에서는 과거 '60년대 이후 우리나라에서 수행된 하천유사량 실측자료 및 기존 다목적 및 발전댐 저수지 퇴사자료를 모두 수집 분석하여 비유사량 추정방법의 개발에 이용 가능한 자료 5 점을 도출하였다. 또한, 섬강, 금강상류, 내성천, 위천 등 4 개 조사유역의 8개 지점에서 하천유사량 자료를 실측하여 8개 지점에서의 연평균 비유사량을 산정하였다. 한편, 유역의 비유사량에 영향을 주는 유역특성 인자로 유역면적, 하천밀도, 강우 침식도, 식생 및 토지이용, 토양 침식성, 지형(기복 에너지), 하상재료 당 총 7 개의 유역특성인자를 선정하고, 각 인자의 정량화 방법을 제시하였다. 연구(II)에서는 이러한 유역특성 인자들과 중규모 유역에서 수집된 13 점의 이용가능한 유역 비유사량 자료를 이용하여 비유사량 추정방법을 개발한다.

• 한국초지조사료학회지
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• 제36권3호
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• pp.248-256
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• 2016

The present study investigated the effect of enzyme inclusion on silage quality using meta-analysis tool. A total of 16 research papers reporting the effect of enzyme application on silage quality were employed in the meta-analysis of this study. Mixed model for integrating quantitative results from multiple studies was used first to calculate the predicted error of each study. Individual error from the estimated model was the applied into standard deviation of each study to calculate the mean difference. Finally, summary effect was determined using standard mean difference (SMD) and inversed variance weighting. Mixed model analysis and SMD analysis showed the same effect patterns in all analysis items. Enzyme inclusion in silage significantly (p < 0.05) altered all silage quality characteristics investigated compared to control when enzyme was not included. Our results showed that enzyme treatment increased dry matter content, preserved crude protein effectively, and elevated water soluble carbohydrate content. However, the pH value, acetic acid, propionic acid, neutral detergent fiber, and acid detergent fiber contents in silage with enzyme inclusion were lower than those of the control.

• 보건행정학회지
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• 제9권1호
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• pp.156-177
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• 1999

The current method of rate adjustment for inflation is based on the evaluation of the financial performance of hospitals. The method has the disadvantage such as too complicated, expensive process as well as low reliability. This study, therefore, develops the 'Korean Medical Insurance Economic Index(MIEI)' as a new model for the rate adjustment with the use of the macro economic indices. In addition, we calculate the 1992∼1998 rate adjustment with the MIEI, and examines the validity of the MIEI by comparing with the conventional method. Medical costs are classified into nine categories : physician salaries, nurse·pharmacist·medical technician salaries, assistants & others salaries, material cost(by imports), material cost(by domestics), depreciation & rent paid(by imports), depreciation & rent paid(by domestics), power utilities, other administrative costs. Then the category weight which is the ratio of category in the total cost is calculated. Macro economic indices are selected for each cost category in order to reflect the concept of the each cost category and inflation during the year of 1992∼1998. Finally MIEI which integrate all category according to the category weight and selected macro indices is calculated. The mean of hospital MIEI which weighting by amount paid by insurers was cacluated. The result from the application of empirical data to the MIEI model is very similar to that of the current method. Furthermore, this method is very simple and also easy to get social consensus. This MIEI model can be replaced the current method based on the analysis of the financial performance for the adjustment of medical fees.

• Steel and Composite Structures
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• 제15권1호
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• pp.103-130
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• 2013

Fire performance and fire safety of high-rise buildings have become major concerns after the disasters of World Trade Center in the U.S. in 2001 and Windsor tower in Spain in 2005. Performance based design (PBD) approaches have been considered as a better method for fire resistance design of structures because it is capable of incorporating test results of most recent fire resistance technologies. However, there is a difficulty to evaluate fireproof performance of large structures, which have multiple structural members such as columns, slabs, and walls. The difficulty is mainly due to the limitation in the testing equipment, such as size of furnace that can be used to carry out fire tests with existing criteria like ISO 834, BS 476, and KS F 2257. In the present research, a large scale calorie meter (10 MW) was used to conduct three full scale fire tests on medical modular blocks. Average fire load of 13.99 $kg/m^2$ was used in the first test. In the second test, the weighting coefficient of 3.5 (the fire load of 50 $kg/m^2$) was used to simulate the worst fire scenario. The flashover of the medical modular block occurred at 62 minutes in the first test and 12 minutes in the second test. The heat resistance capacity of the external wall, the temperatures and deformations of the structural members satisfied the requirements of fire resistance performance of 90 minutes burning period. The total heat loads and the heat values for each test are calculated by theoretical equations. The duration of burning was predicted. The predicted results were compared with the test results, and they agree quite well.