• 제목/요약/키워드: Tissues distribution

검색결과 548건 처리시간 0.025초

Intensity Modulated Radiation Therapy of Brain Tumor

  • Kim, Sung-Kyu;Kim, Myung-Se
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 한국의학물리학회 2002년도 Proceedings
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    • pp.61-64
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    • 2002
  • As intensity modulated radiation therapy compared with conventional radiation therapy, tumor target dose increased and normal tissues and critical organs dose reduced. In brain tumor, treatment planning of intensity modulated radiation therapy was practiced in 4MV, 6MV, 15MV X-ray energy. In these X-ray energy, was considered the dose distribution and dose volume histogram. As 4MV X-ray compared with 6MV and 15MV, maximum dose of right optic-nerve increased 10.1 %, 8.4%. Right eye increased 5.2%, 2.7%. And left optic-nerve, left eye, optic chiasm and brainstem incrased 1.7% - 5.2%. Even though maximum dose of PTV and these critical organs show different from 1.7% - 10.1% according to X-ray energies, these are a piont dose. Therefore in brain tumor, treatment planning of intensity modulated radiation therapy in 9 treatment field showed no relation with energy dependency.

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Mediastinal Leiomyoma -Report of a case- (종격동 평활근종의 1례)

  • 홍기우;김세화;이홍균
    • Journal of Chest Surgery
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    • 제7권1호
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    • pp.117-122
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    • 1974
  • The benign tumor of smooth muscle, the leiomyoma, may arise anywhere in the body, in such tissues as the muscularis of the gut and the media of blood vessels, although by far its most common location is the uterus. Indeed, the mediastinal leiomyomas are extremely rare, especially when one excludes those arising in the esophagus. No dogmatic statements can be made with regard to age, sex distribution, symptoms, or clinical course because of the extreme paucity of cases available for evaluation. Although the majority of the reported cases are in the posterior mediastinum, thus suggesting esophageal origin. We have experienced a right inferior mediastinal leiomyoma in 36 years old housewife. She complained hemoptysis and right lower chest pain associated with intermittent low-graded fever and chillness. Routine X-ray film revealed a large irregular cystic mass density in the right lower thoracic cavity. On exploratory thoracotomy, a huge round yellow-gray colored solid mass, measured about 2.5kg in weight, was located in the right inferior mediastinum just above right hemidiaphragm, medially. The tumor mass was removed, being proved to be leiomyoma on histopathologic examination. Her postoperative course was uneventful and discharged without complication.

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Modified Monopole Antenna for Microwave Thermal Therapy (마이크로파 에너지를 이용한 열 치료용 링-모노폴 안테나)

  • 문명호;곽상태
    • Proceedings of the Korea Electromagnetic Engineering Society Conference
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    • 한국전자파학회 2001년도 종합학술발표회 논문집 Vol.11 No.1
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    • pp.86-90
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    • 2001
  • Modified coaxial-slot antenna for minimally invasive microwave thermal therapy for liver tumor is studied in this paper. Minimally invasive microwave antenna in medicine are applied for hyperthermia for medical treatment for cancer, cardiac catheter ablation for ventricular arrhythmias treatments, microwave treatment of Benign prostatic hypertrophy, and so on. Microwave hyperthermal ablation for liver tumors is expected for enthusiasts as an alternative to curative surgical resection. Tumors have to heated up to 60 degree C to coagulate .cancer cells but less than 100 degree C to avoid evaporation. Temperature dependence of properties of the tissues should be considered for wide range of treatment. Electrical properties of liver tissue were measured for different temperatures. SAR distribution around the antenna into the liver are simulated using Remcom's XFDTD.

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Interpretation of Antimicrobial Susceptibility Test According to Resistance Mechanism of ${\beta}$-lactam in Enterobacteriacae (장내세균에서 ${\beta}$-lactam 항균제의 내성기전별 항균제 감수성검사의 해석)

  • Lee, Chae-Hoon
    • Journal of Yeungnam Medical Science
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    • 제27권1호
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    • pp.8-17
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    • 2010
  • It is important to select appropriate antimicrobials for the treatment of infection according to the results of antimicrobial susceptibility tests (ASTs), yet the clinical isolates are sometimes susceptible to antibiotics that are clinically ineffective or this is due to technical error of the ASTs. So, interpretive reading of ASTs is needed and especially for the ${\beta}$-lactams for treating $Enterobacteriacae$. This review describes the interpretive reading of ASTs according to natural antimicrobial resistance and the mechanisms of mechanisms, with giving special attention to the antibiotics phenotypes for $Enterobacteriacae$. Further, as all the diffent tissues have a different antimicrobial concentration for identical antimicrobials, more information is needed on the antimicrobial tissue distribution for the appropriate treatment of infection. (ED note: I hope you send me the paper.)

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The Pain of the Shoulder Joint and Posterolateral Area of Upper Arm (어깨관절과 상박부 통증에 대한 견해)

  • Kang, Yeong-Seon;Song, Chan-Woo
    • The Korean Journal of Pain
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    • 제9권1호
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    • pp.105-108
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    • 1996
  • Localized or radiating pain in the arm and shoulder joint may result after faulty alignment causing compression or tension on nerves, blood vessels, or supporting soft tissues. The critical site of faulty alignment is the quadrangular space in the axilla bounded by the teres major, teres minor, long head of triceps, and humerus. The axillary nerve emerges through this space to supply the deltoid and teres minor. The activity of the trigger point on teres minor compressing the axillary nerve causes pain to develop through the area of sensory distribution of cutaneous branch of the axillary nerve. Relieving compression on the axillary nerve and suprascapular nerve is the key point to relieving the pain. Spasm of the supraspinatus and infraspinatus compressing the suprascapular nerve caused pain to develop in the shoulder joint and scapular area. We treated those patients experiencing such pain with local anesthetic infiltration or I-R laser stimulation on the identified trigger points.

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Self-organized Nanogels of Polysaccharide Derivatives in Anti-Cancer Drug Delivery

  • Park, Sin-Jung;Na, Kun
    • Journal of Pharmaceutical Investigation
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    • 제40권4호
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    • pp.201-212
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    • 2010
  • Self-organized nanogels from polysaccharide derivatives offer a promising approach in treatment of cancer due to their flexibility in chemistry and their ability to improve the therapeutic index of a drug by modifying biodistribution by their preferential localization at target sites and lower distribution in normal healthy tissues. These properties have promoted studies of active cancer targeting by self-organized nanogels for even better accumulation in solid tumors. However although many researchers have reported their potential by using cell culture systems and small animal tumor models in cancer therapy, these nanogels need more decoration such as conjugation with targeting moiety and endowment of stimuli-sensitivity for precise targeting of the cancer site. In this review, we summarize the recent efforts in developing novel targeting approaches via active endocytosis and stimuli-sensitive systems responding to hyperthermic or acidic tumor pH conditions.

EXPERIMENTAL STUDY ON EFFECTS OF GOLD ALLOYS CROWN MARGIN IN THE RABBIT'S PERIODONTIUM (금합금관연이 가토치근막에 미치는 영향에 관한 실험적 연구)

  • Chang, Wan-Sik
    • The Journal of the Korean dental association
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    • 제9권6호
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    • pp.293-296
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    • 1971
  • Histochemical observations on the effect of gold alloys crown margin in the periodontal membrane were caried out by use of rabbits. The animal were setted with gold alloys crown on the incisor teeth. The cervical margins were given extence into gingival sockets. The animals were sacrificed at the 30 days experimented period. Specimens of tissue were obtained from the mandibular incisor teeth with jaw. All tissues were fixed immediately in 10% neutral formalin solution. Different histochemical staining methods for the determination of fibrous components were the Mallory-Heidenhain Bielschowsky-Gomori, Gomori's aldehyde fuchsin. Periodic acid-Schiff reaction and Hematoxylin eosin stanin method. The results were as follows. The periodontal membrane is composed primarily of collagenous fibers and fibrous component run functional arrangement but in lower gold content groups, horizontal fiber groups were irregularly run. Elastic fibers were obligue run in experimental groups. There were no significant differences in reticularfibers in distribution.

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Electron Microscopic Studies on Microbody of Panax ginseng (인삼(人蔘)의 Microbody에 관(關)한 전자현미경적(電子顯微鏡的) 연구(硏究))

  • Kim, Woop-Kap;Lee, Bong-Hee;Oh, Chong-Yon
    • Applied Microscopy
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    • 제2권1호
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    • pp.33-37
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    • 1972
  • The distribution, ultrastructure, and cytochemical properties of microbodies (peroxisomes) from the main roots and mature leaves of Panax ginseng were studied by electron microscopy included the activity of catalase in 3, 3'-diaminobenzidine (DAB) medium at pH 9, using glutaraldehyde-fixed tissues. The microbodies, which are about $0.5{\sim}1.5{\mu}$ diameter, were described from mesophyll cells of mature leaves and storage cells and cambial cells of main roots. The microbodies of the ginseng include the coreless, homogeneous matrix, in which catalase activities are present.

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척추동물의 Isozyme에 관한 비교연구: V. 담수어류의 젖산 수소이탈효소 Isozyme

  • 박상윤;이문성;조동현
    • The Korean Journal of Zoology
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    • 제17권3호
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    • pp.127-130
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    • 1974
  • The lactate dehydrogenase isozymes in tissues of eight fresh water fishes were examined by cellulose acetate electrophoresis. The electrophoretic distribution of the isozymes showed clearly species-specific pattern. Various subbands were found more frequently in these fishes than in mammals. The isozyme pattern of muscle seems to tend to be the same with that of brain in these fishes. The fish lactic dehydrogenase suggested in many cases to be consisted of nonrandomly selected hybrids.

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Structure and Tissue Distribution of a Trinucleotide-Repeat-containing Gene (cag-3) Expressed Specifically in the Mouse Brain

  • Ji, Jin Woo;Yang, Hye Lim;Kim, Sun Jung
    • Molecules and Cells
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    • 제20권3호
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    • pp.348-353
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    • 2005
  • Using in silico approaches and RACE we cloned a full length trinucleotide (CAG) repeat-containing cDNA (cag-3). The cDNA is 2478 bp long and the deduced polypeptide consists of 140 amino acids of which 73 are glutamines. The genomic sequence spans approximately 79 kb on mouse chromosome 7 and the gene is composed of four exons. Standard and real-time PCR analyses of several mouse tissues showed that the gene is exclusively expressed in the brain and is not detected in embryonic stages. Within the brain, it is expressed throughout the forebrain region with predominant expression in the hypothalamus and olfactory bulb and very low levels in the mid- and hindbrain.