• 한국가족관계학회지
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• 제22권2호
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• pp.3-25
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• 2017

Objective: The purpose of this study was to examine the reliability and validity of the Korean version of the Helicopter Parenting Scale (HPS) using a sample of Korean young adults aged 19-34. This study is to expand the previous validation studies that exclusively focused on college students. Method: The survey data came from 1,140 young adults (398 19-24 year olds, 376 25-29 year olds, and 366 30-34 year olds) who had never been married and had at least one living parent. The young adults' perceived helicopter parenting was assessed by 10 items of the HPS for the mother and the father separately. All of the analyses including exploratory and confirmatory factor analyses were conducted for three age groups (19-24, 25-29, and 30-34 years) and for the mother and the father separately. Results: We found that three items were problematic for all age groups and for both the fathers' and mothers' helicopter parenting. After removing these three items, confirmatory factor analyses showed that the one-factor model fit our data well and the estimated factor loadings were suitable. The results were consistent throughout the age groups and the parent's gender. We also confirmed criterion-related validity using correlations between paternal and maternal helicopter parenting and three dimensions of parental career expectations indicated a reliable. Conclusion: The Korean version of HPS with seven items was found to be a reliable and valid measure for Korean young adults aged 19-34 years old.

• Asian Pacific Journal of Cancer Prevention
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• 제13권3호
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• pp.1059-1063
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• 2012

Objective: Angiogenesis represents a key element in the pathogenesis of malignancy. There are no robust data on prognostic factors for overall survival (OS) in patients with metastatic colorectal cancer treated with vascular endothelial growth factor (VEGF)-targeted therapy. The present study was conducted to establish a prognostic model for patients using an oxaliplatin-based or irinotecan-based chemotherapy plus bevacizumab in metastatic colorectal cancer. Methods: Baseline characteristics and outcomes on 170 patients treated with FOLFIRI or XELOX plus anti-VEGF therapy-naive metastatic colorectal cancer were collected from three Turkey cancer centers. Cox proportional hazards regression was used to identify independent prognostic factors for OS. Results: The median OS for the whole cohort was 19 months (95% CI, 14.3 to 23.6 months). Three of the seven adverse prognostic factors according to the Anatolian Society of Medical Oncology (ASMO) were independent predictors of short survival: serum lactate dehydrogenase (LDH) greater than the upper limit of normal (ULN; p<0.001); neutrophils greater than the ULN (p<0.0014); and progression free survival (PFS) less than 6 months (p =0.001). Conclusion: Serum LDH and neutrophil levels were the main prognostic factors in predicting survival, followed by PFS. This model validates incorporation of components of the ASMO model into patient care and clinical trials that use VEGF-targeting agents.

• Journal of Ginseng Research
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• 제43권4호
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• pp.550-561
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• 2019

Background: Gastric ulcer (GU) is a common gastrointestinal disease that can be induced by many factors. Finding an effective treatment method that contains fewer side effects is important. 20 (S)-ginsenoside Rg3 is a kind of protopanaxadiol and has shown superior antiinflammatory and antioxidant effects in many studies, especially cancer studies. In this study, we examined the treatment efficacy of 20 (S)-ginsenoside Rg3 on GU. Methods: Three kinds of GU models, including an alcohol GU model, a pylorus-ligated GU model, and an acetic acid GU model, were used. Mouse endothelin-1 (ET-1) and nitric oxide (NO) levels in blood and epidermal growth factor (EGF), superoxide dismutase, and NO levels in gastric mucosa were evaluated. Hematoxylin and eosin staining of gastric mucosa and immunohistochemical staining of ET-1, inducible nitric oxide synthase (NOS2), and epidermal growth factor receptors were studied. Ulcer index (UI) scores and UI ratios were also analyzed to demonstrate the GU conditions in different groups. Furthermore, Glide XP from $Schr{\ddot{o}}dinger$ was used for molecular docking to clarify the interactions between 20 (S)-ginsenoside Rg3 and EGF and NOS2. Results: 20 (S)-ginsenoside Rg3 significantly decreased the UI scores and UI ratios in all the three GU models, and it demonstrated antiulcer effects by decreasing the ET-1 and NOS2 levels and increasing the NO, superoxide dismutase, EGF, and epidermal growth factor receptor levels. In addition, high-dose 20 (S)-ginsenoside Rg3 showed satisfactory gastric mucosa protection effects. Conclusion: 20 (S)-ginsenoside Rg3 can inhibit the formation of GU and may be a potential therapeutic agent for GU.

• Journal of Information Technology Applications and Management
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• 제20권3_spc호
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• pp.259-278
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• 2013

At the center of the repeating evolution of IT industry, there is mobile computing in the ubiquitous environment, and the increasing usage of smart phones contribute more to its growth. P corporation co-developed with Google and implemented smart work system called SWP for the purpose of 'communication and collaboration with co-workers' beyond the general goal of increasing productivity and comfort of employees. The primary objective of this study is to objectively analyze the influence of the effect factor from end user's perspective and user satisfaction on SWP usage, intention for continuous usage and individual performance. To accomplish this research purpose, this study established research models and hypothesis by collective review about information system success models, and tested the research hypotheses using the structural equation modeling technique by data collected from 320 SWP system users of P corporation. Variations for system satisfaction evaluation standard are 1)SW system usage 2) intention for continuous usage 3) individual performance, effect variations are 1) social factors 2) technical factors 3) combination of social and technical factors. Therefore, this study is about influence factors on success of SWP system and how the factors impact the outcome. The test results of this research model is summarized as follows. Firstly, system user's satisfaction had positive impact on all three; SWP system usage, intention for continuous usage and individual performance. Secondly, social factor 'SWP control system' and technical factor 'information quality' and 'system quality' had positive impact on SWP system user satisfaction, while social factor 'shared value' and technical factor 'service quality' did not have significant effect on user satisfaction. Shared value however, had interactive effect with 'information quality' and 'service quality'. This study is expected to contribute to spread of academic research on smart work system by suggesting a model that can show important factors for corporation while explaining the successful implementation of SWP and its continuous usage.

• Journal of Power Electronics
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• 제18권6호
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• pp.1819-1829
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• 2018

A three-phase, three-switch, and three-level boost-type PWM rectifier (Vienna rectifier) is proposed as an active front-end power factor correction (PFC) rectifier for telecom loads. The proposed active front-end PFC rectifier system is modeled by the switching cycle average model. The relation between duty ratios and DC link capacitor voltages is derived in terms of the system input currents. Furthermore, the feasible switching states are identified and applied to the proposed system to reduce the switching stress and DC ripples. A detailed equivalent circuit analysis of the proposed front-end PFC rectifier is conducted, and its performance is verified through simulations in MATLAB. Simulation results are verified using an experimental setup of an active front-end PFC rectifier that was developed in the laboratory. Simulation and experimental results demonstrate the improved power quality parameters that are in accordance with the IEEE and IEC standards.

• 한국심리학회지 : 문화 및 사회문제
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• 제26권3호
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• pp.259-282
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• 2020

본 연구에서는 부모화를 다차원적으로 측정하고자 Jurkovic과 Thirkield(1999)가 개발한 가족돌봄의무 척도(Filial Responsibility Scale-Adult)의 과거시점을 국내 4년제 대학생 남녀 20대를 대상으로 타당화를 진행하였다. 먼저 원 척도를 한국어로 번안해서 총 30문항의 예비 척도를 구성하였고, 249명을 대상으로 문항분석 및 탐색적 요인분석을 실시하였다. 탐색적 요인분석에서는 일부 문항이 삭제되고, 원 척도의 3요인 중 한 요인인 정서적 부모화의 문항이 다른 요인에 포함되어, 새로운 2요인 15문항으로 나타났다. 이를 확인해 보기 위해 독립된 318명을 대상으로 확인적 요인분석을 실시했다. 원 척도에서 제시된 30문항 3요인 모형과 탐색적 요인분석의 결과로 얻은 15문항 2요인(정서적 경험, 돌봄 행동)모형을 경쟁 모형으로 하여 확인적 요인분석을 실시한 결과, 수정 2요인 모형의 적합도가 더 우수하여 수정 2요인 구조로 확정지었다. 이후 수렴타당도, 변별타당도, 예측타당도를 확인한 결과 양호한 것으로 밝혀졌다. 이러한 연구 결과를 바탕으로 시사점, 의의, 제한점, 후속 연구에 대한 제언을 논의하였다.

• Journal of Korean Neurosurgical Society
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• 제66권5호
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• pp.511-524
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• 2023

Objective : This animal model aimed to compare the rat group that received brain irradiation and did not receive additional treatment (only saline) and the rat group that underwent brain irradiation and received Granulocyte colony stimulating factor (G-CSF) treatment. In addition, the effects of G-CSF on brain functions were examined by magnetic resonance (MR) imaging and histopathologically. Methods : This study used 24 female Wistar albino rats. Drug administration (saline or G-CSF) was started at the beginning of the study and continued for 15 days after whole-brain radiotherapy (WBRT). WBRT was given on day 7 of the start of the study. At the end of 15 days, the behavioral tests, including the three-chamber sociability test, open field test, and passive avoidance learning test, were done. After the behavioral test, the animals performed the MR spectroscopy procedure. At the end of the study, cervical dislocation was applied to all animals. Results : G-CSF treatment positively affected the results of the three-chamber sociability test, open-space test and passive avoidance learning test, cornu Ammonis (CA) 1, CA3, and Purkinje neuron counts, and the brain levels of brain-derived neurotrophic factor and postsynaptic density protein-95. However, G-CSF treatment reduced the glial fibrillary acidic protein immunostaining index and brain levels of malondialdehyde, tumor necrosis factor-alpha, nuclear factor kappa-B, and lactate. In addition, on MR spectroscopy, G-CSF had a reversible effect on brain lactate levels. Conclusion : In this first designed brain irradiation animal model, which evaluated G-CSF effects, we observed that G-CSF had reparative, neuroprotective and anti-neurodegenerative effects and had increased neurotrophic factor expression, neuronal counts, and morphology changes. In addition, G-CSF had a proven lactate-lowering effect in MR spectroscopy and brain materials.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2008년도 추계 학술발표회
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• pp.893-903
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• 2008

A method for predicting surface failures which occur during heavy rainfall on mountain slopes is proposed by using the digital land form model that is obtained by reading altitude on a topographical map at 10m grid point space. A depth of a potential failure layer is assumed at each grid point. In the layer, an infiltrated water movement from cell to cell is modeled in the study (cell is a square of the grid). Infiltrated ground water levels which show the three dimensional effects of a topographical factor in an area can be hourly calculated at every cell by the model. The safety factor of every cell is also calculated every hour by the infinite slope stability analysis method with the obtained infiltrated ground water level. Failure potential delineation is defined here as the time when the safety factor becomes less than unity under the assumptions that effective rainfall is 20mm/h and continues 20 hours.

• Journal of Information Processing Systems
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• 제16권4호
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• pp.784-794
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• 2020

In order to effectively evaluate the urban water security, the study investigates a novel system to assess factors that impact urban water security and builds an urban water poverty evaluation index system. Based on the contribution rates of Resource, Access, Capacity, Use, and Environment, the study adopts the Water Poverty Index (WPI) model to evaluate the water poverty levels of 14 cities in Gansu during 2011-2018 and uses the least variance method to evaluate water poverty space drive types. The case study results show that the water poverty space drive types of 14 cites fall into four categories. The first category is the dual factor dominant type driven by environment and resources, which includes Lanzhou, Qingyang, Jiuquan, and Jiayuguan. The second category is the three-factor dominant type driven by Access, Use, and Capability, which includes Longnan, Linxia, and Gannan. The third category is the four-factor dominant type driven by Resource, Access, Capability, and Environment, which includes Jinchang, Pingliang, Wuwei, Baiyin, and Zhangye. The fourth category is the five-factor dominant type, which includes Tianshui and Dingxi. The driven types impacting the urban water security factors reflected by the WPI and its model are clear and accurate. The divisions of the urban water security level supply a reliable theoretical and numerical basis for an urban water security early warning mechanism.

• Geomechanics and Engineering
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• 제37권2호
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• pp.179-187
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• 2024

In this paper, a unified time-dependent constitutive model of Darcy flow and non-Darcy flow is proposed. The influencing factors of flow velocity are discussed, which demonstrates that permeability coefficient is the most significant factor. Based on this, the dynamic evolution characteristics of water inrush during tunneling through fault fracture zone is analyzed under the constant permeability coefficient condition (CPCC). It indicates that the curves of flow velocity and hydrostatic pressure can be divided into typical three stages: approximate high-velocity zone inside the fault fracture zone, velocity-rising zone near the tunnel excavation face and attenuation-low velocity zone in the tunnel. Furthermore, given the variation of permeability coefficient of the fault fracture zone with depth and time, the dynamic evolution of water flow in the fault fracture zone under the variable permeability coefficient condition (VPCC) is also studied. The results show that the time-related factor (α) affects the dynamic evolution distribution of flow velocity with time, the depth-related factor (A) is the key factor to the dynamic evolution of hydrostatic pressure.