• Genomics & Informatics
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• 제6권1호
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• pp.18-28
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• 2008

Single nucleotide polymorphisms (SNPs) are the most abundant forms of human genetic variations and resources for mapping complex genetic traits and disease association studies. We have constructed a linkage disequilibrium (LD) map of chromosome 22 in Korean samples and compared it with those of other populations, including Yorubans in Ibadan, Nigeria (YRI), Centre d'Etude du Polymorphisme Humain (CEPH) reference families (CEU), Japanese in Tokyo (JPT) and Han Chinese in Beijing (CHB) in the HapMap database. We genotyped 4681 of 111,448 publicly available SNPs in 90 unrelated Koreans. Among genotyped SNPs, 4167 were polymorphic. Three hundred and five LD blocks were constructed to make up 18.6% (6.4 of 34.5 Mb) of chromosome 22 with 757 tagSNPs and 815 haplotypes (frequency $\geq$ 5.0%). Of 3430 common SNPs genotyped in all five populations, 514 were monomorphic in Koreans. The CHB + JPT samples have more than a 72% overlap with the monomorphic SNPs in Koreans, while the CEU + YRI samples have less than a 38% overlap. The patterns of hot spots and LD blocks were dispersed throughout chromosome 22, with some common blocks among populations, highly concordant between the three Asian samples. Analysis of the distribution of chimpanzee-derived allele frequency (DAF), a measure of genetic differentiation, Fst levels, and allele frequency difference (AFD) among Koreans and the HapMap samples showed a strong correlation between the Asians, while the CEU and YRI samples showed a very weak correlation with Korean samples. Relative distance as a quantitative measurement based upon DAF, Fst, and AFD indicated that all three Asian samples are very proximate, while CEU and YRI are significantly remote from the Asian samples. Comparative genome-wide LD studies provide useful information on the association studies of complex diseases.

• Earthquakes and Structures
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• 제17권6호
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• pp.623-633
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• 2019

A large number of available concrete buildings designed only considering gravity load that require seismic rehabilitation because of failure to meet plasticity criteria. Using steel bracings are a common type of seismic rehabilitation. The eccentric bracings with vertical link reduce non-elastic deformation imposed on concrete members as well as elimination of probable buckling problems of bracings. In this study, three concrete frames of 10, 15, and 20 stories designed only for gravity load have been considered for seismic improvement using performance-based plastic design. Afterwards, nonlinear time series analysis was employed to evaluate seismic behavior of the models in two modes including before and after rehabilitation. The results revealed that shear link can yield desirable performance with the least time, cost and number of bracings of concrete frames. Also, it was found that the seismic rehabilitation can reduce maximum relative displacement in the middle stories about 40 to 80 percent. Generally, findings of this study demonstrated that the eccentric bracing with vertical link can be employed as a suitable proxy to achieve better seismic performance for existing high rise concrete frames.

• 반도체디스플레이기술학회지
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• 제19권1호
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• pp.42-48
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• 2020

As global warming accelerates, eco-friendly electric cars are being developed to reduce carbon dioxide emissions, and power conversion inverters are used to drive motors. Among inverter components, DC-link capacitor is heated by high current usage, which causes problems such as performance and life-saving of inverter. Although metal cases with good thermal performance have been used to solve this problem, it is difficult to apply them in practice due to insulation problems with other parts. In this paper, the Heat-Generation influence factor of DC-link capacitor is analyzed. Variables on heat-generation are set at 3 levels for film width, inductance, and film thickness. Box-Behnken to 13 tests using the design and minimal deviations, e.g. through the experiment three times by each level. The surface of the film k type by attaching the sensor current is measured temperature. Capacitance was set to a minimum level of 200 ㎌ and had a frequency of 16 kHz with Worst case, ambient temperature of 85℃ and a ripple current of 50 Ams was applied. The temperature at the measurement point was collected in the data logger after sampling at 1 minute intervals for 2 hours after saturation with the ambient temperature. This experiment confirmed that setup factors are correlated with heat-generation.

• Geomechanics and Engineering
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• 제25권2호
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• pp.135-142
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• 2021

This study provided a new research perspective for processing and analyzing AE data to evaluate rock failure. Cluster method and information entropy theory were introduced to investigate temporal and spatial correlation of acoustic emission (AE) events during the rock failure process. Laboratory experiments of granite subjected to compression were carried out, accompanied by real-time acoustic emission monitoring. The cumulative length and dip angle curves of single links were fitted by different distribution models and distribution functions of link length and directionality were determined. Spatial scale and directionality of AE event distribution, which are characterized by two parameters, i.e., spatial correlation length and spatial correlation directionality, were studied with the normalized applied stress. The entropies of link length and link directionality were also discussed. The results show that the distribution of accumulative link length and directionality obeys Weibull distribution. Spatial correlation length shows an upward trend preceding rock failure, while there are no remarkable upward or downward trends in spatial correlation directionality. There are obvious downward trends in entropies of link length and directionality. This research could enrich mathematical methods for processing AE data and facilitate the early-warning of rock failure-related geological disasters.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제10권7호
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• pp.3131-3149
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• 2016

In-band Full-duplex (IBFD) wireless communication allows improved throughput for wireless networks. The current Half-duplex (HD) medium access mechanism Request to Send/Clear to Send (RTS/CTS) has been directly applied to IBFD wireless networks. However, this is only able to support a symmetric dual link, and does not provide the full advantages of IBFD. To increase network throughput in a superior way to the HD mechanism, a novel three-way handshaking access mechanism RTS/SRTS (Second Request to Send)/CTS is proposed for point to multipoint (PMP) IBFD wireless networks, which can support both symmetric dual link and asymmetric dual link communication. In this approach, IBFD wireless communication only requires one channel access for two-way simultaneous packet transmissions. We first describe the RTS/SRTS/CTS mechanism and the symmetric/asymmetric dual link transmission procedure and then provide a theoretical analysis of network throughput and delay using a Markov model. Using simulations, we demonstrate that the RTS/SRTS/CTS access mechanism shows improved performance relative to that of the RTS/CTS HD access mechanism.

• KCI Concrete Journal
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• 제13권2호
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• pp.67-74
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• 2001

In this study, a numerical model for the simulation of reinforced concrete columns subject to cyclic loading is presented. The model consists of three separate models representing concrete, reinforcing steel bars and bond-slip between a reinforcing bar and ambient concrete. The concrete model is represented by the plane stress plastic-damage model and quadrilateral finite elements. The nonlinear steel bar model embedded in truss elements is used for longitudinal and transverse reinforcing bars. Bond-slip mechanism between a reinforcing bar and ambient concrete is discretized using connection elements in which the hysteretic bond-slip link model defines the bond stress and slip displacement relation. The three models are connected in finite element mesh to represent a reinforced concrete structure. From the numerical simulation, it is shown that the proposed model effectively and realistically represents the overall cyclic behavior of a reinforced concrete column. The present plastic-damage concrete model is observed to work appropriately with the steel bar and bond-slip link models in representing the complicated localization behavior.

• Journal of Electrical Engineering and Technology
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• 제8권4호
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• pp.951-958
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• 2013

This paper proposes the controller design for a stability improvement of an on-board battery charger. The system is comprised of a power factor correction (PFC) circuit and phase shift full-bridge DC-DC converter. The PFC circuit performs the control of the DC-link voltage and the input power factor. The DC-DC converter regulates the voltage and the current in the battery using the DC-link voltage. This paper proposes the design method of PI controller for the PFC circuit using a small signal model. The analysis and design of a type-three controller for the DC-DC converter is also presented. A simulation and experiment has been performed on the on-board battery charger and their results are presented to verify the validity of the proposed system.

• Journal of Power Electronics
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• 제15권6호
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• pp.1421-1428
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• 2015

The efficiency and reliability of the dual-buck inverter (DBI) were greatly improved by eliminating the shoot-through problem and optimally designing the freewheeling diode. The traditional DBI suffers from large harmonic components with low output voltage and large capacity output filter inductor. To overcome the aforementioned disadvantages, a modified DBI (MBDI) was proposed by adopting a quasi-resonant link and pulse density modulation (PDM). This paper first introduces the working principle of the MBDI and PDM, and then the selection principle of system parameters is presented. Finally, a mathematical model of the MBDIis built, and an experiment prototype is set up. Simulation and experimental results verify the correctness of the theoretical analysis and the feasibility of the scheme.

• 산업기술연구
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• 제15권
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• pp.137-146
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• 1995

The reference model for UNI (User Network Interface) of B-ISDN is consisted of three function groups (B-NTI, B-NT2 and B-TE). In this study, we constructed passive B-NT1 module which can be utilized for optical link management and repair, one of main functions of B-NT1. For the convenience of installation and management, this module is only consisted of passive optical devices. And at a local exchange center linked with the module, the broken zone of optic link is able to be monitored without interrupting services. In addition, we performed the power burget analysis for the design of efficient optic link including this module.

• International Journal of Control, Automation, and Systems
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• 제6권2호
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• pp.223-233
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• 2008

A new output feedback controller design approach for flexible-joint (FJ) robots via the observer dynamic surface design technique is presented. The proposed approach only requires the feedback of position states. We first design an observer to estimate the link and actuator velocity information. Then, the link position tracking controller using the observer dynamic surface design procedure is developed. Therefore, the proposed controller can be simpler than the observer backstepping controller. From the Lyapunov stability analysis, it is shown that all signals in a closed-loop system are uniformly ultimately bounded. Finally, the simulation results of a three-link FJ robot are presented to validate the good position tracking performance of the proposed control system.