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Effect of Chlorella vulgaris on lipid metabolism in Wistar rats fed high fat diet

  • Lee, Hee-Sun;Park, Hoon-Jung;Kim, Mi-Kyung
    • Nutrition Research and Practice
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    • v.2 no.4
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    • pp.204-210
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    • 2008
  • This study was performed to investigate effects of Chiarella vulgaris on lipid metabolism in rats fed high fat diet. Sixty 6-week-old male Wistar rats were divided into two groups; normal diet group and high fat diet group, then the rats in each group were further divided into three subgroups and fed 0%, 5% and 10% (w/w) chlorella-containing diets, respectively, and raised for 9 weeks, Serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activity and total protein and albumin concentration were not different among groups. Serum total lipids and liver TG concentration were significantly lower in 5% and 10% chlorella groups than 0% chlorella group in high fat diet groups (p<0.05). Serum TG, serum total cholesterol, liver total lipid and liver total cholesterol concentrations were significantly lower in 10% chlorella groups than 0% chlorella group in high fat diet groups (p<0.05). Fecal total lipid, TG and total cholesterol excretions were significantly higher in 5% and 10% chlorella groups than 0% chlorella groups in normal diet and high fat diet groups, respectively (p<0.05). These results suggest that Chlorella vulgaris is effective for prevention of dyslipidemia which may be due to the modulation of lipid metabolism and increased fecal excretion of lipid.

STEAM GENERATOR TUBE INTEGRITY ANALYSIS OF A TOTAL LOSS OF ALL HEAT SINKS ACCIDENT FOR WOLSONG NPP UNIT 1

  • Lim, Heok-Soon;Song, Tae-Young;Chi, Moon-Goo;Kim, Seoung-Rae
    • Nuclear Engineering and Technology
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    • v.46 no.1
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    • pp.39-46
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    • 2014
  • A total loss of all heat sinks is considered a severe accident with a low probability of occurrence. Following a total loss of all heat sinks, the degasser/condenser relief valves (DCRV) become the sole means available for the depressurization of the primary heat transport system. If a nuclear power plant has a total loss of heat sinks accident, high-temperature steam and differential pressure between the primary heat transport system (PHTS) and the steam generator (SG) secondary side can cause a SG tube creep rupture. To protect the PHTS during a total loss of all heat sinks accident, a sufficient depressurization capability of the degasser/condenser relief valve and the SG tube integrity is very important. Therefore, an accurate estimation of the discharge through these valves is necessary to assess the impact of the PHTS overprotection and the SG tube integrity of the primary circuit. This paper describes the analysis of DCRV discharge capacity and the SG tube integrity under a total loss of all heat sink using the CATHENA code. It was found that the DCRV's discharge capacity is enough to protect the overpressure in the PHTS, and the SG tube integrity is maintained in a total loss of all heat accident.

Status of Beverage and Water Intake among Adults in Korea - Data from Korea National Health and Nutrition Examination Survey 2019 - (한국 성인의 음료 및 수분 섭취 현황 - 국민건강영양조사 2019 자료를 이용하여 -)

  • Han, Gyusang
    • The Korean Journal of Food And Nutrition
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    • v.34 no.5
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    • pp.430-440
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    • 2021
  • This study was conducted to investigate the intake status of beverages and water in Korean adults using data from the 8th National Health and Nutrition Examination Survey. The 'total water' intake was 2,250.6 g for men and 1,871.2 g for women. Men and women consumed an average of 314.9 g of 'total beverages', of which 'coffee' was the largest at 107.5 g, followed by 'others'(65.4 g), 'milk' (44.8 g), 'soda' (44.1 g), 'teas' (20.9 g), and 'fruits and vegetables' (18.5 g). The intake of 'plain water' was 1,059.9 g, and the intake of 'water from food' consumed was 547.3 g. The 'total water' intake decreased with increasing age in males and females (p<0.001). Both men and women showed a tendency toward increased 'total water' intake as income levels increased. 'Plain water' intake accounted for 51.4% of the 'total water' intake in males and females. The intake of all nutrients significantly increased from the Q1 group to the Q4 group by quartile ranges of total water intake. The results of this study showed that the intake of healthy water should be considered, and care and educational programs are needed, especially for older people, to ensure adequate water intake.

Relationship of Phenolic Compounds and Free-radical Scavenging Activity in Black and Red Rice Extract

  • Hu, Gao-Sheng;Xu, Kai-Xiu;Jeong, Soon Jae;Kim, Doh-Hoon
    • Korean Journal of Breeding Science
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    • v.42 no.2
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    • pp.129-138
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    • 2010
  • Total phenolic content, total anthocyanin content and antioxidant activity were analyzed from rice samples collected in Korea, Japan and China. The results showed that the total phenolic content and free-radical scavenging activity differed significantly in these rice lines. The correlation between content and activity was subsequently investigated. The results showed that in black rice, anthocyanin was the major phenolic component and that both phenolic content and anthocyanin content were closely correlated with free-radical scavenging activity. Reverse Phase High Performance Liquid Chromatography (RP-HPLC) data showed that cyanidin-3-O-glucoside and peonidin-3-O-glucoside composed about 90% of the total anthocyanin content in black rice and in red rice. In the red rice extract, the total phenolic content produced a high correlation coefficient with antioxidant activity but correlated very poorly with the total anthocyanin content. The $OD_{458}$ and the $OD_{500}$ values which represent the proanthocyanidin content of the rice extract, produced high correlation coefficients with antioxidant activity and total phenolic content. These results suggest that the $OD_{458}$ and the $OD_{500}$ values can be used to evaluate the quality of red rice. In addition, based on the data obtained, a competitive accumulation model of anthocyanin and proanthocyanidin in black and red rice was proposed.

Changes in Antioxidant Activity and Total Phenolic Content of Water Spinach (Ipomoea aquatic Forsk.) under In Vitro Biomimicking System

  • Lee, A-Young;Kim, Young-Suk;Shim, Soon-Mi
    • Food Engineering Progress
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    • v.14 no.4
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    • pp.342-345
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    • 2010
  • The purpose of current study was to examine bioaccessibility of antioxidant activity and total phenolic content in each part of water spinach (Ipomoea aquatic Forsk.). In vitro biomimicking system simulated human digestive fluid was employed in order to measure bioavailable anti-oxidative effect and phenolic content. Antioxidant activity and total phenolic content was measured by using the DPPH method and the Folin-Ciocalteu assay, respectively. Stem of water spinach had a higher DPPH free radical scavenging effect (5.43 mg/mL for $IC_{50}$) than leaf (5.95 mg/mL for $IC_{50}$), while leaf had a greater level of total phenolic content (287.45 ${\mu}g$ GAE/mL) than stem (216.45 ${\mu}g$ GAE/mL). Bioaccessible antioxidant capacity and digestive stability of total phenolic content showed a similar pattern to what found in raw materials. Our result also indicated that total phenolic content was not found to be a major marker for prediction of antioxidant activity. It is plausible that other constituents such as vitamin E and C in water spinach could be contributors for antioxidant activities.

Assessing agricultural competitiveness of cities and counties in Gyeongbuk

  • Jeong, Jaewon;Kim, Hyun Seok
    • Korean Journal of Agricultural Science
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    • v.45 no.4
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    • pp.871-878
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    • 2018
  • The government of Gyeongbuk in Korea increased the financial input in the agricultural sector by 43% from 2008 through 2012. However, the productivity of the agricultural sector in Gyeongbuk rose only about 3.6% during the same period. This study evaluated the agricultural competitiveness of each city or county in Gyeongbuk using six evaluation indices (scale, productivity, finance input, location quotient, technical education, and total) and investigated the relationship between the indices and total values of agricultural productions. The results show that Sangju, Gyeongju, Andong, Uiseong, and Seongju have high competitiveness for the scale index. For the productivity index, Gimcheon, Mungyeong, Ulleung, Yeongju, and Seongju were highly evaluated. For the location quotient index, Yeongcheon, Uiseong, Cheongdo, Seongju, and Sangju have high competitiveness. Uiseong, Yeongdeok, Cheongsong, Gunwi, and Yeongyang were highly evaluated for the agricultural finance input index. For the agricultural technical education index, Chilgok, Sangju, Mungyeong, Uiseong, and Gyeongju have high competitiveness. Finally, Sangju, Euiseong, Yeongcheon, Gyeongju, and Andong were highly evaluated for the total competitive index, while Yeongdeok, Yeongyang, Goryeong, Uljin, and Cheongsong have a low competitiveness for the total competitive index. This study also found that out of five indices, scale, location quotient, and technical education indices have a positive and statistically significant effect on the total values of agricultural production. However, we did not find any statistically significant effect of the productivity and finance input indices on the total values of agricultural production. Hence, we can conclude that the government should focus their agricultural policy on scale, location quotient and education to improve total agricultural production.

Analysis of the Correlation between Activity of the Suprahyoid Muscles, Infrahyoid Muscles and the New VFSS Scale in Stroke Patients with Dysphagia

  • Lee, Hyun-Jin;Kim, Kyoung-Don
    • Journal of the Korean Society of Physical Medicine
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    • v.13 no.4
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    • pp.19-25
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    • 2018
  • PURPOSE: This study was conducted to investigate the correlation between the activity of suprahyoid muscles, infrahyoid muscles and swallowing ability in stroke patients with dysphagia. METHODS: The subjects of this study were 120 patients who were diagnosed with CT or MRI stroke and had swallowing disorder at Daegu Metropolitan General Hospital from August 2014 to February 2017. The suprahyoid and infrahyoid muscle activity was measured in patients with dysphagia and the new videofluoroscopy swallowing studies scale (new VFSS scale) was used for evaluation of swallowing function. Correlation analysis was conducted using the measured data. RESULTS: The activities of suprahyoid muscles were 325.8 (%RVC) on average, while the average infrahyoid muscle activity was 302.65 (%RVC) and the average value of the new VFSS scale was 31.52. The total for oral organs was 3.62 on average and that for pharynx organs was 28.30 on average. The activity of the suprahyoid muscles showed a significant positive correlation with the activity of the infrahyoid muscles, but a significant negative correlation with the total oral phase, total pharyngeal phase and total new VFSS scale (p<.01). The activity of the infrahyoid muscles showed a significant negative correlation with the total oral phase, total pharyngeal phase, and total new VFSS (p<.01). CONCLUSION: Based on the results of this study, it is necessary for researchers to consider the infrahyoid and suprahyoid muscles when conducting swallowing rehabilitation.

Impacts of Capital Structure on Business Efficiency of Listed Joint Stock Commercial Banks in Vietnam Stock Market

  • DOAN, Quyen Thuc;HO, Thu Thi Hoai;DOAN, Quynh Huong
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.8
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    • pp.99-108
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    • 2022
  • This study aims to examine the influence of capital structure on the business efficiency of joint stock commercial banks listed on the Vietnamese stock market. The article uses data collected from the financial statements of 15 prominent joint-stock commercial banks out of 27 joint-stock commercial banks listed in Vietnam from 2011 to 2021. The research uses E-view software in quantitative analysis to build regression models to determine the relationship and the impact of capital structure factors on the business efficiency of listed joint stock commercial banks. Research results show that ROA is affected by 2 variables of capital structure. It is the sum of customer deposits to total assets and total liabilities to total equity. Total debt to total equity and total customer deposits to total assets both have a negative effect on ROA. For the regression results of ROA with all control variables, the control variables have a positive relationship with the dependent variable. The article has provided recommendations based on the research findings to determine the proper capital structure. Managers must solve the outstanding amount of mobilized capital in previous years, combined with the bad debt handling activities that have arisen.

Analysis of Factors Affecting Regional Total Fertility Rate: Using a Model Considering Cross-sectional Dependence (지역 합계출산율에 영향을 미치는 요인 분석: 횡단면 의존성을 고려한 모형을 이용하여)

  • So-Youn Kim;Su-Yeol Ryu
    • Asia-Pacific Journal of Business
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    • v.15 no.1
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    • pp.335-352
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    • 2024
  • Purpose - Low fertility rate is a serious problem, and this study analyzes factors affecting total fertility rate using panel data from 16 metropolitan cities and provinces in Korea from 2000 to 2022. Design/methodology/approach - Estimating the SAR model considering the weak cross-sectional dependence that exists in variables related to the regional total fertility rate, and using the DKSE estimation method considering the strong cross-sectional dependence. Findings - Estimation results considering weak and strong cross-sectional dependence were similar, confirming the robustness of the results. Female labor force participation rate has a positive effect on total fertility rate, and employment rate has no effect. However, the interaction term is a negative (-) sign. Crude marriage rate has a positive effect on total fertility rate, and apartment price has a slightly positive effect. Environmental factor has no effect, and policy factor has a negative effect. Research implications or Originality - In order for an increase in the female labor force participation rate to lead to an increase in the total fertility rate, qualitative improvements in female employment must be made. Financial investment policies for childbirth must increase their effectiveness. The problem of low fertility rate requires not only population policy but also social, economic, cultural, environmental, and policy conditions to be considered.

Optimization of Total Arc Degree for Stereotactic Radiotherapy by Using Integral Biologically Effective Dose and Irradiated Volume (정위방사선치료 시 적분 생물학적 유효선량 및 방사선조사용적을 이용한 Total Arc Degree의 최적화)

  • Lim Do Hoon;Lee Myung Za;Chun Ha Chung;Kim Dae Yong
    • Radiation Oncology Journal
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    • v.19 no.2
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    • pp.199-204
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    • 2001
  • Purpoe : To find the optimal values of total arc degree to protect the normal brain tissue from high dose radiation in stereotactic radiotherapy planning. Methods and Materials : With Xknife-3 planning system & 4 MV linear accelerator, the authors planned under various values of parameters. One isocenter, 12, 20, 30, 40, 50, and 60 mm of collimator diameters, $100^{\circ},\;200^{\circ},\;300^{\circ},\;400^{\circ}C,\;500^{\circ},\;600^{\circ}$ or total arc degrees, and $30^{\circ}\;or\;45^{\circ}$ or arc intervals were used. After the completion of planning, the plans were compared each other using $V_{50}$ (the volume of normal brain that is delivered high dose radiation) and integral biologically effective dose. Results : At $30^{\circ}$ of arc interval, the values of $V_{50}$ had the decreased pattern with the increase of total arc degree in any collimator diameter. At 45 arc interval, up to $400^{\circ}$ of total arc degree, the values of $ V_{50}$ decreased with the increase of total arc degree, but at $500^{\circ}\;and\;600^{\circ}$ of total arc degrees, the values increased. At $30^{\circ}$ of arc interval, integral biologically effective dose showed the decreased pattern with the increase of total arc degree in any collimator diameter. At $45^{\circ}$ arc interval with less than 40 mm collimator diameter, the integral biologically effective dose decreased with the increase of total arc degree, but with n and n mm or collimator diameters, up to $400^{\circ}$ or total arc degree, integral biologically effective dose decreased with the increase of total arc degree, but at $500^{\circ}\;and\;600^{\circ}$ of total arc degrees, the values increased. Conclusion : In the stereotactic radiotherapy planning for brain lesions, planning with $400^{\circ}$ of total arc degree is optimal. Especially, when the larger collimator more than 50 mm diameter should be used, the uses of $500^{\circ}\;and\;600^{\circ}$ of total arc degrees make the increase of$V_{50}$ and integral biologically effective dose. Therefore stereotactic radiotherapy planning using $400^{\circ}$ of total arc degree can increase the therapeutic ratio and produce the effective outcome in the management of personal and mechanical sources in radiotherapy department.

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