• Transactions of the Korean Society of Mechanical Engineers B
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• v.34 no.1
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• pp.53-59
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• 2010

In this paper, we propose a novel chaotic micromixer of which mixing mechanism is based upon magnetohydrodynamic (MHD) multi-vortical flow generation in a simple straight microchannel. In the microchannel of the micromixer has electrodes patterned on two side walls and bottom wall. Lorentz forces are variously induced by changing applied voltages at the patterned electrodes in order to pump and mix conductive fluids in the microchannel. Three-dimensional computational fluid dynamics simulations were conduced to characterize mixing behaviors inside the MHD micromixer. The mixing efficiencies were also evaluated for the various flow conditions.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.46 no.1
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• pp.70-81
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• 2010

A mathematical model is formulated to study the effect of wall mass on the thermal performance of four different houses of different construction. This analytical study was motivated by the experimental work of Burch et al. An analytical solution of one -dimensional, linear, partial differential equation for wall temperature profiles and room air temperatures is obtained using the Laplace transform method. Typical Meteorological Year data are processed to yield hourly average monthly values. These discrete data are then converted to a continuous, time dependent form using a Fast Fourier Transform method. This study is conducted using weather data from four different locations in the United States: Albuquerque, New mexico; Miami, Florida; Santa Maria, California; and Washington D.C. for both winter and summer conditions. A computer code is developed to calculate the wall temperature profile, room air temperature, and energy consumption loads. Three sets of results are calculated one for no auxiliary energy and two for different control mechanism -- an on-off controller and a proportional controller. Comparisons are made for the cases of two controllers. Heavy weight houses with insulation in mild weather areas (such as August in Santa Maria, California) show a high comfort level. Houses using proportional control experience a higher comfort level in comparison to houses using on-off control. The result shows that there is an effect of mass on the thermal performance of a heavily constructed house in mild weather conditions.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.21 no.1
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• pp.125-131
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• 1997

The extinction of premixed flames under the influence of stretch is studied numerically. A wide range of fuel (hydrogen, ethylene, acetylene, methane, propane and methanol) and air mixtures are established in an opposed jet and their flame properties such as flame speed, flame thickness, thermal diffusivity, and stretch rate at extinction are computed. Computations are made using several chemical kinetic mechanism (Smooke, Kee et al. and Peters). The major result is that, in contrast to the various previous claims of extinction Karlovitz number varying over three orders of magnitude, it is found to be constant around two for all of the mixtures tested. That is, premixed flames are extinguished when the physical flow time decreases (due to increased stretch rate) to the point where it approximately equals the chemical reaction time. Here the relevant chemical reaction time is not the one computed using the one-dimensional flame properties as originally suggested in the formulation of Karlovitz number, but rather it is the one obtained using the stretched flame properties which fully reflect the effect of straining on the flame structure.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2004.10a
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• pp.1365-1368
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• 2004

A scheme to control the laser power and the exposure time was studied to fabricate precise microstructures using the nanostereolithography (nSL) process. Some recent works have shown that a three-dimensional (3D) microstructure can be fabricated by the photopolymerizing process which is induced by two-photon absorption (TPA) with a femtosecond pulse laser. TPA provides the ability to confine photochemical and physical reactions within the order of laser wavelength, so neardiffraction limit features can be produced. In the nSL process, voxels are continuously generated to form a layer and then another layer is stacked in the normal direction of a plane to construct a 3D structure. Thus, fabrication of a voxel with low aspect ratio and small diameter is one of the most important parameters for fabricating precise 3D microstructures. In this work, the mechanism of a voxel formation is studied and a scheme on the control of laser power and exposure for minimizing aspect ratio of a voxel is proposed.

• Journal of the Korean Magnetic Resonance Society
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• v.15 no.1
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• pp.25-39
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• 2011

Syndecan-4 is a transmembrane heparan sulfate proteoglycan, which is a coreceptor with integrins in cell adhesion. To get better understand the mechanism and function of Syndecan-4, it is critical to elucidate the three-dimensional structure of a single transmembrane spanning region of them. Unfortunately, it is hard to prepare the peptide because syndecan-4 is membrane-bound protein that transverse the lipid bilayer of the cell membrane. Generally, the preparation of transmembrane peptide sample is seriously difficult and time-consuming. In fact, high yield production of transmembrane peptides has been limited by experimental adversities of insufficient yields and low solubility of peptide. Here, we demonstrate experimental processes and results to optimize expression, purification, and NMR measurement condition of Syndecan-4 transmembrane peptide.

• Clinical and Experimental Pediatrics
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• v.49 no.12
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• pp.1363-1366
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• 2006

Aneurysmal dilatation of the ductus arteriosis has been considered a rare but potentially fatal abnormality. The mechanism of ductal aneurysmal formation remains uncertain. Plain chest radiography has proven helpful in the diagnosis of ductus arteriosus aneurysm (DAA), before the application of transthoracic echocardiography. The transthoracic echocardiography is an important tool for the diagnosis and follow-up of DAA. We present a case of congenital ductus arteriosus aneurysm in a newborn, that was an incidental discovery. The diagnosis was made by echocardiography, three-dimensional surface rendering computed tomography (CT), and spontaneous regression after four weeks of follow-up.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2003.10a
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• pp.5-5
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• 2003

The purple acid phosphatases comprise a family of binuclear metal-containing enzymes. The metal centre contains one ferric ion and one divalent metal ion. Spectroscopic studies of the monomeric, ${\sim}$36 kDa mammalian purple acid phosphatases reveal the presence of an Fe(III)Fe(II) centre in which the metals are weakly antiferromagnetically coupled, whereas the dimeric, ${\sim}$110 000 kDa plant enzymes contain either Fe(III)Zn(II) or Fe(III)Mn(II). The three dimensional structures of the red kidney bean and pig enzymes show very similar arrangements of the metal ligands but some significant differences beyond the immediate vicinity of the metals. In addition to the catalytic domain, the plant enzyme contains a second domain of unknown function. A search of sequence databases was undertaken using a sequence pattern which includes the conserved metal-binding residues in the plant and animal enzymes. The search revealed the presence in plants of a 'mammalian-type' low molecular weight purple acid phosphatase, a high molecular weight form in some fungi, and a homologue in some bacteria. The catalytic mechanism of the enzyme has been investigated with a view to understanding the marked difference in specificity between the Fe-Mn sweet potato enzyme, which exhibits highly efficient catalysis towards both activated and unactivated phosphate esters, and other PAPs, which hydrolyse only activated esters. Comparison of the active site structures of the enzymes reveal some interesting differences between them which may account for the difference. The implications fur understanding the physiological functions of the enzymes will be discussed.

• Journal of computational fluids engineering
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• v.16 no.4
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• pp.92-99
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• 2011

In order to protect the turbine blade from working fluid of high temperature, many cooling techniques such as internal convection cooling, film cooling, impinging jet cooling and thermal barrier coating have been developed. With all other things, film-cooling has been widely used as the important alternative. In the present work, numerical analysis has been performed to investigate and to compare the film-cooling performance of various film-cooling hole schemes such as cylindrical, crescent, louver, and dumbbell holes. To analyze the turbulent flow and the film-cooling mechanism, three-dimensional Reynolds-averaged Navier-Stokes analysis has been performed with shear stress transport turbulence model. The validation of numerical results has been assessed in comparison with experimental data. The characteristics of fluid flow and the film-cooling performance for each shaped hole have been investigated and evaluated in terms of centerline, laterally averaged and spatially averaged film-cooling effectivenesses. Among the film cooling holes, the dumbbell shaped hole shows better film-cooling effectiveness than the other shaped holes. And the louver and cylindrical shaped hole show the worst film cooling performance, and concentrated flows on near the centerline only.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.5 no.4
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• pp.271-278
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• 1993

Sand ripple. the smallest bottom configuration, is one of the most important factors in the mechanism of sand transport. This paper deals with characteristics of ripple geometry generated by regular and irregular waves. Especially. rearrangement of ripple spacing caused by increasing or decreasing waves is investigated through movable bed experiments. Nondimensional length of rearranged ripples becomes very close to that of measured ripples in the field Furthermore, stochastic characteristics and occurrence limits of three dimensional ripples are investigated through the wave number spectrum calculated from the measured bottom topography.

• Environmental Engineering Research
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• v.11 no.5
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• pp.241-249
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• 2006

A mathematical model is described for the prediction of convective upward transport of an organic solvent driven by evaporation at the surface, which is known as the major transport mechanism in the in-situ photolysis of a soil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin(TCDD). A finite-element model was proposed to incorporate the effects of multiphase flow on the distribution of each fluid, gravity as a driving force, and the use of hysteretic models for more accurate description of k-S-p relations. Extensive numerical calculations were performed to study fluid flow through three types of soils under different water table conditions. Predictions of relative permeability-saturation-pressure (k-S-p) relations and fluids distribution for an illustrative soil indicate that hysteresis effects may be quite substantial. This result emphasizes the need to use hysteretic models in performing flow simulations including reversals of flow paths. Results of additional calculations accounting for hysteresis on the one-dimensional unsaturated soil columns show that gravity affects significantly on the flow of each fluid during gravity drainage, solvent injection, and evaporation, especially for highly permeable soils. The rate and duration of solvent injection also have a profound influence on the fluid saturation profile and the amount of evaporated solvent. Key factors influencing water drainage and solvent evaporation in soils also include hydraulic conductivity and water table configuration.