• Journal of Radiation Industry
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• v.4 no.3
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• pp.203-207
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• 2010

Radiation-induced late injury to normal tissue is a primary area of radiation biology research. The present study was undertaken to investigate whether the late effect of the ionizing radiation appears as an age-related oxidative status in the brain. Three groups of 4-month old C57BL/6 mice that were exposed to $^{137}Cs$ ${\gamma}-rays$ at a single dose (5 Gy) or fractionated doses ($1Gy{\times}5times$, or $0.2Gy{\times}25times$) at 2 months old were investigated for the oxidative status of their brains with both young (2-month) and old (24-month) mice. A significant (p<0.05) decrease in superoxide dismutase (SOD) activity was observed in old mice brains compared with that of the young mice. malondialdehyde (MDA) content was significantly (p<0.05) increased in the old mice brain. However, any significant difference in SOD activity and MDA contents of the irradiated brain was not observed compared to age-matched control group mice. SOD activity and MDA content were observed within good parameters of brain aging and there were no late effects on the age-related oxidative level in the ${\gamma}-ray$ irradiated mice brains.

• 한국노년학
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• v.38 no.2
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• pp.309-327
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• 2018

Meta-analysis was conducted on 34 studies reported in Korea from February 2007 through March 2017 to systematically integrate factors of aging anxiety of the middle and old aged. The variables related to aging anxiety were divided into 6 groups of variable, and the effect sizes were computed for each variable of their groups. The results are as follows. First, the total effect size showed the middle effect size, and the effect size according to the variable group showed the largest effect size for the negative psychological variable group, followed by the positive psychological variable, the social variable, the physical variable, the familial variable and the demographic variable. Second, the largest effect size of the sub-variables showed psychological well-being and death anxiety. As described above, suggesting that these variables may have a strong influence on aging anxiety among the variables related to aging anxiety because the psychological well-being and death anxiety were shown as the largest effective variables related to aging anxiety.

• Journal of the Korean housing association
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• v.18 no.1
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• pp.95-102
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• 2007

As the aging of this society, instead of growing numbers old protective functions of families decreased according to increasing tendency of nuclear families, increasing rates of females' participation of economic activities. Now, the problem of supporting the old is in need of social supporting system the cope with this situation. Thus it needs that welfare service for the elderly who stay at home that have local basis. The results are based on these factors are like this: 1) It is necessarily the instruction of medical welfare service. 2) The overlapped service is avoided and the service of specialized. 3) Most of the welfare service institution is Seoul and local city hall, so it needs the institution is transferred. 4) It needs the increase the number of home helper. 5) When the service is offered, the government must considers finance, elderly health condition and preference. 6) It needs the department for the welfare service for the old who stay at home.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.23 no.1
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• pp.253-259
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• 2010

Objectives: We investigated $L^*a^*b^*$ and $ITA^{\circ}$ value on the face to correlate the complexion of Korean female with aging theory of Neijing(內經) in Suwen-Shanggutianzhenlun(素問,上古天眞論). Methods: Three hundreds and thirty one Korean females, aged 22-64 years($39.36{\pm}9.71$ years) were participated in this study. We measured the skin properties of the face with Spectrophotometer CM2600d(Minolta, Japan). Trisimulus $L^*a^*b^*$ color and $ITA^{\circ}$ value divided on 7 years were and analyzed by regression analysis method. Results: $L^*$, ITA value decreased and $a^*$, $b^*$ increased as the age increases. Among these, we found out that ITA value is most related to aging. $L^*$ value decreased among the group of 28 to 35 years old. ITA value decreased among the group of 35 to 42 years old. $a^*$ value decreased among the group of 42 to 49 years old. Conclusions: Unique aging pattern by 7 years of female in Oriental medicine is reflected to complexion.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.2
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• pp.1164-1174
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• 2015

This study examined the factors influencing aging anxiety in university students. The participants were 239 nursing students from one university in Seoul. Data were collected from September to December in 2014 and analyzed using descriptive statistics, Pearson's correlation coefficient, and multiple regression. The average score for aging-anxiety was 2.94, for knowledge about the elderly 18.92, for attitude toward the elderly 65.5, for participants' supporting awareness of old parents 4.05, and for self-esteem 3.07. There were negative correlations between aging anxiety, attitude toward the elderly, supporting awareness of old parents, and self-esteem. Aging-anxiety was significantly influenced by age, gender, living with grandparents, attitude toward the elderly, supporting awareness of old parents, and self-esteem. In view of the results of this study, one of the strategic ways to help college students reduce aging anxiety is to provide an opportunity to participate in activities that they can experience positive relationship with elderly.

• Proceedings of the Korean Society of Life Science Conference
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• 2000.06a
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• pp.9-10
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• 2000

The aging process is multifactorial and results from the combined effects of inherited(genetic) and acquired factors including life style, food habits, physical activity, and diseases. That give rise to the various approaches in aging. We are trying to study biological changes with aging, In detail we are focused on gene and protein function accompanied by normal or abnormal aging process, especially our efforts are aimed at revealing the functional relationship of proteins in aging as a final product of gene. We expect that proteomic approach to the study of protein function involved in aging should give us variety of integrated data to understand biological changes of long lived lives, We have applied expression proteomics to rat liver bred in dietary restriction or in at libitum to elucidate the effects of food habit on aging. Expression proteomics shows us protein profile in a selected tissue or cells as a whole and gives us the information about protein expression level, posttranslational modification and degenerative modification of expressed proteins. Comparative analysis of young and old rat liver by two dimensional gels shows that gene expression of several proteins was down regulated in old rats and some protein expression level is increased with aging. Dietary restriction slows down these changes of gene expression and in some proteins there's no difference in protein expression level at same ages in comparison with rats bred in at libitum. About forty protein was identified by peptide mass fingerprint with MALDI-TOF and rest of the protein of interest is in the course of identification, Also we are trying to make mitochondrial and cytosolic proteom reference map. These suborganelle proteom map will gives us the information about low abundance proteins and cellular localization of proteins. Proteomics is a growing methodology to study biological system. High throughput qualitative and qualitative aspect of this approach will gives us large amount of integrated information and speed up our understanding about biological system

• Journal of Korean Academy of Nursing
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• v.34 no.6
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• pp.1057-1068
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• 2004

Purpose: This study was conducted to identify the differences of health patterns; health-related characteristics, health behaviors, health problems, and self-care levels of elderly, living alone in an urban area according to age roup. Method: The study design was a descriptive survey and the subjects were 1,800 elderly consisting of 937 young old, 704 middle old, and 159 old old. Data was collected from May to July 2003 using the structured questionnaire and analyzed by descriptive statistics, $\chi$$^2$-test, Fisher's exact probability test, ANOVA and Scheffe test using SPSS/PC. Result: The health related characteristics which involved body mass index, mental status, use of assistant devices, perceived health, concern of health, and social support were different among the groups and more aggravated by aging. Health behaviors and health problems were also significantly aggravated in the old old group. The self-care levels measured by ADL, physical activity, and self-care ability scores were also significantly decreased in the old old group. Conclusion: For the level of health status, health behaviors and self-care ability were significantly decreased by aging, health care services for the elderly should be planned considering the difference in the health pattern by age group.

• The Journal of Korean Society for School & Community Health Education
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• v.20 no.3
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• pp.29-42
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• 2019

Objectives: This study aimed to examine the effect of successful aging on depression and social capital(trust, norm, participation, network) of the elderly. Methods: Samples were obtained from 184 people aged over 65 years old in one county of Kyungsangbukdo. Data were analyzed with t-test, ANOVA and regression analysis. Results: First, depression, social capital and successful aging were significantly different by age, economic status and religion. Secondly, regression analysis showed that depression affected a negative influence on successful aging in Model 1, which analyzed only depression. However, Model 2, which analyzed depression and social capital at the same time, showed that only social capital affected successful aging. Conclusions: It was suggested to develop health promotion and social participation program are required for successful aging of the elderly.

• Journal of Society of Preventive Korean Medicine
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• v.8 no.1
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• pp.155-161
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• 2004

The average life span is expanded due to the development of modem society, material and cultural life and increasing level of public health. This means that the aging society is rapidly progressing. Geniatric diseases also have increased due to increasing of the aged population. Along with an increase of the aged patient, the anti-aging, prevention of geniatric disease and quality of life is tending high on social concern and medical issues. Many reports showed the evidence to the positive anti-aging effect of Oriental medicine. Qigong therapy, a kind of Oriental medicine, has been used to prevent aging and life prolongation with positive effect for many thousand years. Therefore, qigong practice is popular and common to middle age and old age in China.

• Journal of the Korean Solar Energy Society
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• v.39 no.2
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• pp.45-55
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• 2019

More than 76% of the detached houses in Korea are over 20 years old. These old detached houses have poor energy efficiency. According to the 2017 Housing Census (Statistics Korea), more than 50% of low-income families live in detached houses. Therefore, the improvement of energy efficiency in old detached houses is needed from the viewpoint of energy welfare. The general method of building energy modelling for the verification of energy efficiency is based on the construction year data of "Building Design Criteria for Energy Saving" due to the cost and time involved in collecting the thermal performance data of buildings. There is poor accuracy with the deterioration of long-term aging of building materials. Also, the selection of alternatives for energy performance improvement is based on the items to be applied, not a performance improvement goal. It is difficult to calculate energy performance that reflects variations in various parameters with dynamic energy simulations. In this study, the influence of long-term aging is used to accurately predict the energy performance of old detached houses. The building energy modelling method is called ENERGY#, which is a static analysis method based on ISO13790. Energy performance is evaluated by a combination of input variables including building orientation, insulation of walls and roof, thermal performance of windows and window/wall ratio, and infiltration rate. Finally, this study provides a way to determine alternatives that meet energy performance improvement goals.