• Title/Summary/Keyword: The change in the duration

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The Effects of Irritating Spices on Drug Metabolizing Enzyme Activity -Effects on Hexobarbital Hypnosis in Mice- (자극성(刺戟性) 향신제(香辛劑)의 약물대사효소활성(藥物代謝酵素活性)에 미치는 영향(影響) -마우스의 Hexobarbital 수면시간(睡眠時間)에 미치는 영향(影響)-)

  • Woo, Won-Sick;Shin, Kuk-Hyun;Kim, In-Chull
    • Korean Journal of Pharmacognosy
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    • v.8 no.3
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    • pp.115-119
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    • 1977
  • Black pepper (Piper nigrum L.) among several irritating spices tested was highly effective on the duration of hexobarbital hypnosis in mice. Pretreatment of mice with the methanolic extract of black pepper (60mg/kg i.p.) prolonged markedly the duration of hexobarbital sleeping time. Three consecutive daily administrations of the same dose of black pepper extract, however, shortened (37%) the duration of hexobarbital sleeping time. The ether soluble fraction of black pepper extract caused most potent effects on the duration of hexobarbital hypnosis. From the above results, it was postulated that the lipid soluble components of black pepper might considerably change the drug action and metabolism by altering drug metabolizing enzyme systems.

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The Research about Engine Speed change Effect on HCCI Engine Combustion by Numerical Analysis (엔진회전속도의 변화가 HCCI엔진연소에 미치는 영향에 관한 수치해석 연구)

  • Lim, Ock-Taeck
    • Journal of ILASS-Korea
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    • v.16 no.3
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    • pp.126-133
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    • 2011
  • In HCCI Engine, combustion is affected by change of compression speed corresponding to engine speed. The purpose of this study is to investigate the mechanism of influence of engine speed on HCCI combustion characteristics by using numerical analysis. At first, the influence of engine speed was shown. And then, in order to clarify the mechanism of influence of engine speed, results of kinetics computations were analyzed to investigate the elementary reaction path for heat release at transient temperatures by using contribution matrix. In results, as engine speed increased, in-cylinder gas temperature and pressure at ignition start increased. And ignition start timing was retarded and combustion duration was lengthened on crank angle basis. On time basis, ignition start timing was advanced and combustion duration was shortened. High engine speed showed higher robustness to change of initial temperature than low engine speed. Because of its high robustness, selecting high engine speed was efficient for keeping stable operation in real engine which include variation of initial temperature by various factors. The variation of engine speed did not change the reaction path. But, as engine speed increased, the temperature that each elementary reaction would be active became high and reaction speed quicken. Rising the in-cylinder gas temperature of combustion start was caused by these gaps of temperature.

A Study on Bergson's Simultaneity Revealed in Modern Spaces (현대 공간에서 나타나는 베르그송의 동시성 연구)

  • Lee, Sang-Jun;Lee, Chan
    • Korean Institute of Interior Design Journal
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    • v.24 no.4
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    • pp.51-60
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    • 2015
  • This study aims to establish the foundation for a simultaneity research, draw the potential through Bergson's simultaneity, and explore a space with the possibility of a continued change, focusing on the simultaneous process, in which physical mobility and consciousness of space last together. First, this study was focused on understanding Bergson's simultaneity, on the basis of the perspective that space needs to have more active, dynamic mobility. For understanding Bergson's simultaneity, the understanding of Bergson's duration conception, memory and perception was preceded. After that, the characteristics of simultaneity were extracted from the concepts of duration, change, memory and perception and its characteristics, which are connected to space, were analyzed. As a result, the study on simultaneity that was intensively analyzed, based on diverse cases, re-awakened the basis of value or thought, which we must aim at, in space design of the present time. This shows the possibility of another creative form that can be found in spaces of the present time and serves as the foundation to discover an essential and potential value of space in space design. Moreover, the combination of space with science, humanities, art and digital media technology demonstrated once again that there is a good possibility of approaching non-representational space that is pursued today and it is anticipated that using Bergson's simultaneity as a medium for spatial combination in their relationship would help in drawing deeper internal meaning and potential of space.

A Study on the Duration of Cover in the Institute Cargo Clauses 2009 (2009년 협회적하약관상 보험기간에 관한 연구)

  • Shin, Gun Hoon;Lee, Byung Mun
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.59
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    • pp.81-112
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    • 2013
  • This article intends to examine main features of revision in relation to the duration of cover in the Institute Cargo Clauses 2009 and the results of analysis are as followings. First, the cover, which had been "warehouse to warehouse", has been extended to what may be called "shelf to unloading". Thus the insurance attaches when the goods are first moved within the warehouse or place of storage at the named place for the purpose of immediate loading for the commencement of transit. Secondly, the new termination Clause 8.1.3 requires an election by the assured, or their employees, to use a vehicle or container, for storage other than in the ordinary course of transit. Thirdly, Clause 10.1, which deals with the assured's voluntary change of voyage, was amended to solve the problem that the words "held covered" could be misunderstood by an assured without specialist knowledge of English marine insurance law to be a guarantee of cover, even where cover would not be commercially available. Finally, Clause 10.2 is designed to solve the so-called "phantom ship problem", arising from the harsh decision in The Prestrioka. The new Clause 10.2 provides protection for an innocent assured in the situation of a phantom ship.

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A Study on the character of Urban Entertainment Center in multi-anchor and exposure time - Focusing on Cheongryanri station and Yongsan station - (집객시설과 노출시간에 따른 도심 엔터테인먼트형 복합상업시 설(UEC)의 특징에 관한 연구 - 청량리역과 용산역을 중심으로 -)

  • Kim, Hyeongjung
    • Korean Institute of Interior Design Journal
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    • v.22 no.1
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    • pp.283-290
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    • 2013
  • The change of shopping environment created new emerging type of shopping center after 1990's, Urban Entertainment Center(UEC) in northen America. One hand traditional shopping center was retail-centered, the other hand UEC is entertainment-centered and offers the trinity of synergy. Each components, that are retail, dining and entertainment, play a role of drawing people, extending duration of visiting and making people revisit then the synergy makes commercial profit in shopping center. As northen America many of shopping centers with complex have been built in Korea since 2000 and some projects is planning by the change of shopping environment and regenerating urban. Although the term of "UEC" is used in Korea, it seems to be added entertainment facilities to shopping center without considering on commercial strategy. This study will take a look at mix and duration of visit which ULI stresses in UEC development and comparing with those of Yongsan Station and Chyeongrangri Station which are built recently in seoul, it will get characters and situation of these UECs. Finally, the analysis is to be used as a planning data in UEC development.

A study on characteristics of crystallization according to changes of top structure with phase change memory cell of $Ge_2Sb_2Te_5$ ($Ge_2Sb_2Te_5$ 상변화 소자의 상부구조 변화에 따른 결정화 특성 연구)

  • Lee, Jae-Min;Shin, Kyung;Choi, Hyuck;Chung, Hong-Bay
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2005.11a
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    • pp.80-81
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    • 2005
  • Chalcogenide phase change memory has high performance to be next generation memory, because it is a nonvolatile memory processing high programming speed, low programming voltage, high sensing margin, low consumption and long cycle duration. We have developed a sample of PRAM with thermal protected layer. We have investigated the phase transition behaviors in function of process factor including thermal protect layer. As a result, we have observed that set voltage and duration of protect layer are more improved than no protect layer.

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Analysis of extreme cases of climate change impact on watershed hydrology and flow duration in Geum river basin using SWAT and STARDEX (SWAT과 STARDEX를 이용한 극한 기후변화 사상에 따른 금강유역의 수문 및 유황분석)

  • Kim, Yong Won;Lee, Ji Wan;Kim, Seong Joon
    • Journal of Korea Water Resources Association
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    • v.51 no.10
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    • pp.905-916
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    • 2018
  • The purpose of this study is to evaluate the climate change impact on watershed hydrology and flow duration in Geum River basin ($9,645.5km^2$) especially by extreme scenarios. The rainfall related extreme index, STARDEX (STAtistical and Regional dynamical Downscaling of EXtremes) was adopted to select the future extreme scenario from the 10 GCMs with RCP 8.5 scenarios by four projection periods (Historical: 1975~2005, 2020s: 2011~2040, 2050s: 2041~2070, 2080s: 2071~2100). As a result, the 5 scenarios of wet (CESM1-BGC and HadGEM2-ES), normal (MPI-ESM-MR), and dry (INM-CM4 and FGOALS-s2) were selected and applied to SWAT (Soil and Water Assessment Tool) hydrological model. The wet scenarios showed big differences comparing with the normal scenario in 2080s period. The 2080s evapotranspiration (ET) of wet scenarios varied from -3.2 to +3.1 mm, the 2080s total runoff (TR) varied from +5.5 to +128.4 mm. The dry scenarios showed big differences comparing with the normal scenario in 2020s period. The 2020s ET for dry scenarios varied from -16.8 to -13.3 mm and the TR varied from -264.0 to -132.3 mm respectively. For the flow duration change, the CFR (coefficient of flow regime, Q10/Q355) was altered from +4.2 to +10.5 for 2080s wet scenarios and from +1.7 to +2.6 for 2020s dry scenarios. As a result of the flow duration analysis according to the change of the hydrological factors of the Geum River basin applying the extreme climate change scenario, INM-CM4 showed suitable scenario to show extreme dry condition and FGOALS-s2 showed suitable scenario for the analysis of the drought condition with large flow duration variability. HadGEM2-ES was evaluated as a scenario that can be used for maximum flow analysis because the flow duration variability was small and CESM1-BGC was evaluated as a scenario that can be applied to the case of extreme flood analysis with large flow duration variability.

Effects of Electro-acupuncture's Stimulated Frequency, Intensity, Duration at ST36 on the Small Intestine Motility in Rats (족삼리(足三里) 전침(電鍼)의 주파수(周波數), 강도(强度) 및 자극(刺戟) 시간(時間)이 소장(小腸) 수송능(輸送能)에 미치는 영향(影響))

  • Kim, Yong-Jeong;Park, Sang-Moo;Cha, Suk;Yun, Jeong-Ahn;Yu, Yun-Jo;Kang, Byung-Ki;Kim, Kang-San
    • Journal of Acupuncture Research
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    • v.23 no.4
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    • pp.175-185
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    • 2006
  • Objectives : This study was designed to investigate effects of electro-acupuncture's stimulated frequency, intensity, duration at 5736 on tile Small Intestine Motility in Rats. Methods The motor activity of small intestine in rats was evaluated by intestinal transportation rate. Changes in tile motility of ileum in vivo was measured at 10 minutes after electro-acupuncture. Various kinds of stimulus-frequency were used in this experiment: 2 Hz, 50 Hz, 100 Hz, 2 Hz-4 trains, 8 Hz groups treated with EA of the condition in S mA, 1 ms pulse duration, 30 minutes stimulated duration. Three different stimulus-intensity were used: 1, 5, 10 mA groups treated with EA of the condition in 2 Hz, 1 ms pulse duration, 30 minutes stimulated duration. Six different stimulus-duration were used: 10, 20, 30, 40, 50, 60 minutes groups treated with EA of the condition in 2 Hz, 5 mA, 1 ms pulse duration. Results : 2 and 100 Hz groups significantly increased the small intestine motility, but 50 Hz group did not induce a significant change. Besides, small intestine motility was significantly increased only in 5 mA intensity (5 times twitch). futhermore, at least 20 minutes EA treatment was necessary to increase the small intestine motility. Conclusion : Those basic data form this study can be applied to established the effective treatment of EA for gastrointestinal diseases in the clinical field.

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A Comparative Study of Listener Perception of Durational Change in the Korean Auxiliary Particle '-yo' (보조사 '-요'의 음장 변화에 따른 청자의 지각 차이 비교)

  • Yoon, Eun-Kyung;Kim, Sul-Ki
    • Phonetics and Speech Sciences
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    • v.3 no.4
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    • pp.55-62
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    • 2011
  • This paper investigates whether listeners perceive a different level of politeness when the duration of the Korean sentence-final auxiliary particle '-yo' is varied. A total of 10 Korean sentences were manipulated by lengthening and shortening '-yo' by 10%, 20%, and 30%. The participants included native Korean speakers and Chinese and Japanese learners of Korean (n=10, respectively). They were asked to rate the level of politeness of the stimuli on a 9-point scale. It was found that Korean listeners perceived decreased politeness as the duration of '-yo' was shortened and increased politeness as it was lengthened. However, Chinese and Japanese listeners did not perceive a different level of politeness from the manipulated sentences. This finding suggests that it is important to teach L2 speakers that the duration of the auxiliary particle '-yo' plays a role in Korean listeners' perception of politeness.

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The Effect of Hormone Replacement Therapy for Cognitive Function of Postmenopausal Depression (단기 호르몬 병합 치료가 폐경 후 우울증 환자의 인지 기능에 미치는 영향)

  • Lee, Sang Hoon;Ko, Young-Hoon;Joe, Sook-Haeng;Jung, In-Kwa;Kim, Seung-Hyun;Lee, Moon-Soo
    • Korean Journal of Biological Psychiatry
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    • v.12 no.2
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    • pp.173-180
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    • 2005
  • Purpose:We investigated the effect of menopausal duration on cognitive function using adjunctive hormone replacement therapy(HRT) in postmenopausal women with depression. Method:Twelve postmenopausal women with depressive disorder were enrolled. Six patients having menopausal duration of less than 3 years was assigned to the short duration group and six patients of more than 3 years to the long duration group. Each patient was treated with conjugated equine estrogen(1.25mg) plus medroxyprogesterone(5mg) for 8 weeks. Cognitive performance was measured by the Verbal Memory Test, Visual Memory Test, Trail Making Test, Digit Symbol Test, and Attention Shift Test. The Beck Depression Inventory was used for evaluation of depressed mood. The reproductive hormone levels were also measured. Results:The long duration group showed the lower performance only in Trail Making Test B compared with the short duration group at baseline. After 8 weeks, the long duration group performed significantly better in the Trail Making Test B compared with the short duration group. The differences in change of depressive mood and gonadal hormone level between two groups were not significant. Conclusion:Menopausal duration before HRT may influence the effect of estrogen on cognition in some cognitive domains. This might be related with estrogen receptor hypersensitivity which induced by the longer estrogen deficiency.

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