• Journal of Acupuncture Research
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• v.28 no.2
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• pp.97-105
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• 2011

Objectives : The aim of this experiment is to know the effect of mountain cultivated ginseng pharmacopuncture on heart rate variability(HRV), pulse wave velocity(PWV) in middle aged women. Methods : We investigated on 20 healthy Middle Aged women volunteers. First, we measured their heart rate variability(HRV), pulse wave velocity(PWV) and then mountain cultivated ginseng pharmacopuncture 20cc were injected on them. After 30 minutes, we measured heart rate variability(HRV), pulse wave velocity(PWV) again. As a result, method of one-group pretest-posttes design were used for evaluation. Results : 1. In HRV, MeanHRV is significantly decreased from 69.15 to 63.34 after injection. 2. MeanRR is significantly increased from 877.20 to 962.10 after injection. SDNN is significantly increased from 32.56 to 41.34 after injection. 3. PNN50 is significantly decreased after injection. RNSSD, SDSD, TP, VLF is significantly increased after injection. 4. Stress resistance ability is significantly increased from 37.55 to 44.60 after injection. 5. In PWV, E-R, E-L, H-R, H-L is significantly decreased after injection. Conclusions : Effect of mountain cultivated ginseng pharmacopuncture on heart rate variability(HRV) increased adaptability of autonomic nervous system and on pulse wave velocity(PWV) decreased arterial stiffness.

• Journal of Life Science
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• v.19 no.10
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• pp.1403-1409
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• 2009

The purpose of this study was to compare Obesity Age (OA) and chronological age, to calculate Obesity Age (OA), which gauges the state of obesity, and to analyze presented factors of obesity using expectant factors on middle-aged obese women. The subjects were one hundred twenty seven middle-aged obese women ($49.6\pm7.3$ yr, BMI $29.41\pm2.9$, fat $36.8\pm4.6%$) who participated in different weight loss programs three times. The body composition, physical fitness, blood pressure and blood were measured before the weight loss programs. Informed consent was obtained from all subjects before enrollment in the study. The regression equation is as follows: (1) OAS (Obesity Age Score)=$0.106*X_1+0.035*X_2+0.048*X_3+0.041*X_4+0.003*X_5-0.037*X_6-10.667$ ($X_1$: BMI, $X_2$: weight, $X_3$: %fat, $X_4$: WC, $X_5$: TG, $X_6$: $VO_{2max}$), (2) OA (Obesity Age)=7.3*OAS+49.6*(-1), (3) Z (correction factor)=(CA-49.6)(1-0.03), (4) OAc (corrected Obesity Age)=1.03*CA-7.3*OAS+1.47. The comparison of corrected Obesity Age (OAc) and chronological age did not have any differences, and the average of the OAc was close to chronological age. The correlation coefficient between the OAc and chronological age was r=0.724 (p<0.05). The equation can be utilized for middle-aged obese women, because it could evaluate the obesity-related factors by including BMI, body weight, %fat, waist circumference, triglycerides and $VO_{2max}$.

• Korean Circulation Journal
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• v.54 no.9
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• pp.534-544
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• 2024

Background and Objectives: Lipid lowering therapy is essential to reduce the risk of major cardiovascular events; however, limited evidence exists regarding the use of statin with ezetimibe as primary prevention strategy for middle-aged adults. We aimed to investigate the impact of single pill combination therapy on clinical outcomes in relatively healthy middle-aged patients when compared with statin monotherapy. Methods: Using the Korean National Health Insurance Service database, a propensity score match analysis was performed for baseline characteristics of 92,156 patients categorized into combination therapy (n=46,078) and statin monotherapy (n=46,078) groups. Primary outcome was composite outcomes, including death, coronary artery disease, and ischemic stroke. And secondary outcome was all-cause death. The mean follow-up duration was 2.9±0.3 years. Results: The 3-year composite outcomes of all-cause death, coronary artery disease, and ischemic stroke demonstrated no significant difference between the 2 groups (10.3% vs. 10.1%; hazard ratio [HR], 1.022; 95% confidence interval [CI], 0.980-1.064; p=0.309). Meanwhile, the 3-year all-cause death rate was lower in the combination therapy group than in the statin monotherapy group (0.2% vs. 0.4%; p<0.001), with a significant HR of 0.595 (95% CI, 0.460-0.769; p<0.001). Single pill combination therapy exhibited consistently lower mortality rates across various subgroups. Conclusions: Compared to the statin monotherapy, the combination therapy for primary prevention showed no difference in composite outcomes but may reduce mortality risk in relatively healthy middle-aged patients. However, since the study was observational, further randomized clinical trials are needed to confirm these findings.

• Journal of the Korean Applied Science and Technology
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• v.37 no.2
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• pp.354-361
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• 2020

The purpose of this study was to investigate the effects of regular taekwondo training on neurotrophic factors and cognitive function in obese middle-aged women. Thirty-three middle-aged women with obesity were selected for this study and randomly assigned into a control group(CG, n=18) and an taekwondo group(TG, n=15). The TG performed taekwondo training 5 times weekly for 16 weeks, while the CG did not exercise training. Serum brain-derived neurotrophic factor(BDNF), vascular endothelial growth factor(VEGF), and insulin-like growth factor-1(IGF-1) levels were analyzed and Stroop Color and Word tests were performed before and after the intervention. The serum BDNF and IGF-1 levels were significantly increased in the TG after the intervention(p<.05). On the other hand, no statistically significant differences were found in the serum VEGF levels, or in the Stroop Color and Word Test scores(p>.05). These results suggest that regular taekwondo training may be affects levels of peripheral neurotrophic factors but not cognitive function in obese middle-aged women.

• Journal of the Korean Dietetic Association
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• v.9 no.4
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• pp.307-315
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• 2003

This study was to investigate the relation of nutrients intake, health status, and bone mineral density in middle-aged women. Daily nutrients intake were analyzed by convenient method. The BMD of subjects were measured by Dual Energy X-ray Absorptiometry(DEXA). BMD was measured at the spine(vertebrae L2-L4) and femur(neck, Ward's triangle and trochanter). The nutrients intake of subjects were higher than recommended dietary allowances(RDA) except for calorie, iron, calcium, vitamin B1. Nutrients intake of vitamin A(p<0.05), iron(p<0.01), vitamin $B_2$(p<0.05), niacin(p<0.05), and vitamin C(p<0.05) between $\leq$49 yr group and $\geq$50 yr group. Mean daily intake of calcium was much less than the Korean RDA, 78.5% in $\leq$49 yr group and 77.3% in $\geq$50 yr group. 35.8% of the subjects under 50 years of age($\leq$49 yr group) and 77.4% of the subjects from 50 years up($\geq$50 yr group) were classified as osteopenia or osteoporosis. BMD of L2-L4 were positively correlated with height(p<0.05), weight(p<0.05) and BMI(p<0.05). BMD of femoral neck was positively correlated with BMI(p<0.05), BMD of Ward's triangle was positively correlated with weight(p<0.001). But BMD of L2-L4 and femoral neck were negatively correlated with age(p<0.05), menarche(p<0.05). BMD of Ward's triangle was negatively correlated with age(p<0.001). The BMD of L2-L4 were positively correlated with animal protein(p<0.05), calcium(p<0.05) and iron(p<0.05). The BMD of femoral neck was positively correlated with animal protein(p<0.05). The BMD of Ward's triangle was positively correlated with animal protein(p<0.001) and iron(p<0.001). The above results suggest that it should be difficult to prevent middle-aged women's bone destruction through nutrients intake. Further investigation is necessary to prove the mutual relations between BMD, exercise, and calcium intake. Therefore, middle-aged women will need proper exercise as well as Ca supplementation in order to prevent osteoporosis with aging.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.5
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• pp.582-593
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• 2016

This study is a qualitative one that used a phenomenological study method to provide basic data for nursing practice by understanding the essence and meaning of middle aged men's hemiplegic experience after stroke. At D hospital which is located in S city, 8 hemiplegic participants who were hospitalized between 24th November, 2014, and 6th December, 2014, participated in in-depth interviews. The experiences of the participants were categorized into 6 criteria, viz. 'Thorny path on a long journey', 'Broken brakes', 'Crossroads of the mind', 'Burden of head of household', 'Signpost that lights the darkness', and 'Route to a second life', and 16 theme clusters were included in these categories. As the sequelae and complications, such as physical pain, psychological conflict and role disorder, due to stoke in middle aged men, seriously affect their quality of life, this study attempted to understand the effect of these problems and provide new insight into nursing practice. Also, it is important to prevent the recurrence of stroke in the patients, facilitate their recovery, and help them to maintain healthy lives through the reestablishment of their role in the home and society, including through the resolution of their physical and psychological problems.

• Journal of the Korea Convergence Society
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• v.12 no.7
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• pp.69-82
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• 2021

This study targeted 4,572 middle-aged women to examine the relationship between nutritional status and dietary inflammatory index according to blood glucose level using data from the Korean National Health and Nutrition Examination Survey (KNHANES). Data were analyzed using complex survey chi-square, General Linear Model and logisitc regression in SPSS Win 25.0 program. Women with high blood glucose (normal blood sugar→diabetes) had high rates of obesity and blood TG/HDL-cholesterol ratio. On the other hand, the Mean Adequacy Ratio (10 nutrients) and the intake of anti-inflammatory foods: beans, seeds, mushrooms, and fruits, were lower in the diabetic category. When we analysed the association between blood glucose and the Dietary Inflammatory Index, the risk of pre-diabetes and diabetes was significantly higher in the most pro-inflammatory diet category (Q5) compared to the most anti-inflammatory diet category (Q1). These findings suggest that nutritional education emphasizing the intake of various foods should be effectively conducted effectively in order to improve blood glucose among middle-aged women.

• Journal of Labour Economics
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• v.37 no.3
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• pp.101-122
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• 2014

This paper empirically estimates the decision of aged workers related to the retirement decision. Using the supplemental survey for aged people of the Korean panel data set, the paper analyses the correlation between the retirement decision of middle-aged people (aged 50 years or older) and personal characteristics and job characteristics of main jobs that aged people had worked, particularly focusing on the mandatory job retirement regulation and its regulation of retirement ages. The empirical results show that the regulated retirement age is more important than the existence of mandatory retirement system in related to the workers' retirement decision.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.4 no.2
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• pp.1-19
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• 2009

American Psychiatric Association defined hwa-byung as a unique mental illness of Korea, a kind of anger syndrome. This illness caused by the Korean culture is more often found on women than men, especially middle-aged women. The cause of hwa-byung mainly depends on the traditional family structure of Korea formed by Confucianism. Other causes that many middle-aged women suffer from hwa-byung are that their low education level originated in their wrong-recognized position in society and poverty in the past makes them not to be able to control their minds effectively(social psychological factor), and that they get stressed and depressed because of loss of their position in the family after their children leave home and the menopause which hurts their feminine beauty (physiological factor). So, this program aims at letting them to; 1) experience catharsis of the negative feelings which causes hwa-byung by expressing in psychodrama, 2) ease the symptoms of hwa-byung by relaxing their mind, 3) understand themselves through sharing their feelings and thinking at the group level, 4) acquire the opportunities to stabilize and expand their role in their real lives through the role playing.

• Journal of Obesity & Metabolic Syndrome
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• v.25 no.3
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• pp.138-148
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• 2016

Background: The purpose of this study is to analyze the effects of an abdominal obesity management program in middle-aged women in Korea. Methods: Examination of databases, including the Research Information Sharing Service, Database Periodical Information Academic, and Korean Studies Information, resulted in identification of 772 studies performed up to 2014, of which 43 satisfied the inclusion data. Data analysis was performed using R version 3.2 to calculate the effect sizes, explore possible causes of heterogeneity, and check for publication bias, using a funnel plot and its trim-and-fill analysis. Results: The mean effect size of the management program was small (g=0.22), along with the anthropometric index (g=0.18), metabolism index (g=0.21), fat-distribution (g=0.36), and inflammatory index (g=0.36). Moderator analysis was performed to determine heterogeneity, but no significant differences were found between the randomized controlled trial (RCT) group and non-RCT group. In addition, the length of the session was found to be statistically significant after performing a meta-regression. Finally, a funnel plot with a trim-and-fill analysis was produced to check for publication bias, but no significant bias was detected. Conclusion: Based on these findings, the abdominal obesity management program affects middle-aged women in Korea. Further research is needed to target other age groups with abdominal obesity.