• Journal of Periodontal and Implant Science
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• 제32권1호
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• pp.13-23
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• 2002

The ultimate goal of periodontal therapy is directed to arresting the progression of the disease, and regenerating the fibrous attachment. In order to achieve such treatment aim, the plaque and calculus must be eliminated and the physiological conditions of the root surface must be changed to facilitate the attachment and migration of the new fibroblasts, The method of changing the proper root surface conditions to promote the healing of periodontal tissue involves mechanical procedures, such as scaling and root planing, and chemical procedures such as tetracycline-HCl. However, the formation of a long junctional epithelium was most frequently observed type of healing. Thus, the aim of this study was to examine in vitro the influence of surface conditioning of dentin by TC-HCl on human gingival epithelial cell attachment. Human gingival epithelial cells were obtained from healthy retromolar pad area(under the age 23 years). Seventy two teeth extracted from severe periodontitis were used as study material. To evaluate the epithelial cell attachment to dentin, the prepared specimen was divided to four groups. For the control group, only scaling and root planing were carried out, and for the test group, 1 to 3, the concentration of the TC-HCl was 50, 125 and 250mg/ml respectively. After cell cultivation time of 1-, 3-. 24 hour, for the indirect quantitative assessment of gingival epithelial cell attached to dentin sample, the absorbance of epithelial cell unattached to dentin was measured. The results were as follows; 1. There was no statistically significant difference between scaling and root planing group and TC-HCl 50mg/ml 125mg/ml and 250mg/ml group about absorbance of unattached epithelial cell to dentin sample(p>0.5). 2. As time passes, the absorbance of unattached gingival epithelial cell to dentin sample was decreased statistically significant(p<0.05). 3. There was no statistically significant difference among the TC-HCl group(p>0.05) We concluded that there was similar effect on gingival epithelial cell attachment between TC-HCl conditioning on root surface and only scaling and root planing treatment

• Tuberculosis and Respiratory Diseases
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• 제46권3호
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• pp.386-393
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• 1999

연구배경 : 호흡곤란을 호소하는 폐질환 환자에 대하여 답차 및 자전거 운동을 시행하여 각각의 운동 부하 방법에 따른 심폐기능의 변화의 차이점을 알아 보고자 하였다. 방 법 : 호흡곤란을 동반한 남자 17명과 여자 4명을 대상으로 1주일 이상의 간격을 두고 무작위로 Sensor Medics사의 model No. 2900 자전거 작업계 (bicycle ergometer)와 Sensor Medics사의 Vmax29 treadmill을 이용하여 각각 incremental exercise를 실시하였다. 결 과 : 답차를 이용한 운동부하 폐기능 검사상 자전거 운동에 비하여 $VO_2max$, VEmax, 혐기성 역치값은 유의한 상승을 보였으며, 호흡 및 심박수 예비력은 유의한 감소를 보였다. 결 론 : 운동부하 검사 방법에 따라 호흡기 질환 환자에서 심폐기능 검사치의 유의한 차이를 보이므로 어떠한 운동 부하 방법을 사용하였는지에 따라 결과 해석에 고려가 필요할 것으로 사료된다.

• Tuberculosis and Respiratory Diseases
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• 제56권4호
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• pp.420-425
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• 2004

관상동맥-폐동맥 누공은 비교적 드문 질환으로 선천적 원인이 대부분이나 최근 흉부 시술이나 방사선 치료의 증가로 점차 후천적 원인이 많아지는 추세이다. 증상이 비특이적이어서 진단이 늦어질 수 있어 주의를 요한다. 저자들이 경험한 환자는 기존의 폐질환 증상 때문에 심장 혈관 질환의 진행을 예측하기 어려웠다. 약간의 논쟁이 있으나 원인에 계 없이 크기가 작은 누공에서는 추적관찰이, 중등도 이상의 크기이거나 확장 가능성이 있는 경우에는 누공을 막거나 원인혈관을 제거하는 방법이 장되고 있다. 예후는 대체로 양호한 편이다.

• 보건교육건강증진학회지
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• 제15권1호
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• pp.115-131
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• 1998

Understanding average abnormal obese high school students' health awareness and attitude, We analyzed problems affect on this to provide basic data for the school health education in the near future. From March, 1997, covering a month period, We investigated 300 average obese students from each 3 school, both boys and girls, around Taegu area. Followings are the summary. 1) Grouping obesity, 86.6% of boys were abdominal type and 54.0% of girls were lump types. 2) IN physical check-up and serum lipid lab., there were a lot of abnormal students for blood pressure, serum glucose, total cholesterol, high density lipoprotein(HDL), low density lipoprotein(LDL), neutral lipid, the rate of lipid in the body, atherosclerosis index and electrocardiogram (ECG).; Especially, for the rate of Lipid in the body, 100.0% were in the abnormal range. 3) The main reasons of stress were on the physique and grade. Over 50.0% of students get rid of their stress by singing and dancing. 4) 46.7% of boys and 56.0% of girls were satisfied with their desks and 51.3% of boys and 48.0% of girls were satisfied with their chairs.; 70.0% of boys and 78.7% of girls usually felt uncomfortable for their desks and chairs. 5) 100.0% of boys and 98.0% of girls have been educated for obesity.; 53.3% of boys and 50.7% of girls were not interested in whether joining in or not, if ‘Obese school’ is open. 60.7% of boys get information about weight loss from television, while 41.3% of girls get it from all sorts of publications.; Both sexes said eating convenience food is the main reason to be obese. Most frequent disease is high blood pressure.; 30.0% of boys and 31.3% of girls were hypertensives. 6) 84.7% of boys and 78.0% of girls are awake to the seriousness of obesity from their families. 58.7% of boys and 66.0% of girls sometimes have meals with their families. For the boys, 30.0% of them eat fruit and 29.3% eat cookies while 37.3% of girls eat cookies for their snacks. Both 57.3% of boys and 40.0% of girls have a snack once a day and they drink soft drinks frequently. Both 32.0% of boys and 46.7% of girls have midnight meals 1-2times a week. 7) Both 45.3% of boys and 50.0% of girls suddenly gained their weight in the elementary school times. 30.0% of boys exercise 1 hour for a week, while 48.0% of girls don't exercise. For the exercise hour, both 53.3% of boys and 42.0% of girls exercise for 10-30 minutes a time. 59.7% of boys and 82.0% of girls strongly don't trust in the informations on weight loss. Both 74.0% of boys and 75.3% of girls think physical therapy is the most suitable way for obesity care.

• 대한의료기공학회지
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• 제18권1호
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• pp.146-165
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• 2018

Objective : The purpose of this review is to overview and evaluate the trends of the studies in J. of The Korean Academy of Medical Gi-Gong. Methods : All 186 articles' headlines and abstracts from voI.1(1996) to Vol.17(20l7) were evaluated and classified. The dataset was searched from the Hompage of the Korean Academy of Medical Gi-Gong. Results : 1. In the type of study, the literature studies consisted of 67%(126studies), clinical studies 21%(39), experimental studies 12%(22) in order. 2. Gigong classification was 60.96%(114studies) while Non-Gigong classification was 37.04%(73studies). 3. In Gigong classification, General Gigong took the largest part and there were no Taoist Sexual Practices studies. 4. In Non-Gigong classification, Obstetrics & Gynecology & Pediatrics took the largest part by 25 studies(12.37%). An-Kyo-Hak was the second largest by 24 studies(11.88%). 5. Analysis Research(112 studies, 59.89%) took the largest part in study method. Conclusions : 1. The Korean Academy of Medical Gi-Gong published average 8.9 studies per year(187 studies per 21 years). 2. Following the object of The Korean Academy of Medical Gi-Gong, 114 studies(60.96%) of total 187 studies, published by J. of The Korean Academy of Medical Gi-Gong, were associated to Gigong. 3. In Non-Gigong classification, 25 studies about Obstetrics & Gynecology & Pediatrics, 24 studies about An-Kyo-Hak, 16 studies about Acupuncture & Moxibustion Medicine and Meridian & Acupoint Study were published by J. of The Korean Academy of Medical Gi-Gong. 4. In Gigong classification, studies about Meditation and External Gigong Therapy were insufficient. There are even no studies about Taoist Sexual Practices. We need more studies about those categories to come.

• 동서간호학연구지
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• 제8권1호
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• pp.41-49
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• 2003

Introduction: The purpose of this study was to compare the different concepts of oriental nursing as perceived by nurses, doctors, and patients in oriental hospitals. Method: A descriptive survey design was used for this study. Fifty-eight nurses, 26 doctors and 28 inpatients in 3 oriental hospitals were recruited from October to December 2002. The data were collected through a semi-structured open questionnaire. The data were analyzed by content analysis. Result: 1. The perceived concept of oriental nursing varied among the subjects. The nurses regard it as "a traditional nursing activity based on oriental philosophy" (60.3%), while the doctors viewed it as "a supplement to western nursing activity"(38.5%). For patients, the oriental nursing activity was considered as "a cordial form of nursing like that from a family member" (50.0%) and "an activity that doesn't differ so much from western nursing" (42.8%). 2. As for oriental nursing activities actually practiced, both the nurses and the doctors agreed that they carry out traditional oriental nursing activities such as explaining the treatment (taking oriental medicines, administering acupuncture etc.; nurses 96.6%, doctors 57.7%) and direct care like removing acupuncture needles (nurses 43.1%, doctors 34.6%). Patients replied that a western nursing activity is performed rather than an oriental nursing activity. 3. As for the required oriental nursing activity, nurses stated they apply traditional oriental methods such as CHUNA exercise therapy, moxibustion, cupping method etc. in their nursing practice. Doctors remarked that they try to understand the patients' state by approaching patients through an oriental way of thinking. Patients wish to get kindly care. 4. As a whole, 34.5% of nurses and 25.0% of patients have experienced little satisfaction from oriental nursing activity. Nurses found it valuable to carry out western nursing (39.3%), while patients found satisfaction in the use of a cordial attitude (39.9%). 5. Both nurses and doctors defined the first reason that oriental nursing activity cannot be performed more often was the lack of education in oriental nursing, and the absence of interest in oriental nursing. Conclusion: Nurses and doctors appreciate an oriental way of nursing, and think that this type of nursing activity has been carried out even though it may be infrequent. However this oriental nursing activity has won recognition from patients who view western nursing activity as being more important.

• 약학회지
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• 제58권2호
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• pp.141-149
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• 2014

Background: Oriental lifestyle for treating diseases has been developed and well-accepted for a long time among Koreans. Sasang Constitution theory, originated from Korean traditional medicine, suggests that medication treatment should be differentiated by each patient's body classification (So-yang [SY], So-eum [SE], Tae-yang [TY], and Tae-eum [TE]), in contrary to western medicine's theory that medication should be applied equally by disease indication without such classification. However, the pharmacotherapeutic outcomes of these theories have not been compared to date. In this study, we aimed to compare the two theories by evaluating blood pressure (BP), which is lowered as a therapeutic outcome, among hypertensive patients taking angiotensin II receptor blockers (ARBs) or calcium channel blockers (CCBs), two most commonly used antihypertensive classes in Korea. Methods: From April 2006 to June 2012, we retrospectively collected data on hypertensive patients with Sasang Constitution classification at Kyunghee University Hospital at Gangdong, one of the East-West collaborative medical centers in Korea. We collected information on age, gender, underlying diseases, antihypertensive drugs (ARB, CCB, ARB+CCB), and BP by reviewing the electronic medical records. We excluded patients with missing blood pressure at baseline or follow-up, or those who had a change in their antihypertensive drug class during follow-up. Results: We selected a total of 573 patients (SY: 165, SE: 158, TY: 0, TE: 250). Baseline BPs were on average 139.0/82.0 mmHg for SY, 137.8/78.5 mmHg for SE, and 138.7/79.2 mmHg for TE. In all three groups, CCBs were the most prescribed, followed by combination therapy with ARB+CCB, then ARBs. BP reduction after 1 month of initial medication was significantly different among the drug classes, but not in Sasang constitutional classification (ARB [SY: -12.4/-4.7, SE: -12.3/-2.5, TE: -8.6/-1.8], CCB [SY: -12.3/-5.4, SE: -13.0/-2.3, TE: -10.8/-6.0], ARB+CCB [SY: -15.6/-6.7, SE: -18.4/-8.1, TE: -20.2/-6.7], drug [$P{\leq}0.05$/P>0.05], constitutional type [P>0.05/P>0.05]). Conclusion: We observed significant differences in reduction of blood pressure by classes of drugs (ARB+CCB>CCB>ARB) but not by Sasang constitutional classification. Therefore, current approach of antihypertensive pharmacotherapy assisted by Western medicine is appropriate for treatment of hypertension. However, further larger scale or prospective studies are required in order to confirm these results.

• Journal of Acupuncture Research
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• 제25권5호
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• pp.105-116
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• 2008

Objectives : The objective of this study is to investigate the suppressing effect of the cervi pantotrichum cornu pharmacopuncture on the expression of iNOS mRNA and production of NO in synoviocytes from artificially arthritis-induced mice. Methods : In vitro test, synoviocytes extracted from a knee joint of a mouse were cultivated, and the herbal extract of cervi pantotrichum cornu($0.4mg/m{\ell}$, $0.6mg/m{\ell}$, $0.8mg/m{\ell}$, and $1.0mg/m{\ell}$) was added into the wells of synoviocytes to suppress the expression of iNOS mRNA and production of NO. In vivo test, each ten mice were allocated into three groups; Normal group, CIA-elicitated group(CIA), and group treated with cervi pantotrichum cornu pharmacopuncture after CIA elicitation(CCA). The extract of cervi pantotrichum cornu was injected into the acupoint of $SP_{10}$ to observe the changes of foot thickness in mice and the suppression of MIF, TNF-$\alpha$, NF-${\kappa}B$ p65, and iNOS. Results : In vitro test, the expression of iNOS mRNA and production of NO were dose-dependently decreased in the wells of synoviocytes treated with PMA. In vivo test, the suppression of MIF, TNF-$\alpha$, NF-${\kappa}B$ p65, and iNOS was clearly shown in the pieces of the synovial joint treated with the extract of cervi pantotrichum cornu. The foot thickness also decreased dose-dependently. Conclusions : It is speculated that the cervi pantotrichum cornu pharmacopuncture can be applicable to the therapy of rheumatoid arthritis by suppressing the expression of iNOS mRNA and production of NO.

• Tuberculosis and Respiratory Diseases
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• 제61권5호
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• pp.473-478
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• 2006

저자들은 폐암 및 항암치료에 의한 만성 질환으로 유발된 중등도의 빈혈이 있어 농축적혈구의 수혈치료 후 발생한 호흡곤란 및 발열 호소하여 다른 원인 감별 후 수혈에 의해 유발된 급성 폐 손상 진단하에 대증치료후 환자의 증상은 호전되었다. 이러한 수혈에 의해 유발된 급성 폐 손상은 그간 국내에서 보고 된 적이 없었던 증례로 이를 문헌 고찰과 함께 보고하는 바이다.

• Journal of Gastric Cancer
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• 제7권3호
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• pp.160-166
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• 2007

목적: 진행성위암의 경우 근치적 수술 후 보조항암요법에도 불구하고 5년 생존율이 그리 높지 않은 것으로 보고되고 있다. 이에 항암제 감수성 검사를 기초로 한 항암요법은 최소한 환자들에게 효과가 없는 약제 투여를 막을 수 있는 기회를 제공할 수 있다는 측면에서는 고무적이라 할 수 있다. 본 연구에서는 보조항암요법의 효과를 높이기 위한 유효약제 선정을 위하여 항암제 감수성검사를 실시하였으며 그 결과를 분석하여 항암제 선택에 이용하고자 임상병리학적 요인에 따른 항암제 감수성을 비교하였다. 대상 및 방법: 2005년 8월부터 2006년 8월까지 영남대학교 병원 외과에서 위절제술을 받은 위암환자 81명의 위암절제조직을 이용하여 항암제 감수성 검사를 실시하였다. 검사방법은 ATP (Adenosine Triphosphate) based chemotherapy response assay였다. 항암제 감수성과 임상병리학적 요인과의 상관관계를 보기 위하여 성별, 연령, 종양표지자(CEA 치, CA19-9 치), 암의 위치, 진행암 형태, 조직학적 형태, 분화 유무, 침윤도, Lauren 분류, Ming 분류, 림프관 침윤 유무, 맥관 침윤 유무, 신경 침윤 유무, 림프절 전이 유무, 병리학적 병기를 선정 비교하였다. 결과: 위암 환자를 대상으로 한 항암제 감수성 순위를 보면 5-FU, Epirubicin, Irinotecan, Oxaliplatin 순이었으며 통계학적으로 유의했다(P=0.000). 성별, 연령, 종양표지자(CEA 치, CA19-9치), 암의 위치, 진행암 형태, 조직학적 형태, 분화 유무, 침윤도, Lauren 분류, Ming 분류, 림프관 침윤 유무, 맥관 침윤 유무, 신경 침윤 유무, 림프절 전이 유무, 병리학적 병기 모두에서 유의하게 감수성의 차이를 보였다. 결론: 위암절제조직에서 시행한 항암제 감수성 순위는 5-FU, Epirubicin, Irinotecan, Oxaliplatin의 순이었으며 위절제술을 받은 위암환자의 절제조직을 이용 항암제 감수성검사를 시행한 결과 약제별 임상병리학적 인자에 따라 감수성의 차이가 있으므로 획일적인 항암화학요법을 실시하는 것보다 항암제 감수성 검사를 통하여 감수성 높은 약제들을 조합하여 사용하는 것이 바람직할 것으로 보인다.