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Effect of Nokyongdaebo-tang on chronic anemia in Taeumin wiwansuhan-pyohan disease (胃脘受寒表寒病) patient: a case report

  • Ha, Su-Jeong;Jung, Hee Tae;Song, Si Yeon;Ko, Myung-Hyun;Park, Ji-Hye;Yoo, Hwa-Seung;Park, So-Jung
    • The Journal of Korean Medicine
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    • v.41 no.4
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    • pp.112-119
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    • 2020
  • Objectives: The present study reports a case of chronic anemia patient who was significantly improved after taking Nokyongdaebo-tang (NYDBT) Methods: A 48-year-old male patient diagnosed with iron deficiency anemia (IDA) visited the Daejeon Korean medicine Hospital of Daejeon University on June 2018. The patient was treated with Korean medicine for 23 months including acupuncture, herbal medicine and Sasang constitutional medicine prescription. Improvement of anemia was assessed by changes of Hemoglobin value. Laboratory analysis was used to evaluate the safety of treatment. Results: Chronic anemia has significantly improved since taking NYDBT on 9 days (2019.12.09-2019.12.17). The Hb value has been maintained in the normal range since it first entered the normal range on January 18, 2020. The patient had become transfusion-free and this condition persisted for 6 months after stopping the transfusion. Conclusion: This case demonstrates the therapeutic potential of Sasang constitutional medicine for chronic anemia as a personalized medicine.

Microclimate, Growth and Yield in Wheat under North-South and East-West Row Orientation (이랑방향에 따른 밀 군락의 미기상과 생육 및 수량)

  • Yoon, Seong-Tak;Jerry, Johnson
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.49 no.3
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    • pp.155-159
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    • 2004
  • This experiment was carried out to evaluate the microclimate of wheat canopy, growth and yield characteristics of wheat under north-south and east-west row orientation. The variety used in this experiment was "AG South 2000", which was developed in USA. Solar radiation, air temperature, relative humidity, and soil temperature were monitored by data logger from March to May in 2002, The ratio of light penetration to the bottom from the upper canopy was 36.8% in north-south and 21.4% in east-west row orientation. Temporal march of light penetration to the bottom from March to May decreased as wheat developed canopy structure and decreased a little from May as plant were matured. The highest light penetration to the bottom from upper canopy occurred at 13:00 in both north-south and east-west row orientations, respectively which were 36 times in north-south and 27 times in east-west row orientation, respectively. Daily maximum temperature at the bottom of canopy occurred at 14:00 with 29 times in north-south, while 19 times were obtained at 14:00 and 15:00, respectively in east-west row orientation. Relative humidity at the bottom of the canopy in east-west yow orientation showed higher than that of north-south row orientation. Occurrence of daily maximum soil temperature of north-south showed one hour later compared with east-west yow orientation. 1000 grain weight and test weight of north-south row orientation was higher than those of east-west vow orientation. Correlation coefficient between solar radiation of upper canopy and 1000 grain weight showed r=$0.8132^{*}$, and between air temperature of upper canopy and number of spikes per $\textrm{m}^{2}$ and 1000 grain weight showed significant positive correlation with r=$0.8139^{*}$, and r=$0.8293^{*}$, respectively.

Effects of Inonotus obliquus Extracts on Immunomodulating Activity

  • Song, Kee-Cheol;Choi, Byung-Lyul;Shin, Jang-Woo;Son, Jin-Young;Yoo, Hwa-Seung;Cho, Jung-Hyo;Lee, Yeon-Weol;Son, Chang-Gue;Cho, Chong-Kwan
    • The Journal of Korean Medicine
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    • v.28 no.4
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    • pp.27-41
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    • 2007
  • Aim : This study aimed at elucidating the effects of Inonotus obliquus on anti-tumor effects in vivo and immune-based characterization of the mushroom as a potential candidate for cancer remedy. Methods : To investigate the immunomodulatory effects of Inonotus obliquus, we investigated macrophage functions and NK cell activities through the measurement of NO production of macrophage, NK cell cytotoxicity and expressions of cytokines and genes regulating immune responses, in addition to pulmonary metastasis model in vivo. Results : Inonotus obliquus showed general cytotoxicity at high concentrations over the 100 ${\mu}g/m{\ell}$ on the both of normal and cancer cell lines. Inonotus obliquus showed both inhibitory and promotive effects on pulmonary colonization of CT-26 cell depending on period or route of administration in vivo. Conclusion : From these results, it cannot be concluded that Inonotus obliquus has cancer-specific activity. Furthermore, Inonotus obliquus has the provability to show adverse effects differently according to the concentration and the method of administration.

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Analysis of Studies Related with Anti-cancerous herbs that is Uesd in Clinical Treatment Recently : Analyzing Articles from PubMed Search (항암 본초에 관한 최근의 연구 동향 분석 - Pub med 검색을 통해)

  • Yoon, Dam-Hee;Cho, Jung-Hyo;Son, Chang-Gue;Yoo, Hwa-Seung;Lee, Yeon-Weol;Lee, Nam-Heon;Lee, Jong-Hoon;Bang, Sun-Hwi;Cho, Chong-Kwan
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.6
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    • pp.1763-1768
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    • 2006
  • Cancer is one of the most serious health problem in modern society, and there are many studies to treat this disease. We have performed the study about analyzing papers related with anti-cancerous herbs that is used in clinical treatment recently. We found 257 papers in 'Pub med', the internet site, using the key words 'cancer' and the scientific name of anti-cancerous herbs. We also have compared the herbs' efficacy in oriental medicine with the experimental results in those papers, and thought the practical uses in clinical treatments. However, research studies that reported data on anti-cancerous herbs were wholly lacking. It is recommended that further studies be performed from the point of view of oriental medicine.

Nomenclature of the Seas Around the Korean Peninsula Derived From Analyses of Papers in Two Representative Korean Ocean and Fisheries Science Journals: Present Status and Future (국내 대표 해양·수산 과학논문 분석을 통한 우리나라 주변 바다 이름표기에 대한 제언)

  • BYUN, DO-SEONG;CHOI, BYOUNG-JU
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.23 no.3
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    • pp.125-151
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    • 2018
  • We grouped the names attributed to the seas surrounding the Korean Peninsula in maps published in two major Korean ocean and fisheries science journals over the period from 1998 to 2017: the Journal of the Korean Society of Oceanography (The Sea) and the Korean Journal of Fisheries and Aquatic Science (KFAS). The names attributed to these seas in maps of journal paper broadly were classified into three groupings: (1) East Sea and Yellow Sea; (2) East Sea, Yellow Sea, and South Sea; or (3) East Sea, West Sea and South Sea. The name 'East Sea' was dominantly used for the waters between Korea and Japan. In contrast, the water between Korea and China has been mostly labelled as 'Yellow Sea' but sometimes labelled as 'West Sea'. The waters between the south coast of Korea and Kyushu, Japan were labelled as either 'Korea Strait' or 'South Sea'. This analysis on sea names in the maps of 'The Sea' and 'KFAS' reveals that domestic researchers frequently mix geographical and international names when referring to the waters surrounding the Korean Peninsula. These inconsistencies provide the motivation for the development of a basic unifying guideline for naming the seas surrounding the Korean Peninsula. With respect to this, we recommend the use of separate names for the marginal seas between continental landmasses and/or islands versus for the coastal waters surrounding Korea. For the marginal seas, the internationally recognized names are recommended to be used: East Sea; Yellow Sea; Korea Strait; and East China Sea. While for coastal seas, including Korea's territorial sea, the following geographical nomenclature is suggested to differentiate them from the marginal sea names: Coastal Sea off the East Coast of Korea (or the East Korea Coastal Zone), Coastal Sea off the South Coast of Korea (or the South Coastal Zone of Korea), and Coastal Sea off the West Coast of Korea (or the West Korea Coastal Zone). Further, for small or specific study areas, the local region names, district names, the sea names and the undersea feature names can be used on the maps.

Paleoenvironmental Changes in the Northern East China Sea and the Yellow Sea During the Last 60 ka

  • Nam, Seung-Il;Chang, Jeong-Hae;Yoo, Dong-Geun
    • The Korean Journal of Quaternary Research
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    • v.17 no.2
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    • pp.165-165
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    • 2003
  • A borehole core ECSDP-102 (about 68.5 m long) has been investigated to get information on paleoenvironmental changes in response to the sea-level fluctuations during the period of late Quaternary. Several AMS $\^$14/C ages show that the core ECSDP-102 recorded the depositional environments of the northern East China Sea for approximately 60 ka. The Yangtze River discharged huge amounts of sediment into the northern East China Sea during the marine isotope stage (MIS) 3. In particular, $\delta$$\^$13/Corg values reveal that the sedimentary environments of the northern East China Sea, which is similar to the Holocene conditions, have taken place three times during the MIS 3. It is supported by the relatively enriched $\delta$$\^$13/Corg values of -23 to -21$\textperthousand$ during the marine settings of MIS 3 that are characterized by the predominance of marine organic matter akin to the Holocene. Furthermore, we investigated the three Holocene sediment cores, ECSDP-101, ECSDP-101 and YMGR-102, taken from the northern East China Sea off the mouth of the Yangtze River and from the southern Yellow Sea, respectively. Our study was focused primarily on the onset of the post-glacial marine transgression and the reconstructing of paleoenvironmental changes in the East China Sea and the Yellow Sea during the Holocene. AMS $\^$14/C ages indicate that the northern East China Sea and the southern Yellow Sea began to have been flooded at about 13.2 ka BP which is in agreement with the initial marine transgression of the central Yellow Sea (core CC-02). $\delta$$\^$18/O and $\delta$$\^$13/C records of benthic foraminifera Ammonia ketienziensis and $\delta$$\^$13/Corg values provide information on paleoenvironmental changes from brackish (estuarine) to modem marine conditions caused by globally rapid sea-level rise since the last deglaciation. Termination 1 (T1) ended at about 9.0-8.7 ka BP in the southern and central Yellow Sea, whereas T1 lasted until about 6.8 ka BP in the northern East China Sea. This time lag between the two seas indicates that the timing of the post-glacial marine transgression seems to have been primarily influenced by the bathymetry. The present marine regimes in the northern East China Sea and the whole Yellow Sea have been contemporaneously established at about 6.0 ka BP. This is strongly supported by remarkably changes in occurrence of benthic foraminiferal assemblages, $\delta$$\^$18/O and $\delta$$\^$13/C compositions of A. ketienziensis, TOC content and $\delta$$\^$13/Corg values. The $\delta$$\^$18/O values of A. ketienziensis show a distinct shift to heavier values of about 1$\textperthousand$ from the northern East China Sea through the southern to central Yellow Sea. The northward shift of $\^$18/O enrichment may reflect gradually decrease of the bottom water temperature in the northern East China Sea and the Yellow Sea.

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Maturation and spawning of the Pacific cod, Gadus macrocephalus TILESIUS in East Sea of Korea (한국 동해안 대구, Gadus macrocephalus TILESIUS의 성숙과 산란)

  • Can, Hyung-Kee;Lee, Sung-Il;Yoon, Sang-Chul;Kim, Young-Seop;Chun, Young-Yull;Chang, Dae-Soo;Yang, Jae-Hyeong
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.43 no.4
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    • pp.320-328
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    • 2007
  • Maturation and spawning of the Pacific cod, Gadus macrocephalus was investigated based on the samples captured in East Sea of Korea from April 2006 to July 2007. Gonadosomatic index began to increase in November, and reached maximum between December and January. After spawning it began to decrease from March. Reproductive season was estimated to November-February, with peak in January. Fecundity was proportional to the size of the female, with the clutch size varying from 753,985 eggs in the smallest female(TL=58.6cm) to 9,311,520 eggs in the largest(TL=101.0cm). Size at 50% sexual maturity(TL50%) determined from mature females was 56.3cm of TL. Annual reproductive cycles of this species could be divided into six successive stages; immature stage(March-September), nucleolus stage(September-October), yolk vesicle stage(October-November), vitellogenic stage (November-December), ripe stage and spent stage(December-February).

Humidity and Temperature Response Characteristics of Optical Fiber Dislocation Fusion Sensor Coated with Graphene Quantum Dots

  • Dailin Li;Xiaodan Yu;Ning Wang;Wenting Liu;Shiqi Liu;Liang Xu;Dong Fang;Huapeng Yu
    • Current Optics and Photonics
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    • v.7 no.5
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    • pp.504-510
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    • 2023
  • An optical fiber dislocation fusion humidity sensor coated with graphene quantum dots is investigated. A Mach-Zehnder interferometer is fabricated with three dislocated single-mode fibers with graphene quantum dots coating humidity-sensitive materials. Humidity response experiments showed a good linear response and high sensitivity with easy fabrication and low-cost materials. From 22% to 98% RH, the humidity response sensitivity of the sensor is 0.24 dB/% RH, with 0.9825 linearity. To investigate the cross-response of humidity and temperature, temperature response experiments are conducted. From 30 ℃ to 70 ℃, the results showed 0.02 dB/℃ sensitivity and 0.9824 linearity. The humidity response experimental curve is compared with the temperature experimental curve. The big difference between humidity sensitivity and temperature sensitivity is very helpful to solve the cross-response of humidity and temperature. The influence of temperature fluctuations in humidity measurements is not obvious.

A Study on East Asia Cultural Diversity in Geography Education: Centered on "Human Relationship and Living-Habit" Culture (동아시아 상호 이해를 위한 문화 다양성 교육의 시론적 연구 -"인간관계와 생활습관" 문화를 중심으로-)

  • Kim, Da-Won
    • Journal of the Korean Geographical Society
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    • v.46 no.1
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    • pp.100-114
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    • 2011
  • The purpose of this study is to suggest the contents for geography education about East Asian cultural diversity. I chose "Human Relationship and Living-Habit" culture among East Asian diverse cultures and fixed 4 themes: family cultures, traditional cultures, friendship cultures and relationship cultures with other people. For making the lesson contents for East Asian cultural diversity, I analysed Geography 2009 Revised Curriculum and presented specific contents differently depending on grades. Until now, static and homogeneous cultures in East Asia have been emphasized mostly at school but cultures that are dynamic and related to students$^{\circ}{\phi}$ life are proposed in this study. Through understanding the differences of the East Asian cultures, it will be possible to expand mutual understandings among the East Asian people. This study will be a good alternative and paving the way for enhancing cooperations in East Asia.