• Journal of Menopausal Medicine
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• v.24 no.3
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• pp.176-182
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• 2018

Objectives: Menopause is associated with adverse metabolic changes in plasma lipoprotein and inflammation markers. Estrogens have beneficial effects on lipid metabolism and inflammation. Isoflavones (ISO) have structurally similar to estradiol. Our objective was analize the effect of soy-ISO on serum lipid and inflammatory markers (sP-selectin and sCD40L) in postmenopausal women. Methods: A 12-week randomized, double-blind, placebo-controlled intervention with soy-ISO (50 mg, twice daily) was conducted in 35 healthy postmenopausal women (55-72 years old). The women were divided in 2 groups: 20 were allocated to soy-ISO, and 15 to a placebo group. Results: The changes of total cholesterol (TC), triglycerides, low-density lipoproteins-cholesterol (LDL-C), high-density lipoprotein-cholesterol, Apo-A1, sP-selectin and sCD40L in 2 groups before and after 12-week treatment showed no statistical significance. In subgroup analysis, soy-ISO supplementation significantly decreased the levels of TC, LDL-C and sCD40L in women under 65 years old, and with null effects on serum lipid and inflammation markers in women over 65 years old. Conclusions: Soy-ISO did not significantly favorable effects on the lipid profile and inflammatory markers in postmenopausal women. However, in women under 65 years of age, soy-ISO significantly decreased the TC, LDL-C and sCD40L, whereas, no effects on lipid profile and inflammation markers in women over 65 years old were observed.

• 한국노년학
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• v.30 no.4
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• pp.1409-1427
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• 2010

The purpose of this study is to understand volunteer work experiences of senior citizen volunteers serving in the welfare center in K district in the aspect of an insider and to apprehend the meaning. The objects of this study are fifteen senior citizen volunteers and two social workers who do volunteer works in the welfare center, and this study utilized the qualitative study method through observations and in-depth interviews from 2009.09.02 to 2009.10.21. The data analysis is processed by the qualitative analysis program, Nvivo 2.0, and the processed data are analyzed in accordance with the grounded theories of Strauss and Corbin. As a result of reviewing data, the meanings about volunteer work experiences of senior citizens are induced as eight factors; senior citizens' identity in an old aging society, desire fulfillment through volunteer works by senior citizens, various leisure activities to help their health in mind and body, acceptance attitude about aging, mental supports from their families, finding activities suitable for each person's personality and capability, changes of perception about the handicapped, and endeavors to spend meaningful old age. Through results and discussion obtained by this study, the conclusion is as below: First, participation induction factors are identities of elderly people in aging society, acceptance attitudes toward aging and emotional support from families in the matter of senior citizens' volunteer work. Second, programs suitable for individual aptitude and capability should be implemented for activating senior citizens' volunteer work. Third, participation in senior citizens' volunteer work indicates desire satisfaction through senior citizens' volunteer work, leisure activities helping health for body and mind, and life changes such as changes of perception about handicapped people etc.

• Journal of Physiology & Pathology in Korean Medicine
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• v.33 no.2
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• pp.89-101
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• 2019

In recent times, the number of men with late-onset hypogonadism has increased, and interest on this topic has also increased. This study was conducted to investigate effects of the mixture extract of Fructus amomi Amari, Eucommiae cortex, Bombyx batryticatus on improve late-onset hypogonadism. The experimental subjects consisted of three groups: a control group consisting of 8-week-old male ICR mice that had undergone no treatment, an aging-elicited group (AE group) consisting of 50-week-old ICR male mice that had undergone no treatment, and a Mixed herbal extract treatment group (MT group) consisting of 50-week-old ICR male mice that had undergone the mixture extract of Fructus amomi Amari, Eucommiae cortex, Bombyx batryticatus treatment (0.1 g/kg/day) for 6 months. After the experiment, the mice from all the experimental groups were dissected, and they were analyzed through histochemical and immunohistochemical methods. The mixture extract of Fructus amomi Amari, Eucommiae cortex, Bombyx batryticatus reduces aging-induced cell damage and oxidative stress and increases the secretion of serotonin and B-endorphin in aged mice, and promotes spermatogenesis in seminiferous tubules and reduces apoptosis and oxidative stress, and increases androgen receptor, $17{\beta}-HSD$ and GnRH, increases the ratio of smooth muscle to collagen fibers in the corpus cavernosum, increases eNOS, decreases PDE-5 and oxidative stress in aged mice, so it improves depression, reproductive, sexual problems caused by Late-onset hypogonadism. the mixture extract of Fructus amomi Amari, Eucommiae cortex, Bombyx batryticatus inhibits the induction of osteoporosis by increasing decreased bone matrix distribution due to aging, increasing the activities of OPC and OPN, which are produced in osteoblasts, and decreasing RANKL, MMP-3 activity, increasing OPG activity. It also reduces muscle damage, oxidative stress, inflammation and apoptosis of muscle tissue, and increases Myo-D in the sartorius muscle of aged mice for improving muscle atrophy caused by by Late-onset hypogonadism.

• Journal of the Korea Convergence Society
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• v.8 no.10
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• pp.351-358
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• 2017

This study analyzed the process of mourning for aging in the film 'Miss Granny' in a convergent method. In exploring the contents of the movie repeatedly and interpreting the feeling of loss of old age in aging process as mourning process, I explored them in a psychoanalytic way. In other words, in a psychoanalytic method, I analyzed the aging process as a process of reinterpreting life and the change in developmental attitude toward the future life as a psychological world of mourning. The results of the study show that the process of mourning follows 'loss and deficiency', 'escape and regression', 'disidentification and decentralization', and 'adaptation to the new reality'. Based on these results, this research suggests that the counselor should not only focus on creating a psychological mood environment so that the client's mourning work will be smooth, but also should be able to use a complex counseling technique to improve the mental ability of the client.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.31 no.3D
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• pp.391-401
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• 2011

The Implementation Semi-Public Management System of Intra-City Bus brings improvements of the position stability, work environment and welfare of the bus drivers. As these benefits prevent drivers' job changes, average age of the drivers increases. Some side effects such as fatality increase after the implementation of the new system are becoming social problems. To minimize such problems, it is necessary to prepare the measurements reflected drivers' age increase and driving characteristics of old drivers to decrease traffic accidents of intra-city buses. The existing measurements are mostly simple policy. To get over such limitations, this study grasped driving characteristics by surveys and driving aptitude test targeting old drivers and non-old drivers who brings about traffic accidents actually. As a result, the characteristics of the old drivers were understood precisely. The measures of decrease of the traffic accidents are suggested by the analysis of the behavior characteristics of the old drivers through the structural equation model.

• Journal of The Korea Institute of Healthcare Architecture
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• v.4 no.7
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• pp.31-38
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• 1998

Korea is facing the problems of old aging society recently. In the future the ploblems will become more serious. Specially health care services for the aged are very poor in the aspect of both systems of services and supplies of facilities. This paper aims to identify the types as well as present statistical conditions of health care facilities for the aged in Korea.

• 한국정보디스플레이학회:학술대회논문집
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• 2009.10a
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• pp.163-165
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• 2009

It is commonly found that liquid crystals stored in a common environment degrade with time, trapping more and more ion impurity in the materials. In this paper, we demonstrate how the electrical property of an old batch of liquid crystal can be effectively restored by a novel regenerative agent.

• Development and Reproduction
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• v.11 no.1
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• pp.13-20
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• 2007

In all female mammals, reproductive system is one of the first biological systems to show age-related decline. Female mammals in reproductive aging, though the phenomena is somewhat species-specific, start to show declining fertility and changes of numerous physiological functions. This review will present a current information on the aging of the female reproductive hormonal axis and introduce three useful rodent models for studying this field. Middle age($8{\sim}12$ months old) in female rats and mice is comparable to the stage prior to the entry of menopause in human. In this period pulsatile and surge GnRH secretion from hypothalamus gradually attenuated, then reduced pulsatile and surge LH secretion is followed consequently. This age-related defects in GnRH-LH neuroendocrine axis seem to be highly correlated with the defects in brain signals which modulate the activities of GnRH neuron. Many researchers support the idea which the age-related hypothalamic defects are the main cause of reproductive aging, but some ovarian factors such as inhibin response also could contribute to the induction of reproductive senescence. Some rodent models are quite valuable in studying the reproductive aging. The follitropin receptor knockout(FORKO) mice, both of null and haploinsufficient state, could produce depletion of oocyte/follicle with age. Dioxin/aryl hydrocarbon receptor(AhR) knockout mice also show severe ovarian defects and poor reproductive success early in their life compared to the age-matched normal mice. Further studies on the reproductive aging will be a great help to evaluate the benefits and risks of hormone replacement therapy(HRT) and to improve the safety of HRT.

• Korean Journal of Family Social Work
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• no.54
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• pp.187-224
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• 2016

This study aims to investigate the effect of psychosocial aging on age integration and the moderating effect of Familism and Family solidarity. In particular, this study has significance for establishing a basis of practical and political intervention in family level for improving age integration. We employed data from the 'Ageing Society Awareness Investigation' funded by Korean National Research Foundation in 2014. Our analysis sample consisted of 702 adults who were from 40 to 90 years old. Also, this study conducted descriptive statistics and multiple regression analysis by using STATA13. First of all, the lower psychosocial aging awareness is the higher age integration awareness. Familism and family solidarity were not a significant predictor for age integration. However, the interaction effects between familism as well as family solidarity and psychosocial aging ware statistically associated with age integration. That is to say that as psychosocial aging is negative, when decrease age integration, the net moderating effects of familism and family solidarity were found between age integration and psychosocial aging. Based on the results, this study provides implications that reinforcing family value and promoting interaction and solidarity with family members are positively contributed to age integration awareness at this point of negative psychosocial aging.

• Korea journal of population studies
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• v.29 no.3
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• pp.139-157
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• 2006

This study presents limitations of the old family supported system for the elderly being surfaced in the face of the changing life style of the people in today's industrialized, urban Korean society. The qualitative data used for this study are collected from the focus group discussions(FGD). The FGD data numbered a total of 43 participants who were divided into 8 different groups, each consisting of 5-6 respondents sorted out by sex and age as well as by their current cohabitation with their parents or having such experience in the past. The study paid special attention focusing on the values and the expectations regarding the elderly support and the family relationship. A critical reexamination of the old family support system for the elderly at this particular juncture is also a step forward necessary for the eventual formulation of policy measures by the state and the society to produce a new viable support system for the elderly in the future.