• 한국임상수의학회지
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• 제19권2호
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• pp.115-120
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• 2002

To clarify the therapeutic effect of aquapuncture therapy on bovine foot rot, the experimental cattle were divided into control (conventional treatment), aquapuncture and combined treatment groups. Each group was composed of 6 Holstein cows with bovine foot rot. In the present study, the change in grade of lameness, total leukocyte counts, N/L. ratio, mean recovery rates (days) and histopathological changes of interdigital tissue before and after treatment were evaluated. The grade of lameness was decreased by treatment in each group, with the decreasing in order of combined > aquapuncture > control group. In change of total peripheral blood leukocyte counts, the tendency of decrease was found. Significances were detected on 9th day (P < 0.05) in control, on 6th day (P < 0.01) in aquapuncture group, and on 3rd (P < 0.05) and 6th day (P < 0.05) in combined group, respectively. In addition, significances were detected on 3rd and 6th day in aquapuncture, and on 3rd day in combined group by comparison with that of control, respectively. N/L ratio was decreased by therapy in each group with the decreasing in order of combined > aquapuncture ) control group. Significances were detected on 6th day (P < 0.01) between aquapuncture and combined groups. The mean recovery rates(days) were rapid with the decreasing in order of combined > acuapuncture > control group. In histopathological findings of interdigital tissue, the findings of inflammation and hemorrhage were not observed after treatment in each group. In conclusion, it was thought that aquapuncture and combined therapy was very effective on treatment of bovine foot rot.

• BMB Reports
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• 제47권3호
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• pp.135-140
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• 2014

The mesenchymal stem cells (MSCs), which are derived from the mesoderm, are considered as a readily available source for tissue engineering. They have multipotent differentiation capacity and can be differentiated into various cell types. Many studies have demonstrated that the MSCs identified from amniotic membrane (AM-MSCs) and amniotic fluid (AF-MSCs) are shows advantages for many reasons, including the possibility of noninvasive isolation, multipotency, self-renewal, low immunogenicity, anti-inflammatory and nontumorigenicity properties, and minimal ethical problem. The AF-MSCs and AM-MSCs may be appropriate sources of mesenchymal stem cells for regenerative medicine, as an alternative to embryonic stem cells (ESCs). Recently, regenerative treatments such as tissue engineering and cell transplantation have shown potential in clinical applications for degenerative diseases. Therefore, amnion and MSCs derived from amnion can be applied to cell therapy in neuro-degeneration diseases. In this review, we will describe the potential of AM-MSCs and AF-MSCs, with particular focus on cures for neuronal degenerative diseases.

• Physical Therapy Rehabilitation Science
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• 제2권1호
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• pp.27-30
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• 2013

Objective: Low back pain is a primary of source of dysfunction and economic costs. Gluteus medius muscle co-activation and activity pattern change caused the low back pain. Active release technique (ART) is a patented, non-invasive, soft tissue treatment process that both locates and breaks down the scar tissue and adhesions. The purpose of this study was to assess the effects on chronic low back pain using ART on gluteus medius so that suggest usable treatment method for treating chronic low back pain. Design: One group pretest-posttest design. Methods: Twelve patients with chronic low back pain were participated in this study. Subjects in ART group were received 2 times a week for 3 weeks treatments with either ART on gluteus medius muscle trigger points. Outcome measures were conducted by pain intensity with a pain visual analogue scale and pressure pain threshold on gluteus medius. Results: Completion of the intervention, the visual analogue scale was decreased in ART group (p<0.05). Also pressure pain threshold was decreased in ART group (p<0.05). Conclusions: Our results suggest that the response to ART may be usable to treat low back pain. ART was presented to reduce pain level of low back in people with chronic low back pain. Further study is required to management for low back pain due to gluteus medius and more ART study.

• BMB Reports
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• 제52권5호
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• pp.295-303
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• 2019

Breakthroughs in stem cell technology have contributed to disease modeling and drug screening via organoid technology. Organoid are defined as three-dimensional cellular aggregations derived from adult tissues or stem cells. They recapitulate the intricate pattern and functionality of the original tissue. Insulin is secreted mainly by the pancreatic ${\beta}$ cells. Large-scale production of insulin-secreting ${\beta}$ cells is crucial for diabetes therapy. Here, we provide a brief overview of organoids and focus on recent advances in protocols for the generation of pancreatic islet organoids from pancreatic tissue or pluripotent stem cells for insulin secretion. The feasibility and limitations of organoid cultures derived from stem cells for insulin production will be described. As the pancreas and gut share the same embryological origin and produce insulin, we will also discuss the possible application of gut organoids for diabetes therapy. Better understanding of the challenges associated with the current protocols for organoid culture facilitates development of scalable organoid cultures for applications in biomedicine.

• The Journal of Korean Physical Therapy
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• 제11권2호
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• pp.5-9
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• 1999

The electromagnetic agent used in physical therapy rely far their effects on tissue heating and photo reaction of the body, Infrared has a thermal and analgesic effect, Ultra violet produces direct photo chemical reaction when it interacts with the body. Laser has broad effect on medicine, Ten ding Diancibo Pu (TDP) is in the infrared ray. The wave range is 20,000-250,000, as a far infrared. The effects of the TDP are number of white and red blued cell, capacity of animal immunization activity of enzyme in the organ and blood sugar density.

• The Journal of Korean Physical Therapy
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• 제13권3호
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• pp.769-776
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• 2001

This study were to review of muscle imbalance of head, cervical and shoulder region. Head, cervical and shoulder region is a complicated mechanical unit. interconnected by numerous soft tissue links. These links, or articulation are functionaly and reflexly interdependent on one another. The line of gravity falls anterior to the transverse axis of rotation for flexion and extension of the head and creates a flexion moment. which tends to tut the head forward, is counteracted by tension in the tectorial membrane, and ligamentum nuchae, and by activity of the neck extensors. Therefore, the flexion moment equilibrate with the extension moment. Changing of the equilibrium will make mid cervical straight. It will make forward head posture(FHP) also. FHP makes imbalance of suboccipital muscles, suprahyoid muscles and infrahyoid muscles. It has some relationship with temporomandibular joint, spine and equilibrium of pelvis.

• 대한정형도수물리치료학회지
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• 제5권1호
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• pp.53-58
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• 1999

PURPOSE; The main purpose of physical therapy is to minimize patient's pain. So this study aimed at evaluating the effect of PAS release applied to tender points in reducing pain of musculoskeletal lesion persons. METHOD; The PAS (capsicum plaster) Release applied at 48 tender points to relieve and assessment pain threshold by Harold Gottlieb's pain scale that was composed of Negligible sensation 4.00, Mild sensation 3.00, Moderate sensation 2.00, Severe sensation 1.00. RESULT; Results show that PAS release was 84.6% effect in achieving a gradual decrease of pain sensitivity at the tender points where it was applied, suggestion a cumulative analgesic effect through sessions. CONCLUSION; This study suggests that PAS release applied to tender points can be effective in relieving soft tissue pain through theses have not become asymptomatic, all referred significant pain relief(p <0.05) after study and at the end of PAS release therapy.

• 대한정형도수물리치료학회지
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• 제5권1호
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• pp.17-26
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• 1999

The pelvic floor is a muscular structure, pierced by urologic, genital, and distal intestinal tract. Also pelvic floor is not a frozen but a functional unit. The pelvic floor dysfunction has 1) laxity of soft tissue and muscle 2)rupture of pelvic floor, 3)increased the tension. The purpose of this study is to give information about the pelvic floor dysfunction and pelvic exercise. This investigate the pelvic floor structure and function, pelvic floor dysfunction, pelvic floor exercise, and recent research trends. The pelvic floor exercise is one of important exercise in physical therapy, this exercise program will be improved patients with pelvic floor dysfunction.

• 대한물리치료과학회지
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• 제10권1호
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• pp.212-221
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• 2003

To observe the anatomical structures which cause a cervicogenic headache it reports, from viewpoint of physical therapist in treatment multiple to observe method which approaches, the reporter it does. With the manipulation the vertebral manipulation effected an affirmative effect to cervicogenic headache(Niels Nilsson et al,1997). The manipulation, soft the tissue massage, postural education/advice, muscular elongation, the traction, and postural exercises initially came to be used with that technique which the upper cervical vertebra(0-C3) passive accessory intervertebral movement comes to be used with a cervicogenic headache treatment technique(Grant T & Niere K., 2000). Also, it relates with the diagnosis standard about a cervicogenic headache when the body function over of the cervical vertebra is discovered, the Muscle energy technique was proposed in the treatment which is safety and effect(Bogduk N,2001). The TENS and the Mange gave a reduction effect of pain often.

• 대한후두음성언어의학회지
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• 제7권1호
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• pp.32-38
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• 1996

The preservation of the voice-producing mechanism is an important feature in the management of laryngeal cancer by radiotherapy. But, radiation therapy has certain side effects such as mucositis, tissue edema, necrosis and fibrosis which could effect on normal voice production. Several subjective studies that used questionnaires and auditory perceptual judgements of voice have been interpreted to mean that radiation results in a normal or near-normal voice. Objective evidence of the status of vocal function after radiation treatment, however, is still lacking. We analyzed the changes that occur in voice parameters in a group of patients undergoing radiation therapy, in order to determine the effect of radiation on voice quality. In this study acoustic, aerodynamic measures of vocal function were used to determine the characteristics of voice production. We found that voice parameters in early glottic cancer changed meaningfully comparing to normal larynx with or without radiation and radiation therapy has an little effect on normal larynx.