• Korean Journal of Adult Nursing
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• v.14 no.3
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• pp.411-417
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• 2002

Purpose: This study was to investigate symptom occurrence related to the disease characteristics of patients with cancer. Method: A total of 301 patients with cancer participated in this study. The participants were recruited from University Hospitals located in Seoul, Wonju, Kwangju, Daegu, and Pusan. Data collection was performed by using a questionnaire on symptom occurrence. The obtained data was analyzed using SPSS computer program that included descriptive statistics, Pearson correlation, one-way ANOVA, and t-test. Result: The mean score of fatigue was the highest (3.24), followed by loss of appetite, lack of concentration, change in appearance, pain, insomnia, change in bowel pattern, nausea/vomiting, coughing, and dyspnea. Most symptoms were significantly correlated with each other. The level of symptom occurrence in patients with lung cancer or cervix cancer was significantly higher than the level in patients with stomach cancer. Patients receiving radiation therapy or a combined therapy of radiation therapy and chemotherapy experienced significantly higher level of symptom occurrence than those receiving chemotherapy only. Also, female patients experienced higher level of symptom occurrence than male patients did. Conclusion: The sites of cancer, types of treatment, and gender influence the level of symptom occurrence of patients with cancer. Thus, these variables should be considered when assessing and planing for symptom occurrence of patients with cancer.

• Journal of Oriental Neuropsychiatry
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• v.19 no.3
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• pp.143-169
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• 2008

Objective: This study was to investigate the relation of what insomnia patients' symptoms with Heart Rate Variability(HRV), Pittsburgh Sleep Quality Index (PSQI) and Insomnia Questionaire(IQ). Methods: For this study, we carried out HRV, PSQI and IQ of 43 patients with insomnia who have come to Donguei oriental hospital of Donguei university from September 2007 to May 2008. We studied the relationship HRV with PSQI and IQ. For every symptom, this study classified the patients as none-symptom, symptom groups and analyzed each group's HRV, PSQI and IQ. Result : 1. The rate of xerostomia in female group is significantly higher than male group. 2. P1 (hypnagogic time), P3(awakening time), LF has negative correlation with age. The score of PI (hypnagogic time), P3(awakening time), P4(time of recoverable sleep) in the group whose age is more than 50 are higher than the group whose age is lesser than 50. 3. The frequency of using hypnotics(P6) in the group whose duration of onset are over 1 year was significantly higher than the score in the group whose duration of onset were below 1 year. 4. The accompanied symptoms in the group who started sleep disorder after stressor are higher than the number in the group whose duration of onset were poor-defined. 5. The drinking group have lower rate of anorexia, higher score of P1 (hypnagogic time) and TP than non-drinking group. 6. The score of P-total(general quality of sleep) have negative correlation with NNSO, HF, TP and positive correlation with LF/HF. 7. The score of P1(hypnagogic time) have negative correlation with LF. 8. The score of P5a(frequency of delayed hypnagogue) have positive correlation with LF/HF. 9. The score of P5e(frequency of cough or snoring) have negative correlation with RMSSD. 10. The score of I1a(degree of onset insomnia), I1b(degree of maintenance insomnia) have negative correlation with NN50, pNN50, HF. 11. The score of I1c(degree of termination insomnia) have negative correlation with RMSSD, NN50, pNN50, HF, TP and positive correlation with MHR, LF/HF. 12.. The score of P5i(frequency of night pain), LF/HF in the group with headache are higher than the group without headache. 13. The score of P5a(frequency of delayed hypnagogue), P5c(frequency of awakening for urine of stool) in the group with xerostomia are higher than the group without xerostomia. 14. The score of P9(degree of unrecoverable sleep) and I5a(degree of onset insomnia) in the group with chest discomfort are lower than the group without chest discomfort. 15. The score of P7(frequency of drowsiness for daytime) in the group with palpitation are lower than the group without palpitation. 16. The score of P5c(frequency of awakening for urine of stool), P5f(frequency of burning sensation), P5h(frequency of nightmare), I1c(degree of termination insomnia) in the group with burning sensation of upper trunk are higher than the group without burning sensation. 17. The score of NN50, pNN50, LF, TP in the group with anorexia are lower than the group without anorexia. 18. The score of P-total(general quality of sleep), P2(duration for sleep start) in the group with constipation are higher than the group without constipation. 19. The score of P4(recoverable sleep time) in the group with depression are higher than the group without depression. 20. In the group with anxiety, the score of P1(time of hypnagogue), P5a(frequency of onset insomnia) are lower and the score of I1b(degree of maintenance insomnia), I4(objective degree of impairment by insomnia) are higher than the group without anxiety. 21. The score of NN50, pNN50, HF, TP in the group with inertia are lower than the group without inertia. 22. The accompanied symptoms haver posirive correlation with P5f(frequency of burning sensation), P5h(frequency of nightmare), P5i(frequency of night pain) and LF/HF. Conclusion: This study provides insights into the complicated relations of the pattern of sleep disorder with many symptoms such as headache, chest discomfort, depression and any others. And this study showed that autonomic nervous system have important function in the regulation of sleep.

• Korean Journal of Psychosomatic Medicine
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• v.8 no.2
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• pp.172-180
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• 2000

Objectives : We investigated the characteristics of perceived stress response and relationship between some variables of gastrointestinal symptoms(esp., dyspepsia) and subscales of perceived stress response inventory(PSRI) in patients with upper gastointestinal disorder when they perceived stress. Methods : 84 patients with upper gastrointestinal disorder(gastritis, gastric ulcer, duodenal ulcer etc.) and 94 normal controls completed the PSRI developed by Korean psychiatrists. The patient group performed the questionnaire including some variables of gastrointestinal symptoms. Results : Internal consistency was statistically significant in all subscales of PSRI. The patient group was significantly higher at total score of PSRI, general somatic symptom subscale score, specific somatic symptom score than control group. As the result of stepwise regression analysis for relationship between some variables of gastrointestinal symptoms ans subscales of PSRI, specific somatic symptom subsclae closely related with illness duration, past illness history and severity of symptom, and the lowered cognitive function & general negative thinking subscale related with the existence of emotional distress. Conclusion : Patients with upper gastrointestinal disorder showed stronger perceived stress response than control group and they experiences somatic symptoms related to autonomic nervous system and/or gastrointestinal symtoms rather than emotional, cognitive, behavioral symtoms when they perceived stress. They also responded to stress as they expeirenced specific somatic symtom when they had long illness duration, past illness history, and high severity of symptom and the existence of emotional distress could develop lowered congnitive function and general negative thinking.

• Journal of East-West Nursing Research
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• v.13 no.2
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• pp.170-178
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• 2007

Purpose: This study was to examine the effects of the Danjeon Breathing Exercise Program on physical fitness, levels of serum lipid and physical symptom of people using public health center at Yangju city. Method: One group pretest-posttest design was utilized for this study. This study has been done from July 6 to September 28, 2005 and the subjects of the study were 28 persons. Danjeon breathing exercise was carried out for 60 minutes a day, 3 times a week for 12 weeks. Physical fitness was measured using the Health Management System developed by the Korea Physical Science Institution. Serum lipid level was measured in public health center at Yangju city. Questions of physical symptom (35 items) were chosen from Cornell Medical Index. The collected data were processed by using the SPSS PC program and analyzed by using Wilcoxon Signed Rank Test. Result: 1. The scores of back strength, flexibility and balance of post-test were more increased after Danjeon breathing exercise than those of pre-test. But the score of muscular endurance of post-test was not significantly increased. 2. The degrees of total cholesterol, LDL-cholesterol and triglyceride of post-test were more decreased after Danjeon breathing exercise than those of pre-test. But the degree of HDL-cholesterol of post-test was not significantly increased in statistics. 3. The score of physical symptoms of post-test was not significantly decreased in statistics after Danjeon breathing exercise than that of pre-test. Conclusion: It is concluded that the Danjeon Breathing Exercise Program could increase the physical fitness and decrease levels of serum lipid. So Danjeon breathing exercise could be utilized to promote physical fittness and to decrease level of serun lipids.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.4
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• pp.95-104
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• 2011

Objectives: The purpose of this study is to investigate the relationship between the degree of menopausal symptom and granulocyte/lymphocyte ratio, and heart rate varibility(HRV). Methods: From 11th April 2011 to 20th May 2011, a total 30 female subjects (age 41-60) was recruited. We evaluated the degree of menopausal symptoms by Kupperman' s index and measured subject's WBC differential count and HRV. The data were analyzed by Kruskal-Wallis test and Spearman correlation test using SPSS/PC ver 13.0 program. Results: 1. There was no statistically significant difference in granulocyte/lymphocyte ratio and HRV among 4 classified groups according to Kupperman's index.- Mild, Moderate, Severe and Urgent. 2. Granulocyte ratio and general symptom score(within Kupperman's index) significantly showed negative correlation coefficient(r=-0.499, p=0.005), and Lymphocyte ratio and general symptom score significantly showed positive correlation coefficient (r=0.374, p=0.042). 3. Granulocyte/lymphocyte ratio and HRV showed no significant correlation. Conclusions: There was no significant relation among the degree of menopausal symptoms and granulocyte/lymphocyte ratio, and HRV. But furthermore large scale study is required.

• Mood & Emotion
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• v.9 no.2
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• pp.78-86
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• 2011

Objectives : The aim of this study was to investigate relationship between perceived stress level, cognitive emotion regulation (CER) strategy and hope in group with high depressive symptom and higher-level perceived stress (H-H) and group with high depressive symptom and lower-level perceived stress (H-L) in patients with depression. Method : A total of 85 patients (over score of 16 by Beck depression Inventory; BDI) were surveyed with Cognitive emotion regulation questionnaire (CERQ), Perceived stress scale (PSS), and The state hope scale (SHS). Mean scores of CERQ and SHS were compared between relatively higher perceived stress and lower perceived stress groups. Correlation analysis and multiple linear regression analyses were performed to identify the effect of BDI, PSS and CER strategy on SHS in two groups. Results : In ANOVA, the level of hope and maladaptive CERQ score proved to be significantly lower among the H-H group than among the H-L group, while adaptive CERQ scores were not. In Regression analysis, the effective CER strategy in SHS were 'Refocus on planning' in H-H group, while it was 'Acceptance' CER strategy in H-L group. The final regression model explained 36% of the variance of SHS in H-H group and explained 21% of SHS in H-L group. Conclusion : These findings suggest that 'Refocus on planning' and 'Acceptance' cognitive emotion strategy are helpful in promotion of state hope on depression. Especially, 'Refocus on planning' strategy is more effective in high depressive symptom and high-perceived stress level, while 'Acceptance' strategy help to promote hope in high depressive symptom and low-perceived stress level in patients with depression.

• Journal of Korean Public Health Nursing
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• v.14 no.1
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• pp.41-60
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• 2000

This study was designed and undertaken to identify the related factors of family caregivers' depression & quality of life with stroke elderly patient. The data was collected from August 16th to September 5th. 1999. The subjects in this study were 70 caregivers and 70 patients with stroke who were hospitalized in 2 oriental medicine hospitals and 3 hospitals located in Junla-buk do. The data was analized using percentage. means. t-test. ANOVA and pearson's correlation coefficients, step-wise multiple regression done with the SAS program. The results of this study are as follows; 1. The score for family caregivers' depression was 45.2 when total score was 80. The family caregivers who got more than 50 scores belongs to highly depression group amount to $29\%$. 2. The score for family caregivers' quality of life was 37.04 when total score was 56. 3. In the significant relationship between family caregivers' depression and general characteristics of the family caregivers ; age. sex, income. In the significant relationship between family caregivers' quality of life and general characteristics of family caregivers: age, education, income. In the significant relationship between family caregivers' depression and quality of life and general characteristics of stroke elderly patient ; sex. 4. The depression degree showed significant differences in the variables of family caregiver's physical health(r=-0.307, p=0.011), stress(r=0.463. p=0.011). social support (r=-0.241. p=0.046) and elderly stroke patient's ADL(r=-0.313, p=0.009). The quality of life degree showed significant differences in the variables of family caregivers' depression(r=-0.564, p=0.001), stress(r=-0.322, p=0.008), social support (r=0.353. p=0.003). 5. The most important variable affecting family caregiver's depression was caregivers' physical symptom which accounted for $32.0\%$ of the total variance in which multiple regression analysis. Total variance affecting the family caregivers' depression was $49\%$. The most important variable affecting family caregivers' quality of life was caregivers' depression which accounted for $48\%$ of the total variance in which multiple regression analysis. Total variance affecting the family caregivers' quality of life was $61\%$.

• Journal of the Korean Society of Physical Medicine
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• v.8 no.2
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• pp.183-192
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• 2013

PURPOSE: The purpose of this study was to research the effect of self-Stretching Exercise on musculoskeletal Symptom and job Stress for care helpers who work at geriatric hospital and come up to NIOSH standard. METHODS: The effect of self-Stretching Exercise was measured using 'musculoskeletal symptom survey table' and 'Job stress measurement scale for korean' from the Korea Occupational Safety and Health Agency(KOSHA) for 40 care helpers. The paired t-test and independent t-test was used for statistical analysis. RESULTS: The pracitce of Self-Stretching Exercise was showed significant effect reducing the stress for care helper's total job Stress and inappropriate compensation, job instability, job requirement, relationship conflict, physical environment(p<.05), and significant difference for their total score, relationship conflict, structure and organization, physical environment, inappropriate compensation improvement on variations on job stress in groups(p<.05). However, self-Stretching Exercis was showed no significant effect on physcial burden. CONCLUSION: The self-Stretching Exercise was the most effect way to reduce Musculoskeletal Symptom and job Stress for a care helpers through the guidance of physical therapist.

• The Journal of Internal Korean Medicine
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• v.44 no.4
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• pp.675-702
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• 2023

Objective: This study assessed the effectiveness of using Yijung-tang to treat chronic gastritis through a systematic review and meta-analysis of randomized controlled trials (RCTs). Methods: The search was conducted using keywords such as "gastritis", "Lizhong", "Yijung", and "Chronic gastritis" on July 31, 2023. A meta-analysis was conducted according to outcome measurements, such as total effective rate (TER), Traditional chinese medicine symptom score (TSS), gastric hormones, and symptom relief time, using the Review Manager website. Results: A total of 11 RCT studies were selected. The treatment group (Yijung-tang-gagam or Yijung-tang-gagam+Western medicine) showed significant improvement effects in terms of TER, TSS, serum gastrointestinal hormones (motilin (MTL), gastrin (GAS), and somatostatin (SS)), and symptom relief time compared to the control group (Western medicine). TER-RR : 1.20, 95% CI : 1.11 to 1.30, P≤0.00001, RR : 1.21, 95% CI : 1.14 to 1.28, P≤0.00001; MTL-MD : 35.99, 95% CI : 30.79 to 41.20, P≤0.00001); GAS-MD : 103.33, 95% CI : 97.62 to 109.04, P≤0.00001); SS : MD : -37.19, 95% CI : -41.75 to -32.64, P≤0.00001; symptom relief time (nausea)-MD : -1.96, 95% CI : -2.47 to -1.45, P≤0.00001; symptom relief time (colic)-MD : -1.75, 95% CI : -2.31 to -1.18, P≤0.00001. Conclusion: This study suggests that Yijung-tang is effective against chronic gastritis. However, the number of studies was insufficient, and the diagnosis and evaluation criteria were not standardized. Furthermore, because of the low quality of the included studies, more clinical studies need to be conducted to increase the possibility of clinical use.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.8
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• pp.4571-4576
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• 2013

Background: Depression is a comorbid disabling problem and potentially affects patient likelihood of survival. The aims of this study were to recognize the characteristics of depression and investigate associated predictor factors in patients with oral cancers. Methods: A cross-sectional and correlational design was used to collect data for this study conducted in northern Taiwan. A set of questionnaires was used to measure depression, symptom distress, performance status, social support, and demographic and disease-related information. Logistic regression was conducted to determine important factors predicting depression. Results: A total of 132 oral cancer patients participated in this study. Of these, 18.2% were identified as depression cases. The patient average performance status score was 90 or higher. Patients reported mild-to-moderate levels of symptom distress. The majority of social support was from families. Religious belief, alcohol use, symptom distress, and social support from family were found to be important factors predicting depression. Patients with religious belief with alcohol use reported greater symptom distress, and those with lower levels of social support from families were significantly more likely to develop depression. Conclusions: Clinicians should assess patient emotional status and manage symptoms in a timely manner to enhance coping abilities. Supportive care provides assurance during the acute survivor phase.