• 한국수산과학회지
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• 제40권6호
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• pp.374-379
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• 2007

Two experiments were designed to examine short-term effects of human chorionic gonadotropin (hCG), and long-term effects of gonadotropin-releasing hormone agonist (GnRHa), $17{\alpha}-hydroxyprogesterone$ (17P), and $17{\alpha},20{\beta}-dihydroxy-4-pregnen-3-one\;(17,20{\beta}P)$, alone or in combination, on milt production of the starry flounder Platichthys stellatus. In the first experiment, fish were injected with either 200 IU hCG/kg body weight or the same volume of marine fish Ringer's solution (MFRS). In the second experiment, each fish was implanted with a blank cholesterol pellet (control), $200\;{\mu}g$ GnRHa, $500\;{\mu}g$ 17P, or $100\;{\mu}g\;17,20{\beta}P/kg$ body weight alone or in combination. In the first experiment, hCG injection resulted in an increase in the expressible milt volume and a decrease in the spermatocrit (Sct). After pellet implantation in the second experiment, the milt volume was increased in males treated with GnRHa, GnRHa+17P, or $GnRHa+17,20{\beta}P$. On day 7 after hormone pellet implantation, the milt volume began to increase, and on day 14, the milt volume in the $GnRHa+500\;{\mu}g$ 17P group was significantly higher than that in the control group. Compared with the control group, the hormone pellet-treated groups had a significant reduction in the mean Sct and sperm concentration (Sc) at day 7 after pellet implantation, while there were no differences in total sperm number. The results suggest that increases in milt volume are generally associated with decreases in Sct and SC, suggesting that the main mechanism for the increase in milt volume was milt hydration.

• 한국콘텐츠학회논문지
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• 제12권6호
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• pp.338-345
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• 2012

서구화된 식습관과 생활환경의 변화로 전립선비대증이 증가하고 있다. 하지만 진단 시 표준으로 참고할 기준이 되는 전립선 용적에 대한 연구가 부족하다. 또한 국내에서 이뤄진 연구의 대부분은 40대 이상의 중년 남성을 대상으로 하고 있다. 본 연구는 건강검진을 위해 방문한 30대 남성에서 경직장초음파로 측정한 전립선 용적을 후향적으로 분석하여 그 결과를 보고한 내용이다. 총 157명을 대상으로 하여 평균 연령은 $34.6{\pm}2.9$세이었고, 평균 전립선 용적은 $19.4{\pm}4.0ml$이었다. 전립선 용적은 연령, 전립선특이항원 수치, 체질량지수, 체표면적, 복부둘레와 양의 상관관계를 보였고, 특히 복부둘레와 가장 큰 상관관계를 보였다(r=0.317, p<0.001).

• 한국도로학회논문집
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• 제11권1호
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• pp.47-58
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• 2009

요금을 지불하게 되는 유료도로에 대해서는 별도의 가중치를 산정하여 교통계획 모형 내에서 모델링 할 수 있도록 해야 하나 현존하는 유료도로의 가중치 산정방법에서 발생하는 문제점은 현실과 유사한 통행패턴을 설명하기에 부적당하다. 본 연구는 국가교통DB센터에서 이미 정산된 가중치, 차종별 시간가치를 적용한 가중치 그리고 차로수별 교통량 비율로 수정된 가중치로서 총 세 개의 대안을 선정하여 비교 분석하였다. 그 결과 국가교통DB센터에서 정산되어 차로수의 구분없이 동일한 가중치를 적용하였을 경우에는 허용오차범위 내에 포함된 샘플수가 다른 시나리오에 비해 비교적 다수 포함되었으나 현재 유료도로의 차로수별 할인율과 할증률을 반영하지 않고 정산되었다는 점에서 현실에 맞지 않는 방법론으로 분석되었다. 또한 차종별 시간가치를 이용한 가중치는 현재 적용되는 가중치 중에서 가장 이론적으로 정립되었다고 할 수 있으나 가중치의 비율이 낮게 적용됨으로서 배정교통량이 과다예측 되는 결과로 나타났다. 그러나 차종별 시간가치와 차로수별 교통량 비율을 합산하여 재 산정한 가중치를 적용한 결과는 세 개의 대안 중 가장 현실에 근접한 통행배정 결과로 분석되었다. 또한 통행배정 방법에 있어 총량OD평형배정방법이 PCU통행배정방법보다 현실에 가까운 배정결과가 나타나는 것으로 나타났다.

• Journal of Preventive Medicine and Public Health
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• 제39권1호
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• pp.13-20
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• 2006

Objectives: To propose a risk-adjustment model with using insurance claims data and to analyze whether or not the outcomes of non-emergent and isolated coronary artery bypass graft surgery (CABG) differed between the low- and high-volume hospitals for the patients who are at different levels of surgical risk. Methods: This is a cross-sectional study that used the 2002 data of the national health insurance claims. The study data set included the patient level data as well as all the ICD-10 diagnosis and procedure codes that were recorded in the claims. The patient's biological, admission and comorbidity information were used in the risk-adjustment model. The risk factors were adjusted with the logistic regression model. The subjects were classified into five groups based on the predicted surgical risk: minimal (<0.5%), low (0.5% to 2%), moderate (2% to 5%), high (5% to 20%), and severe (=20%). The differences between the low- and high-volume hospitals were assessed in each of the five risk groups. Results: The final risk-adjustment model consisted of ten risk factors and these factors were found to have statistically significant effects on patient mortality. The C-statistic (0.83) and Hosmer-Lemeshow test ($x^2=6.92$, p=0.55) showed that the model's performance was good. A total of 30 low-volume hospitals (971 patients) and 4 high-volume hospitals (1,087 patients) were identified. Significant differences for the in-hospital mortality were found between the low- and high-volume hospitals for the high (21.6% vs. 7.2%, p=0.00) and severe (44.4% vs. 11.8%, p=0.00) risk patient groups. Conclusions: Good model performance showed that insurance claims data can be used for comparing hospital mortality after adjusting for the patients' risk. Negative correlation was existed between surgery volume and in-hospital mortality. However, only patients in high and severe risk groups had such a relationship.

• The Journal of Advanced Prosthodontics
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• 제14권3호
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• pp.173-181
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• 2022

PURPOSE. This analysis aimed to evaluate the intaglio surface trueness, antagonist's wear volume loss, and fracture resistance of full-contour crowns of (Y, Nb)-stabilized fully-sintered zirconia (FSZ), 4 mol% or 5 mol% yttria-stabilized partially sintered zirconia (4YZ or 5YZ) with high-speed sintering. MATERIALS AND METHODS. A total of 42 zirconia crowns were separated into three groups: FSZ, 4YZ, and 5YZ (n = 14). The intaglio surface trueness of the crowns was evaluated at the inner surface, occlusal, margin, and axial areas and reported as root-mean-square, positive and negative average deviation. Half of the specimens were aged for 120,000 cycles in the chewing simulator, and the wear volume loss of antagonist was measured. Before and after chewing, the fracture load was measured for each group. The trueness values were analyzed with Welch's ANOVA, and the wear volume loss with the Kruskal-Wallis tests. Effect of the zirconia type and aging on fracture resistance of crowns was tested using two-way ANOVA. RESULTS. The intaglio surface trueness measured at four different areas of the crown was less than 50 ㎛, regardless of the type of zirconia. No significant P in wear volume loss of antagonists were detected among the groups (P > .05). Both the type of zirconia and aging showed statistically significant effects on fracture resistance (P < .05). CONCLUSION. The full-contour crowns of FSZ as well as 4YZ or 5YZ with high-speed sintering were clinically acceptable, in terms of intaglio surface trueness, antagonist's wear volume loss, and fracture resistance after simulated mastication.

• 대한토목학회논문집
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• 제28권2D호
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• pp.155-162
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• 2008

본 연구에서는 전체 시간대별 교통량을 관측하지 못하여 설계시간교통량을 구할 수 없는 지점에 대하여 설계시간계수를 추정하는 방법에 대하여 분석하였다. 수시조사는 연 1~5회 조사되며, 이러한 지점에서는 설계시간교통량을 구할 수 없어 설계시간계수를 구할 수 없다. 분석을 위하여 2006년 일반국도 상시조사 지점의 시간대별 교통량을 이용하여 분석하였다. 설계시간계수를 추정하기 위하여 시간대별 교통량의 변동을 반영하는 시간대별 교통량의 변동계수(Coefficient of Variance), 시간대별 교통량의 표준편차, 첨두시간교통량(peak hour volume)과 도로의 특성을 파악할 수 있는 중차량비율, 주야율, AADT와 중방향계수 등의 변수를 독립변수로 하여 각 변수들과 설계시간계수와의 상관분석 및 회귀분석을 이용하여 설계시간교통량을 추정하였다. 산점도를 통하여 독립변수와 종속변수의 관계를 분석한 결과 대부분의 변수들이 곡선의 형태를 띠는 것으로 나타나 선형회귀분석보다 곡선회귀분석이 더 적합한 것으로 나타났다. 곡선회귀분석으로 분석한 결과 AADT를 독립변수로 하여 분석한 대수모형이 결정계수가 가장 높은 것으로 나타났다.

• Korean Journal of Radiology
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• 제21권4호
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• pp.450-461
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• 2020

Objective: We performed a meta-analysis to evaluate the agreement of cardiac computed tomography (CT) with cardiac magnetic resonance imaging (CMRI) in the assessment of right ventricle (RV) volume and functional parameters. Materials and Methods: PubMed, EMBASE, and Cochrane library were systematically searched for studies that compared CT with CMRI as the reference standard for measurement of the following RV parameters: end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), or ejection fraction (EF). Meta-analytic methods were utilized to determine the pooled weighted bias, limits of agreement (LOA), and correlation coefficient (r) between CT and CMRI. Heterogeneity was also assessed. Subgroup analyses were performed based on the probable factors affecting measurement of RV volume: CT contrast protocol, number of CT slices, CT reconstruction interval, CT volumetry, and segmentation methods. Results: A total of 766 patients from 20 studies were included. Pooled bias and LOA were 3.1 mL (-5.7 to 11.8 mL), 3.6 mL (-4.0 to 11.2 mL), -0.4 mL (5.7 to 5.0 mL), and -1.8% (-5.7 to 2.2%) for EDV, ESV, SV, and EF, respectively. Pooled correlation coefficients were very strong for the RV parameters (r = 0.87-0.93). Heterogeneity was observed in the studies (I² > 50%, p < 0.1). In the subgroup analysis, an RV-dedicated contrast protocol, ≥ 64 CT slices, CT volumetry with the Simpson's method, and inclusion of the papillary muscle and trabeculation had a lower pooled bias and narrower LOA. Conclusion: Cardiac CT accurately measures RV volume and function, with an acceptable range of bias and LOA and strong correlation with CMRI findings. The RV-dedicated CT contrast protocol, ≥ 64 CT slices, and use of the same CT volumetry method as CMRI can improve agreement with CMRI.

• International Journal of Fluid Machinery and Systems
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• 제3권1호
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• pp.29-38
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• 2010

This paper presents a procedure for the design optimization of a centrifugal compressor. The centrifugal compressor consists of a centrifugal impeller, vaneless diffuser and volute. And, optimization techniques based on the radial basis neural network method are used to optimize the impeller of a centrifugal compressor. The Latin-hypercube sampling of design-of-experiments is used to generate the thirty design points within design spaces. Three-dimensional Reynolds-averaged Navier-Stokes equations with the shear stress transport turbulence model are discretized by using finite volume approximations and solved on hexahedral grids to evaluate the objective function of the total-to-total pressure ratio. Four variables defining the impeller hub and shroud contours are selected as design variables in this optimization. The results of optimization show that the total-to-total pressure ratio of the optimized shape at the design flow coefficient is enhanced by 2.46% and the total-to-total pressure ratios at the off-design points are also improved significantly by the design optimization.

• Asian-Australasian Journal of Animal Sciences
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• 제18권1호
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• pp.96-101
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• 2005

There were two trials involved in the experiment. Trial 1: the trial was conducted on two Taiwan Sugar Corporation (TSC) pig farms. One was located in the north of Taiwan and the other was located in the south. Both farms had wet pad and forced ventilation (WPFV) and conventional open design (COD) boar and sow houses. There were 12 Duroc boars, age ranging from 12-24 months. Half of them (6 boars) were raised in a WPFV pig house, and the other half were kept in a COD house. Semen was collected at 5-day intervals from May $1^{st}$ to the end of October. Sixteen sows (2-8 parity) were served by artificial insemination each week from the beginning of May to the end of Oct. These sows were checked for heat from 18 days to 25 days after insemination. Trial 2: there were four MPFV boar houses involved in the test. Two houses were located in the north of Taiwan, and the other two houses were located in the south. The test was conducted from January 2000 to December 2001. The total number of serviced sows by MPFV-housed boars was 35,105 head and for COD-housed boars 103,065 head. The results showed that the total semen volume, density of sperm, total sperm per ejaculate, sperm motility and morphological abnormality were significantly better (p<0.01) for boar raised in WPFV house than for COD houses. Average sperm motility in June and July was lower than for the other months. Morphological abnormality was higher during May, June and July. Although the results did not reach a significant level, the average value showed that the total volume of boar semen was higher in the north than for the south. The total semen volume production of boar raised in WPFV was higher than for boars raised in COD house, reaching a significant level only in summer. Boars kept in WPFV house had higher total sperm number than boars kept in COD house, reaching a significant level in spring (p<0.05), summer (p<0.01), and fall (p<0.05) but not in winter (p>0.05). Boars raised in WPFV house had significantly higher sperm motility than boars in COD house during spring (p<0.001), summer (p<0.001), fall (p<0.01) and winter (p<0.05). The average farrowing rate and piglets born alive were higher for boars in WPFV house than for boars in COD house, but neither reached a significant level (p>0.05). The present experiment shows that WPFV house can improve the reproduction performance of boars.

• 한국대기환경학회지
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• 제22권2호
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• pp.249-257
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• 2006

In this work, the adsorptive and desorptive behavior of reduced sulfur compounds (RSC) was investigated using the combination of the Peltier cooling (PC)/thermal desorption (TD) unit with the gas chromatographic (GC) detection technique. To examine the adsorptive characteristics of RSC on clothing materials, a total of nine experiments were conducted in a stepwise manner. Once small towel pieces are exposed to significant quantities of RSC standards with high concentrations (10 ppm), the desoprtion stage was then induced by deloading RSC with ultrapure $N_2$ at three different flow rates (FR) of 20, 40, and 60 mL/min. At each FR, the total deloading volume of 400, 800, and 1,600 mL were maintained. These results were then compared in terms of odoring efficiency by dividing the total amount of desorption with the total amount used for exposition or RSC loading. The results indicated that desorption reaction of certain compounds ($CH_3SH$ and DMS) can be influenced significantly with the reducing FR, while they are not affected directly by the total deloading volume. In addition, when the extent of adsorption was compared for most S compounds by the odoring efficiency term, the extent of absorption generally occurred at approximately 1/1000 level of original exposition.