• Title/Summary/Keyword: Tm3+

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Effects of the mixture of fenugreek seeds and Lespedeza cuneata extracts on testosterone synthesis in TM3 cells oxidative stressed with H2O2 (호로파와 야관문 복합추출물이 과산화수소로 산화적 스트레스가 가해진 TM3 세포의 테스토스테론 합성에 미치는 영향)

  • Lee, Kyeong Soo;Lee, Eun Kyoung;Seo, Yoonhee;Choe, Soo Young
    • Journal of Applied Biological Chemistry
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    • v.59 no.4
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    • pp.305-311
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    • 2016
  • This study investigated the effects of a mixture of fenugreek seeds and Lespedeza cuneata extracts on testosterone synthesis in TM3 cells that were oxidatively stressed with $H_2O_2$. In order to oxidatively stress TM3 cells, the cells were treated with $50{\mu}M$ hydrogen peroxide for 4 hr in serum-free media. Yagwanmun-horopa mixture (YHM) showed neither cytotoxicity nor increment of cell proliferation in the oxidatively stressed TM3 cells in any concentration. When the cells were treated with hydrogen peroxide, testosterone levels decreased, but the testosterone level was returned to that of the control level in the presence of YHM. In order to find out the reasons for the increase of testosterone, the expression of the genes involved in the synthesis or disintegration of testosterone. On the other hand, the levels of $3{\beta}$-HSD4 and 17, 20-desmorase, which are involved in testosterone synthesis, were decreased through the use of hydrogen peroxide and were recovered through YHM treatment. Aromatase and $5{\alpha}$-reductase2, which convert testosterone to estradiol and dihydrotestosterone, respectively, were increased through the use of hydrogen peroxide, and were returned to control level through YHM treatment. These results suggest that YHM does not affect TM3 cell proliferation. However, YHM increases the expression of testosterone-synthesizing enzyme, which was decreased through oxidative stress, and decreases the expression of testosterone- converting enzyme, which was increased through oxidative stress. Therefore, it is reasonable that YHM has strong recovery activity on testosterone to normal level, even in the oxidatively stressed TM3 cells which mimics the andropause state.

A Numerical Analysis on the Nozzle-Rotor of a 3-D Supersonic Turbine (3차원 초음속 터빈의 노즐-로터 상호작용에 관한 수치적 연구)

  • Yun Won-Kun;Shin Bong-Gun;Kim Kui-Soon;Kim Jin-Han;Jeong Eun-Hwan
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • v.y2005m4
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    • pp.413-422
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    • 2005
  • In this paper, numerical results for 3-D supersonic turbine flow have been firstly compared with the experimental results to verify results computed by $Fine^{TM}/Turbo$. It was found that $Fine^{TM}/Turbo$ can accurately predict flow characteristics within supersonic turbine. Next, an grid system for 3D turbine flow was optimized selected through grid independency test. Finally the effect of axial gap between rotor and nozzle and chamfer angle of blade edge on the flow characteristics within 3-D supersonic turbine was analyzed with Frozen Rotor method.

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Rotavirus Vaccines (로타바이러스 백신)

  • Koh, Hong
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.12 no.sup1
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    • pp.72-76
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    • 2009
  • Rotavirus infection is the leading cause of severe diarrhea disease in infants and young children worldwide. Rotavirus infects every child at least once by her/his $5^{th}$ birthday. It has been known that single episode of rotavirus infection can protect or alleviate subsequent illness caused by both homotypic and heterotypic rotaviruses. There are two currently licensed rotavirus vaccines. One is human-bovine rotavirus reassortant pentavalent vaccine ($RotaTeq^{TM}$), which contains five reassortant rotavirus (expressing protein G1, G2, G3, G4 and P[8]) and was licensed in Korea for use among infants in 2007. Another is live-attenuated human rotavirus vaccine ($Rotarix^{TM}$) derived from 89-12 strain which represents the most common of the human rotavirus VP7(G1) and VP4(P[8]) antigens. $Rotarix^{TM}$ was licensed in Korea in 2008. Both live oral rotavirus vaccines are efficacious in preventing severe rotavirus gastroenteritis.

Giant Perpendicular Magnetic Anisotropy of a Fe(001) Surface: A Density Functional Study

  • Odkhuu, D.;Rhim, S.H.;Yun, Won Seok;Hong, S.C.
    • Proceedings of the Korean Magnestics Society Conference
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    • 2013.12a
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    • pp.29-29
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    • 2013
  • We predict agigantic perpendicular magnetocrystalline anisotropy (MCA) in Fe (001) capped by 5d transition metal (TM) overlayers by using first principles calculations. Analysis of atom-by-atom contribution to MCA reveals that gigantic MCA as large as 11 meV/TM originates not from Fe atoms but from the 5d TMs through the strong spin-orbit coupling. More specifically, it is the hybridization between TM and Fe d orbitals that also induces non-negligible magnetic moments in TM. Furthermore, spin-channel decompositions of MCA matrix with and without the presence of Fe substrate identify the electronic origin of the perpendicular MCA that the down-down channel contribution plays the most crucial role for the sign changes of MCA of TM overlayers upon the hybridization with Fe-3d.

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Temperature Dependence of Magnetization of Amorphous TM_70 Cr_5 Si_10 B_15 (TM=Fe, Co, Ni) Alloys

  • Kim, Kyeong-Sup;Yu, Seong-Cho;Lim, Woo-Young;Myuong, Wha-Nam
    • Journal of Magnetics
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    • v.2 no.4
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    • pp.135-137
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    • 1997
  • We report the salient features of the magnetic properties of amorphous TM70Cr5Si10B15(TM=Fe, Co, Ni) alloys. The temperature dependence of magnetization for amorphous ribbons were measured by a SQUID and a VSM from 5 K to 700 K under an external field of 10 kOe. Except TM70Cr5Si10B15 that shows a paramagnetic behaviour, both Fe and Co based amorphous alloys show a typical ferromagnetic thermo-magnetization curves. For these two ferromagnetic alloys, the saturation magnetization in the temperature range from 5 K to about 0.4 Tc can be descrived by the Bloch relation, Ms (T)=Ms(0) [1-BT3/2-CT5/2]. The spin wave stiffness constants and the range of exchange interaction were analyzed from the magnetization behaviour. The variation of the magnetic properties are discussed and compared with the composition of the alloys.

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Video Rate Control Using An Adaptive Quantization Based on Spatio-temporal Activity Measure (시공간 활성도를 이용한 적응적 양자화 기반 비디오율 제어)

  • 이시웅;김차종
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2004.05b
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    • pp.454-458
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    • 2004
  • A new algorithm for the rate control of videos considering the sensitivity of the human visual system is presented. The method adopts the three-step structure of MPEG2 TM5 rate control, and a new measure of macroblock activity based on spatio-temporal sensitivity is introduced for the adaptive quantization. Experimental results show that the spatio-temporal activity measure outperforms the spatial activity of TM5 in picture quality.

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Antimicrobial Susceptibility of Bordetella bronchiseptica Isolates from Pigs (돼지에서 분리한 Bordetella bronchiseptica의 항생제 감수성)

  • 조정곤
    • Journal of Veterinary Clinics
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    • v.15 no.1
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    • pp.30-35
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    • 1998
  • Susceptibility or resistance of the Bordetella bronchiseptica was determined by using the broth microdilution method. Each Bordetella bronchiseptica was tested fur sutraceptluility with 7 different antimicrobial agents.4 high prevalence of resistance (greater than 80 %) was found when Bordetella bronchiseptica was tested with amikacin (AK), ciprofloxacin ILrJl gentamlcin IGAgf, kanamycin (Kbf) and tobramycin (TM). However, the Bordetella bronchiseptica were sensitive to chloramphenicol (CP) and tetracycline (TC). Three different combination of drug resistance were observed : AM-CF-GM-TM (1 strain), AM-CF-GM- KM-TM (45 strains), and AM-CF-GM-KM-TM-CP (3 strains). The MICs against Bordetella bronchiseptica were 0.13 to >2.00 for TC, 4 to >648 for CP, 8 to >128 for CF 16 to >256 for GM, 16 to >256 for TM, 32 to >256 for KM and 64 to 256 for AM.

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Electrochemical Behavior of Tm ion and Bi ion in LiCl-KCl Molten Salt

  • Kim, Beom-Kyu;Han, Hwa Jeong;Park, Ji Hye;Kim, Won Ki;Park, Byung Gi
    • Proceedings of the Korean Radioactive Waste Society Conference
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    • 2017.10a
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    • pp.83-84
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    • 2017
  • This study, electrolytic behavior of Thulium and Tm-Bi ion system was studied. The electrochemical behavior of Tm was studied in $LiCl-KCl-TmCl_3$ molten salts using electrochemical techniques Cyclic Voltammetry on tungsten electrodes at 773K. During the process of CV and SWV, intermetallic compound were observed Bi-Tm. Further study, in order to determine clarity of diffusion coefficient in this experiment, we will compare result of electrochemistry method and we also need to quantitative research.

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Luminescence Properties of $Dy^{3+}-(or Tm^{3+}-)$ Doped $Ga_2O_3$ and $ZnGa_2O_4$ Phosphors

  • Ryu, Ho-Jin;Park, Hee-Dong
    • The Korean Journal of Ceramics
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    • v.3 no.2
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    • pp.134-138
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    • 1997
  • $Dy^{3+}-(or Tm^{3+}-)$ doped $Ga_2O_3 \;and\; ZnGa_2O_4$ phosphors were prepared using the solid state reaction method to investigate their photoluminescent characteristics. Under 254 nm excitation, $Dy^{3+}-doped Ga2_O_3$ exhibited two emission bands of 460~505nm and 570~600nm. On the other hand, $Dy^{3+}-(or Tm^{3+}-)$ doped $ZnGa_2O_4 $phosphors exhibited a broad-band emission extending from 330 nm to 610 nm, peaking at about 430 nm(or 370 nm). In this study, an emission peak shift of nealy 50 nm towards longer wavelength region was observed with $Dy^{3+}$ doping in the $ZnGa_2O_4 $.

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A Case Report : The Measurement Results of Duchenne Muscular Dystrophy Patient Using Sensitiv ImagoTM and Ryodoraku (Sensitiv ImagoTM, 양도락을 이용한 Duchenne Muscular Dystrophy 환아 1례의 검사 결과 보고)

  • Han, Ju Hui;Kim, Deog Gon;Lee, Jin Yong
    • The Journal of Pediatrics of Korean Medicine
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    • v.28 no.3
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    • pp.74-84
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    • 2014
  • Objectives The purpose of this study is to report the measurement results of Duchenne Muscular Dystrophy (DMD) in Patient Using Sensitiv $Imago^{TM}$ (SI) and Ryodoraku. Methods We conducted SI test and Ryodoraku test to a 7-year-old DMD patient who visited to Oriental pediatrics, Kyung Hee Medical Center. Results We obtained SI and Ryodoraku test results from a DMD patient. Conclusions Further study with more samples is necessary to establish accuracy of SI in clinical use.