• 여성건강간호학회지
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• 제2권2호
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• pp.270-283
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• 1996

This study was done for the purpose of analyzing the relationship between menopausal symptoms and depression. Data were collected by a questionnaire from November 28 to December 30, 1995. The subjects were 134 women between 40-61 years of age. The instruments used for this study were The Menopausal symptom scale by Neugartom and Depression scale by Zung. The results of the study were as follows. 1. Mean score of menopausal symptoms was 1.59. Mean score orders of experienced symptoms were "Rack pain and joint pain"(2.02), "General weakness"(1.98), "Nervousness"(1.96). The most serious menopausal symptom was psychosomatic symptom.(1.88) Total score orders of experienced symptoms was 27.9 and over 90.3% of women complained menopausal symptom. 2. Mean score orders of depression was 39.13. It was normal range of depression. 85.1% of the women were normal range of depression and 14.2% of women mild depression. 3. The relationship between menopausal symptoms and depression was statistically significant(r=0.5307, p=0.000). When the relationship among three dimensions of menopausal symptoms were explored the psychosomatic symptom(r=0.4090, P=0.000), Physical symptom(r=0.319, P=0.000), Physical symptom(r=0.319, P=0.000) were statistically significant. 4. General characteristic variables were significantly related to the level of menopausal symptoms as follows ; environment of living(F=2.89, p=0.038), religion(F=4.18, P=0.007), times of birth(F=2.66, p=0.043). The analysis of this study have implication for management of middle aged women's health, to solve the nursing problems, and to prevent and relieve climacteric symptoms.

• 대한한방내과학회지
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• 제25권2호
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• pp.224-237
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• 2004

Background & Object : It is well known that functional dyspepsia is one of the most common diseases. While many dyspepsia patients have been helped with oriental medical therapy, there has not been a study based on the concepts of oriental medicine. The aim of this study was to perform a fundamental epidemiological survey and to analyse the symptom pattern of functional dyspepsia. Methods : 86 patients(27 males, 59 females) diagnosed with functional dyspepsia in Kyunghee Oriental Medical Center from May to December 2002 were involved in this investigation. The disease characteristics of functional dyspepsia(based on Rome criteria II) and the Qui Xue Shui diagnostic procedure were investigated by questionnaire and physical examination. The total score and composition ratio of each comprehensive diagnosis were calculated from the symptom score described in the questionnaire. Results : The total score from the Qui Xue Shui diagnostic procedure was found to be influenced by the number of functional dyspepsia symptoms(p=0.026) and the patient's own cognition of their current dyspeptic situation(p=0.006), in addition to digestive ability and general congnition(p=0.006), and was not associated with sex, duration of dyspeptic symptoms in one year, or the total illness period, In the composition ratio of the Qui Xue Shui diagnostic procedure, only Qui-yu(p=0.048) diagnosis was accurate regarding the number of symptoms in one year, total illness period, or the patients' own congnition of their current dyspeptic situation, But the value of the composition ratio among the total factors involved was most similar to that of sex. Conclusions : Thus, it is shown here that the total score of using the Qui Xue Shui diagnostic procedure is mainly dependent on dyspeptic symptoms and the patinets' own cognition of their current dyspeptic situation, and that regular symptom patterns in the Qui Xue Shui diagnostic procedure exist in dyspeptic patients.

• 사상체질의학회지
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• 제33권1호
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• pp.57-89
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• 2021

Objectives This study is aimed to develop a standard instrument of diagnosis and assessment for the original symptom of Taeeumin. Methods 1. Based on the clinical practice guidelines, the works of Dong-mu, and the expert clinical judgment of the research team, the items to be used in the instrument of diagnosis and assessment for the original symptom of Taeeumin were extracted, and translation was proceeded in plain Korean for easy application and feasible use in daily clinical practice. As a result, candidate items for the diagnosis and assessment tool were derived. 2. An online questionnaire survey was conducted on the candidate items derived through the above process to the expert advisory group for (1) inclusion/exclusion as diagnosis and assessment index (2) evaluation of importance and (3) the validity of translation. Results & Conclusions Through survey of expert advisory group, the number of candidate items were reduced and the preliminary weights were assigned. And based on this, was developed. There were a total of 9 items for Exterior Cold[Wiwanhan] original symptom diagnosis and assessment tool, 21 items for Interior Heat[Ganyeol] original symptom, 15 items for Exterior Disease Unfavorable Patterns[Wiwanhan-paejo] original symptom, and 17 items for Interior Disease Unfavorable Patterns[Ganyeol-paejo] original symptom, and the weights were reflected in each response score so that the final total score could be calculated.

• 여성건강간호학회지
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• 제7권2호
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• pp.157-168
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• 2001

The purpose of this study was to investigate of the relationship of the urinary incontinence, menopausal symptom and life satisfaction in middle aged women. The subjects of this study were 235 middle aged women, living in M city, during the period from June 21 to August 31, 2000. The instruments for this study were the urinary incontinence modified and adding by Lee Young Sook(1994), the menopausal symptom developed by Song Ae Ri and Chung Eun Soon(1998) and the life satisfaction translated and modified by Suh Kyung Hee(1988). Collected data were analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation coefficients and stepwise multiple regression with SAS package. The result of this are as follows : 1. The total mean score of urinary incontinence was $1.56{\pm}0.58$ with a range of 0 to 4. The mean score on the menopausal symptom was $2.05{\pm}0.43$ with a range of 1 to 4. The mean life satisfaction score was $1.14{\pm}0.41$ with a range of 0 to 2. 2.General characteristics ralated to urinary incontinence were age and numbers of children (F=7.66, p=0.000, F=2.86, p=0.037). General characteristics ralated to menopausal symptom were age (F=7.37, p=0.000), occupation (t=5.33, p=0.021), problem of children (t=6.46, p=0.011) and marital satisfaction (F=5.65, p=0.004). General characteristics ralated to life satisfaction were type of housing (t=12.06, p=0.000), problem of children (t=6.96, p=0.008) and marital satisfaction (F=18.86, p=0.000). 3.The urinary incontinence and menopausal symptom were correlated positively (r=.235, p=.000). The urinary incontinence and life satisfaction were correlated negatively (r=-.114, p=.007). The menopausal symptom and life satisfaction were correlated negatively (r=-.277, p=.000). 4.The menopausal symptom, type of housing and marital satisfaction explained 16.6% of the variance for life satisfaction in the middle aged women.

• 생물정신의학
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• 제20권2호
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• pp.40-44
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• 2013

Objectives The purpose of this study was to examine the differences according to depressive symptom-related difficulty status. Methods 2828 participants were a divided into depressive symptom-related difficulty group (difficult group, n = 774), and a non-depressive symptom-related difficulty group (not difficult group, n = 2054). The psychological character of the participants were assessed using the Korean version of the Patient Health Questionnaire-9 (PHQ-9), Satisfaction with Life Scale (SWLS), the 12-item General Health Questionnaire (GHQ-12), and Conner-Davidson Resilience Scale (CD-RISC). Statistical analyses were done using t-test, chi-square, and analysis of covariance (ANCOVA). Results Compared with the no difficulty group, the difficulty group reported significantly higher score in all items of PHQ-9. The score of "feeling tired" was the highest and the score of "suicidal ideation" is the lowest in both groups. ANCOVA analysis that is adjusted with the total score of PHQ-9 showed the differences in SWLS, GHQ-12, and CD-RISC scores between the difficulty group and the no difficulty group. Conclusions The findings suggest that there are different characters on PHQ-9, SWLS, GHQ-12, and CD-RISC according to depressive symptom-related difficulty. Therefore, it is required not only to evaluate depressive symptoms in patients with depression, but also the depressive symptom-related difficulty to understand these differences.

• Allergy, Asthma & Immunology Research
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• 제10권6호
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• pp.675-685
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• 2018

Purpose: This study aims to determine the efficacy and safety of house dust mite (HDM)-sublingual immunotherapy (SLIT) in elderly patients with AR. Methods: A total of 45 patients aged ${\geq}60years$ with HDM-induced AR who had ${\geq}3$ A/H ratio on skin prick test and/or ${\geq}0.35IU/L$ to both Dermatophagoides farinae and Dermatophagoides pteronyssinus by ImmunoCAP were enrolled in 4 university hospitals. To evaluate additional effects of HDM-SLIT, they were randomized to the SLIT-treated group (n = 30) or control group (n = 15). Rhinoconjunctivitis total symptom score (RTSS), rhinoscopy score, Korean rhinoconjunctivitis quality of life questionnaire, rhinitis control assessment test, asthma control test scores, and adverse reactions, were assessed at the first visit (V1) and after 1 year of treatment (V5); for immunological evaluation, serum levels of HDM-specific immunoglobulin A/IgE/IgG1/IgG4 antibodies and basophil response to HDMs were compared between V1 and V5 in both groups. Results: There were no significant differences in demographics, RTSS, skin reactivity to HDMs, or serum total/specific IgE levels to HDMs (P > 0.05, respectively) between the 2 groups. Nasal symptom score and RTSS decreased significantly at year 1 in the 2 groups (P < 0.05). There were no significant differences in percent decrease in nasal symptom score and RTSS at year 1 between the 2 groups (P > 0.05); however, rhinoscopic nasal symptom score decreased significantly in the SLIT-treated group (P < 0.05). Immunological studies showed that serum specific IgA levels (not specific IgE/IgG) and CD203c expression on basophils decreased significantly at V5 in the SLIT-treated group (P = 0.011 and P = 0.001, respectively), not in the control group. The control group required more medications compared to the treatment group, but there were no differences in adverse reactions. Conclusions: It is suggested that HDM-SLIT for 1 year could induce symptom improvement and may induce immunomodulation in elderly rhinitis patients.

• Journal of Korean Biological Nursing Science
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• 제4권2호
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• pp.69-77
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• 2002

The purpose of this study was to identify the relationship of symptom distress and natural killer cell cytotoxicity in breast cancer patients who had been radiation therapy and/or chemotherapy after surgery. Symptom distress measured by modified Lee's(1994) physical symptom questionnaire. For measuring the natural killer cell cytotoxic activity. 8ml to 10ml blood was collected from the subjects. Mononuclear cell was isolated by centrifuge of the blood and cultured by putting $Cr^{51}$, and reacted with target cell, K562 cell. Amount of $Cr^{51}$ was measured, and %lysis was calculated. The results were as follows. 1) Symptom distress score was 42.18, which is moderate symptom distress. 2) Natural killer cell cytotoxic activities were 42.18%lysis(effector : target cell ratio=100 : 1) and 28.05%lysis(effector : target cell ratio=50 : 1). 3) Correlation coefficients of symptom distress and natural killer cell cytotoxic activity were $-.134{\sim}-.461$. Though significant correlation was not found between total score of symptom distress and natural killer cell cytotoxic activity, 3('pain' 'feel hot on radiation site' and 'difficulty in breathing') of 19 symptom distress items and natural killer cell cytotoxic activity showed significant negative correlation(p<.05). These findings suggest that 1) breast cancer patients who had been radiation therapy and/or chemotherapy after surgery have moderate symptom distress and decreased natural killer cell cytotoxic activity. 2) The symptom distress was not related to natural killer cell cytotoxic activity.

• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3129-3133
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• 2012

Diagnosis and treatment procedures in cancers and resulting anxiety negatively affect the individual and the family. Particularly treatment methods may generate psychological symptoms. The aim of this study was to determine the level of such symptoms in Turkish gynecologic cancer patients receiving chemotherapy. A total of 41 patients who were referred to our gynecologic oncology research clinic between January-March 2012, receiving 3 months or more chemotherapy and who agreed to participate were enrolled in study. All the data were collected using a personal information form, Edmonton Symptom Assesment System and State-Trait Anxiety Inventory. Patients received highest point average from fatigue symptom ($6.53{\pm}2.67$) and lowest point average from dyspnea ($1.53{\pm}3.03$) according to Edmonton Symptom Assesment System. The mean State Anxiety score of patients was $43.1{\pm}9.77$ and mean Trait Anxiety score was $46.7{\pm}7.01$. Comparing symptoms of patients and mean State Anxiety score it was found that there was a statistically significant corelation with symptoms like pain (p<0.05), sadness (p<0.001), insomnia (p<0.05), state of well being (p<0.001) and dyspnea (p<0.05). Similarly comparing symptoms of patients and mean Trait Anxiety score demonstrated significant correlations for fatigue (p<0.05), sadness (p<0.01), insomnia (p<0.01) and state of well-being (p<0.01). As a result, patients with gynecological cancers experienced symptoms related to chemotherapy and a moderate level of anxiety. In accordance, appropriate interventions should recommended for the evaluation and improvement of anxiety and symptoms related to treatment in cancer patients.

• 대한한방소아과학회지
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• 제25권2호
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• pp.15-26
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• 2011

Objectives: The purpose of this study is to investigate the effect of Intranasal acupuncture treatment in allergic rhinitis patients. Methods: This study was carried with the 42 pediatric allergic rhinitis who had been treated in our hospital. Inner young-hyang was used for the intranasal acupuncture points. Their nasal cavity was observed via anterior rhinoscopy. We induced patient's inferior turbiante bleeding by acupuncture. Patients nasal symtoms and QOL(quality of life) were assessed by the Total Nasal Symptom Score(TNSS) and Quality of Life Questionnaire for Korean Rhinitisian(QLQKR). Results: Total Nasal Symptom Score(TNSS) and Quality of Life Questionnaire for Korean Rhinitisian(QLQKR) were significantly improved. Conclusions: Intranasal acupuncture treatment is relatively effective in treating pediatric allergic rhinitis.

• Journal of Yeungnam Medical Science
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• 제18권2호
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• pp.199-207
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• 2001

1999년 11월에서 2000년 4월까지 본 교실에서 비중격 성형술과 하비갑개 절제술 혹은 하비갑개 성형술을 시행 받고 3개월이상 추적 관찰이 가능하였던 45명의 성인환자를 대상으로 비중격 성형술 및 하비갑개 수술의 결과를 전향적으로 분석하였다. 수술 전 증상접수는 코막힘이 가장 높았으며 수술 후 전체적으로 모든 증상에서 통계학적으로 의미 있게 호전되었다(p<0.05). 수술 전 후의 음향비강통기도 검사에서 비강수축전의 경우에서 최소비강단면적은 큰 변화가 없었으나, C-절혼 면적과 비강체적은 의미 있게 증가되었다. 또한 증상의 호전도와 음향비강통기도 검사치의 변화와는 통계학적 연관성이 없었으나, 증상이 호전됨에 따라 최소비강단면적, C-절혼 면적, 비강체적이 증가하는 경향을 볼 수 있었다. 결론적으로 바중격 성형술 및 하비갑개 수술 후 결과 판정방법으로서 수술 전 후의 환자의 주관적인 증상을 접수화하여 어느 정도 객관성을 부여하였으며 수술 전 후의 음향비강통기도 검사를 이용하여 음향비장통기도 검사결과를 구하고 이를 바탕으로 증상접수의 호전도와 음향비강통기도 검사결과를 비교 분석함으로써 증상의 호전을 객관적으로 증명하였다.