• 제목/요약/키워드: The Sun and the Moon

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Diagnostic Accuracy of Clinical Test for Anterior Cruciate Ligament Injury: Systematic Review

  • Deniz Yasemin;Sang-Woo Pyun;HyungSu Lee;Seong-Eun Kim;SunGyu Han;Dongyeop Lee;Ji-Heon Hong;Jae-Ho Yu;Jin-Seop Kim;Seong-gil Kim
    • The Journal of Korean Physical Therapy
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    • 제35권3호
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    • pp.57-63
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    • 2023
  • Purpose: The aim of this study was to conduct a systematic review of randomized controlled studies from 2012 to present that explore the diagnostic accuracy of clinical tests used for diagnosing anterior cruciate ligament (ACL) injury. Methods: Study design: Systematic review. Literature search of the PubMed and Scholar databases was conducted using keywords related to diagnostic accuracy of clinical tests for ACL injury. The PRISMA Guidelines were followed to conduct this study. The Cochrane Risk of Bias Tool was utilized to assess the quality of each included study. Results: As a result, 8 studies were included, and 6 clinical tests used in ACL tears were evaluated for diagnostic accuracy. The pivot shift test was reported as having the highest +LR (29.5) value with a sensitivity of 59% and a specificity of 98%. However, the test with the lowest -LR value was the lever test, and the values were as follows: -LR (0.08), +LR (4.7), specificity (80%), sensitivity (94%). Conclusion: In this study, it was concluded that a single clinical test is not sufficient to determine the presence of ACL injury. Test combinations have a higher diagnostic accuracy than a single test. In this study, the accuracy of the clinical tests was examined without considering the amount of ACL rupture and acute-chronic condition. Further research is required to examine the impact of these two factors on diagnostic accuracy of clinical test.

GUI기반의 통합 프로토타이핑 시스템 환경 개발 (An Integrated Prototyping System Environment based on The GUI)

  • 김대응;이정배;임기욱;황영섭;남지은;안성순;탁영진;엄태정
    • 한국정보처리학회:학술대회논문집
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    • 한국정보처리학회 2009년도 춘계학술발표대회
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    • pp.703-705
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    • 2009
  • 기존 통합 프로토타이핑 시스템은 가상과 실물 프로토타이핑간의 단순 연결을 통하여 시뮬레이션만 하는 것이 한계였다. 본 논문에서는 그러한 통합 프로토타이핑 기술을 개량하여 GUI기반의 가상 프로토타이핑 개발도구에 컴포넌트형태로 넣어서 드래그엔드랍을 통한 통합 프로토타이핑 시스템 환경을 구축하는 것에 대해서 보이고 있다.

Angucyclines Sch 47554 and Sch 47555 from Streptomyces sp. SCC-2136: Cloning, Sequencing, and Characterization

  • Basnet, Devi Bahadur;Oh, Tae-Jin;Vu, Thi Thu Hang;Sthapit, Basundhara;Liou, Kwangkyoung;Lee, Hei Chan;Yoo, Jin-Cheol;Sohng, Jae Kyung
    • Molecules and Cells
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    • 제22권2호
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    • pp.154-162
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    • 2006
  • The entire gene cluster involved in the biosynthesis of angucyclines Sch 47554 and Sch 47555 was cloned, sequenced, and characterized. Analysis of the nucleotide sequence of genomic DNA spanning 77.5-kb revealed a total of 55 open reading frames, and the deduced products exhibited strong sequence similarities to type II polyketide synthases, deoxysugar biosynthetic enzymes, and a variety of accessory enzymes. The involvement of this gene cluster in the pathway of Sch 47554 and Sch 47555 was confirmed by genetic inactivation of the aromatase, including a portion of the ketoreductase, which was disrupted by inserting the thiostrepton gene.

Immediate Effects of Asymmetric Chewing on Temporomandibular Joint Kinematics

  • Tae-Joon Um;Han-Seung Choi;Dong Yeop Lee;Jae Ho Yu;Jin Seop Kim;Seung Gil Kim;Jiheon Hong
    • The Journal of Korean Physical Therapy
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    • 제35권6호
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    • pp.185-189
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    • 2023
  • Purpose: This study investigated the immediate biomechanical effects of unilateral mastication for 10 minutes on the temporomandibular joint (TMJ) with 21 healthy adult participants. Methods: The gum group chewed gum on the right side for 10 minutes, and the control group rested for 10 minutes. Biomechanical data were obtained using a three-dimensional infrared camera before and after intervention. An independent t-test assessed the variation of kinematic data to identify differences between before and after intervention. Results: Among biomechanical variables, the gum group's length of the left forehead middle region and the temporomandibular joint angle decreased compared to the control group (p<0.05). Conclusion: Caution with unilateral masticatory activity is recommended, as unilateral mastication causes biomechanical changes due to excessive load on the soft tissues of the contralateral TMJ.

Altering UDP-Glucose Donor Substrate Specificity of Bacillus licheniformis Glycosyltransferase towards TDP-Glucose

  • Cho, Kye Woon;Kim, Tae-Su;Le, Tuoi Thi;Nguyen, Hue Thi;Oh, So Yeong;Pandey, Ramesh Prasad;Sohng, Jae Kyung
    • Journal of Microbiology and Biotechnology
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    • 제29권2호
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    • pp.268-273
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    • 2019
  • The specificity of a Bacillus licheniformis uridine diphosphate (UDP) glycosyltransferase, YjiC, was increased towards thymidine diphosphate (TDP)-sugar by site-directed mutagenesis. The Arg-282 of YjiC was identified and investigated by substituting with Trp. Conversion rate and kinetic parameters were compared between YjiC and its variants with several acceptor substrates such as 7-hydroxyflavone (7-HF), 4',7-dihydroxyisoflavone, 7,8-dihydroxyflavone and curcumin. Molecular docking of TDP-glucose and 7-HF with YjiC model showed pi-alkyl interaction with Arg-282 and His-14, and pi-pi interaction with $His^{14}$ and thymine ring. YjiC (H14A) variant lost its glucosylation activity with TDP-glucose validating significance of His-14 in binding of TDP-sugars.