• IMMUNE NETWORK
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• 제20권6호
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• pp.51.1-51.17
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• 2020

Respiratory syncytial virus (RSV) causes severe pulmonary disease in infants, young children, and the elderly. Formalin inactivated RSV (FI-RSV) vaccine trials failed due to vaccine enhanced respiratory disease, but the underlying immune mechanisms remain not fully understood. In this study, we have used wild type C57BL/6 and CD4 knockout (CD4KO) mouse models to better understand the roles of the CD4 T cells and cellular mechanisms responsible for enhanced respiratory disease after FI-RSV vaccination and RSV infection. Less eosinophil infiltration and lower pro-inflammatory cytokine production were observed in FI-RSV vaccinated CD4KO mice after RSV infection compared to FI-RSV vaccinated C57BL/6 mice. NK cells and cytokine-producing CD8 T cells were recruited at high levels in the airways of CD4KO mice, correlating with reduced respiratory disease. Depletion studies provided evidence that virus control was primarily mediated by NK cells whereas CD8 T cells contributed to IFN-γ production and less eosinophilic lung inflammation. This study demonstrated the differential roles of effector CD4 and CD8 T cells as well as NK cells, in networking with other inflammatory infiltrates in RSV disease in immune competent and CD4-deficient condition.

• 한국GIS학회:학술대회논문집
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• 한국GIS학회 2009년도 춘계학술대회
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• pp.138-141
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• 2009

This paper introduces AmericaView, a consortium for promoting remote sensing education, research and applications. As a case study, GeorgiaView is described in more detail. The AmericaView Consortium and StateView Consortia are good examples of collaboration for broadening the horizon of remote sensing applications in South Korea. Furthermore, the AmericaView example represents an opportunity for building a stepping stone to international collaboration.

• 한국동물학회:학술대회논문집
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• 한국동물학회 1997년도 한국생물과학협회 학술발표대회
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• pp.75-75
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• 1997

No Abstract, See Full Text

• Journal of Information Processing Systems
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• 제12권1호
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• pp.1-34
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• 2016

Gene identification is at the center of genomic studies. Although the first phase of the Encyclopedia of DNA Elements (ENCODE) project has been claimed to be complete, the annotation of the functional elements is far from being so. Computational methods in gene identification continue to play important roles in this area and other relevant issues. So far, a lot of work has been performed on this area, and a plethora of computational methods and avenues have been developed. Many review papers have summarized these methods and other related work. However, most of them focus on the methodologies from a particular aspect or perspective. Different from these existing bodies of research, this paper aims to comprehensively summarize the mainstream computational methods in gene identification and tries to provide a short but concise technical reference for future studies. Moreover, this review sheds light on the emerging trends and cutting-edge techniques that are believed to be capable of leading the research on this field in the future.

• 한국지능시스템학회:학술대회논문집
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• 한국퍼지및지능시스템학회 1993년도 Fifth International Fuzzy Systems Association World Congress 93
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• pp.1350-1353
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• 1993

A fuzzy control system typically requires“tuning,”or adjuctment of the parameters defining its linguistic variables. Automating this process amounts to applying a second“metacontrol”layer to drive the controller and plant to desired performance levels. Current methods of automated tuning rely on a single crisp numeric functional to evaluate control system performance. A generalization of Box's complex algorithm allows more realistic tuning based on lexicographic aggregation of multiple ordinal scales of performance, such as effectiveness and efficiency. The method is presented and illustrated using a simple inverted pendulum control system.

• 한국주거학회:학술대회논문집
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• 한국주거학회 1998년도 International Housing Conference
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• pp.35-39
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• 1998

• 한국학교수학회논문집
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• 제11권4호
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• pp.629-654
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• 2008

최근 들어 새롭게 개정된 미국 조지아주 수학과 교육과정을 소개하고, 이의 이해를 보다 심도 있게 도모하기 위하여 우리나라 제7차 수학과 교육과정 수정안과 비교 분석하고자 하였다. 그러나, 미국 조지아주 수학과 교육과정 전체를 한 번에 다루기에는 그 양이 너무나 방대하여, 본 고에서는 '수와 연산' 및 '대수' 영역(우리나라의 '수와 연산', '문자와 식', '규칙성' 또는 '함수'에 해당)을 중심으로 다루고자 하였다. 본고에서는 두 나라간의 교육과정 내용의 양질에 관한 우위를 가리거나 우리나라 교육과정의 문제점 내지 개선책을 마련하기 보다는 수학 교육 관련 전문가인 독자들로 하여금 대수 영역 관련의 내용에 관하여 두 나라 간에 어떠한 차이가 있는지 살펴보고 음미해 볼 수 있는 근간을 제공하고자 하였다. 또한, 본 고에 제시된 연구 결과를 비롯하여 향후 여러 나라의 수학과 교육과정을 보다 심도 있게 연구하고, 앞으로 우리나라 수학과 교육과정을 개정하는 데에 기초 자료로 활용되기를 기대한다.

• 대한수학회지
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• 제36권3호
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• pp.469-487
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• 1999

Sign patterns of idempotent matrices, especially symmetric idempotent matrices, are investigated. A number of fundamental results are given and various constructions are presented. The sign patterns of symmetric idempotent matrices through order 5 are determined. Some open questions are also given.

• 대한수의사회지
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• 제33권2호
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• pp.71-76
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• 1997

• Journal of Contemporary Eastern Asia
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• 제14권2호
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• pp.1-4
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• 2015