• Educational Technology International
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• 제24권2호
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• pp.143-168
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• 2023

This study aims to analyze the perceptions and educational needs of pre-service teachers for the use of Artificial Intelligence (AI) in education. To this end, we collected survey data from 25 undergraduate students who were enrolled in a teacher education college in Seoul. The purpose of the survey was to measure the importance and current performance for instructional AI use based on the technological, pedagogical, and content knowledge (TPACK) framework, and to explore the priority of educational needs using Borich's needs analysis and the Locus for Focus model. The results of the study confirmed that Ethics and TPK competencies are prioritized. Additionally, the results indicated a high demand for practical knowledge that can be implemented in the practice of education. Based on the results, it is necessary to develop a teacher education program that focuses on ethical aspects and teaching strategy competencies in AI-based education.

• 한국수학교육학회지시리즈B:순수및응용수학
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• 제19권4호
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• pp.315-325
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• 2012

Let A and B denote a point, a line or a circle, respectively. For a positive constant $a$, we examine the locus $C_{AB}$($a$) of points P whose distances from A and B are, respectively, in a constant ratio $a$. As a result, we establish some equivalent conditions for conic sections. As a byproduct, we give an easy way to plot points of conic sections exactly by a compass and a straightedge.

• 대한안전경영과학회:학술대회논문집
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• 대한안전경영과학회 2003년도 추계학술대회
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• pp.105-111
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• 2003

This paper examines to focus on General Strategy of e-logistics activity for SCM(Supply Chain Management) Build-up, especially the field service logistics Integration. And this research analyzes the case study (Business of Strategy Group Unit) Survey) involving effective logistics management that leads customer satisfaction, seeking to find out the key elements of competitive policy. Because problems arise from the differences between their goals and structures, which cause each sied to feel vulneralbe to opportunism or shirking of responsibilities by the other. The goal of a logistics system is to ensure that every family planning client always receives the contraceptives partner wants, and that they are in good condition and have not expired. In order to select, procure, and distribute the right Quantities of the right contraceptives, managers of the logistics system must keep informed of the rates of use of each contraceptive and of the Quantity of available supplies. As a result, We propose that a firm's e-logistics strategy is an important locus innovation and a crucial source of value creation for the firm its suppliers, partners, and customers.

• 대한안전경영과학회지
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• 제5권4호
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• pp.117-130
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• 2003

This paper examines to focus on General Strategy of e-logistics activity for SCM(Supply Chain Management) Build-up, especially the field service logistics Integration. And this research analyzes the case study(Business of Strategy Group Unit) Survey) involving effective logistics management that leads customer satisfaction, seeking to find out the key elements of competitive policy. Because problems arise from the differences between their goals and structures, which cause each sied to feel vulneralbe to opportunism or shirking of responsibilities by the other. The goal of a logistics system is to ensure that every family planning client always receives the contraceptives partner wants, and that they are in good condition and have not expired. In order to select, procure, and distribute the right quantities of the right contraceptives, managers of the logistics system must keep informed of the rates of use of each contraceptive and of the quantity of available supplies. As a result, We propose that a firm's e-logistics strategy is an important locus innovation and a crucial source of value creation for the firm its suppliers, partners, and customers.

• 미생물과산업
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• 제16권1호
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• pp.7-17
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• 1990

In summary, the nature of the amino acid changes that impart oncogenicity in either the focus formation or tumorigenicity assay can be inferred by analysis of PCR-amplified DNA from tumor-derived NIH3T3 transformants and confirmed by analysis of primary liver tumors. Putative activating mutations in the c-K-ras genetic locus have been shown to involve a single-base modification of either G-C base pair at codon 12 leading to aspartate or cystein substitutions for glycine. The oncogenicity of an N-ras oncogene containing the N-ras C gene region may be related to an amino acid substitution of valine for glycine at codon 13.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.2031-2037
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• 2012

Background: Analysis of gene-gene and gene-environment interactions for complex multifactorial human disease faces challenges regarding statistical methodology. One major difficulty is partly due to the limitations of parametric-statistical methods for detection of gene effects that are dependent solely or partially on interactions with other genes or environmental exposures. Based on our previous case-control study in Chongqing of China, we have found increased risk of colorectal cancer exists in individuals carrying a novel homozygous TT at locus rs1329149 and known homozygous AA at locus rs671. Methods: In this study, we proposed statistical method-crossover analysis in combination with logistic regression model, to further analyze our data and focus on assessing gene-environmental interactions for colorectal cancer. Results: The results of the crossover analysis showed that there are possible multiplicative interactions between loci rs671 and rs1329149 with alcohol consumption. Multifactorial logistic regression analysis also validated that loci rs671 and rs1329149 both exhibited a multiplicative interaction with alcohol consumption. Moreover, we also found additive interactions between any pair of two factors (among the four risk factors: gene loci rs671, rs1329149, age and alcohol consumption) through the crossover analysis, which was not evident on logistic regression. Conclusions: In conclusion, the method based on crossover analysis-logistic regression is successful in assessing additive and multiplicative gene-environment interactions, and in revealing synergistic effects of gene loci rs671 and rs1329149 with alcohol consumption in the pathogenesis and development of colorectal cancer.

• 전자통신동향분석
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• 제39권3호
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• pp.13-24
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• 2024

The capabilities of the metaverse have been demonstrated by representative examples such as Roblox, Fortnite, and Zepeto, and it can enable gaming, social networking services, and other applications. Nevertheless, research on the metaverse has been fragmented owing to conflicting definitions, core values, and characteristics. This ambiguity in metaverse conventions has hindered related research, analysis, and policy establishment. As the confusion seems to aggravate, consistent concepts should be established. Although the coronavirus disease pandemic led to a collapse in metaverse usage, it is regaining public interest since 2022. To promote the metaverse development, we structure core values based on existing research and surveys of consumer expectations. We found that consumers perceive the metaverse as a realistic virtual space and a potential economic opportunity. Hence, it seems necessary to track the extent to which the metaverse core values satisfy consumer demands. Such core values should be consistently reflected in policies and technology development.

• BMB Reports
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• 제49권11호
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• pp.598-606
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• 2016

ARF is an alternative reading frame product of the INK4a/ARF locus, inactivated in numerous human cancers. ARF is a key regulator of cellular senescence, an irreversible cell growth arrest that suppresses tumor cell growth. It functions by sequestering MDM2 (a p53 E3 ligase) in the nucleolus, thus activating p53. Besides MDM2, ARF has numerous other interacting partners that induce either cellular senescence or apoptosis in a p53-independent manner. This further complicates the dynamics of the ARF network. Expression of ARF is frequently disrupted in human cancers, mainly due to epigenetic and transcriptional regulation. Vigorous studies on various transcription factors that either positively or negatively regulate ARF transcription have been carried out. However, recent focus on posttranslational modifications, particularly ubiquitination, indicates wider dynamic controls of ARF than previously known. In this review, we discuss the role and dynamic regulation of ARF in senescence and cancer.

• 직업교육연구
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• 제37권5호
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• pp.55-78
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• 2018

이 연구는 도래하고 있는 4차 산업혁명 시대를 대비해 요구되는 중등 진로전담교사의 효과적인 진로지도 역량 강화를 위해 요구되는 전문성에 대한 인식과 교육요구는 어떠한지를 탐색하고 구체적인 필요 교육내용을 추출해 기초자료로 제공하기 위함이었다. 이러한 연구목적에 따라 선행연구들을 통해, 중등 진로전담교사들에게 요구되는 요구역할(8개), 요구역량(20개), 그리고 요구역량별 전문성 강화를 위한 교육내용(23개)을 도출하였고, 이를 기반으로 설문지를 구성하여, 217명으로부터 유효응답을 회수하여 분석하였으며, 그 결과는 다음과 같다. 첫째, 각 역할별, 교육내용 항목별 현재수준과 중요수준 간의 통계적 유의미한 평균 간 차이를 확인하는 t검정을 실시한 결과, 역할별에서는 '행정운영자' 역할을 제외한 전 역할에서, 세부 교육내용에서는 전 항목에서 t 값이 통계적으로 유의미하고 높은 t 값 분포를 확인하였다. 둘째, Borich 요구도 산출공식을 활용한 요구도 값 산출 및 우선순위를 파악한 결과, 전체적으로 t 값과 Borich 요구도 간에는 방향성은 일치하였다. 셋째, The Locus for Focus 모델을 활용한 우선순위 도출 결과, 전체 5개(중학교 7개, 고등학교 2개)의 교육내용이 우선순위로 도출되었다. 넷째, 차순위로 중학교 3개, 고등학교 5개를 도출하여 포함하였다. 끝으로 교육내용들과 실제적 교육 필요성과의 관련성은 어떠한지 확인하였다. 그리고 이 연구는 기존 4차 산업혁명 관련 주제와 진로지도 관련 주제의 분절 현상으로 인해 선행자료가 거의 없어 여러 한계와 제한점이 있음에도 불구하고, 향후 중등 진로전담교사의 시대 요구 적응을 위한 교육연수 프로그램 개발 및 다양한 후속 연구의 기초자료로 활용될 수 있기를 기대하며 몇 가지 제언을 하고 있다.

• 한국가정과교육학회지
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• 제35권2호
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• pp.41-59
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• 2023

본 연구는 가정과 교사의 푸드리터러시 함양을 위한 식생활교육 요구도 분석하여 푸드리터러시 함양을 위한 중등 가정과 식생활교육의 발전 방향을 제시하는 것을 목적으로 하였다. 연구 목적을 달성하기 위해 192명의 가정과 교사를 대상으로 푸드리터러시 교육의 내용 영역과 내용 요소에 대한 중요도와 현재 실행도에 대한 인식을 조사하고, 교육 요구도 조사 결과를 기반으로 푸드리터러시 교육을 위한 내용 영역과 내용 요소의 우선순위를 파악하였다. 가정과 교사는 제시된 38개 내용 요소 중 34개 내용 요소에 대하여 중요도에 비하여 현재 실행도를 유의적으로 낮게 인식하고 있었다. Borich의 교육 요구도 공식과 The Locus for Focus Model을 활용하여 교육 요구도가 '매우 높은' 5가지 내용 요소('식량 주권/식량 안보', '식품 관련 쓰레기 저감화', '음식물쓰레기 처리와 재활용', '식품 관련 쓰레기와 분리수거', '원산지 정보')를 도출하였으며, 다음으로 요구도가 '높은' 4가지 내용 요소('유전자 변형 식품', '윤리적 소비', '식품 첨가물', '친환경 농산물')를 확인하였다. 요구도가 매우 높은 것으로 나타난 내용 요소는 '생산' 영역과 '폐기' 영역에 해당하는 것으로 나타나 '생산'과 '폐기' 영역에 대한 교육 요구도 역시 높음을 알 수 있었다. 따라서 향후 가정과 푸드리터러시 함양을 위한 식생활교육을 위해 식품의 생산과 폐기를 강조하여 다루는 것이 필요하며, 이 외에도 푸드리터러시 함양을 위한 가정과 식생활교육의 세부 내용 및 콘텐츠 개발을 위한 연구가 필요하다. 본 연구의 결과는 영양 및 식품에 대한 지식 습득과 개인 차원의 식품 소비 단계를 중심으로 구성된 기존의 식생활교육의 패러다임에서 벗어나 학생들이 식품의 생산에서부터 폐기까지의 전 과정을 학습할 수 있는 새로운 가정과 식생활교육의 필요성에 대한 시사점을 제안할 수 있다. 또한 중등 가정과 푸드리터러시 함양을 위한 식생활교육의 기초 연구로 활용되기를 기대한다.