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Anticancer Activity of Acacia nilotica (L.) Wild. Ex. Delile Subsp. indica Against Dalton's Ascitic Lymphoma Induced Solid and Ascitic Tumor Model

  • Sakthive, K.M.;Kannan, N.;Angeline, A.;Guruvayoorappan, C.
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.3989-3995
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    • 2012
  • The aim of the present investigation was to evaluate the effect of A.nilotica extract against Dalton's ascitic lymphoma (DAL) induced solid and ascitic tumors in BALB/c mice. Experimental animals received A.nilotica extract (10 mg/kg.bw) intraperitoneally for 10 and 14 consecutive days before induction of solid and ascitic tumors, respectively. Treatment with A.nilotica extract significantly decreased the development of tumor and percentage increase in body weight when compared to DAL induced solid tumor control group, also increasing the life span, restoring the total white blood cell count and hemoglobin content and significantly decreasing the levels of serum aspartate transaminase (SGPT), alanine transaminase (SGOT), alkaline phosphatase (ALP), gamma glutamyl transferase (GGT) and nitric oxide (NO) when compared to DAL induced ascitic tumor controls. The treatment also reduced significantly the cellular glutathione (GSH) and nitric oxide levels in treated animals. Histopathological studies also confirmed protective influence. The outcome of the present work indicates that A.nilotica extract could be used as natural anticancer agent for human health.

Comparison of the Performance of Chamber and Bag Digesters for Solid State Anaerobic Digestion of Separated Solid Fraction of Swine Manure

  • Lee, Jaehee;Lee, Seunghun;Kim, Eunjong;Jo, Hyunsoo;Ahn, Heekwon
    • Korean Journal of Soil Science and Fertilizer
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    • v.48 no.2
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    • pp.94-99
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    • 2015
  • The performance of chamber and bag digesters for solid state anaerobic digestion (SS-AD) of separated solid fraction of swine manure was investigated using lab-scale digester (4,460 mL total volume and 1,800 mL of effective volume) operating at $37^{\circ}C$ for 63 days. The performance of two different digester types was evaluated in terms of the kinetic constants of methane production obtained from the Gompertz and Gaussian equations. Methane production potential of chamber and bag digester was 202 and $218N{\cdot}mL$ $CH_4/g$ VS. Time to produce 95% methane production potential (T95) and calculated effective anaerobic digestion time were 55.5 days and 41.8 days for chamber digester and 52.8 days and 43.5 days for bag digester, respectively. Our results reveal that the performance was not significantly different between chamber and bag digester.

Effect of Reaction Factors on Reducing Sugar Production from Enteromorpha intestinalis Using Solid Acid Catalyst (고체 산촉매를 이용한 창자파래로부터 환원당 생산에 미치는 인자들의 영향)

  • Jeong, Gwi-Taek;Park, Don-Hee
    • Korean Chemical Engineering Research
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    • v.53 no.4
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    • pp.478-481
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    • 2015
  • In this study, the hydrolysis of green macro-algae Enteromorpha intestinalis using solid acid catalyst was conducted to obtain total reducing sugar. The hydrolysis was optimized with four reaction parameters of liquid-to-solid (L/S) ratio, catalyst amount, reaction temperature, and reaction time. As a optimized result, the highest TRS of 7.74 g/L was obtained under condition of 7.5 L/S ratio, $140^{\circ}C$, 15% catalyst amount and 2 hr. By the way, at this condition, only 0.13 g/L 5-HMF was detected. The solid acid-catalyzed hydrolysis of marine resources had the potential in the field of bioenergy.

The Bioenergy Conversion Characteristics of Feedlot Manure Discharging from Beef Cattle Barn

  • Oh, Seung-Yong;Kim, Chang-Hyun;Yoon, Young-Man
    • Korean Journal of Soil Science and Fertilizer
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    • v.48 no.6
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    • pp.697-704
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    • 2015
  • This study was carried out to assess bioenergy conversion efficiency by biogas and solid fuel production in the cattle feedlot manure discharged from beef cattle barn. Feedlot manure was sampled from the cattle farmhouse located in Yong-in, Gyeonggi during the mid-fattening stage, periodically. The chemical characteristics, BMP (Biochemical methane potential) and HV (Heating values) of feedlot cattle manures were analyzed. Total solid contents of cattle feedlot manure were in the range of 29.98~44.28%, and volatile solid contents were in the range of 23.53~24.47%. In the anaerobic digestion of cattle feedlot manure, the methane production potential has increased from 0.141 to $0.187Nm^3kg^{-1}-VS_{added}$. The methane production of fresh cattle feedlot manure showed the range $0.141{\sim}0.187Nm^3kg^{-1}$-Manure (average $0.047Nm^3kg^{-1}$-Manure), the LHVs (lower heating values) of the produced methane were in the range of $316{\sim}560kcalkg^{-1}$-Manure (average $400kcalkg^{-1}$-Manure). In the direct combustion of fresh cattle feedlot manure, the LHVs were measured in the range of $747{\sim}1,271kcalkg^{-1}$-Manure (average $916kcalkg^{-1}$-Manure), and LHVs of solid fuel which have the water content of 20% were in the range of $2,694{\sim}2,876kcalkg^{-1}$-Manure (average $2,791kcalkg^{-1}$-Manure). Then, the drying energy of average $443kcalkg^{-1}$-Manure was consumed in the production of solid fuel which has a water content of 20%. Therefore, the direct combustion of cattle feedlot manure showed about 2.3 times higher LHV than the LHV of methane produced by anaerobic digestion. And LHV of solid fuel was about 6.0 times higher than the LHV of methane produced by anaerobic digestion. Then, the production of solid fuel presented more bioenergy conversion efficiency than the biogas production in the bioenergy use of cattle feedlot manure.

Impact of Screw Type on Kyphotic Deformity Correction after Spine Fracture Fixation: Cannulated versus Solid Pedicle Screw

  • Arbash, Mahmood Ali;Parambathkandi, Ashik Mohsin;Baco, Abdul Moeen;Alhammoud, Abduljabbar
    • Asian Spine Journal
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    • v.12 no.6
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    • pp.1053-1059
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    • 2018
  • Study Design: Retrospective review. Purpose: To detect the effect of cannulated (poly-axial head) and solid (mono-axial head) screws on the local kyphotic angle, vertebral body height, and superior and inferior angles between the screw and the rod in the surgical management of thoracolumbar fractures. Overview of Literature: Biomechanics studies showed that the ultimate load, yield strength, and cycles to failure were significantly lower with cannulated (poly-axial head) pedicle comparing to solid core (mono-axial head). Methods: The medical charts of patients with thoracolumbar fractures who underwent pedicle screw fixation with cannulated or solid pedicle screws were retrospectively reviewed; the subjects were followed up from January 2011 to December 2015. Results: Total 178 patients (average age, $36.1{\pm}12.4years$; men, 142 [84.3%]; women, 28 [15.7%]) with thoracolumbar fractures who underwent surgery and were followed up at Hamad Medical Corporation were classified, based on the screw type as those with cannulated screws and those with solid screws. The most commonly affected level was L1, followed by L2 and D12. Surgical correction of the local kyphotic angle was significantly different in the groups; however, there was no significant difference in the loss of correction of the local kyphotic angle of the groups. Surgical correction of the reduction in the vertebral body height showed statistical significance, while the average loss of correction in the reduction of the vertebral body height was not significantly different. The measurement of the angles made by the screws on the rods was not significantly different between the cannulated (poly-axial head) and solid (mono-axial head) screw groups. Conclusions: Solid screws were superior in terms of providing increased correction of the kyphotic angle and height of the fractured vertebra than the cannulated screws; however, no difference was noted between the screws in the maintenance of the superior and inferior angles of the screw with the rod.

Optimization of ultrasound-assisted extraction of anthocyanins and phenolic compounds from campbell early grape using response surface methodology (반응표면분석법을 이용한 캠벨얼리 포도의 총 안토시아닌과 총 페놀의 초음파 추출조건 최적화)

  • Ryu, Dayeon;Koh, Eunmi
    • Korean Journal of Food Science and Technology
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    • v.50 no.5
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    • pp.474-479
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    • 2018
  • In this study, ultrasound-assisted extraction conditions of total anthocyanins and total phenolic compounds from Campbell early grape (Vitis labruscana) were optimized via response surface methodology using a Box-Behnken design. Three independent variables, including solid-liquid ratio (1/30-1/50 g/mL), extraction time (2-10 min), and amplitude (20-100%), significantly affected total anthocyanin content. However, no significant effect of these variables was observed in the total phenolic compound content. The optimized extraction conditions were solid-liquid ratio of 1/48.13 g/mL, extraction time of 2 min, and amplitude of 20%. Under these conditions, the predicted values of total anthocyanins and total phenolic compounds were 94.96 and 1,661.16 mg/100 g dry weight (DW), respectively. The experimental values of total anthocyanins and total phenolic compounds were 88.25 and 1,554.37 mg/100 g DW, respectively, which is well matched with the predicted values within 7.5% difference.

FEM Analysis of a 38 Person Elevator Brake (38인승 승강기 제동장치의 유한요소해석)

  • Lee, Jong-Sun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.11
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    • pp.6458-6463
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    • 2014
  • This study performed FEM analysis of a 38 person elevator brake. Recently, an emergency brake was newly developed to improve elevator safety. A 3D design was developed using Solid Works and FEM analysis using analysis code ANSYS. The total deformation, stress and strain were obtained.

Uncertainty Analysis and Compensation of the Cell for Permittivity Measurement of Solid Materials (고체재료의 유전율 측정용 Cell의 불확도 분석과 보상)

  • Kim, Han-Jun;Yu, Kwang-Min;Kang, Jeon-Hong;Han, Sang-Ok
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.21 no.1
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    • pp.53-56
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    • 2008
  • The commercial parallel plate electrodes system with guard-ring electrode have been widely used for measurement of dielectric constants of solid materials. And the specification of the electrodes system is about 1 % of measurement uncertainty. This measurement uncertainty is only estimated the error come from mechanical measurements such as the area of the electrodes and the gap between the electrodes except the error come from the air gap between the electrodes and dielectric specimen. Because it is impossible to measure the air gap. This study analyze the total measurement uncertainties of the commercial dielectric constant test cell using 3 kinds of Standard Reference Materials. As a results, the total measurement uncertainty is much bigger than 1 % and the most of the uncertainty can be reduced by compensation of the error values evaluated in this study.

Effect of Steaming Prior to Roasting of Polygonatum odoratum Roots on Its Water Solubles and Browning (볶음전 증자처리가 둥굴레 근경의 수용성 성분 및 갈색화에 미치는 영향)

  • 권중호;임종호
    • Food Science and Preservation
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    • v.4 no.2
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    • pp.155-162
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    • 1997
  • This work was designed to determine the effect of steaming-Pretreatment on Physicochemical and functional properties of roasted Polygonatum odoratum roots. Steaming treatments led to some reduction in the contents of water solubles, such as total solid, reducing sugar and free-amino nitrogen of the unroasted samples. Moreover, roasting processing caused decrease in reducing sugar and free-amino acid, with increase in total soluble solid and browning color of the samples, which showed the dependence of steaming treatment as well as roasting temperature. Electron-donating ability and nitrite-scavenging ratio of the samples were also highly developed along with roasting processing at 17$0^{\circ}C$ within 35min. Considering the physicochemical and some functional parameters of water extracts of roasted samples, roasting at above 14$0^{\circ}C$ for over 55min or at 17$0^{\circ}C$ for around 35min was recommendable for the higher quality of Polygonatum odoritum tea, which conditions were similarly adapted for both steamed and unsteamed samples.

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Size dependent effect on deflection and buckling analyses of porous nanocomposite plate based on nonlocal strain gradient theory

  • Khazaei, Pegah;Mohammadimehr, Mehdi
    • Structural Engineering and Mechanics
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    • v.76 no.1
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    • pp.27-56
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    • 2020
  • In this paper, the deflection and buckling analyses of porous nano-composite piezoelectric plate reinforced by carbon nanotube (CNT) are studied. The equations of equilibrium using energy method are derived from principle of minimum total potential energy. In the research, the non-local strain gradient theory is employed to consider size dependent effect for porous nanocomposite piezoelectric plate. The effects of material length scale parameter, Eringen's nonlocal parameter, porosity coefficient and aspect ratio on the deflection and critical buckling load are investigated. The results indicate that the effect of porosity coefficient on the increase of the deflection and critical buckling load is greatly higher than the other parameters effect, and size effect including nonlocal parameter and the material length scale parameter have a lower effect on the deflection increase with respect to the porosity coefficient, respectively and vice versa for critical buckling load. Porous nanocomposites are used in various engineering fields such as aerospace, medical industries and water refinery.