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Assessment of mulberry leaf as a potential feed supplement for animal feeding in P.R. China

  • Cai, Ming;Mu, Lan;Wang, Zong-li;Liu, Jian-yong;Liu, Tian-liang;Wanapat, Metha;Huang, Bi-zhi
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.8
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    • pp.1145-1152
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    • 2019
  • Objective: Mulberry (Morus alba L.) is a cultivated shrub grown widely in the sub-tropical and tropical areas. It has been shown that mulberry leaf contains high levels of protein while having polyphenols as phytonutrients. Therefore, it is important to conduct an experiment to assess potential toxic level from mulberry on behavior, blood hematological and coagulation parameter using Sprague-Dawley (SD) rats. Methods: Both male and female SD rats were given an intragastric administration of respective treatments of mulberry leaf intakes (control, low and high levels). Parameters of feed intake, hematological and coagulation of blood parameters, as well as liveweight changes were taken during the 7 d of adaptation, 28 d of treatment exposure, and 14 d of recovery periods, respectively. All treatment data were statistically analyzed using analysis of variance of SPSS17.0 for Windows Statistical Software following the Randomized complete block design with sex as a block. Results: Most of the parameters of the physical symptoms of the SD rats, were not significantly different (p>0.05) when compared with that of the control group. Those which remain unchanged in each dose group were, body weight (BW) gain, feed intake, the hematology and coagulation indexes. Although, there were a few individual indicators that were abnormal, but the overall physiological appearance of the rats were normal. Conclusion: Results under this experiment revealed that most hematological and coagulation parameters of the SD rats in both male and female were normal, although the weight gain of female rats in high-dose group was significantly reduced than those of the male rats. Under this study, the use of mulberry leaf up to 2 g/kg BW did not result in abnormal phenomenon in the SD rats. These findings would offer useful information for further in vivo feeding trials in animals to extensively use of mulberry leaf to improve animal production, particularly in P.R. China.

A comparative study on the 'Xuan'in the view of Yangxiong & Gehong(2) (양웅(揚雄)과 갈홍(葛洪)의 '현(玄)' 개념 비교 연구(2) - 우주구조론을 중심으로 -)

  • Lee, Jin-yong
    • The Journal of Korean Philosophical History
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    • no.42
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    • pp.165-195
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    • 2014
  • This paper aims to examine the meaning of 'Xuan(玄)' in the cosmology and astronomy, especially in the view of Yang-xiong(揚雄) and Ge-hong(葛洪). The cosmology of the ancient China has opened a discussion about the Tian(天), through the discussion about the celestial structure, the structure and the location relation of the heaven & earth, in the Han-dynasty has been found a systematic theory. But in the ancient Chinese philosophy, the cosmology has been developed in the field of the astronomy & the Oriental calendar. In this context, Yang-xiong(揚雄) and Ge-hong(葛洪) have founded the system of the cosmology, it is as in the following. First, Yang-xiong criticized sharply the theory of Gaitian(蓋天說) and advanced the theory of Huntian(渾天說). And Ge-hong support the theory of Huntian(渾天說) and also accepted the theory of Xuanye(宣夜說). Second, Yang-xiong(揚雄) and Ge-hong(葛洪)'s cosmology is regarded as the theoretical premise of their cosmogony. As the discussion about the celestial structure, the structure and the location relation of the heaven & earth, both scholar discussed about the cause of creation, the differentiation process. And in the this context, they founded the cosmology as the concept 'Xuan'. Third, the concept 'Xuan' in the both scholar forms a philosophical system. Yang-xiong insisted that the concept 'Xuan' is the basis of the universe, the human-being and the society. While through realizing the concept 'Xuan', Ge-hong tried to pursue the human-being's agelessness and the eternal life. In this way, their view point of the cosmology is comprised of cosmogony & astronomy. With this perspective, they are going to found the system of their own philosophy.

Research on the Soul & Body Thought of Chinese Six Dynasties thinker (육조시기(六朝時期) 사상가들의 육체(肉體)와 영혼(靈魂)의 관념에 대한 개략적 고찰)

  • Cho, Won-il
    • (The)Study of the Eastern Classic
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    • no.59
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    • pp.387-404
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    • 2015
  • A great number of philosophers during 'Six's Dynasty'(六朝) had the most active and furthest discussion throughout the history of China to study the concerns; Having a question such as "Where the body and the soul come out around us?", "What is the essence of complicated and delicate mental operation?" "Are there any relationships between the body and the soul?" and then "How do the human soul exist after death?" First, during 'Don-Jin' period as body and soul theory was based on 'Yin'(陰) and 'Yang'(陽). 'He Cheng Tian' said that everything which was burn on earth should die because the soul couldn't stay the dead body longer. In the same age, 'Ming Fo Run' and 'Da Xing Run' which denied that the soul couldn't exist forever were main topics of the discuss among the distinguished philosophers. Next, during 'Northern & Southern dynasty', body and soul theory was divided into two. First of all, body and soul of 'Heng Cun' might be harmonized, however, that was not perfectly put together. Because, after human death, even if the body of human might be existed, the soul left elsewhere but always stayed around us. The body was the soul which meant that the soul was to the nature of the body and the body was to the usage of soul. Many philosophers insisted that nobody meant no soul according to 'Shen Bu Mie Run' and 'Shen Mie Run'which was the main topic as an academic argument in those days. Finally, during Dong-Jin dynasty covered the significance of Body and Soul theory and analyzed the influence into the history of the history philosophy in china.

A Study on the Characteristics of Disaster Temporary Sheltering in Terms of Sustainable Design -Focused on the Case of the Wenchuan Earthquake in Sichuan Province- (지속가능성 측면에서 재난 임시대피소의 특성 연구 -쓰촨성(四川省) 원촨(汶川) 지진 사례를 중심으로-)

  • Tian, Hui;Yoon, Ji-Young;Wang, Dan
    • The Journal of the Korea Contents Association
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    • v.21 no.5
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    • pp.877-888
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    • 2021
  • This study used three types of temporary shelters, tents, and prefabricated houses provided by the Chinese government for victims after the Wenchuan earthquake in 2008 as case study objects. Through literature review, 12 evaluation items were selected from the social, economic, and environmental elements of the sustainability of residential space design to analyze and evaluate three types of temporary shelters, and derive their respective characteristics and problems. The analysis results show that the temporary centralized settlements and tents had problems such as imperfect infrastructure, poor sanitation, narrow living space, no personal space, and inconvenience in life. Prefabricated houses had problems such as high construction costs, non-environmentally friendly building materials, occupation of arable land, low recycling rate of materials, and environmental pollution by waste. The common problem of the three types of shelters was that the government took the lead in the construction and distribution of shelters, and the disaster victims passively accept government support. Therefore, disaster victims were not actively involved in the construction and management of temporary communities. Secondly, the designs of all three types of temporary shelters did not fully consider the psychological needs of the victims, especially the need for safe and hygienic personal space. Finally, this research proposes improvement plans for the problems in the sustainable design of three temporary shelters and the construction and management of temporary communities.

On an Application of the Sound Massage for Safe Wet Shaving (안전한 습식면도를 위한 소리마사지 적용 연구)

  • Tian, Zhixing;Bae, Myung-Jin
    • The Journal of the Convergence on Culture Technology
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    • v.8 no.1
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    • pp.605-609
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    • 2022
  • Shaving for adult men is one of the essential requirements for life. For physiological reasons, most adult men have beards, and if men trim their beards and take good care of them, their appearance becomes cleaner. If a dull blade is used for a wet razor, or if an appropriate massage is not used, skin irritation may occur, resulting in shaving wounds. Therefore, the convenience and comfort of the razor are required as much as the skin becomes smooth after shaving. In this paper, a pre-shaving method of sound massage was proposed to reduce the irritation of wet shaving on the skin and increase the convenience of shaving. It softens the skin or secretes oil through non-face-to-face low-frequency speakers to increase skin gloss, making shaving smooth and safe. We recorded the sound of the wet shave state to determine the skin condition before and after the wet shave, and objectively compared and analyzed the effect with this sound spectrum. In other words, it can be seen from the experimental results that the sound massage before shaving reduces the friction between the razor and the skin and the skin and beard by -7.0 dB, improving the skin wound of the wet shave and achieving a refreshing shave.

On a Cleaning of COVID-19 Prevention Masks with Electrolytic Decomposition Water (전기분해수로 코로나방역용 마스크의 세정에 관한연구)

  • Tian, Zhixing;Bae, Myung-Jin
    • The Journal of the Convergence on Culture Technology
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    • v.8 no.1
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    • pp.591-596
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    • 2022
  • Various COVID-19 quarantine guidelines and measures are being taken by country at the WHO, but the number of confirmed cases has not decreased significantly. In order to prevent the inflow and outflow of COVID-19 through individual droplets, it is mandatory to wear a mask anytime, anywhere. However, as virus bacteria entering the mask amplify, it pollutes the mask and causes a disgusting smell. In this paper, a new method of preventing the spread of COVID-19 was proposed by sterilizing the mask with a dental gait spray introduced into the mask that has been used for a long time. Dental gargle water is usually produced by electrolysis of tap water, and the unstable ion water (HOCl) dissolved in water penetrates the cell barrier of various viruses and fails to act in its nucleus, causing water to self-purify. As a result of the experiment, when the mask used for a long time was washed with gargle water spray, the washed mask was dried after 10 minutes, and the smell of virus droplets or saliva almost disappeared. In particular, as a result of MOS testing the fit of the subjects who participated in the mask cleaning, it was excellent at 4.4 on average. Therefore, the mask was disposable, but if the spray was washed in the proposed method more than twice a day, the mask could be used in a comfortable state for more than a week.

Molecular dynamics study of liquid sodium film evaporation and condensation by Lennard-Jones potential

  • Wang, Zetao;Guo, Kailun;Wang, Chenglong;Zhang, Dalin;Tian, Wenxi;Qiu, Suizheng;Su, Guanghui
    • Nuclear Engineering and Technology
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    • v.54 no.8
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    • pp.3117-3129
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    • 2022
  • Deeply understanding the phase change of thin liquid sodium film inside wick pore is very important for further studying high-temperature sodium heat pipe's heat transfer. For the first time, the evaporation and condensation of thin liquid sodium film are investigated by the Lennard-Jones potential of molecular dynamics. Based on the startup and normal operation of the sodium heat pipe, three different cases are simulated. First, the equilibrium is achieved and the Mass Accommodation Coefficients of the three cases are 0.3886, 0.2119, 0.2615 respectively. Secondly, the non-equilibrium is built. The change of liquid film thickness, the number of gas atoms, the net evaporation flux (Jnet), the heat transfer coefficient (h) at the liquid-gas interface are acquired. Results indicate that the magnitude of the Jnet and the h increase with the basic equilibrium temperature. In 520-600 K (the startup of the heat pipe), the h has approached 5-6 W m-2 K-1 while liquid film thickness is in 11-13 nm. The fact shows that during the initial startup of the sodium heat pipe, the thermal resistance at the liquid-gas interface can't be negligible. This work is the complement and extension for macroscopic investigation of heat transfer inside sodium heat pipe. It can provide a reference for further numerical simulation and optimal design of the sodium heat pipe in the future.

Numerical analysis of melt migration and solidification behavior in LBR severe accident with MPS method

  • Wang, Jinshun;Cai, Qinghang;Chen, Ronghua;Xiao, Xinkun;Li, Yonglin;Tian, Wenxi;Qiu, Suizheng;Su, G.H.
    • Nuclear Engineering and Technology
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    • v.54 no.1
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    • pp.162-176
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    • 2022
  • In Lead-based reactor (LBR) severe accident, the meltdown and migration inside the reactor core will lead to fuel fragment concentration, which may further cause re-criticality and even core disintegration. Accurately predicting the migration and solidification behavior of melt in LBR severe accidents is of prime importance for safety analysis of LBR. In this study, the Moving Particle Semi-implicit (MPS) method is validated and used to simulate the migration and solidification behavior. Two main surface tension models are validated and compared. Meanwhile, the MPS method is validated by the L-plate solidification test. Based on the improved MPS method, the migration and solidification behavior of melt in LBR severe accident was studied furthermore. In the Pb-Bi coolant, the melt flows upward due to density difference. The migration and solidification behavior are greatly affected by the surface tension and viscous resistance varying with enthalpy. The whole movement process can be divided into three stages depending on the change in velocity. The heat transfer of core melt is determined jointly by two heat transfer modes: flow heat transfer and solid conductivity. Generally, the research results indicate that the MPS method has unique advantage in studying the migration and solidification behavior in LBR severe accident.

Thermal-hydraulic research on rod bundle in the LBE fast reactor with grid spacer

  • Liu, Jie;Song, Ping;Zhang, Dalin;Wang, Shibao;Lin, Chao;Liu, Yapeng;Zhou, Lei;Wang, Chenglong;Tian, Wenxi;Qiu, Suizheng;Su, G.H.
    • Nuclear Engineering and Technology
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    • v.54 no.7
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    • pp.2728-2735
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    • 2022
  • The research on the flow and heat transfer characteristics of lead bismuth(LBE) is significant for the thermal-hydraulic calculation, safety analysis and practical application of lead-based fast reactors(LFR). In this paper, a new CFD model is proposed to solve the thermal-hydraulic analysis of LBE. The model includes two parts: turbulent model and turbulent Prandtl, which are the important factors for LBE. In order to find the best model, the experiment data and design of 19-pin hexagonal rod bundle with spacer grid, undertaken at the Karlsruhe Liquid Metal Laboratory (KALLA) are used for CFD calculation. Furthermore, the turbulent model includes SST k - 𝜔 and k - 𝜀; the turbulent Prandtl includes Cheng-Tak and constant (Prt =1.5,2.0,2.5,3.0). Among them, the combination between SST k - 𝜔 and Cheng-Tak is more suitable for the experiment. But in the low Pe region, the deviation between the experiment data and CFD result is too much. The reason may be the inlet-effect and when Pe is in a low level, the number of molecular thermal diffusion occupies an absolute advantage, and the buoyancy will enhance. In order to test and verify versatility of the model, the NCCL performed by the Nuclear Thermal-hydraulic Laboratory (Nuthel) of Xi'an Jiao tong University is used for CFD to calculate. This paper provides two verification examples for the new universal model.

Compound K attenuates hyperglycemia by enhancing glucagon-like peptide-1 secretion through activating TGR5 via the remodeling of gut microbiota and bile acid metabolism

  • Tian, Fengyuan;Huang, Shuo;Xu, Wangda;Chen, Lan;Su, Jianming;Ni, Haixiang;Feng, Xiaohong;Chen, Jie;Wang, Xi;Huang, Qi
    • Journal of Ginseng Research
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    • v.46 no.6
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    • pp.780-789
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    • 2022
  • Background: Incretin impairment, characterized by insufficient secretion of L-cell-derived glucagon-like peptide-1 (GLP-1), is a defining step of type 2 diabetes mellitus (T2DM). Ginsenoside compound K (CK) can stimulate GLP-1 secretion; however, the potential mechanism underlying this effect has not been established. Methods: CK (40 mg/kg) was administered orally to male db/db mice for 4 weeks. The body weight, oral glucose tolerance, GLP-1 secretion, gut microbiota sequencing, bile acid (BA) profiles, and BA synthesis markers of each subject were then analyzed. Moreover, TGR5 expression was evaluated by immunoblotting and immunofluorescence, and L-cell lineage markers involved in L-cell abundance were analyzed. Results: CK ameliorated obesity and impaired glucose tolerance in db/db mice by altering the gut microbiota, especially Ruminococcaceae family, and this changed microbe was positively correlated with secondary BA synthesis. Additionally, CK treatment resulted in the up-regulation of CYP7B1 and CYP27A1 and the down-regulation of CYP8B1, thereby shifting BA biosynthesis from the classical pathway to the alternative pathway. CK altered the BA pool by mainly increasing LCA and DCA. Furthermore, CK induced L-cell number expansion leading to enhanced GLP-1 release through TGR5 activation. These increases were supported by the upregulation of genes governing GLP-1 secretion and L-cell differentiation. Conclusions: The results indicate that CK improves glucose homeostasis by increasing L-cell numbers, which enhances GLP-1 release through a mechanism partially mediated by the gut microbiota-BA-TGR5 pathway. Therefore, that therapeutic attempts with CK might be useful for patients with T2DM.