• Title/Summary/Keyword: Test center

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Effects of Vitamin A on Carcass Composition Concerning Younger Steer Fattening of Wagyu Cattle

  • Nade, T.;Hirabara, S.;Okumura, T.;Fujita, K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.16 no.3
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    • pp.353-358
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    • 2003
  • Regarding the fattening of younger cattle that the Ministry of Agriculture Forestry and Fisheries (MAFF) recommends in Japan, this study looked at vitamin A control in feed and blood and its effect on performance of production and carcass composition of Wagyu steers. Five sets from 10 Wagyu artificial identical twins were divided to into 2 groups, a restricted group (Test) and a supplied group (Control). The body weight at the finishing time of the Test was significantly lower than that of the Control (p<0.05). The daily gain from 13 to 21 months old, as the animals in the Test were fed the concentrated feed without Vitamin A, was significantly different (p<0.05) between the Test and the Control. The total daily gains for the Test and the Control for the fattening period were 0.82 kg/day and 0.93 kg/day, respectively, which showed a significant difference (p<0.01). Regarding the rib thickness, the Test was thinner than the Control. The Beef Marbling Scores of the Test and Control were 3.60 and 2.80, respectively. The muscle weight of the Test was significantly smaller than that of the Control (p<0.01). However, regarding the ratio to the carcass, the Test was significantly higher than the Control (p<0.05). For the fat weight, the Test was smaller by about 15 kg than the Control (p<0.01). Furthermore, for the fat ratio to the carcass, the Test was significantly lower than the Control (p<0.05). The bone weights of the two groups were approximately the same. Regarding the ratio of bone to carcass, the Test was higher than the Control (p<0.01). For the younger fattening method, the low level vitamin A in the serum had the effect that the muscle ratio to the carcass weight was greater and the fat was less, but the carcass and muscle weight were less.

Detecting differentially expressed genes from a mixed data set

  • Lee, Sun-Ho;Kim, In-Young;Kim, Sang-Cheol;Rha, Sun-Young;Chung, Hyun-Chel;Kim, Byung-Soo
    • Proceedings of the Korean Statistical Society Conference
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    • 2003.10a
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    • pp.173-177
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    • 2003
  • When we have both a paired data set and two independent data sets, neither a paired t-test nor a two-sample t-test can be used to detect differences between two samples. In order to identify differentially expressed genes in a mixed data set, a new test statistic is proposed.

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A Study on the Static and Dynamic Stiffness Evaluation of a High Speed Mold/Die Machining Center Structure (고속 금형가공센터 구조물의 강성평가에 관한 연구)

  • 최영휴;강영진;차상민;김태형;박보선;최원선
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2003.06a
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    • pp.102-106
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    • 2003
  • An experimental modal analysis and dynamic stiffness evaluation of a moving body structure of a high speed machining center are presented in this paper. The natural frequencies and corresponding modes, and dynamic compliance of a moving body structure of high speed machining center are investigated by using F.E.M., hydraulic exciter test, and impulse hammer test. The lowest three natural frequencies were found to be 56.6 Hz, 112.7 Hz, and 142.7 Hz by FEA respectively, while those were 55 Hz, 112 Hz, 131 Hz by experimental analysis. Furthermore, both computed and measured absolute dynamic compliances of the moving body structure in iso-direction showed good agreement especially at the first two mode frequencies. With our experimental data, the dynamic characteristics of the machining center can be exploited to get a new development of structural dynamic design and modification.

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A STUDY ON THE RECOMBINANT HUMAN INTERFERON ${\alpha}$A(LBD-007) FOR PRIMARY EYE AND SKIN IRRITATION IN RABBITS

  • Park, Jong-Il;Kim, Sung-Hoon;Han, Sang-Seop;Roh, Jung-Koo
    • Toxicological Research
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    • v.9 no.1
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    • pp.119-123
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    • 1993
  • LBD-007, a newly developed recombinant human interferon ${\alpha}$A, was tested for primary eye and skin irritation in male New Zealand White rabbits. In the primary eye irritation test, 0.1ml of a solution of LBD-007 was instilled into the eye. In rinsing group, the eye was washed with water 30 seconds after instillation. No reaction was observed at the cornea, iris and conjunctivae by LBD-007. In the primary skin irritation test, LBD-007 was applied to the back of rabbits for 24 hours. Primary irritation index was "0" in test and control sites of all animals. Thus LBD-007 was evaluated as a non-irritant on the basis of the criteria of Draize et al.,(1994).

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Antidepressant Effect of the Subchronic Administration of the Methanolic Extract of Wild-ginseng and Cultivated-ginseng in Mice Tail Suspension Test (산삼과 인삼 메탄올 추출물 아만성 복용의 Mice Tail Suspension Test에서의 항우울 효과에 대한 비교연구)

  • Kwon, Sun-Oh;Choi, Soo-Min;Kim, Myung-Hwan;Lee, Bom-Bi;Park, Moo-Won;Lee, Hye-Jung;Park, Hi-Joon;Hahm, Dae-Hyun
    • Journal of Acupuncture Research
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    • v.26 no.4
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    • pp.99-106
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    • 2009
  • Objectives : The antidepressant effect of the subchronic administration of the methanolic extract of wild ginseng(WG) was investigated compared with that of cultivated ginseng(CG, panax ginseng) extract. Methods : To assess the antidepressant effect of the ginseng extracts, tail suspension test(TST) was executed in mice after daily administration of WG or CG extract for five consecutive days. Results : The WG extract at daily dose of 600mg/kg significantly reduced the total duration of immobility in the TST, whereas there was no significant reduction at daily dose of 300mg/kg WG and 600mg/kg CG. There were no individual differences between experimental groups in open field test (OFT) to evaluate psychostimulant effects of WG or CG extract. In the high performance liquid chromatography(HPLC) analysis of the extracts, it was found that WG included four times more ginsenoside Rg1 and Re, three times more Rf, and six times more Rb1 and Rc than CG. Conclusions : It is suggested that WG extract has stronger antidepressant effect than CG extract, which means it includes more antidepressant compounds than CG.

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Factors Associated with Indeterminate and False Negative Results of QuantiFERON-TB Gold In-Tube Test in Active Tuberculosis

  • Cho, Ki-Won;Cho, Eun-Ha;Kwon, Soo-Hoon;Im, Sang-Hyuk;Sohn, In;Song, Sook-Hee;Kim, Hye-Ok;Kim, Su-Hyun
    • Tuberculosis and Respiratory Diseases
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    • v.72 no.5
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    • pp.416-425
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    • 2012
  • Background: The sensitivities and specificities of interferon-gamma release assays (IGRAs) vary among different population studies, and the data on the routine use of IGRAs are limited. The aim of this study was to evaluate the role of QuantiFERON-TB Gold In-Tube (QFT-GIT) test in the diagnosis of active tuberculosis. Methods: We conducted a prospective study, enrolling 77 patients with suspected pulmonary tuberculosis (TB), at a secondary care teaching hospital in Seoul. Results: In total, 12 (15.6%) patients showed indeterminate results due to positive control failure on the QFT-GIT test. Indeterminate results were significantly associated with the elderly, history of the intensive care unit stay, lymphocytopenia, especially low CD4 count, increased C-reactive protein and decreased protein levels. Of the 77 patients, 44 (57.1%) were diagnosed with active pulmonary tuberculosis, and the percentage of false negative results of the QFT-GIT was 36.4% (vs. 31.8% with TST). In the TB group with >65 years old (n=12), the proportions of the indeterminate (33.3% vs. 3.1%) and the false negative results (58.3% vs. 25.0%) of the QFT-GIT were significantly higher than in the younger TB group (n=32). Conclusion: Indeterminate and false negative results of QFT-GIT test were not infrequent in tuberculosis, especially in the elderly. Care should be considered for the interpretation with the elderly, immunocompromised, chronic and severely diseased patients.

Introduction to the standard reference data of electron energy loss spectra and their database: eel.geri.re.kr

  • Jeong Eun Chae;Ji-Soo Kim;Sang-Yeol Nam;Min Su Kim;Jucheol Park
    • Applied Microscopy
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    • v.50
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    • pp.2.1-2.7
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    • 2020
  • Electron energy loss spectroscopy (EELS) is an analytical technique that can provide the structural, physical and chemical information of materials. The EELS spectra can be obtained by combining with TEM at sub-nanometer spatial resolution. However, EELS spectral information can't be obtained easily because in order to interpret EELS spectra, we need to refer to and/or compare many reference data with each other. And in addition to that, we should consider the different experimental variables used to produce each data. Therefore, reliable and easily interpretable EELS standard reference data are needed. Our Electron Energy Loss Data Center (EELDC) has been designated as National Standard Electron Energy Loss Data Center No. 34 to develop EELS standard reference (SR) data and to play a role in dissemination and diffusion of the SR data to users. EELDC has developed and collected EEL SR data for the materials required by major industries and has a total of 82 EEL SR data. Also, we have created an online platform that provides a one-stop-place to help users interpret quickly EELS spectra and get various spectral information. In this paper, we introduce EEL SR data, the homepage of EELDC and how to use them.

The Establishing Test Method of Bactericidal Activity and the Evaluating of Korean Disinfectants/Sanitizers Efficacy (살균소독력 시험법 확립 및 살균소독력 평가)

  • Kim, Hyung-Il;Lee, Kwang-Ho;Kwak, In-Shin;Eom, Mi-Ok;Jeon, Dae-Hoon;Sung, Jun-Hyun;Choi, Jung-Mi;Kang, Han-Saem;Kim, Yong-Soo;Kang, Kil-Jin
    • Korean Journal of Food Science and Technology
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    • v.37 no.5
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    • pp.838-843
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    • 2005
  • Bacterial suspension test was used to establish Standardization Test Method to investigate bactericidal activity of disinfectant/sanitizer product. Using acceptable verification methodology, test substance showing 5 log or higher reduction in viable count against Escherichia coli ATCC 10536 and Staphylococcus aureus ATCC 6538, representing Gram-negative and -positive bacteria, respectively, under test conditions for $5\;min{\pm}10\;sec\;at\;20{\pm}1^{\circ}C$ was considered to have sanitizing capability. All disinfectant/sanitizer products tested under manufacturer's recommended in-use condition gave good reduction values against major food-poisoning bacteria. This standardized method was valuable for evaluating efficacy of disinfectants/sanitizers and could be used as Standardization Test Method for assessing bactericidal activity

Validation of the OncoHepa test, a multigene expression profile test, and the tumor marker-volume score to predict postresection outcome in small solitary hepatocellular carcinomas

  • Ha, Su-Min;Hwang, Shin;Park, Jin Young;Lee, Young-Joo;Kim, Ki-Hun;Song, Gi-Won;Jung, Dong-Hwan;Yu, Yun-Suk;Kim, Jinpyo;Lee, Kyoung-Jin;Tak, Eunyoung;Park, Yo-Han;Lee, Sung-Gyu
    • Annals of Surgical Treatment and Research
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    • v.95 no.6
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    • pp.303-311
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    • 2018
  • Purpose: OncoHepa test is a multigene expression profile test developed for assessment of hepatocellular carcinoma (HCC) prognosis. Multiplication of ${\alpha}$-FP, des-${\gamma}$-carboxy prothrombin (DCP) and tumor volume (TV) gives the ${\alpha}$-FP-DCP-volume (ADV) score, which is also developed for assessment of HCC prognosis. Methods: The predictive powers of OncoHepa test and ADV score were validated in 35 patients who underwent curative hepatic resection for naïve solitary HCCs ${\leq}5cm$. Results: Median tumor diameter was 3.0 cm. Tumor recurrence and patient survival rates were 28.6% and 100% at 1 year, 48.6% and 82.9% at 3 years, and 54.3% and 71.4% at 5 years, respectively. The site of first tumor recurrence was the remnant liver in 18, lung in 1, and the peritoneum in 1. All patients with HCC recurrence received locoregional treatment. OncoHepa test showed marginal prognostic significance for tumor recurrence and patient survival. ADV score at 4log also showed marginal prognostic difference with respect to tumor recurrence and patient survival. Combination of these 2 tests resulted in greater prognostic significance for both tumor recurrence (P = 0.046) and patient survival (P = 0.048). Conclusion: Both OncoHepa test and ADV score have considerably strong prognostic power, thus individual and combined findings of OncoHepa test and ADV score will be helpful to guide postresection surveillance in patients with solitary HCCs ${\leq}5cm$.