• 한국미생물학회:학술대회논문집
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• 한국미생물학회 2002년도 추계학술대회
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• pp.185-193
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• 2002

We have developed GComp as an analysis tool for comparative analysis of microbial genomes. Thetool uses BLAST or FASTA as a preprocessing program for local alignments, parses the homology search results, and generates tables and files to show homology relationship between two genomes at a glance. The interface for graphical representation of the comparative genomic analysis has been also implemented. Through analysis of a few pairs of microbial genome sequences, the program has been proved to be practically useful and a few additional features have been devised and designed, which will be added in the further development.

• Wind and Structures
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• 제31권3호
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• pp.269-285
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• 2020

The statistical characteristics of typhoon wind speed records tend to have a considerable time-varying trend; thus, the stationary wind model may not be appropriate to estimate the wind characteristics of typhoon events. Several nonstationary wind speed models have been proposed by pioneers to characterize wind characteristics more accurately, but comparative studies on the applicability of the different wind models are still lacking. In this study, three landfall typhoons, Ampil, Jongdari, and Rumbia, recorded by ultrasonic anemometers atop the Shanghai World Financial Center (SWFC), are used for the comparative analysis of stationary and nonstationary wind characteristics. The time-varying mean is extracted with the discrete wavelet transform (DWT) method, and the time-varying standard deviation is calculated by the autoregressive moving average generalized autoregressive conditional heteroscedasticity (ARMA-GARCH) model. After extracting the time-varying trend, the longitudinal wind characteristics, e.g., the probability distribution, power spectral density (PSD), turbulence integral scale, turbulence intensity, gust factor, and peak factor, are comparatively analyzed based on the stationary wind speed model, time-varying mean wind speed model and time-varying standard deviation wind speed model. The comparative analysis of the different wind models emphasizes the significance of the nonstationary considerations in typhoon events. The time-varying standard deviation model can better identify the similarities among the different typhoons and appropriately describe the nonstationary wind characteristics of the typhoons.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2004년도 ICEIC The International Conference on Electronics Informations and Communications
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• pp.269-273
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• 2004

This paper presents a comparative performance analysis of a network accelerator model based on M/M/l queuing system. It assumes the Poisson distribution as its input traffic load. The decoding delay is employed as a performance analysis measure. Simulation results based on the proposed model show only $15\%$ differences with respect to actual measurements on field traffic for BCM5820 accelerator device. The performance analysis model provides with reasonable hardware structure of network servers, and can be used to span design spaces statistically.

• 통합자연과학논문집
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• 제9권1호
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• pp.1-9
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• 2016

Leucine rich repeat kinase 2 (LRRK2) is a highly promising target for Parkinson's disease (PD) that affects millions of people worldwide. A three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis was performed on a series of pyrrolopyrimidine-based selective LRRK2 kinase inhibitors. This study was performed to rationalize the structural requirements responsible for the inhibitory activity of these compounds. A reliable 3D-QSAR model was developed using comparative molecular field analysis (CoMFA) technique. The model produced statistically acceptable results with a cross-validated correlation coefficient ($q^2$) of 0.539 and a non-cross-validated correlation coefficient ($r^2$) of 0.871. Robustness of the model was further evaluated by bootstrapping and progressive scrambling analysis. This work could assist in designing more potent LRRK2 inhibitors.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.65.2-65.2
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• 2003

88 selective COX-2 inhibitors belonging to three chemical classes (triaryl rings, diaryl cycloalkanopyrazoles, and diphenyl hydrazides) were studied using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA). Partial least squares analysis produced statistically significant models with q values of 0.84 and 0.79 for CoMFA and CoMSIA, respectively. The key spatial properties were detected by careful analysis of the isocontour maps. The binding energies calculated from flexible docking correlated with inhibitory activities by the least-squares fit method. (omitted)

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1998년도 봄 학술발표회 논문집
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• pp.68-74
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• 1998

A finite element analysis for physical phenomenon which are governed by parabolic equation, has some inefficiencies caused by much computational time and large storage space. In this paper, a comparative study is performed to suggest the best efficient transient analysis algorithms for parabolic equations. First, the general finite element analysis techniques are summarized in views of formulation procedures, treatments of convection terms. and time stepping methods. Results of several combinations applied to one dimensional convection-diffusion equation and Burger equation are represented and compared using some criteria such as accuracy, stability, and computational time. Through the results, some guidelines to select a algorithm for solving parabolic equations are proposed for diffusion dominant and convection dominant cases. Finally applicability of two dimensional extension of the result is also discussed.

• 디지털융복합연구
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• 제15권11호
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• pp.85-95
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• 2017

뉴스 미디어는 대통령 후보들의 공약을 보도하면서 주관적 논평을 하며, 이는 정치 커뮤니케이션에서 중요한 의미를 가진다. 본 연구의 목적은 언론의 대통령 후보 공약에 대한 보도 특성과 신문 간 차이를 살펴보고 그 함의를 논의하는 것이다. 보수적 신문과 진보적 신문, 즉 조선일보와 경향신문에 보도된 2주간의 뉴스 기사를 표집하여, 체계화된 코딩유목에 따라 내용분석을 실시하였다. 수집된 기사에 대해 빈도분석과 신문 간 보도 논조의 차이를 검증하기 위해 교차분석을 수행하였고, 분석도구로는 SPSS 통계패키지를 이용하였다. 분석 결과, 기사 제목에서의 논조 차이는 발견되지 않았으나, 기사의 내용적 차원에서는 신문 간 논조 차이가 통계적으로 유의미하게 나타나 연구가설이 검증되었다. 이 같은 연구결과는 보수와 진보적 성격의 신문간 보도 차이로 인한 언론의 프레이밍 효과를 시사한다. 후속 연구로 지난 선거 후보들의 공약 보도와의 비교, 기사 논조의 차이에 대한 언어 사용의 심층적 분석을 위한 네트워크분석, 공약의 신문보도와 방송보도의 비교분석이 제안된다.

• 한국안전학회지
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• 제38권1호
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• pp.55-61
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• 2023

Although corporate punishment-related systems are being implemented in several countries, such as South Korea's Serious Accidents Punishment Act (SAPA), related research has mainly focused on legal issues. This study aimed to compare and analyze the SAPA and Singapore's Workplace Safety and Health Act (WSHA) and Code of Practice on Chief Executives' and Board of Directors' Workplace Safety and Health Duties (WSHD). In addition, it was attempted to draw implications to enhance the effectiveness of the CEO's safety and health duties. For this study, a comparative analysis was conducted in 3 steps. In step 1, similar overseas systems were investigated. In step 2, the system contents were classified into four viewpoints (DUTY, RESOURCE, Other factors, and Main contents), and comparison items were derived from each viewpoint. In step 3, the viewpoints were compared, and implications were derived. The following three implications were derived through comparative analyses. 1) In WSHD, additional explanation and calibration of measures clarify the CEO's role, and 2) It is easy to use for the CEO's duties by providing the resources directly. 3) Penalties for violating the proposed duties are entrusted to the existing higher-level laws. Considering this, providing detailed content and related information for the CEO would possibly improve the SAPA to fulfill his/her duties through announcements from related organizations in the future.

• 한국콘텐츠학회논문지
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• 제18권11호
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• pp.430-446
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• 2018

본 논문에서는 전파자원 활용과 관련한 정책 및 투자 방안 수립에 대한 경제적 근거 및 기초자료로서의 파급 효과 분석 방법론에 관한 비교연구를 수행하였다. 정책 및 투자 방안 간 객관적 비교 및 선정을 위해 수치적 결과를 제공하는 방법론을 분석 대상으로 하였고 수학적인 모형에 기반을 둔 정량적 방법론인 계량경제모형, 산업연관분석, 연산일반균형, 시스템 다이내믹스 방법에 대해 분석 비용 등 다양한 관점에서 효용과 한계를 비교 분석하였다. 또한, 전파자원 활용의 효과 분석 측면에서 이들 방법론을 비교하고, 분석된 방법론의 장점들을 활용하고 한계를 상쇄시키기 위해 단일 방법론들을 결합한 혼합형 모형에 대한 최근 연구결과를 논의하였다. 연구결과는 전파정책 및 투자 방안 실행의 효율성 검증을 위한 다양한 분석방법 중 분석의 목적과 우선순위에 부합하는 방법을 선정하는 데 참고 지표로 활용할 수 있다.

• 디지털융복합연구
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• 제14권2호
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• pp.427-435
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• 2016

노인자살률의 사회경제적인 요인에 대하여 다수 국가 간 비교분석은 있어도 우리나라와 특정 국가와의 집중적인 비교 연구는 없는 실정이다. 따라서 본 연구에서는 OECD 국가의 일원으로서 노인자살률의 큰 격차를 보일뿐만 아니라 노인자살률 증감률의 정반대 양상을 보이고 있는 한국과 미국을 중심으로 거시 사회 경제적 요인과 노인자살률과 어떠한 관련성을 지니는 지를 일차적으로 규명하고자 한다. 이를 위하여 한국과 미국의 지난 20년간(1990-2009)의 노인자살률과 사회구조적 요인간의 경향분석과 동시에 상관관계 분석을 활용하였다. 아울러 분석결과를 기초로 우리사회의 노인자살 예방에 대한 정책적 시사점을 제언하고자 한다.