• Genomics & Informatics
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• v.8 no.1
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• pp.1-8
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• 2010

Serpin peptidase inhibitor, Clade B (ovalbumin), Member 5 (SERPINB5), also known as maspin, is a potent tumor suppressor gene. It has correlations with many tumor cells, from pancreas cancer to breast cancer, so it is possible that it may also affect liver cancer. There has also been a report that SERPINB12, a gene placed right next to SERPINB5, is expressed in liver. For this study, 32 polymorphisms were identified in SERPINB5 by direct DNA sequencing, and 11 of them were selected to be tested with a larger scale subjects. The association of the 11 SERPINB5 polymorphisms with Hepatitis B virus (HBV) clearance, hepatocellular carcinoma (HCC) occurrence and the onset age of HCC were analyzed. There were no significant associations found between 11 SERPINB5 polymorphisms and HBV clearance. In the case of HCC occurrence, one of the haplotypes (ht) showed association with HCC occurrence (OR=2.26, p=0.005, $P^{Cor}=0.05$), albeit with a low statistical power (40.8%) and haplotype frequency (0.052). Further study with a bigger sample size will be needed to clearly verify the association between ht5 and HCC occurrence.

• Wind and Structures
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• v.7 no.4
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• pp.265-280
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• 2004

This paper presents some fundamental results on the dynamics of the periodic Karman wake behind a circular cylinder. The wake is treated like a dynamical system. External forcing is then introduced and its effect investigated. The main result obtained is the following. Perturbation of the wake, by controlled cylinder oscillations in the flow direction at a frequency equal to the Karman vortex shedding frequency, leads to instability of the Karman vortex structure. The resulting wake structure oscillates at half the original Karman vortex shedding frequency. For higher frequency excitation the primary pattern involves symmetry breaking of the initially shed symmetric vortex pairs. The Karman shedding phenomenon can be modeled by a nonlinear oscillator. The symmetrical flow perturbations resulting from the periodic cylinder excitation can also be similarly represented by a nonlinear oscillator. The oscillators represent two flow modes. By considering these two nonlinear oscillators, one having inline shedding symmetry and the other having the Karman wake spatio-temporal symmetry, the possible symmetries of subsequent flow perturbations resulting from the modal interaction are determined. A theoretical analysis based on symmetry (group) theory is presented. The analysis confirms the occurrence of a period-doubling instability, which is responsible for the frequency halving phenomenon observed in the experiments. Finally it is remarked that the present findings have important implications for vortex shedding control. Perturbations in the inflow direction introduce 'control' of the Karman wake by inducing a bifurcation which forces the transfer of energy to a lower frequency which is far from the original Karman frequency.

• Journal of Industrial Convergence
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• v.21 no.1
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• pp.187-192
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• 2023

In this study, trends in ICT education were investigated by analyzing the frequency of appearance of keywords related to machine learning and using conversion of iteration correction(CONCOR) techniques. A total of 304 papers from 2018 to the present published in registered sites were searched on Google Scalar using "ICT education" as the keyword, and 60 papers pertaining to ICT education were selected based on a systematic literature review. Subsequently, keywords were extracted based on the title and summary of the paper. For word frequency and indicator data, 49 keywords with high appearance frequency were extracted by analyzing frequency, via the term frequency-inverse document frequency technique in natural language processing, and words with simultaneous appearance frequency. The relationship degree was verified by analyzing the connection structure and centrality of the connection degree between words, and a cluster composed of words with similarity was derived via CONCOR analysis. First, "education," "research," "result," "utilization," and "analysis" were analyzed as main keywords. Second, by analyzing an N-GRAM network graph with "education" as the keyword, "curriculum" and "utilization" were shown to exhibit the highest correlation level. Third, by conducting a cluster analysis with "education" as the keyword, five groups were formed: "curriculum," "programming," "student," "improvement," and "information." These results indicate that practical research necessary for ICT education can be conducted by analyzing ICT education trends and identifying trends.

• Journal of the Korean Society of Safety
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• v.31 no.3
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• pp.47-52
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• 2016

This paper describes the design and fabrication of high frequency ground impedance measuring system for assessment of grounding system for Lightning protection. The ground impedance measuring system has been designed and fabricated which makes it possible to assess the ground impedance by frequency ranges from 100 Hz to 1 MHz. The effective grounding systems having a very low impedance to electromagnetic disturbance such as lightning surges and noises in microelectronics and high-technology branches are strongly required. In order to analyze the dynamic characteristic of grounding system impedances in lightning and surge protection grounding systems, it is highly desirable to assess the ground impedances as a measure of performance of grounding system in which lightning and switching surge currents with fast rise time and high frequency flow. The measuring system is based on the variable frequency power supply and consists of signal circuit part, main control part, data acquisition and processing unit, and voltage and current probe system. The ground impedance measuring system can be used to assess grounding system during occurrence of lightning.

• The Journal of Engineering Geology
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• v.16 no.2 s.48
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• pp.201-214
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• 2006

To study the relationship between rainfall conditions and landslides according to a geological condition in land-slides areas such asJangheung Kyounggi, Sangju and Pohang Kyoungbuk, the data of rainfall and landslides are investigated and analyzed. Many landslides occurred at these areas because of the heavy rainfall in two or four days of the summer 1998. The data of rainfall are collected in observatories within a 50km radius from landslides occurrence areas, and the data of landslides are investigated directly in landslides areas. The data of rainfall are the accumulative rainfall and the rainfall intensity, and the data of landslides are the occurrence frequency considering the geological condition. These data are analyzed statistically to know the relationship the rainfall and landslides. The landslides are concentrated in the heavy rainfall area from the analysis of these data. It knows that the land-slides are triggered by the heavy rainfall. Meanwhile, the rainfall factors such as the accumulative rainfall, the rain-fall intensity and the dropping time are different in each landslides area, and the shape and frequency of landslides are different respectively. The landslides have occurred in the area of high accumulative rainfall, while the land-slides have not occurred around that area. Therefore, the rainfall is very important factor induced by the landslides, and the accumulative rainfall is really related to the frequency of landslides.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.20 no.8
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• pp.25-32
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• 2021

Washboarding is a crucial problem occurring on unpaved roads. This phenomenon involves the formation of ripples on the surface of the unpaved road and causes a critical problem to vehicles and riders. The phenomenon is affected by several parameters, but we focused on the velocity and the size of the rotating body. In the precedent research, we observed that a critical velocity existed for the occurrence of the phenomenon, and the phenomenon's grade was related to the velocity. Therefore, this study, using a discrete element method, aimed to analyze the relation between the velocity and the size of the rotating body for the occurrence of the phenomenon and perform a fast Fourier transform (FFT) analysis to determine the correlation between the phenomenon and the period. The study observed that the critical velocity could vary from the velocity and the size of the rotating body, and there was a certain range of frequency for the occurrence of the Washboarding phenomenon.

• Research in Community and Public Health Nursing
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• v.29 no.4
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• pp.429-439
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• 2018

Purpose: The aim of this study is to identify core keyword of frailty research in the past 35 years to understand the structure of knowledge of frailty. Methods: 10,367 frailty articles published between 1981 and April 2016 were retrieved from Web of Science. Keywords from these articles were extracted using Bibexcel and social network analysis was conducted with the occurrence network using NetMiner program. Results: The top five keywords with a high frequency of occurrence include 'disability', 'nursing home', 'sarcopenia', 'exercise', and 'dementia'. Keywords were classified by subheadings of MeSH and the majority of them were included under the healthcare and physical dimensions. The degree centralities of the keywords were arranged in the order of 'long term care' (0.55), 'gait' (0.42), 'physical activity' (0.42), 'quality of life' (0.42), and 'physical performance' (0.38). The betweenness centralities of the keywords were listed in the order of depression' (0.32), 'quality of life' (0.28), 'home care' (0.28), 'geriatric assessment' (0.28), and 'fall' (0.27). The cluster analysis shows that the frailty research field is divided into seven clusters: aging, sarcopenia, inflammation, mortality, frailty index, older people, and physical activity. Conclusion: After reviewing previous research in the 35 years, it has been found that only physical frailty and frailty related to medicine have been emphasized. Further research in psychological, cognitive, social, and environmental frailty is needed to understand frailty in a multifaceted and integrative manner.

• Journal of the Korean earth science society
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• v.23 no.8
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• pp.683-696
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• 2002

In this work. we investigated the ozone data sets that exceeded ambient air quality standards from 31 air quality monitoring stations dispersed across the Seoul metropolitan city during the period covering 1990 and 2000. To specifically describe spatial dependency of high level O$_3$ occurrence, we grouped our data into four different geographical ozone exceedance is much longer in SW than the other three sectors. When we compared the exceedance data in terms of occurrence frequency, the month of maximum frequency differed slightly among different sectors. Examination of long-term exceedance trend indicated that its frequency increased continuously from all sectors over the past years, although slightly opposite patterns existed in their absolute values. Most importantly, its peak occurrence frequency seemed to center in very recent years such as 1998 (NE sector) and 2000 (ail pattern sectors except NE). Consequently, we were able to describe the existence of certain patterns of ozone exceedance data sets in terms of both temporal and spatial scales.

• Journal of the Korea Institute of Building Construction
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• v.9 no.2
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• pp.93-101
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• 2009

Recently, public interest in housing defects, such as construction errors, occupiers' complaints, faults in production, and so on, is increasing. In addition, the construction requirements of high-rise residential buildings have increased, due to the higher prices of urban areas, especially in metropolitan areas. While previous research has focused on the defects occurring in apartment housing complexes, research has not been carried out on the defects occurring in high-rise residential buildings. In this paper, the defects patterns and characteristics of high-rise residential buildings are examined and analyzed and a defect management plan is then suggested. In order to do this, we collected the defects data of high-rise residential buildings recorded by 2,299 of 2,327 occupants. The defect occurrence rate (DOR) in the residential area is 98.8%. The frequency rate of defect occurrence over the total defect occurrence since building completion is 63.28% during the first year, 24.63% (second year), 6.88% (third year), 2.27% (fourth year), and 2.53% (fifth year). The result of correlation analysis between work types showed that there is a relationship between the built-in furniture and electronics (F&E) and painting works, and the F&E and masonry works, such as marble finishing. We expect that this research will assist in the efforts to decrease the number of defects in high-rise buildings.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.14 no.5
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• pp.472-485
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• 1989

This paper represents the occurrence structure of the timing variation of TV horizontal synchronizing pulse(H-sync pulse) in mobile TV reception. Fluttering ghost is caused by timing varations of the H-sync pulse and is due to frequency elective fading in a multipath propagation envoronment. H-sync timing fluctuations, and hence, fluttering ghost are directly correlated with the multipath parameters, i.e., H-sync timing fluctuations reflect well the severity of the multipath environment. The occurrence structure of H-sync timtng fluctuation is analysed theoretically in relation to the multipath environnment. The occurrence structure of H-sync timing fluctuation is analysed theoretically in relation to the multipath parameters, assuming the two-ray propagation model. The H-sync timing fluctuation occurs with the variation in relative phase and /or D/U variation of long-delayed multipath waves.