• 한국치위생학회지
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• 제19권6호
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• pp.1099-1107
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• 2019

Objectives: The purpose of this study was to investigate the changes in pH in the oral cavity using the probiotic intake method. Methods: A total of 109 participants were enrolled and randomly assigned to three groups. Participants in the control group did not ingest powdered probiotics, those in experimental group 1 ingested powdered probiotics by dissolving them on the tongue, and those in experimental group 2 dissolved powdered probiotics on the tongue and rinsed with water. pH values were measured 5 times in all. The significance of each group was examined by the Kruskal-Wallis test. The trend over time was expressed as a graph with groupwise means and confidence intervals, considering repeated measurement data. Results: A significant difference was found between the control group and experimental group 1 at two time-points, i.e., immediately after intake and 3 min after ingestion. As a result of the time trend, the pH value of experimental group 2 was smaller than that of experimental group 1, compared to the control group. Conclusions: Studies have shown that taking probiotics with water may help reduce changes in oral pH. Probiotics should be aware of live bacteria and provide consumers with more detailed information on proper dosage and precautions.

• Biomolecules & Therapeutics
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• 제30권6호
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• pp.562-569
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• 2022

Etretinate, an acitretin metabolite, has a long retention duration in adipose tissues with a teratogenic potential. FDA advises a contraceptive period of at least three years after discontinuing acitretin. However, the effect of accumulated etretinate in adipose tissues on fetus is unknown. Although the teratogenic threshold for serum concentration of etretinate has been presented as higher than 2 ng/mL, that of acitretin is unknown. To examine factors affecting body retention of acitretin and etretinate, effects of acitretin dosage, acitretin-taking duration, elapsed time after stopping acitretin, age, sex, concomitant alcohol consumption, and foods and supplements rich in vitamin A intake on serum concentrations of acitretin and etretinate were analyzed in 14 acitretin-taken patients and 58 controls without taking acitretin or etretinate. Serum concentrations of acitretin, but not etretinate, tended to be inversely related to the discontinuation duration. They were also related to old age. Different from a published result that alcohol consumption could promote the metabolism of acitretin into etretinate, alcohol intake did not affect serum concentrations of etretinate. Unexpectedly, more frequent intake of vitamin A or provitamin A-rich food and supplements was associated with higher serum acitretin, whereas less frequent intake of vitamin A or provitamin A-rich food and supplements was associated with higher serum levels of etretinate in acitretin-taken patients. Despite preliminary data, inter-individual variations in serum retention of etretinate suggest the necessity of further research before applying the same guidelines to everyone to minimize unnecessary contraception.

• 대한영양사협회학술지
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• 제7권2호
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• pp.159-166
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• 2001

This study was conducted to investigate the relationship of calcium intake , serum calcium level to calcium supplementation and the effect of nutritional education in middle-aged women. The age distribution of the subjects was 49-55 years. Daily nutrient intakes and dietary sources of calcium were analyzed by convenient method and food frequency questionnaire. At the same time, fasting blood samples were collected and serum calcium and magnesium concentrations were measured before and after nutritional education. The BMD of subjects were measured by Dual Energy X-ray Absorptiometry(DEXA). Serum calcium and magnesium concentrations were significantly(p<0.05) different between pre and post nutritional education. After nutritional education, nutrient intakes were significantly increased(p<0.05), especially calcium. This results suggested that dietary calcium intake as well as nutritional education seem to be important in preventing in middle-aged women.

• 대한핵의학회지
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• 제10권1호
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• pp.55-60
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• 1976

Marked augmentation of urinary aldosterone excretion following furosemide administration was observed in previous experiment. In this study, author measured the changes of aldosterone secretion after furosemide administration in normotensive young volunteers with high sodium intake. After intravenous injection of $1.2-^3H-aldosterone$, urine samples were collected in course of time until 24 hours after the injection. Furosemide administration was done at 30 minutes prior to aldosterone injection. Specific activities of $^3H-aldosterone$ during and after diuresis were measured and aldosterone secretion rates were calculated dividing the doses by specific activities. Results were as followed 1. Furosemide resulted in a marked increase in urinary aldosterone excretion. 2. Furosemide lead to an increase in both sodium and potassium excretion. 3. Aldosterone secretion rate was also increased during furosemide diuresis, but the rate was smaller than that of urinary excretion. 4. Continuous modest increase in aldosterone secretion rate was shown after diuresis and total excess amount of aldosterone secretion for 24 hrs was equivalent to the amount of aldosterone excretion produced by diruesis. 5. Abrupt marked loss of circulating aldosterone produced by diuresis was supplemented by long lasting increase in secretion for over twenty four hours.

• 한국생활과학회지
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• 제12권2호
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• pp.265-273
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• 2003

The aim of this study was to investigate the effect d concentrated fermented milk on the improvement of defecation in female students with constipation. This yogurt was fermented with Bifidobacterium, L. acidophilus, and S. thermophilus and supplemented with oligosaccharides, dietary fiber, and yeast and mushroom extracts. 44 female students with constipation were sampled as subjects and fed 150ml fermented milk per day for 2 weeks period. After each defecation, the subjects were examined for the status of stool evacuation by questionnaires. The frequency of stool evacuation, fecal amount, time spending for evacuation, fecal color and shape, and refreshing feeling after evacuation were remarkably improved after ingestion of fermented milk for 2 weeks. These effects were greater in the heavy constipation group than in the mild group. The fecal odor did rot decrease significantly after 2 weeks of intake of fermented milk, but the odor thended to decrease after the intake of fermented milk These results indicated that the ingestion of concentrated fermented milk is effective to improve the constipation.

• 여성건강간호학회지
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• 제29권1호
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• pp.66-75
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• 2023

Purpose: Supportive interventions to improve breastfeeding practice are needed in nursing. This study investigated the effects of pectoralis major myofascial release massage (MRM) on breast pain and engorgement among breastfeeding mothers and on breast milk intake and sleep patterns among newborns. Methods: Breastfeeding mothers who had delivered between 37 and 43 weeks and had 7-to 14-day-old newborns were recruited from a postpartum care center in Gunpo, Korea. Participants were randomized to the MRM or control group. The outcome variables were breast pain and breast engorgement among breastfeeding mothers and breast milk intake and sleep time among newborns. The experimental treatment involved applying MRM to separate the pectoralis major muscle and the underlying breast tissue in the chest. After delivery, the first MRM session (MRM I) was provided by a breast specialist nurse, and the second (MRM II) was administered 48 hours after MRM I. Results: Following MRM, breast pain (MRM I: t=-5.38, p<.001; MRM II: t=-10.05, p<.001), breast engorgement (MRM I: right, t=-1.68, p =.100; left, t=-2.13, p=.037 and MRM II: right, t=-4.50, p<.001; left, t=-3.74, p<.001), and newborn breast milk intake (MRM I: t=3.10, p=.003; MRM II: t=3.09, p=.003) differed significantly between the groups. Conclusion: MRM effectively reduced breast engorgement and breast pain in breastfeeding mothers, reducing the need for formula supplementation, and increasing newborns' breast milk intake. Therefore, MRM can be utilized as an effective nursing intervention to alleviate discomfort during breastfeeding and to improve the rate of breastfeeding practice (clinical trial number: KCT0002436).

• Preventive Nutrition and Food Science
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• 제10권2호
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• pp.179-186
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• 2005

This study was conducted to find the gender and age differences in dietary behaviors and food consumption pattern of Korean American adults living in western parts of USA. The structured survey forms and self-administered food frequency questionnaire were used to assess dietary behavior and nutrient intakes. It was found that younger subjects kept their meal time more irregularly and skipped breakfast more often than older subjects due to lack of time. There were significant age differences in skipping meals, kind of skipping meals, and the reasons for skipping meals. Young subjects consumed more American type food while older subjects consumed more traditional Korean food. Nutrient intakes of males' except for the elderly were significantly higher in energy, protein, Fe and P than those of females'. Vitamin A and vitamin C intake were significantly higher in females. Energy ratio of carbohydrate: protein: fat was 56.2 : 16.8 : 27.0. Females consumed more plant food as their dietary sources of protein, fat, Ca and Fe, compared to males. Ca intakes of participants' were below $75\%$ of RDA except for the youngest male and $30\~49$ aged male and females. Futhermore, Ca intake was below $70\%$ after age 50 in both genders. Effective nutrition education program targeting Korean Americans in the community should be developed and implemented to increase Ca consumption.

• The Korean Journal of Physiology
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• 제2권1호
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• pp.73-78
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• 1968

The changes of urinary excretion after alcohol drinking on 6 normal subjects sweated in a hot chamber were studied. The results are summarized as follows: 1. The urinary minute flow is increased rapidly to maximum about 60 minutes after intake of alcohol, and this is supposed to be originated from the antidiuretic suppressive action on osmoreceptor by ethyl alcohol. 2. Free water clearance and osmolarity of the urine showed the maximal and minimal values respectively at the sane time when the urinary flow is maximal. 3. The concentrations of Na, K and Cl were roughly proportionate to the urinary osmolarity and the minimal values after drinking were diluted to more than 10-fold than those before drinking, but the minute amounts of these ions is decreased only slightly during tile diuresis. 4. The concentrations of urea were decreased less than 10-fold but the minute amounts were rather increased slightly. 5. The diuresis could not excrete whole quantity of fluid intake in the period of 2 hours, and considerable amount of water was still retained in the body.

• 한국가시화정보학회지
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• 제9권4호
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• pp.74-79
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• 2011

In this study the change of free surface vortex is represented at different times according to height of water and with or without curtain wall installation. The air volume fraction is investigated at each condition of water level and the influence about creation of vortex is analyzed. The height of sump intake is taken as 100mm and the water level is divided into 5 steps. The sump model is the TSJ model and the curtain wall is applied by HI standard of America. The results shows that the free surface vortex can be identified on the isotropic surface at air volume fraction 1%~5% and the vortices make an air column from the free surface to the sump intake and are created and destroyed repeatedly. In the higher water level, less air is absorbed into the intake pipe. After curtain wall installation, the suction rate of the air volume fraction is decreased by 6.7%. The result of the vortex motion according to time, works on a cycle.

• Journal of Advanced Marine Engineering and Technology
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• 제32권8호
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• pp.1141-1148
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• 2008

One of the methods to increase the efficiency of an engine is to expand pressures obtained from combustions equal to the pressure of atmosphere as much as possible and then convert thermal energy into mechanical energy also as much as possible. In this research, the Diesel cycle was thermodynamically interpreted to evaluate the possibility of high efficiency by converting Diesel engines to the Atkinson cycle, and general cycle features were analyzed after comparing these two cycles. In the case of fuel air the Diesel-Atkinson cycle considering intake and exhaust similar to real cycles, the value of thermal efficiency and average effective pressure increased, though their values were smaller than those of standard air amount cycle, when expansion compression ratio increased. When normal Diesel engines of which compression stroke and expansion stroke are all the same, was converted to the Atkinson cycle by changing the time of intake value close, combustion pressure reduced due to reduced expansion compression ratio and intake air amount due to decreased effective cycle volume.