DOI QR코드

DOI QR Code

Effect of Nokyongdaebo-tang on chronic anemia in Taeumin wiwansuhan-pyohan disease (胃脘受寒表寒病) patient: a case report

  • Ha, Su-Jeong (East-West Cancer Center, Daejeon Korean Medicine Hospital of Daejeon University) ;
  • Jung, Hee Tae (East-West Cancer Center, Daejeon Korean Medicine Hospital of Daejeon University) ;
  • Song, Si Yeon (East-West Cancer Center, Daejeon Korean Medicine Hospital of Daejeon University) ;
  • Ko, Myung-Hyun (East-West Cancer Center, Daejeon Korean Medicine Hospital of Daejeon University) ;
  • Park, Ji-Hye (East-West Cancer Center, Seoul Korean Medicine Hospital of Daejeon University) ;
  • Yoo, Hwa-Seung (East-West Cancer Center, Seoul Korean Medicine Hospital of Daejeon University) ;
  • Park, So-Jung (East-West Cancer Center, Daejeon Korean Medicine Hospital of Daejeon University)
  • Received : 2020.07.29
  • Accepted : 2020.10.07
  • Published : 2020.12.01

Abstract

Objectives: The present study reports a case of chronic anemia patient who was significantly improved after taking Nokyongdaebo-tang (NYDBT) Methods: A 48-year-old male patient diagnosed with iron deficiency anemia (IDA) visited the Daejeon Korean medicine Hospital of Daejeon University on June 2018. The patient was treated with Korean medicine for 23 months including acupuncture, herbal medicine and Sasang constitutional medicine prescription. Improvement of anemia was assessed by changes of Hemoglobin value. Laboratory analysis was used to evaluate the safety of treatment. Results: Chronic anemia has significantly improved since taking NYDBT on 9 days (2019.12.09-2019.12.17). The Hb value has been maintained in the normal range since it first entered the normal range on January 18, 2020. The patient had become transfusion-free and this condition persisted for 6 months after stopping the transfusion. Conclusion: This case demonstrates the therapeutic potential of Sasang constitutional medicine for chronic anemia as a personalized medicine.

Keywords

Acknowledgement

This study was supported by Ministry of Health & Welfare, Republic of Korea (Grant Number : HI9C1046) and National Research Foundation of Korea (Grant number : 20200050).

References

  1. Shin TF. Steps to Internal Medicine 1. Seoul : Jungdam 2005:29-66.
  2. Kassebaum NJ, Jasrasaria R, Naghavi M et al. A systematic analysis of global anemia burden from 1990 to 2010. Blood 2014;123:615-624. https://doi.org/10.1182/blood-2013-06-508325
  3. Vecchio LD, Locatelli F. Clinical practice guidelines on iron therapy: A critical evaluation. Hemodialysis International 2017;21:S125-S131 https://doi.org/10.1111/hdi.12562
  4. Pasricha SR, Flecknoe-Brown SC, Allen KJ et al. Diagnosis and management of iron deficiency anaemia: a clinical update. Med J Aust. 2010;193:525-532. https://doi.org/10.5694/j.1326-5377.2010.tb04038.x
  5. Chae H, Lyoo IK, Lee SJ, Cho S, Bae H, Hong M. An alternative way to individualized medicine: psychological and physical traits of Sasang typology. J Altern Complement Med. 2003;9(4):519-528. https://doi.org/10.1089/107555303322284811
  6. Lee YH, Kim JD, Hwang HJ. A Case Study on the Iron Deficiency Anemia. Korean J. Orient. Int. Med. 2000;21(4):655-60.
  7. Kim EG, Kim SK, Shim YS, Han JH, Lee JH. A clinical report on iron deficiency anemia. Korean J. Orient. Int. Med. 2004;25(4-2):356-63.
  8. Jang EG, Kwon SY, Cho YH, Woo HJ, Kim YC, Lee JH. A case of Guibitanggami treatment to an iron deficiency anemia patient. Korean J. Orient. Int. Med. 2013;142-147.
  9. Carpenter J, Barber M, Aronson JK, et al. The CARE guidelines: Consensus-based clinical case reporting guideline development. Glob Adv Heal Med 2013;2:38-43.
  10. Platzbecker U, Hofbauer LC, Ehninger G, Holig K. (2012). The clinical, quality of life, and economic consequences of chronic anemia and transfusion support in patients with myelodysplastic syndromes. Leukemia Research, 36(5), 525-536. https://doi.org/10.1016/j.leukres.2012.01.006
  11. Choi AR, Shin MR, Lee EJ. Clinical practice guideline for Taeeumin disease of Sasang constitutional medicine: Esophagus cold-based exterior cold (Wiwansuhan-pyohan) disease. J Sasang Constitut Med. 2015;27(1):42-56. https://doi.org/10.7730/JSCM.2015.27.1.042
  12. Lee C. Uihagimmun(醫學入門). Seoul: Bubin. 2009:1900.
  13. Lee JM. Dongui-Susebowon (東醫壽世保元). 1984.
  14. Cheong MH, Jung IC, Lee SR. The neuroprotective effects of Nokyongdaebo-tang (Lurongdabutang) treatment in pathological Alzheimer's disease model of neural tissues. J Oriental Neuropsychiatry. 2009;20(2):1-17.
  15. Lee KA, Chung HY. Biological activities of a Korean traditional prescription, Nogyongdaebotang. J Korean Soc Food Sci Nutr. 2004;33(1):28-33. https://doi.org/10.3746/JKFN.2004.33.1.028
  16. Lee SW, et al. Preventive effects of Nokyongdaebotang on hyperlipidemia rats. Kor J Oriental Preventive Medical Society. 2003;7(2):107-19.
  17. Lee SY, Ahn TW. Anti-aging effect of Tae-Eumin's Nocyongdaebo-tang (NYD) in aged rats. J Sasang Constitutional Medicine. 2008;20(2):58-71.
  18. Bae NY, Ahn TW. The anti-oxidative effect of oral administration of NYD (Nocyongdaebo-tang) in oxidized rats induced by AAPH. J Sasang Constitutional Medicine. 2007;19(2):155-69.
  19. Kim JA, Kim DC. Ameliorating Effects of Nokyongdaebo-tang on Experimental Subacute Hemorrhagic Anemia in Rats. J Korean Obstet Gynecol. 2017;30:1-19. https://doi.org/10.15204/jkobgy.2017.30.1.001