• 제목/요약/키워드: Thermal therapy

검색결과 209건 처리시간 0.024초

온침이 만성요통에 미치는 효과에 대한 무작위배정 대조군 예비 임상연구 프로토콜 (Clinical Research of Warm Needle Acupuncture for Chronic Low Back Pain: A Protocol for Randomized, Controlled Pilot Study)

  • 서연호;김태오;조휘성;고준혁;안종현;김수전;이한솔;장호경;김형석;김고운;조재흥;정원석;송미연
    • 한방재활의학과학회지
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    • 제30권4호
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    • pp.155-164
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    • 2020
  • Objectives This study is aimed to evaluate the feasibility of further clinical research of warm needle acupuncture as an effective and safe treatment for chronic low back pain. Methods Thirty participants will be randomly assigned to the Warm needle acupuncture group (n=15) and Dry needle acupuncture group (n=15). All patients will receive acupuncture therapy twice a week for 6 weeks, but only the experimental group will receive thermal stimulation. The primary outcome will be measured using the visual analogue scale for bothersomeness of low back pain, and the secondary outcome will be measured using the VAS for pain intensity, Oswestry disability index, 36-Item Short Form Health Survey, Beck's depression inventory, and amount of analgesics used. Conclusions The results of this study will be used to determine the feasibility of a future large-scale randomized controlled trial that provides clinical evidence for the efficacy and safety of warm needle acupuncture in the treatment of patients with chronic low back pain.

만성 요통 환자의 자가 관리 요법에 따른 통증 및 기능의 변화 (Self-management techniques and subsequent changes in pain and function in patients with chronic low back pain)

  • 최준현;김은실;윤용순;김가은;이미현;장홍영
    • 디지털융복합연구
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    • 제18권10호
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    • pp.547-555
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    • 2020
  • 재활치료를 받고 호전된 만성 요통 환자들이 집에서 수행하는 자가 관리 프로그램의 효과를 알아보고자 63명을 자가 운동 (SEG), 핫팩 및 저주파 전기 자극 (HEG) 및 온열 마사지 (TMG) 3개 그룹으로 나누었다. 통증장애 지표로 통증 수치 등급 척도 (PNRS), Oswestry 장애 지수 (ODI) 및 Roland Morris 장애 설문지 (RMDQ)를 병원 내원시, 치료 후 및 가정에서 자가 관리 6 개월 후에 평가하였고 재발 빈도 (RF)를 내원 전 6 개월 전과 자가관리 6 개월 후에 평가하였다. 각 그룹 내의 비교에서 SEG 및 TMG의 PNRS, ODI, RMDQ는 6개월 후에도 효과가 유지되었으나, HEG에서는 치료 후 개선되었던 PNRS가 6개월 후에 악화되었다. 그룹간 비교에서 SEG 및 TMG의 PNRS, ODI, RMDQ 및 RF는 6개월 후에 HEG에 비해 더 좋았다. 운동과 온열 마사지는 요통 자가 관리 방법으로 고려볼 수 있으나, 향후 더 많은 환자들과 다양한 연령, 직업들을 고려하여 추가 연구가 필요하다.

Nd:YAG 레이저 조사시 치근면에 미치는 효과에 관한 주사전자현미경적 연구 (The Effects of Nd:YAG Laser Irradiation on the Root Surface;A Scanning Electron Microscopic Study)

  • 이수정;김수아;서석란;김형섭
    • Journal of Periodontal and Implant Science
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    • 제27권3호
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    • pp.495-514
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    • 1997
  • The purpose of this study was to evaluate the in vitro effects of Nd:YAG laser irradiation on removal of a root surface smear layer after root planing in comparison with Tetracycline HCl. The 60 extracted human teeth due to severe periodontal disease were vigorously scaled and root planed with Gracey curet. Thirty specimen($5{\times}5{\times}2mm$) were obtained from root planed surface of 30 human teeth and assigned randomly to one of three groups : root planed group(5 specimen), Tetracycline HCI group(5 specimen, burnished for 5 minutes), and Nd:YAG laser group(25 specimen, German Dental Laser, Fotona Twinlight). Nd:YAG laser group was divided into 4 subgroups according to power of 1W, 1.5W, 2W, 3W at frequency to 10Hz. The specimen were then fixed, and examed by Scanning electron microscopic study. 30 of 60 human teeth used to measurement of the intrapulpal temperature rise during laser irradiation. Laser-irradiated surface exhibited various surface texture from relative flat surface to irregular surface with patent dentinal tubules of various shape and size. In some area, the root surface alteration which are carbonization, pit and crater formation and melting and resolidification were observed. The number of exposed dentinal tubules per unit($100_{\mu}m^2$) on tetracycline HCI group was more than that in the laser group below 1.5W of power(150mJ/pulse) and was significantly less than that in laser group above 2W of power(200mJ/pulse)(P<0.OOl). As power increased the intrapulpal temperature rise also increased. The result suggested that the parameter which effectively remove root surface smear layer than tetracycline HCI may cause thermal damage to pulp and root surface alteration result from laser exposure would indicate need for additional instrumentation. Thus, Nd:YAG laser irradiation in these parameter may not be appropriate for clinical use as adjunct to conventional periodontal therapy.

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종양치료용 고주파 열치료 인체적용 시뮬레이션 (Simulation of the High Frequency Hyperthermia for Tumor Treatment)

  • 이강연;정병균;김지원;박정숙;정병호
    • 한국융합학회논문지
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    • 제9권3호
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    • pp.257-263
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    • 2018
  • 고주파 열치료법은 1MHz 이상의 RF 고주파 전류를 전극을 통해 종양조직으로 공급, 가열하여 종양조직의 온도를 $42.0^{\circ}C$이상으로 상승시켜 열괴사시키는 치료법으로 알려져 있다. 인체 내에서 전자기에너지의 흡수와 전달을 위한 수학적으로 모델링과 생물학적인 신체조직의 온도 필드 분포의 해석과 평가를 통해 생체조직을 구성하는 분자들이 진동하면서 서로 마찰되어 열에너지로 전환되는 과정을 분석할 수 있다. 본 논문에서는 3차원 모델의 기하학적 형상의 성인남자 표준모델을 토대로 인체모형을 설정하고, 계산은 유한체적법 코드를 활용하였다. 인체에 전극을 장착하여 외부에서 유도되는 자기장을 모사한 쥴열이 공급되는 것으로 가정하였고 이에 대한 온도분포를 0-1,200초 동안 해석하였다. 시뮬레이션의 결과, 전달된 에너지는 전극의 가장자리로부터 전극의 안쪽으로, 피부 표면으로부터 피하층으로 점진적으로 침투되어 폐종양세포에 전달되어 종양이 열괴사하는 과정을 확인할 수 있었다.

전립선비대증의 진료지침 개발을 위한 한국문헌의 메타분석 (Meta-analysis of the Korean Literatures for Developing Clinical Practice Guidelines of Benign Prostatic Hyperplasia)

  • 유승흠;김춘배;강명근;송재만
    • Journal of Preventive Medicine and Public Health
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    • 제30권3호
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    • pp.643-664
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    • 1997
  • This study is to provide evidence-based recommendations for the most-effective treatments of benign prostatic hyperplasia based on patient preference or clinical need, and to meta-analyze the Korean literatures for the development of BPH treatment guidelines. For these analyses, extensive literature searches (208 articles), with priority given to the Korean Journal of Urology, were conducted from 1960 to August, 1996. Meta-analysis, like all statistical analysis, has two main functions: data summarization (qualitative meta-analysis) and smoothing o. pattern recognition (quantitative meta-analysis). As well, critical reviews and syntheses with the mean and 90-percent confidence intervals for the likelihood were used to evaluate empirical evidence and significant outcomes of the BPH treatment literatures (106 articles). For this task, the Methodologic Panel for BPH Guidelines was composed of multidisciplinary experts in the field. The results of the study were summarized as follows: For all that watchful waiting is an appropriate treatment strategy for the majority of patients with prostatism, we couldn't find the Korean literatures which carried this article. The literatures on alpha-1-adrenergic receptor blockers provide no evidence to suggest that any one alpha blocker is more effective than another. The finasteride reduces the size of the prostate, on average, and leads to a small yet perceptible reduction in sysptoms. Of all treatment options, prostate surgery with transurethral resection of the prostate (TURP), transurethral incision of the prostate (TUIP), and so on, offers the best chance for symptom improvement. However, surgery also has the highest rates of significant complications. Therefore, surgery need not always be a treatment of last resort. Balloon dilation of the prostatic urethra is clearly less effective than surgery in relieving symptoms, but it is associated with fewer complications. Emerging technologies for treating BPH include lasers, coils, stents, thermal therapy and hyperthermia. Established technologies will also be reanalyzed as results of new trials are reported. Although this study has some limitations due to lacking for good quality literatures, ' it provides a cornerstone for our medical research. It represents the most current scientific knowledge regarding the clinical epidemiology including treatment of BPH. It will be revised and updated as needed.

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CTV 바이러스 보균 감귤나무로부터 열처리와 경정접목을 통한 바이러스 제거 (Micrografting and Heat Treatment Combination for Eliminating Virus of CTV-infected Citrus)

  • 채치원;윤수현;박재호;현재욱;고상욱;이동훈
    • 생명과학회지
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    • 제23권2호
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    • pp.267-272
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    • 2013
  • 본 연구는 바이러스에 감염된 감귤나무로부터 열처리와 경정접목을 병행 처리하여 바이러스를 제거코자 수행하였다. '세토카' 교잡종을 포함한 6품종을 재료로서 사용하였으며 이를 조사된 모든 개체에서는 외관적으로 바이러스 감염 증상이 관찰되지 않았으나 TAS-ELISA 검정을 통해 전원 CTV에 감염되어 있음이 확인되었다. '세토카'를 대상으로 특정 온도 시험을 수행한 결과, 주 야간 $40^{\circ}C$ 온도 조건에서 높은 비율로 바이러스가 제거되었다. 항혈청법으로 할 수 있었으며, 그 처리에서 획득된 무균의 신초를 이용하여 기내 파종된 탱자 대목에 경정 접목하였다. 경정 접목된 모든 개체에서는 바이러스 병징이 발견되지 않았고 TAS-ELISA와 SDV 크로마토법에 의해서도 무균이 확인되었다. CTV, SDV와 CTLV를 대상으로 한 RT-PCR 검사를 통해서도 극소량의 바이러스조차 발견되지 않았다. 따라서, 열처리와 경정접목을 통해 '세토카', '삼다조생', '풍광', '부지화' 및 '에히메카시 다이28고' 품종에서 총 11개의 무균의 식물체를 획득하였다.

Non-ablative Fractional Thulium Laser Irradiation Suppresses Early Tumor Growth

  • Yoo, Su Woong;Park, Hee-Jin;Oh, Gyungseok;Hwang, Soonjoo;Yun, Misun;Wang, Taejun;Seo, Young-Seok;Min, Jung-Joon;Kim, Ki Hean;Kim, Eung-Sam;Kim, Young L.;Chung, Euiheon
    • Current Optics and Photonics
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    • 제1권1호
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    • pp.51-59
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    • 2017
  • In addition to its typical use for skin rejuvenation, fractional laser irradiation of early cancerous lesions may reduce the risk of tumor development as a byproduct of wound healing in the stroma after the controlled injury. While fractional ablative lasers are commonly used for cosmetic/aesthetic purposes (e.g., photorejuvenation, hair removal, and scar reduction), we propose a novel use of such laser treatments as a stromal treatment to delay tumorigenesis and suppress carcinogenesis. In this study, we found that non-ablative fractional laser (NAFL) irradiation may have a possible suppressive effect on early tumor growth in syngeneic mouse tumor models. We included two syngeneic mouse tumor models in irradiation groups and control groups. In the irradiation group, a thulium fiber based NAFL at 1927 nm was used to irradiate the skin area including the tumor injection region with 70 mJ/spot, while no laser irradiation was applied to the control group. Numerical simulation with the same experimental condition showed that thermal damage was confined only to the irradiation spots, sparing the adjacent tissue area. The irradiation groups of both tumor models showed smaller tumor volumes than the control group at an early tumor growth stage. We also detected elevated inflammatory cytokine levels a day after the NAFL irradiation. NAFL treatment of the stromal tissue could potentially be an alternative anticancer therapeutic modality for early tumorigenesis in a minimally invasive manner.

合谷($LI_4$), 三間($LI_3$)의 電針刺戟이 顔面部 領域 溫度變化에 미치는 影響 (Effects on the Thermal Change of the Face Follow Electroacupunctyre on Hapkok($LI_4$), Sangan($LI_3$))

  • 윤정훈;김종한;황충연;임규상
    • 한방안이비인후피부과학회지
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    • 제12권2호
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    • pp.222-247
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    • 1999
  • The back ground and purpose : The acupuncture of oriental medicine is very important in treatments. Until now it has been researched according to the meridian and qi xue(氣血) phenomenon of oriental medicine's theory. As electroacupuncture is one of acupuncture treatments, it will show more objective index to observe the meridian and qi xue(氣血) phenomenon. And then, I studied the effects on the thermal change of the face following electroacupuncture treatment. Objective and Methods : This study was performed from January 1999 to March 1999 on 10 healthy students. The objective was divided into three groups, those were the control group A(n=10), the group B(n=10) of electroacupuncture on Hapkok($LI_4$), Samgan($LI_3$) and the group C(n=10) of electroacupuncture on Shinmun($H_7$), T' ongni($H_5$). First, in the control group A, we took a picture for 10 men without any stimulation with the Digital Infrared Thermograph Imaging(D.I.T.I.) and did 3min after, 10min after, 15min after, 25min after, 45min after respectively. Second, in the electroacupuncture treatment group B, we took a picture for 10 men without any stimulation, and then treat electroacupuncture on Hapkok($LI_4$), Samgan($LI_3$) and took a picture immediately(3min after), 10min after, 15min after and remove needle and took a picture in the same way respectively. Third, in the electroacupuncture treatment group C, we took a picture for 10 men without any stimulation, and then treat electroacupuncture on Shinmun($H_7$), T'ongni($H_5$) and took a picture in the second way respectively. Results: 1. In healthy men, average skin temperture about Yonghyang($LI_{20}$) area was higher than Soryo($G_{25}$) or Chich'ang($S_4$) area. They were Soryo($G_{25}$) area $31.495{\pm}0.766^{\circ}C$, Rt. Yonghyang($LI_{20}$) area $31.664{\pm}0.936^{\circ}C$, Lt. Yonghyang ($LI_{20}$)area $31.686{\pm}0.767^{\circ}C$, Rt. Chich'ang($S_4$) area $31.226{\pm}0.875^{\circ}$, Lt. Chich'ang ($S_4$) area $31.453{\pm}0.855^{\circ}C$. 2. In the control group A, the skin temperature of Soryo($G_{25}$) showed the increase or decrease in below ${\Delta}0.1^{\circ}C\;except\;0.265{\pm}0.594^{\circ}C$ in 25min, but not significantly. 3. About Soryo($G_{25}$) area, the skin temperature decreased significantly after electroacupuncture immediately. ${\Delta}T $of the group B was $-0.970{\pm}0.87\;1^{\circ}C$, which was larger than one of the group C which was $-0.707{\pm}0.624^{\circ}C$ at 3min. And then ${\Delta}T$ of the group C was increase valuable at 25min, 45min. 4. About Yonghyang($L1_{25}$) area, the left ${\Delta}T$ of the group B showed below $0.2^{\circ}C$ or so in contrast to the right it. In the group C, on the both side showed continous increase of temperature as following times. 5. About Chich'ang($S_4$) area, the skin temperature increased valuable $0.3^{\circ}C$ or so on the both side and later inclined to decrease in the group B but not significantly. In the group C, it increased valuable on the both side. 6. The skin temperature of electroacupuncture treatment group B, C were more increase than the control group A except Lt. Yonghyang($LI_{20}$) area in the group B. The temperature of group C were more increase than the group B wholly. Conclusion : The above results indicate that D.I.T.I. is a useful method to observe and fallow-up the effects and the changes by electroacupuncture stimulation on objective evaluation of phenomenon for the meridian system and character. Thus, continuous thermographic study will be needed for more clinical application such as acupuncture and medicine or laser therapy according to oriental medicine.

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진행된 장관골 골육종의 수술 및 비수술적 강력 집속 초음파 치료의 장기 추적 결과 (Clinical Outcome of Treatment for Stage IIA, IIB and III Osteosarcomas (Comparative Studies between Invasive Surgical Treatment and Non-invasive HIFU Technique))

  • ;;;;;;;;;;이승구;강용구;박원종;정양국;허성우;이은상
    • 대한골관절종양학회지
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    • 제12권1호
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    • pp.37-46
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    • 2006
  • 목적: 장관골의 골육종 치료로써 한국에서 시행된 항암제 치료 및 수술적 치료 후의 결과와, 중국에서 시행된 비침습적인 초음파 치료(high intensity focused ultrasound, HIFU)간의 다국적 임상 결과를 비교하고자 한다. 대상 및 방법: 한국에서 1993년 이래로 통상적인 항암요법과 사지구제술을 시행한 총 67예(IIA; 4 cases, IIB; 58 cases, III; 5 cases)와, 중국에서 1997년 이래로 초음파 치료를 시행한 총 71예(II; 57 cases, III; 14 cases)를 연구 대상으로 하였다. 한국에서는 총 67예 중, 66예에서 수술 전 선행 화학치료를, 반면 중국에서는 총 71예 중, stage II의 34예에서 9회 이상의 full protocol 화학치료가 시행되었고, stage II의 23예와 stage III의 14예에서 8회 이하의 부분 화학치료를 시행하였다. 한국의 67예는 모두 광범위 절제술을 시행하였고, 56예에서 국소 재건술을 병행하였다. 5예에선 국소 재건 없이 광범위 절제만 시행하였고, 6예에선 절단술만을 시행하였다. 반면 중국의 총 71예는 평균 1.5회(1~4회)의 초음파 치료가 시행되었다. 결과: 한국의 stage II의 5년 생존율은 평균 92.7%(IIA 100%, IIB 85.5%), 반면, 중국의 5년 생존율이 평균 78.7%로써 항암제를 병행한 군은 91.8% 및 항암제 치료를 못 받은 군은 56.6%였다. Stage III의 3년 생존율은 한국 20%(5예중 1예 생존), 중국은 7.1%(14예 중 1예 생존)였으며, 전 예의 평균 생존율은 한국 65.2%, 중국 51.8%였다(Table 2). 한국 환자들의 ISOLS에 의한 최종 기능 평가 결과는 평균 24.3(81%)였고, 중국 환자들은 19.8(73%)였으며, 치료의 합병증은 한국 25.4%(17/67 cases), 중국 31%였다. 결론: 한국에서 시행한 수술적 치료전후 화학요법을 시행한 결과는 초음파 치료를 이용한 비침습적 열괴사 방법보다 양호하였으나, 골종양에 대한 초음파 치료도 적응증을 잘 선택한다면 장관골 골육종의 치유 및 국소 재발율을 감소시킬 수 있을 것으로 생각한다.

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