• Title/Summary/Keyword: The safe factor

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Effects of Lifestyle and Dietary Behavior on Cardiovascular Risks in Middle-aged Korean Men

  • Yim, Kyeong-Sook
    • Journal of Community Nutrition
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    • v.2 no.2
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    • pp.119-128
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    • 2000
  • Lifestyle and dietary behavior intervention as the primary prevention of lipid disorder seems safe and compatible with other treatments of cardiovascular diseases. Cross-sectional associations between lifestyle factors and dietary behavioral factors with plasma lipid and lipoprotein levels were analyzed in 189 middle-aged men in Suwon, Korea. Overnight fasting plasma levels of total cholesterol, high-density lipoprotein(HDL)-cholesterol, triacylglycerol and glucose were analyzed. Blood pressure and anthropometric data were also measured. Lifestyle factors such as smoking status, alcohol consumption and frequency of physical exercise were evaluated by a self-administered questionnaire. Questions regarding dietary behavior were also asked. The subjects were 43.8%${\pm}$7.9 years old, and 23.8%${\pm}$2.6kg/m$^2$. From stepwise regression analyses, significant correlates with total cholesterol level were body mass index(BMI), alcohol intake(negative), age and coffee drinking(model R$^2$=14.3%). BMI, breakfast-skipping, age, and sleeping hours were significant for triacylglycerol level(model R$^2$=15.8%). BMI, alcohol drinking(negative), age, and coffee drinking were significant for low-density lipoprotein(LDL)(model R$^2$=11.7%). Age(negative), BMI(negative), alcohol drinking, stress level(negative), physical exercise, and cigarette smoking(negative) were significant for high-density lipoprotein(HDL)(model R$^2$=12.1%). From stepwise regression analyses, excluding BMI and age as factors in the model, alcohol intake(negative) and coffee drinking were significantly correlated with total cholesterol level(model R$^2$=4.4%) : breakfast-skipping with triacylglycerol(model R$^2$=3.2%) : alcohol intake (negative) with LDL level(model R$^2$=3.4%) : alcohol intake, physical exercise and stress level(negative) with HDL level(model R$^2$=6.3%). The findings suggest that a healthy daily lifestyle and dietary behavior may have an anti-atherogenic effect by altering plasma lipid and lipoprotein levels in middle-aged Korean men. (J Community Nutrition 2(2) : 119∼128, 2000)

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Toxicological Evaluation of Saposhnikoviae Radix Water Extract and its Antihyperuricemic Potential

  • Kim, Chang Won;Sung, Jae Hyuck;Kwon, Jeong Eun;Ryu, Hyeon Yeol;Song, Kyung Seuk;Lee, Jin Kyu;Lee, Sung Ryul;Kang, Se Chan
    • Toxicological Research
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    • v.35 no.4
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    • pp.371-387
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    • 2019
  • Although the dried root of Saposhnikovia divaricata (Turcz.) Schischk. (Umbelliferae) is a popular medicinal plant in East Asia, there has been no systemic toxicological evaluation of a water extract of Saposhnikoviae Radix (SRE). In this experiment, an oral acute and 13-week subchronic toxicological evaluations of SRE (500-5,000 mg/kg body weight) were performed in both sexes of Crl:CD(SD) rats. Based on the results from mortality, clinical signs, effects on body weight and organ weight, clinical biochemistry, hematology, urinalysis, and histopathology, significant acute, 4-week repeated dose range finding (DRF) and 13-week subchronic toxicity of SRE was not observed in either sex of rats; thus, the no observed adverse effect level (NOAEL) was 5,000 mg (kg/day). To identify anti-hyperuricemia potential of SRE, the suppressive effect of SRE was determined in mice challenged with potassium oxonate (PO; 250 mg/kg) via intraperitoneal injection for 8 days (each group; n = 7). SRE supplementation suppressed the uric acid level in urine through significant xanthine oxidase (XO) inhibitory activity. Kidney dysfunctions were observed in PO-challenged mice as evidenced by an increase in serum creatinine level. Whereas, SRE supplementation suppressed it in a dose-dependent manner. Collectively, SRE was safe up to 5,000 mg (kg/day) based on NOAEL found from acute and 13-week subchronic toxicological evaluations. SRE had anti-hyperuricemia effect and lowered the excessive level of uric acid, a potential factor for gout and kidney failure.

Priority Analysis for Consumers' Purchasing Factors of Seafood Online Using AHP Method (온라인 플랫폼을 활용한 수산식품 구매요인 우선순위 분석: AHP 기법을 활용하여)

  • Jeong, Hyun-Ki;Kee, Hae-Kyung;Park, Se-Hyun
    • Asia-Pacific Journal of Business
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    • v.13 no.3
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    • pp.449-461
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    • 2022
  • Purpose - The purpose of this study to explore factors consumers prioritize when purchasing seafood online. The originality of the study lies on adopting AHP-based approach in analyzing prioritized purchasing factors of seafood online. Design/methodology/approach - A survey was conducted targeting Korean consumers who have purchased seafood online. AHP method was applied to rank factors consumers prioritize before making decision. Findings - First, product's factor ranked first among other high level factors including delivery service, seller, online platform. Second, sanitation, taste, country of origin ranked first, second, third respectively, within product's factors. Third, safe delivery, timeliness, information accuracy ranked first, second, third respectively, within delivery factors. Fourth, consumer reviews, consumer response ability, promotion ranked first, second, third within seller factors. Fifth, Personal information management system, credibility, user-friendliness ranked first, second, third, within online platform factors. Research implications or Originality - To activate seafood online market, it is crucial to assure consumers that the seafood is well managed in a sanitary way from the production site to table. Existing government programs such as seafood traceability system, HACCP, and cold-chain infrastructure needs improvement. Due to highly perishable characteristic of seafood, delivery factors matter when purchasing online. Online platforms needs to continue to improve delivery service. Seafood products are mostly not branded and without objective information about their properties. Creating quality classification and seafood brands are likely to help consumers chose seafood online.

Discriminating Risky Drivers Using Driving Behavior Determinants (운전행동 결정요인을 이용한 위험운전자의 판별)

  • Ju Seok Oh ;Soon Chul Lee
    • Korean Journal of Culture and Social Issue
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    • v.18 no.3
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    • pp.415-433
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    • 2012
  • This study was conducted in order to explain the effect of driving behavior determinants such as drivers' personality and attitude that may induce risky driving behavior and to develop a valid method for discriminating risky drivers using the determinants. In the results of surveying 534 adult drivers, 5 driving behavior determinants (avoidance of problems, benefit/stimulus seeking, interpersonal anxiety, interpersonal anger, and aggression) were found to have a statistically significant effect on drivers' various risky driving behaviors. Using these factors, drivers were grouped according to risk levels (normal drivers, unintentionally risky drivers, and intentionally risky drivers). This result suggests that drivers' dangerous behavior level can be predicted using psychological factors such as their personality and attitude. Accordingly, if the driving behavior determinant model and the base score system used in this study are improved through further research, they are expected to be useful in predicting drivers' recklessness in advance, identifying problems, and providing differentiated safe driving education services based on the results.

The Study on the Physiological Activities of Beta vulgaris such as Antioxidant and Anti-inflammatory in RAW 264.7 cells (RAW 264.7 세포에서 레드비트의 항산화 및 항염증 등의 생리활성 연구)

  • Ji, Joong-Gu
    • Journal of the Korean Applied Science and Technology
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    • v.38 no.1
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    • pp.309-317
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    • 2021
  • This study was designed to examine the cell cytotoxic, anti-inflammatory, and antioxidant activity for raw material of Beta vulagaris tea. Antioxidative ability was evaluated by bioassays using DPPH and ABTS radical scavenging activity. Cell viability was assessed by MTT assay using RAW 264.7 cells, and investigated production levels of reactive oxide speies, and inflammatory meditors(i.e., nitric oxide, tumor necrosis factor-α, and interleukin-6) in LPS-induced RAW 264.7 cells. As a results, DPPH and ABTS raidcal scavenging activity were increased in a dose-dependent manner, and confirmed no cytotoxicity in all concentration. Also, it was significantly decreased level of ROS, NO, IL-6, and TNF-a in LPS-induced RAW 264.7 cells. Therefore these results suggest Beta vulagaris has considerable potential as a raw material of leached tea with safe anti-oxidative and anti-inflammatory effects.

Critical Factors Influencing on the Level of Service for Proactive Maintenance in Educational Facilities (교육 시설물의 선제적 노후화 관리를 위한 유지관리 서비스 수준의 인지요인 도출)

  • Shin, SeungWoo;Yi, JuneSeong;Son, JeongWook
    • Korean Journal of Construction Engineering and Management
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    • v.16 no.3
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    • pp.24-35
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    • 2015
  • Aging educational facility shall be managed and maintained through integrated service perspectives, in consideration of functions of each facility to provide safe and comfortable environment, rather than temporarily fixing/repairing problems. For doing this, it is a must to firstly understand the limitation of highly biased performance-based maintenance practice, which is a most common type applied at present, and therefore to establish maintenance system that reflects the functions and characteristics of maintenance service that a facility was designed with. Therefore, the objective of this study is to find items that have an influence on service level recognition in order to fairly evaluate service functions of educational facilities, and subsequently to use these factors as ingredients of establishing a consistent and efficient maintenance system. Therefore this study proposed explanatory variables to measure influential factors for each major maintenance category. Then appropriate statistical verification was carried out on questionnaires that collected from a number of industry experts to test its fe asibility.

Preference Survey of Smartphone Evacuation Guidance Map Components (스마트폰 피난안내도 구성요소 선호도 조사)

  • Bae, Young-Hoon;Jee, Ho-Joon;Jeon, Eun-Goo;Son, Jong-Yeong;Choi, Se-Hyu;Hong, Won-Hwa
    • Fire Science and Engineering
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    • v.33 no.5
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    • pp.78-85
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    • 2019
  • In complex buildings, Way-finding is the most important factor for safe evacuation. Recently, evacuation guidance systems using smartphones have been developed. However, smartphone evacuation guidance maps used in these studies appear different from those used in previous studies due to the lack of established standards. Therefore, in this study, we conducted a preference survey of evacuation guidance maps as a basic research for establishing evacuation guidance maps using smartphones. The components of smartphone evacuation guidance maps were selected using regulations and analyses conducted in previous studies, and preference surveys were conducted using the size of each component. Through this research, we suggested a method to create a high preference for each component of an evacuation guidance map.

A Technical Review of Hydromechanical Properties of Jointed Rock Mass accompanied by Fluid Injection (유체 주입을 동반한 절리 암반의 수리-역학 특성 평가에 대한 고찰)

  • Kim, Hyung-Mok;Guglielmi, Yves;Rutqvist, Jonny;Park, Eui-Seob
    • Tunnel and Underground Space
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    • v.29 no.1
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    • pp.12-29
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    • 2019
  • Permeability and its change due to a fluid injection in jointed rock mass is an important factor to be well identified for a safe and successful implementation of Carbon Capture and Sequestration (CCS), Enhanced Geothermal System (EGS) and Enhanced Oil Recovery (EOR) projects which may accompany injection-induced hydromechanical deformation of the rock mass. In this technical report, we first reviewed important issues in evaluating initial permeability using borehole hydraulic tests and numierical approaches for understanding coupled hydromechanical properties of rock mass. Recent SIMFIP testing device to measure these hydromechanical properties directly through in-situ borehole experiments was also reviewed. The technical significance and usefulness of the device for further applications was discussed as well.

Analysis of the effects of the work environment and layout of wheelhouse of coastal improved stow net fishing boats on the physical abnormalities of the workers (연안개량안강망어선 조타실의 작업환경 및 배치가 종사자의 신체 이상에 미치는 영향 분석)

  • KIM, Min-Son;CHANG, Ho-Young
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.57 no.2
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    • pp.162-172
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    • 2021
  • This study was conducted to determine whether the layout of wheelhouse and work environment of coastal improved stow net fishing boats affect the physical abnormalities of wheelhouse workers through a survey and to use it as basic data to improve the wheelhouse work environment. The analysis results are as follows. The result of factor analysis on the wheelhouse work environment was classified into three factors: suitability of work environment, suitability of work space arrangement, and layout of navigational and fishing equipment. The result of factor analysis on physical abnormalities was divided into two factors: physical pain and fatigue. The results of regression model analysis showing factors affecting physical pain showed that the t-value in the regression model was 3.625 (p < 0.05), indicating that the work environment suitability had an effect on the physical pain. Work environment suitability had a significantly positive effect on the physical pain. As work environment suitability increased by 1, the physical pain increased by 0.371 (p < 0.05). The results of regression model analysis showing the influencing factors on fatigue were found to have a t-value of 3.009 (p < 0.05) in the regression model, indicating that the work environment suitability had a significantly positive effect on the feeling of fatigue. It was found that fatigue increased by 0.324 (p < 0.05) as the work environment suitability increased by 1. In addition, the manageability of task suitability was found to be t = -2.521 (p > 0.05). As the manageability of task suitability increased, the skipper's fatigue level decreased. From these results, it is inferred that the wheelhouse of the current coastal improved stow net fishing boats causes physical pain and fatigue for the skippers. In order to reduce such physical pain and fatigue, and to improve safe fishing operation and job satisfaction, it is necessary to provide a wheelhouse to fishermen on coastal improved stow net fishing boats in consideration of the characteristics of the wheelhouse work of fishing boats and in consideration of users.

Development and Application of Traffic Accident Forecasting Model for Signalized Intersections (Four-Legged Signalized Intersections In Kwang-Ju) (신호교차로 교통사고 예측모형의 개발 및 적용 (광주광역시 4-지 신호교차로를 중심으로))

  • 하태준;강정규;박제진
    • Journal of Korean Society of Transportation
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    • v.19 no.6
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    • pp.207-218
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    • 2001
  • As a city and industries are developed rapidly, a traffic accident and congestion take places on the road link become serious and it can be a large problem of the society in the future. Especially, most of the traffic accidents on the signalized intersection are caused by the human factor, vehicle and environmental factor mutually. The relation of the traffic accident and volume is acting on the outbreak of the traffic accident and the mistake of driver altogether as a major cause. The purpose of this paper is to develop a model for the forecasting of the traffic accident and to use research data gained to predict many traffic accidents. The data of this study were used with real one of the 73 areas of the four-legged signalized intersection in Kwang-ju city from 1996 to 1998 for three years to develop a model for the forecasting of the traffic accident. The statistical methods used in this paper are the principal component, regression and correlation analysis. We studied accident models to find out useful data from the statistics method and applied the data to the different area of the Choun-La province for the verification of the model. So, the result of this paper showed a reasonable model for the forecasting or the traffic accident and possibility of the model for simulating on real case. Finally, This study would be made of a study continually for the safe design and plan for the four-legged signalized intersection.

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