• Journal of Korean Institute of Industrial Engineers
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• v.19 no.1
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• pp.61-71
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• 1993

We focus on a way of combining the Monte Calro methods of antithetic variates and control variates to reduce the variance of the estimator of the mean response in a simulation experiment. Combined Method applies antithetic variates (partially) for driving approiate stochastic model components to reduce the vaiance of estimator and utilizes the correlations between the response and control variates. We obtain the variance of the estimator for the response analytically and compare Combined Method with control variates method. We explore the efficiency of this method in reducing the variance of the estimator through the port operations model. Combined Method shows a better performance in reducing the variance of estimator than methods of antithetic variates and control variates in the range from 6% to 8%. The marginal efficiency gain of this method is modest for the example considered. When the effective set of control variates is small, the marginal efficiency gain may increase. Though these results are from the limited experiments, Combined Method could profitably be applied to large-scale simulation models.

• Journal of the Society of Naval Architects of Korea
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• v.61 no.1
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• pp.44-50
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• 2024

In order to reasonably predict damage extents of naval ships under in-compartment explosion (INCEX) loads, two conditions should be fulfilled in terms of accurate INCEX load generation and fracture estimation. This paper seeks to predict damage extents of various naval ships by applying the CONWEP model to generate INCEX loads, combined with the Hosford-Coulomb (HC) and localized necking (LN) fracture model. This study selected a naval ship with a 2,000-ton displacement, using associated specifications collected from references. The CONWEP model that is embedded in a commercial finite element analysis software ABAQUS/Explicit was used for INCEX load generation. The combined HC-LN model was used to simulate fracture initiation and propagation. The permanent failures with some structural fractures occurred where at the locations closest to the explosion source points in case of the near field explosions, while, some significant fractures were observed in way of the interfaces between bulkheads and curtain plates under far field explosion. A large thickness difference would lead to those interface failures. It is expected that the findings of this study enhances the vulnerability design of naval ships, enabling more accurate predictions of damage extents under INCEX loads.

• Journal of the Korean Society for Railway
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• v.3 no.1
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• pp.34-41
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• 2000

The analysis of static and dynamic characteristics of reinforced roadbed materials was performed through model and laboratory tests. The strength characteristic of reinforced roadbed materials such as HMS-25 and soil were investigated through the unconfined axial compression test, the model soil box test and the combined resonant column and torsional shear test. The unconfined axial compression strength of HMS-25 shows a steady increasement in strength due to the chemical hardening reaction between HMS-25 and water. The result of model soil box test reveals that railroad roadbed of HMS-25 is better than that of soil in several aspects, such as, bearing capacity and settlement. The combined resonant column and torsional shear test result indicates that shear modulus of HMS-25 and soil increase with the power of 0.5 to the confining pressure and linear relationship to normalized shear modulus and damping ratio.

• The Korean Journal of Pain
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• v.20 no.1
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• pp.8-14
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• 2007

Background: Anticonvulsants and antidepressants are adjuvant analgesic drugs that are used widely for treating chronic neuropathic pain syndromes. The combined analgesic effect of gabapentin and milnacipran was investigated with a rat neuropathic pain model. Methods: The rat neuropathic pain model was made by ligating the spinal nerves (L5 and L6). An intrathecal catheter was inserted into the subarachnoid space. Tactile allodynia was tested with the up-down method using von Frey hair. We determined the antiallodynic effect of intraperitoneal (I.P.) and intrathecal (I.T.) gabapentin. The combined effect of I.P. gabapentin (50 mg/kg) and milnacipran (0, 10 and 30 mg/kg) was investigated. Results: Intraperitoneal and intrathecal administration of gabapentin increased the threshold for tactile allodynia (the ED50 was 60.6 mg/kg and $45.5{\mu}g$, respectively). Co-administration of I.P. milnacipran increased the antiallodynic effect of I.P. gabapentin in a dose-dependent fashion. Conclusion: The combined administration of milnacipran and gabapentin may increase the total analgesic effect during treatment of neuropathic pain.

• Structural Engineering and Mechanics
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• v.55 no.5
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• pp.953-964
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• 2015

A model has been proposed that can predict the ultimate torsional strength of single-box multi-cell reinforced concrete box girder under combined loading of bending, shear and torsion. Compared with the single-cell box girder, this model takes the influence of inner webs on the distribution of shear flow into account. According to the softening truss theory and thin walled tube theory, a failure criterion is presented and a ultimate torsional strength calculating procedure is established for single-box multi-cell reinforced concrete box girder under combined actions, which considers the effect of tensile stress among the concrete cracks, Mohr stress compatibility and the softened constitutive law of concrete. In this paper the computer program is also compiled to speed up the calculation. The model has been validated by comparing the predicted and experimental members loaded under torsion combined with different ratios of bending and shear. The theoretical torsional strength was in good agreement with the experimental results.

• Advances in concrete construction
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• v.16 no.1
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• pp.21-34
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• 2023

This work presents a complete optimal model for trapezoidal combined footings that support a concentric load and moments around of the "X" and "Y" axes in each column to obtain the minimum area and the minimum cost. The model presented in this article considers a pressure diagram that has a linear variation (real pressure) and the equations are not limited to some cases. The classic model takes into account a concentric load and the moment around of the "X" axis (transverse axis) that is applied due to each column, i.e., the resultant force is located at the geometric center of the footing on the "Y" axis (longitudinal axis), and when the concentric load and moments around of the "X" and "Y" axes act on the footing is considered the uniform pressure applied on the contact surface of the footing, and it is the maximum pressure. Four numerical problems are presented to find the optimal design of a trapezoidal combined footing under a concentric load and moments around of the "X" and "Y" axes due to the columns: Case 1 not limited in the direction of the Y axis; Case 2 limited in the direction of the Y axis in column 1; Case 3 limited in the direction of the Y axis in column 2; Case 4 limited in the direction of the Y axis in columns 1 an 2. The complete optimal design in terms of cost optimization for the trapezoidal combined footings can be used for the rectangular combined footings considering the uniform width of the footing in the transversal direction, and also for different reinforced concrete design codes, simply by modifying the resisting capacity equations for moment, for bending shear, and for the punching shear, according to each of the codes.

• The Journal of Information Systems
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• v.19 no.4
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• pp.183-206
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• 2010

The technology acceptance model (TAM) is a lot of cited in information technology adoption and usage researches. But TAM has been conducted primarily in volitional environments of the adoption of new technology. This paper discusses technology acceptance in accounting information systems to examine TAM with Characteristics of Organizations and Individuals in mandated using Combined Guard System. Combined Guard System is a scientific guard system that is composed of automated surveillance system, automated sensing system and control system. GOP Scientific Guard System is operated by GOP unit in Korean Army O Division from 2006. In this study, using the extended technology acceptance model, we have analyzed factors which affect the usage intention of GOP Scientific Guard System in mandated using environment. Based upon previous researches, we have selected Support of management unit, Training, Perceived Risk, Subjective Knowledge and Computer Self-efficacy, perceived usefulness, perceived ease of use, and usage intention as variables and proposed a research model. We collected 253 survey questionnaires from Korean army officer and soldier who are serviced at GOP unit in O Division, and analyzed the data using SPSS 12.0 and SmartPLS 2.0M3. According to the results by PLS analysis, According to the results by PLS analysis, Training and Subjective Knowledge did not affect Perceived usefulness, but the other hypotheses were accepted. And Perceived usefulness, and Ease of use influenced the Usage intention. The results of this study will increase Characteristics of Organizations and Individuals on GOP Scientific Guard System and eventually contribute to establishing the activation of Combined Guard System.

• Structural Engineering and Mechanics
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• v.72 no.4
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• pp.443-454
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• 2019

In order to reduce the residual drift of a structure in structural engineering field, a combined structural system (dual) consisting of steel buckling-restrained braced frame (BRBF) along with shear wall is proposed. In this paper, BRBFs are used with special reinforced concrete shear walls as combined systems. Some prototype models of the proposed combined systems as well as steel BRBF-only systems (without walls) are designed according to the code recommendations. Then, the nonlinear model of the systems is prepared using fiber elements for the reinforced concrete wall and appropriate elements for the BRBs. Seismic responses of the combined systems subjected to ground motions at maximum considered earthquake level are investigated and compared to those obtained from BRBFs. Results showed that the maximum residual inter-story drift from the combined systems is, on average, less than half of the corresponding value of the BRBFs. In this research, mean of absolute values of the maximum inter-story drift ratio demand obtained from combined systems is less than the 3% limitation, while this criterion has not been fulfilled by BRBF systems.

• Korean Journal of Radiology
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• v.23 no.9
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• pp.921-930
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• 2022

Objective: To identify epidermal growth factor receptor (EGFR) mutations in lung adenocarcinoma based on ¹⁸F-fluorodeoxyglucose (FDG) PET/CT radiomics and clinical features and to distinguish EGFR exon 19 deletion (19 del) and exon 21 L858R missense (21 L858R) mutations using FDG PET/CT radiomics. Materials and Methods: We retrospectively analyzed 179 patients with lung adenocarcinoma. They were randomly assigned to training (n = 125) and testing (n = 54) cohorts in a 7:3 ratio. A total of 2632 radiomics features were extracted from the tumor region of interest from the PET (1316) and CT (1316) images. Six PET/CT radiomics features that remained after the feature selection step were used to calculate the radiomics model score (rad-score). Subsequently, a combined clinical and radiomics model was constructed based on sex, smoking history, tumor diameter, and rad-score. The performance of the combined model in identifying EGFR mutations was assessed using a receiver operating characteristic (ROC) curve. Furthermore, in a subsample of 99 patients, a PET/CT radiomics model for distinguishing 19 del and 21 L858R EGFR mutational subtypes was established, and its performance was evaluated. Results: The area under the ROC curve (AUROC) and accuracy of the combined clinical and PET/CT radiomics models were 0.882 and 81.6%, respectively, in the training cohort and 0.837 and 74.1%, respectively, in the testing cohort. The AUROC and accuracy of the radiomics model for distinguishing between 19 del and 21 L858R EGFR mutational subtypes were 0.708 and 66.7%, respectively, in the training cohort and 0.652 and 56.7%, respectively, in the testing cohort. Conclusion: The combined clinical and PET/CT radiomics model could identify the EGFR mutational status in lung adenocarcinoma with moderate accuracy. However, distinguishing between EGFR 19 del and 21 L858R mutational subtypes was more challenging using PET/CT radiomics.

• Journal of Environmental Health Sciences
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• v.31 no.6
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• pp.467-474
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• 2005

The runoff characteristics of combined sewer overflow(CSO) in the urban area of Jeonju were investigated and analyzed by using the SWMM (Storm Water Management Model) and GIS. From August to November 2004, investigations on two rainfall events were performed and flowrate, pH, BOD, COD, SS, T-N and T-P were measured. these data were used for model calibration. Using GIS technique, watershed characteristics of study area were calculated. that is, divide into sub_basin, total width, slope, make soil map etc. On the basis of the measured data and the simulation results by SWMM, it could be known that the $80-90\%$ of pollution load are discharged in early-stage storm runoff. SMC(site mean Concentration) for combined sewer system area were BOD 28.1, COD 31.5, SS 186 ppm etc. this is shown that during the rain fall, high concentration of waste was loaded to receiving water. Unit loads of combined sewer system area were BOD 306, COD 410, SS 789, T-N 79, T-P 6.8 kg/ha/yr.