• Korea-Australia Rheology Journal
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• v.16 no.2
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• pp.63-73
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• 2004

Flow in a channel with an obstruction at the entry can be reverse, stagnant or forward depending on the position of the obstruction. These flow phenomena have potential applications in the control of energy and various flows in process engineering. Parameters that affect this flow inside and around the test channel are the gap (g) between the obstruction geometry and the test channel, the Reynolds number (Re) and the length (L) of the test channel. The influence of these parameters on the flow behavior was investigated using a flat plate obstruction at the entry of the channel. A low concentration polyacrylamide solution (0.018% by weight) showing a powerlaw fluid behavior was used as the fluid in this investigation. The flow phenomena were investigated by the velocity measurement and the flow visualization and their results were compared with numerical simulation. These results of low concentration polyacrylamide solution are also compared with the results of water published elsewhere (Kabir et al., 2003). The maximum reverse flow inside the test channel observed was 20% - 30% of the outside test channel velocity at a g/w (gap to width) ratio of 1 for Reynolds numbers of 1000 to 3500. The influence of the test channel length (L) and the Reynolds number (Re) on the velocity ratio ($V_i$/$V_o$: inside velocity/outside velocity in the test channel) are also presented and discussed here.

• Proceedings of KOSOMES biannual meeting
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• 2007.11a
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• pp.177-183
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• 2007

Flow characteristics of the cylinder wake controlled with a small control cylinder were experimentally investigated by the PN (Particle Image Velocimetry) technique. Flow visualization of the flow around a circular cylinder was conducted in the Circulating Water Channel. The control cylinder having diameter of d=5mm, 10mm and 20mm was installed behind a circular cylinder of D=50mm. And the Reynolds number were $Re=4.9{\times}10^3,\;Re=9.9{times}10^3$ and $Re=1.9{\times}10^4$. In this study, the frequency characteristics of the controlled wake were analyzed by using spectral analysis of the measured wake velocity signals. As a result, the controlled wake had smaller vortex shedding frequency than that of circular cylinder wake by the effect of the control cylinder. Governing parameters of the flow control were d/D, and Reynolds number and they largely influenced the frequency characteristics of the cylinder wake. And vortex shedding frequency appeared most lowly at d=0.2D

• The KIPS Transactions:PartB
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• v.12B no.5 s.101
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• pp.543-552
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• 2005

This paper proposes the extraction of coronary arteries based on DSA(Digital Subtraction Angiography) through a texture analysis of background in the angiography. DSA is a well established modality for the visualization of coronary arteries. DSA involves the subtraction of a mask image - an image of the heart before injection of contrast medium - from live image. However, this technique is sensitive to the movement of background and can result to a wrong detection by the variance of background gray-level intensity between two images. Therefore, this paper solves a structural problem resulted from a background movement bV selecting an image which has the least difference of movement through an analysis of the similarity of background texture and proposes a method to extract only the blood vessel efficiently through local gray-level correction of the selected image. Using the coronary angiogram of 5 patients clinical data, we proved that the proposed method has the lower false-detection rate, approximately $2\%$, and the higher accuracy than the existing methods.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.1 no.1
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• pp.62-73
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• 2015

We developed an evans blue-indocyanine green-$^{99m}Tc$-human serum albumin conjugate for sentinel lymph node mapping and we describe its unique potential usage for clinical implications. This conjugate has combined the strengths of visible blue dye, near-infrared fluorescence and radioisotope into one single conjugate without any additional weakness/disadvantage. All the components of evans blue-indocyanine green-$^{99m}Tc$-human serum albumin are safe and of low cost, and they have already been clinically used. This conjugate was stable in the serum, it showed a long retention time in the lymphatic system and the lymph nodes showed a much higher signal-to-noise ratio after the conjugate was injected intradermally into the paw of mice. Both the single-photon emission computed tomography and near-infrared fluorescent images of the mice were successfully obtained at the same time as the excised sentinel lymph nodes showed blue color. The visual color, near-infrared fluorescence and gamma ray from this agent could be complementary for each other in all the steps of sentinel lymph node sampling: exploring and planning sentinel lymph node before excision with visualization of the exact sentinel lymph node location during an operation. Therefore, the triple modal agent will possibly be very ideal for sentinel lymph node mapping because of the high signal-to-noise ratio for non-invasive imaging and its complementary multimodal nature, easy preparation and safety. It is promising for clinical applications and it may have great advantages over the traditional single modal methods.

• The Korean Journal of Nuclear Medicine
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• v.25 no.1
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• pp.53-60
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• 1991

Extracorporeal shock wave lithotripsy (ESWL) with adjunctive oral litholytic therapy has proven to be a useful treatment in selected patients with gallbladder stones. To study the effect of ESWL on gallbladder dynamics, $^{99m}Tc-DISIDA$ hepatobiliary scintigraphy was done for 25 patients with symptomatic gallstones and 10 normal controls. Of these 25 patients, 15 were treated with ESWL and adjunctive oral litholytic agents (ESWL group) and 10 were treated only with oral litholytic agents (UDCA group). After overnight fast and gallbladder visualization on a routine hepatobiliary scintigraphy with 7mCi of $^{99m}Tc-DISIDA$, subjects were given fatty meal and imaged with a gamma camera interfaced to a computer (1 frame/minute for 70 minutes). A gallbladder time-activity curve was generated and latent period (LP), ejection period (EP), ejection fraction (EF) and ejection rate (ER) were calculated. ESWL group were studied before, 1day after and 2weeks after ESWL, and WDCA group were studied before and 2weeks after starting oral medication. Mean basal EF was significantly reduced in patients but other parameters were not reduced. In ESWL group, mean EF and mean ER at lday after ESWL were reduced. In 3 of them, gallbladder was not visualized at all. Two weeks after ESWL, however, all parameters were recoverd to basal level. In UDCA group, all parameters were not changed significantly during medication. We can conclude that ESWL has such immediate adverse effect on gallbladder dynamics as reducing contractility and nonvisualization of gallbladder but it has no long-term effect.

• Macromolecular Research
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• v.16 no.1
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• pp.15-20
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• 2008

The enhanced permeability and retention (EPR) effect is used extensively for the passive targeting of many macromolecular drugs for tumors. Indeed, the EPR concept has been a gold standard in polymeric anticancer drug delivery systems. This study investigated the tumoral distribution of self-assembled nanoparticles based on the EPR effect using fluorescein and radio-labeled nanoparticles. Self-assembled nanoparticles were prepared from amphiphilic chitosan derivatives, and their tissue distribution was examined in tumor-bearing mice. The size of the nanoparticles was controlled to be 330 run, which is a size suited for opening between the defective endothelial cells in tumors. The long-circulating polymer nanoparticles were allowed to gradually accumulate in the tumors for 11 days. The amount of nanoparticles accumulated in the tumors was remarkably augmented from 3.4%ID/g tissue at 1 day to 25.9%ID/g tissue at 11 days after i.v. administration. The self-assembled nanoparticles were sustained at a high level throughout the 14 day experimental period, indicating their long systemic retention in the blood circulation. The ${\gamma}$-images provided clear evidence of selective tumor localization of the $^{131}I$-labeled nanoparticles. Confocal microscopy revealed the fluorescein-labeled nanoparticles to be preferentially localized in the perivascular regions, suggesting their extravasation to the tumors through the hyperpermeable angiogenic tumor vasculature. This highly selective tumoral accumulation of nanoparticles was attributed to the leakiness of the blood vessels in the tumors and their long residence time in the blood circulation.

• Journal of the Korean Society of Marine Environment & Safety
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• v.23 no.1
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• pp.104-111
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• 2017

This research focuses on simulation and visualization of flow field characteristics inside a centrifugal pump. The 3D numerical analysis was carried out by using a numerical CFD tool, addressing a Reynolds Average Navier-Stock code with a standard k-${\varepsilon}$ two-equation turbulence model. The simulation accounts for friction head loss due to rough walls at suction, impeller, discharge areas and volumetric head loss at impeller wear ring. A comparison of performance curves between simulation and experimentation is included, and it reveals a same trend of those results with a small difference of maximum 5 %. At best efficiency point, velocity vectors are smooth but it changes significantly under off-design point, a strong recirculation appears at the outlet of impeller passages near tongue area. A relatively uniform preassure distribution was observed around the impeller in despite of the tongue. Within the volute, because of its geometry, spiral vortexes formed, proving that the flow field in this region was relatively turbulent and unsteady.

• Journal of the Korean School Mathematics Society
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• v.18 no.1
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• pp.61-82
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• 2015

This study investigated the learning process of Chines international student within a technology environment, who was studying in Korea to be well equipped as a math teacher in future. Her activities were observed and guided in a class for pre-service teachers in one university, Kyunggido, in the second semester of 2014. She experienced obstacles such as the lacks of comprehending Korean sentences, Korean math terminologies, mathematical concepts, and fidelities of technology in her learning. She was recovered by bilingual effect, visualization activities, repetition activities, and group activities. There was a learning helper who made her learning possible in a bilingual way. Thus, the bilingual education is crucial for students with multi-cultural background.

• Journal of ILASS-Korea
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• v.10 no.2
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• pp.1-9
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• 2005

An experimental study was carried out to obtain the fundamental data about the effects of radical ignition on premixture combustion. A CVC(constant volume combustor) divided into the sub-chamber and the main chamber was used. Numerous narrow passage holes are arranged between the main chamber and the sub-chamber. The products including radicals generated by spark ignition in tile sub-chamber derives the simultaneous multi-point ignition in the main chamber. We have examined the effects of the sub-chamber volume, the diameter and number of passage holes, and the equivalence $ratio({\Phi})$ on the combustion characteristics by means of burning pressure measurement and flame visualization. In a CVC, the overall burning time including the ignition delay became very short and the maximum burning pressure was slightly increased by the radical ignition(RI) method in comparison with those by the conventional spark ignition(SI) method. Combustible lean limit by RI method is extended by ${\Phi}=0.25$ compared with that by SI method. Also, In cases of charging the number and the diameter for the fixed total cross section of the passage holes, combustion period increased significantly at a sub-chamber with a single hole, but those of the other conditions had almost a similar tendency in the sub-chamber with 4 or more holes. regardless of equivalence ratio. Therefore, it was Proved that a critical cross section exists with the number of passage holes.

• Journal of the Korean Society of Clothing and Textiles
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• v.40 no.6
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• pp.1034-1044
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• 2016

This study seeks a method to objectively evaluate sensibility based on Big Data in the field of design. In order to do so, this study examined the sensibility responses on design factors for the public through a network analysis of texts displayed in social media. 'Hanbok', a formal clothing that represents Korea, was selected as the subject for the research methodology. We then collected 47,677 keywords related to Hanbok from 12,000 posts on Naver blogs from January $1^{st}$ to December $31^{st}$ 2015 and that analyzed using social matrix (a Big Data analysis software) rather than using previous survey methods. We also derived 56 key-words related to design elements and sensibility responses of Hanbok. Centrality analysis and CONCOR analysis were conducted using Ucinet6. The visualization of the network text analysis allowed the categorization of the main design factors of Hanbok with evaluation terms that mean positive, negative, and neutral sensibility responses. We also derived key evaluation factors for Hanbok as fitting, rationality, trend, and uniqueness. The evaluation terms extracted based on natural language processing technologies of atypical data have validity as a scale for evaluation and are expected to be suitable for utilization in an index for sensibility evaluation that supplements the limits of previous surveys and statistical analysis methods. The network text analysis method used in this study provides new guidelines for the use of Big Data involving sensibility evaluation methods in the field of design.