• The Journal of Internal Korean Medicine
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• v.15 no.1
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• pp.60-79
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• 1994

The studies were conducted to investigate the combined effects of Tonics and Mitomycin C(MMC). The effects of Tonics and MMC on the proliferation of Molt-4 cells, human leukemic cell line, and activation of human lymphocytes were estimated by MTT colorimetric assays. Selected medicines among 9 kinds of Tonics by results of MTT assays were treated with MMC in mice. The Tonics itself enhanced the proliferation of Molt-4, but the anti-proliferative effect of MMC was not intercalated by the combined treatment of Tonic and MMC. Inhibitory action of MMC was augmented by Sa Kun Ja Tang(SKT). This result was due to the inhibition of DNA synthesis. Among 9 kinds of Tonics, Sip Jean Dae Bo Tang(SDT), Saeng Maek San(SMS) and Kwi Bi Tang(KBT) did not inhibit the action of MMC, but activated lymphocytes. When the mice were treated by MMC, the number of leukocytes was decreased significantly at the 1st day, but recovered at the 7th day. In the groups of MMC treated with SDT or KBT, the number of leukocytes was increased significantly than the group of MMC treated only at the 3rd day. Combined treatment of the Tonics(SDT, SMS) and MMC retained the body weight of mice at the level of normal mice. SDT, SMS and KBT did not change the number of plaque forming cells(PFC), but MMC treated group decreased the number of PFC. The combined treatment of MMC and SDT increased the number of PFC significantly than the MMC treated group. SDT, SMS and KBT did not influence the proliferation of T cells, but MMC treated group decreased the proliferation of T cells. The combined treatment of MMC and those tonics increased the T cell proliferation significantly than the MMC treated group. In conclusion, the results presented in this paper suggest that SDT, SMS and KBT can recover the side effects of MMC, such as weight loss, leukopenia and immunosuppresion, without any intercalating the anti-proliferative action of MMC in vivo.

• Journal of Applied Biological Chemistry
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• v.60 no.4
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• pp.313-319
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• 2017

Strawberries are one of the main commodities in Korea and have been exported over 30 million dollar. And the safety has recently become an important issue in the agro-trade, pesticide residue is most important matter of safe agricultural products. As strawberries can be cultivated using elevated production system, so it is possible to use the drenching. When spraying the pesticides, the use of drenching can be lower amount of residual than using foliar treatment. In this study, time sequential residual amount of pesticides were compared between drenching and foliar application in strawberries. Pesticides were treated with the standard and double dosage and samples were collected at 0, 3, 6, 9, 13, 16 and 21 day and analyzed by LC and LC-MS/MS after liquid-liquid extraction and QuEChERS. Two pesticides were detected less than 1 mg/kg in all samples for drenching treatment. Carbendazim residues in drenching treatment were 5 to 25 times lower than foliar application. And azoxystrobin was not detected in strawberries of drenching treatment.

• Journal of the Korean association of regional geographers
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• v.19 no.4
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• pp.668-682
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• 2013

This study illustrates the mechanism of The Decrease of Korean population in Yanbian Korean Autonomous Prefecture (YBKAP) and some changes of regional characteristics since China's economic reforming. Due to China's Implementing market economic system, deregulating in family register system, higher mobility since establishing Sino-Korean diplomatic relations, the expansion of intermarriages and residential areas, Korean community is confronted with lower birthrate and continuous mobility of the young and women. It directly connects to a decrease in urban population and aging, causing a decline in farming production, disintegrating of Korean community, weakening the function of villagers' organization, shrinking in Korean education and leaderships. For supplementing the shorted labor, Chinese farmers from other areas flow into the YBKAP, showing some different trends, such as farming Chinesization, Chinese farmers' higher economic level than Korean, the Korean traditional paddy field transforming into dry farmland with single-crop farming and pursuing commercial production in labor management. At the moment, declining population in Korean community in rural areas means that the community could not respond the changes of farming environments appropriately and in some way it is facing with the crisis of die away from the Chinese society. It needs an unconventional support and development policies in YBKAP rural areas.

• The Korean Journal of Food And Nutrition
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• v.25 no.2
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• pp.407-412
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• 2012

Wild grass is edible, and it grows in the mountains or field areas. Wild grass has diverse biological effects, such as antiobesity, anti-cancer, antioxidant activities and immune stimulation. Currently, many studies are aimed at enhancing the efficacy of medicinal foods on biological activity using a bioconversion technology, including the fermentation process. In this study, the quality characteristics and antioxidative activity of the fermented wild grass was investigated. The antioxidant activity of fermented wild grass was assessed by various radical scavenging assays using DPPH(2,2-diphenyl-1-picrylhydrazyl), FRAP(ferric ion reducing antioxidant power), reducing power, and ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)). Moisture contents of the fermented wild grass is $49.6{\pm}0.06%$. Contents of crude ash, crude protein, and crude fat were $0.65{\pm}0.01$, $0.65{\pm}0.04$, and $3.3{\pm}0.59%$, respectively. Moreover, fermented wild grass showed that the hunter's color values were 80.36(lightnees), 11.47(redness), and 44.53(yellowness), respectively. Total phenolic contents of the fermented wild grass was $1,185{\pm}159{\mu}g$ GAE(gallic acid equivalent)/g. The antioxidative activities of the fermented wild grass were significantly increased in a dose dependent manner. In addition, fermented wild grass did not show any cytotoxicity up to 500 ${\mu}g/m{\ell}$. However, the anti-adipogenic effect of the fermented wild grass extract was barely detectable. This antioxidant potential is partly due to the phenolic compounds that are present in the fermented wild grass extracts.

• Korean Chemical Engineering Research
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• v.40 no.6
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• pp.763-768
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• 2002

This study was performed in the airlift bioreactor using the nitrifier consortium entrapped in polyvinyl alcohol(PVA) for removing low concentration total ammonia nitrogen(TAN). At the superficial air velocity of 0.83 cm/sec, TAN removal rate and removal efficiency was $316.6{\pm}7.2g/m^3{\cdot}day$ and $92.8{\pm}2.2%$ respectively. Removal rate was continuously increased with decreasing hydraulic residence time(HRT) from 0.5 hr to 0.05 hr, whereas removal efficiency decreased with decreasing HRT. The optimum temperature for nitrification was $30^{\circ}C$ at which removal efficiency was $95.5{\pm}1.5%$. Nitrification was effectively performed at low temperature, $10^{\circ}C$. In the pH range from 7 to 9 in the bioreactor, removal rate and removal efficiency was $310{\pm}10g/m^3{\cdot}day$ and $94{\pm}3%$ respectively.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.32 no.4 s.59
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• pp.209-217
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• 2006

Emulsion is a dispersion system among liquids which are not miscible together. There are numerous cosmetic raw materials which have different physicochemical properties. Therefore, emulsion technology is very useful in cosmetics. With the development of emulsifier, several emulsification technologies have been developed. Since HLB method by Griffin in 1950's, PIT method, gel method, and D-phase methods, etc, have been developed. Recently, the application of natural emulsifier and polymeric emulsifier increases in cosmetics in order to achieve enhanced safety and biocompatibility. Besides nano-emulsion, multiple-emulsion, liquid crystal emulsion, and Pickering emulsion have been developed and applied as means of differentiating appearance and texture of products and achieving enhanced delivery of active ingredients. Meanwhile, the application studies of nano-dispersed structural system such as liposome or cubosome are on progress. Liposome is a bi- or multi-lamella layer dispersion system composed of amhiphilic molecules - phospholipids which are main components of plasma membrane. Cubosome also is a nano-sized dispersion system composed of a specific molecule like glyceryl monoloeate derived from natural products. And it has a cubic bicontinuous structure in water due to its unique molecular structure. Incorporating compounds (active materials) into such nano-particles can increase biocompatibility and delivery efficiency of target compounds. Manufacturing process and application of cosmetic emulsions and nano-particles are briefly introduced in this paper.

• Journal of The Korean Association of Information Education
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• v.22 no.5
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• pp.509-517
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• 2018

As the necessity of maker education is being emphasized and the app generation is now entering school, expectations concerning the impact of app development education are rising in the field of education. The introduction and rise in popularity of a new type of education, such as app development education, requires a change in attitude among teachers. Therefore, this study focused on the concerns of in-service teachers regarding app development education by applying the Concerns-Based Adoption Model (CBAM) of Hall and Hord (2015). For this purpose, the data was collected from 23 in-service teachers who attended a short teacher training session that introduced app development training. The data was converted to the relative intensity based on the stage of concerns questionnaire (SoCQ) scoring device and was expressed as the SoCQ profile. The results of the survey concerning app development education showed that the stage 0 concern (unconcerned) was reported most frequently by teachers and the stage 4 concern (consequence) was reported least frequently. This kind of result, which is typical at the beginning of the introduction of a new education program, indicates that teachers recognize app development education but do not have sufficient information regarding it. Qualitative results also showed that teachers understand the educational possibilities of app development education, but they were worried about the difficulties expected to be applied in the field. Based on these results, we suggest that more detailed information on app development education be provided through teacher training.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.47 no.12
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• pp.17-23
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• 2010

In the mobile cloud computing, the mobile node should request and receive the services while being connected. In PMIPv6, all packets sent by mobile nodes or correspondent nodes are transferred through the local mobility anchor. This unnecessary detour still results in high delivery latency and significant processing cost. Several PMIPv6 route optimization schemes have been proposed to solve this issue. However, they also suffer from the high signaling costs and handover latency when determining the optimized path. We propose the route optimization handover scheme which adopts the prediction algorithm in PFMIPv6. In the proposed scheme, the new mobile access gateway establishes the bi-directional tunnel with the correspondent node's MAG using the context message when the mobile node's handover is imminent. This tunnel may eliminate the need of separate route optimization procedure. Hence, the proposed scheme can reduce the signaling cost than other conventional schemes do. Analytical performance evaluation is preformed to show the effectiveness of the proposed scheme. The result shows that our scheme is more effective than other schemes.

• Journal of the Korean Ceramic Society
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• v.35 no.6
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• pp.594-602
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• 1998

Titanium hydroxide (TiO({{{{ {OH }_{2 } }})) fine particles were produced by the reverse micelle technique. For the formation of titanium hydroxide (TiO({{{{ {OH }_{2 } }})) particles with the technique reversed micellar solution was prepared by solubilizing water into organic solvent (isooctane) with a surfactant and titanium alkoxide (tetraisopropyl orthotitanate) diluted with isopropyl alcohol was added to the reversed micellar solution. The hdrolyzed species (TiO({{{{ {OH }_{2 } }})) was formed by the hydrolysis of titanium alkoxide and titanium dioxide is then formed by the condensation of the hydrolyzed species. There are several process variables such as surfactants concentration of surface cosurfactant hydrolysis temperature and pH. In this work the ef-fects of process variables on paticle shapes particle size distribution and paticle agglomeration were bi-nodal for an anionic surfactant(AOT) in the whole range of temperature pH and surfactant concentration of this experiment. The addition of ethanol as a cosurfactant resulted in narrow particle size distribution of the experiment. The additiono of ethanol as a cosurfactant resulted in narrow particle size distribution and 0.12${\mu}{\textrm}{m}$ of smaller average particle diameter. FT-IR spectrum of particles shows the absorption peak of Ti-OH bonding and Ti-O bonding. An exothermic peak around 41$0^{\circ}C$ in TGA-DTA curve shows that crys- tallized anatase phase appears and completely transits to anatase around 45$0^{\circ}C$.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.33 no.2
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• pp.739-748
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• 2013

In this study, analytical works for the induced winds due to traveling vehicles on highway have been conducted by Computation Fluid Dynamics (CFD). The traveling condition was considered in two cases: (a) single direction and (b) bi-direction. The analysis was focused on the effects of the induced winds on the upper part of a median strip while the aerodynamic characteristics of the vehicles were directly analyzed in the previous studies. From the analysis results, it has been found that the maximum magnitude of the induced winds was 2.2 m/s when the vehicles travel with the speed of 50 km/h. Additionally, 4.0 m/s and 5.3 m/s were obtained with the speed of 90 km/h and 120 km/h, respectively. Especially, the induced winds was generated about 84% of the vehicle speed at 1.0 m above from the median strip when the vehicles travel with the speed of 120 km/h. The induced winds was maintained during the very short period while the traveling. conclusively, it is noted that the wind power generation can be possible by using the small-sized wind power generators installed on median strips throughout the analytical results in this study.