• Title/Summary/Keyword: Test 1.1 & 2.1

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Evaluation of immunogenicity of the 2008-2009 seasonal influenza vaccines by microneutralization test

  • Kim, Seung Youn;Kim, Yun Kyung;Eun, Byung Wook;Kim, Nam Hee;Kang, Eun Kyeong;Lee, Byong Sop;Lim, Jung Sub;Lee, Jun Ah;Kim, Dong Ho
    • Clinical and Experimental Pediatrics
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    • v.55 no.12
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    • pp.474-480
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    • 2012
  • Purpose: For evaluating the immunogenicity of an influenza vaccine, the microneutralization (MN) test has a higher sensitivity and specificity as compared to the hemagglutination inhibition (HI) test. However, the MN test is more time consuming and is difficult to standardize. We performed the MN test to determine its usefulness as an alternative or complementary test to the HI test for evaluating the immunogenicity of influenza vaccines. Methods: We compared the MN test with the HI test using 50 paired samples taken from a previous clinical study (2008-2009) in Korean children under 18 years of age. Results: The linear correlation coefficients of the 2 tests for H3N2, H1N1, and influenza B were 0.69, 0.70, and 0.66, respectively. We identified a high index of coincidence between the 2 tests. For an influenza vaccine, the postvaccination seroprotection rates and seroconversion rates determined by the MN test were 78.0% and 96.0%, 90% and 42.0%, and 42.0% and 48.0% for H3N2, H1N1, and influenza B, respectively. Geometric mean titer fold increases of H3N2, H1N1, and influenza B were 2.89, 5.04, and 4.29, respectively, and were 2.5-fold higher. We obtained good results in the evaluation of the immunogenicity of the 2008-2009 seasonal influenza vaccines. Conclusion: We found that the MN test was as effective as the HI test. Therefore, we suggest that the MN test can be used as an alternative or complementary test to the HI test for evaluating the immunogenicity of influenza vaccines.

L1-2 Disc Herniations : Clinical Characteristics and Surgical Results

  • Lee, Sang-Ho;Choi, Seok-Min
    • Journal of Korean Neurosurgical Society
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    • v.38 no.3
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    • pp.196-201
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    • 2005
  • Objective : Among upper lumbar disc herniations, L1-2 disc herniations are especially rare. We present the specific clinical features of L1-2 disc herniation and compared results of different surgical options. Methods : The authors undertook a retrospective single institution review of the patients who underwent surgery for L1-2 disc herniation. Thirty patients who underwent surgery for isolated L1-2 disc herniations were included. Results : Buttock pain was more frequent than anterior or anterolateral thigh pain. Standing and/or walking intolerance was more common than sitting intolerance. The straight leg raising test was positive only in 15 patients [50%]. Iliopsoas weakness was more frequent than quadriceps weakness. Percutaneous discectomy group demonstrated worse outcome than laminectomy group or lateral retroperitoneal approach group. Conclusion : Standing and/or walking intolerance, positive femoral nerve stretch test, and iliopsoas weakness can be useful clues to the diagnosis of L1-2 disc herniation. Posterior approach using partial laminectomy and medial facetectomy or minimally invasive lateral retroperitoneal approach seems like a better surgical option for L1-2 disc herniation than percutaneous endoscopic discectomy.

Identification of K1 Polysaccharide Antigen of Escherichia coli Isolates from Urine Specimens of Urinary Tract Infections in Children (요로감염소아의 오줌에서 분리한 대장균 K1 다당류 항원의 동정)

  • 정희곤
    • The Korean Journal of Food And Nutrition
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    • v.11 no.4
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    • pp.416-419
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    • 1998
  • Identification of escherchia coli K1 polysaccharide antigen isolated from urine specimens of urinary tract infections in children were performed from of 1992 to 1993 in Kyoto, Japan. The serotypes of E. coli were categorized that O1:H7, O2:H6, O2:H7, O16:H6, O18:H7, O18:H ̄, and O135:H44 among 14 strains isolated from urine specimens of urinary tract infections in children by the serological test. And, one strain (O18:H ̄, isolation rate: 7.1%) of E. coli K1 polysaccharide antigen among 14 strains were isolated from urine specimens of urinary tract infections in children by the bacteriophage test.

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Is there any determinant for successful distraction osteogenesis of the mandible in hemifacial microsomia patients? (반안면왜소증 환자의 하악골 신장술시 치료결과의 차이에 기여하는 인자)

  • Baek Seung-Hak
    • Korean Journal of Cleft Lip And Palate
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    • v.7 no.2
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    • pp.77-91
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    • 2004
  • 본 연구의 목적은 반안면왜소증 환자의 하악골 신장술시 초기 치아골격 특성들 중에서 치료결과의 차이에 기여하는 인자를 찾는 것이다. 치료전의 치아골격 특성, 골신장술의 효과와 그 유지상태를 관찰하기 위하여 골신장술 직전(T0), 직후(T1), 추적 2년후(T2)에 측모와 정모 두부방사선 계측사진을 촬영하여 전후방, 수직치아, 비대칭 항목들을 계측하였다. T2 시기의 계측 결과에 따라서 환자들을 1군(양호군, 10명)과 2군(불량군, 9명)으로 분류하였다. 두 군에서 각 시기와 T0-T1, T1-T2 동안의 변화량의 차이를 Mann-Whitney U test, Wilcoxon signed independent t-test, rank test, ANOVA test를 사용하여 분석하였다. pruzansky type이 골신 장술의 성공과 실패 여부와 관계가 깊게 나타났다. T0 시기에 2군은 1군에 비하여 하악골이 후방위치되었고, 하악지 고경(ramus height)이 짧았고, 하악각(gonial angle)이 컸으며, 이환측 하악지가 내측경사되었고, 이환측으로의 이부변위(chin point deviation)가 크게 나타났다. 1군에서 골신장술의 주요한 효과는 하악지 고경의 증가, 하악골의 전방위치, 하악각의 증가, articular angle의 감소에 따른 하약골의 반시계방향 회전, 이환측의 하악지 경사의 증가, 교합면경사와 이부변위의 개선으로 나타났다. 그러나 2군에서는 골신장술을 시행했을 때 1군에 비하여 하악골이 시계방향으로 회전되었고 하악지 고경의 증가량이 작게 나타났다. T2 시기에 2군에서는 하악골의 반시계방향 회전이 나타났고, 하악지 성장이 일어나지 않았으나, 1군은 반대의 경향을 보였다. 이러한 인자들이 골신장술 결과의 차이에 기여하는 것으로 생각된다.

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Oxidative Stability of Korean Traditional Cake added Ginseng (인삼을 첨가한 한과 강정의 산화안정성에 관한 연구)

  • Lee Jung-Suk;Chang Young-Sang;Oh Man-Jin
    • The Korean Journal of Community Living Science
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    • v.17 no.3
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    • pp.43-53
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    • 2006
  • In order to improve on the stability during the storage of Han-gwa, this study measured peroxide value, AOM test of ginseng and antioxidants added to Han-gwa. 1.2% of ginseng added to Han-gwa consists of moisture (3.37%), protein(1.30%), lipids (11.54%), carbohydrate(82.45%) and ash (1.34%). The hardness of Han-gwa was 257.7 for 1.2% of ginseng added to Han-gwa and 269.8 for Han-gwa without ginseng. The expansion coefficient of Han-gwa including 1.2% of ginseng was 12.9 magnification to Bandegi, indicating that it was inversely proportioned to the amount of ginseng. The induction period of the AOM test according to the concentration of ginseng in Han-gwa was extended to $0.53{\sim}0.83$ of magnification than the test of Han-gwa without ginseng. According to changes in AOM, acid value, peroxide value and thiobarbituric acid value of Han-gwa with various packing materials, PP multilayer film packing was the most effective material for storage of Han-gwa at 30C. 1.2% of ginseng added to Han-gwa and rosemary extract in a panel test was the most effective, and using PP multilayer film packing for Han-gwa was found to be the most useful method.

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KSLV-I Kick Motor Nozzle Hydro-Pressure Test (KSLV-1 Kick Motor 노즐 수압시험)

  • Yoo, Jae-Suk;Kim, Byung-Hun;Cho, In-Hyun;Jang, Young-Soon
    • Aerospace Engineering and Technology
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    • v.7 no.1
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    • pp.202-209
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    • 2008
  • KSLV-1 2nd stage Kick Motor Nozzle was exposed to high temperature and pressure during the firing. Under the high pressure environment, Kick Motor Nozzle hydro-pressure test was done for verifying the structural safety of the nozzle. The differences with the KM hydro-pressure test [1] are that the real immerged heat resistance material is assembled and the throat heat resistance material is similar with the real one. The hydro-pressure tests were done for the two times of the 125 % of MEOP (975 psi) and the 153 % of the MEOP.

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A survey on the infection rate of Dirofilaria immitis of dogs in Daegu area (대구지역 개의 심장사상충 감염실태)

  • Lim, Hyun-Sook;Cho, Yoo-Joung;Suh, Dong-Kyun;Song, Dong-Jun;Lee, Chun-Sik;Bae, Young-Chan
    • Korean Journal of Veterinary Service
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    • v.26 no.2
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    • pp.129-134
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    • 2003
  • A survey of canine heartworm(Dirofilaria immitis) infections among dogs in Daefu area was performed from February 2000 to October 2002 using a microfilarial test and an antigen test(AGEN$^{TM}$ Canine heartworm). The infection rate of 220 dogs(96 males, 124 females) was 23.2%(51/22) by the microfilarial test, but was 23.6%(52/220) by the antigen test, revealing that 1 of 52 antigen-positive dogs were microfilaria-negative in the peripheral blood. All dogs that were microgilaria-positive were also antigen-positive. The infection rates of heartworm in dogs at the age of < 1, 1-3, 4-6, 7-11 and 12-15 years were 2.7%, 17.4%, 41.0%, 42.9% and 57.1%, respectively. Based on the fact that the antigen test is more accurate than the microfilaria test. The infection rates of heartworm in dogs by housing of indoor and outdoor were 6.9% and 46.4%, respectively. Based on the fact that outdoor housing is more infectious than indoor housing.

A Content Analysis of the test of the National Examination for Registration Nurses in Korea over 3 years (간호사 국가고시문제의 내용분석)

  • 서문자;윤순녕;유지수;송지호;최경숙
    • Journal of Korean Academy of Nursing
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    • v.26 no.1
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    • pp.73-93
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    • 1996
  • This study aimed to analyse the test contents of the national examination for the registered nurses (NERN) over 3 years from 1991 to 1993 in Korea. In recent years in Korea, the MCQ(multiple choice question) has been showing to be a highly recognized method for assessing the qualification of registered nurses. Unfortunately, nursing faculties have found NERN had some bad MCQs through having evaluation workshop for Some MCQs often provide so many unwriting clues which become a bias of the results, and some items fell into the category of the lower level of educational taxonomy such as isolated recall a fact or data. Frequently the stems of the questions are ambigous, unclear, disputable, esoterical or trivial. Considering those fallacies of the national examination, it is very critical to review the test items to see whether it is of high quality, is more fair, reliable and objective in depth. Therefore, this study was done to provide data for the improvement of the test contents as well as the teachers's assessment skill. For this study, the ad hoc committee was composed of 16 members, including 5 education board members of Korean Academic Nurses Association and 11 nursing faculty members. This committee had one day panel discussion and filled the checklist for this study. The process of analysing data was held over 10 times during 1992-1994. The analysis focussed on educational taxonomy such as cognitive domain(knowledge), psychmotor domain (skill), affective domain(attitude) and the level of learning such as recall, understanding, problems solving, and learning area of theory and practice, and the learning content categorised by nursing process and disease process. The test analysed using difficulty index and the structure of the test items was analysed. The conclusions and suggestion as follows : 1. In learning area, the average ratio of the theory and practice was 1 : 1.1 which was less than 1 : 2 suggested by Korean National Health Institute, and the ratio was different by the 8 leaning subjects of nursing. 2. In category of the educational taxonomy, the knowledge domain was emphasized mostly(79. 7%), the skill domain was 14.9%, and the attitude domain was 5.4% only. 3. In the level of learning, generally, the test items of the level of recall(45.5%) and the understanding(46.3%) were covered almost and the problem solving was 8.1%. 4. In the learning contents, generally, the test items related to nursing process was 67.2% and that of disease process was 32.8%. However, this proportion was different by the 8 leaning subjects. Even though the nursing diagnosis has been emphasized in nursing curricula recently, the test items of this was identified very few. 5. In the structure of the test item, some were not clear, incorrect grammar, unclear description and some have clues to answer. 6. In the item analysis, the non-acceptable level of the difficulty index (means too easy) was 65.7%, and the acceptable level was 33.9%. Considering the results we would like to suggest the followings, 1. Since the test items of knowledge domain was dominant, the test items of the practice domain and attitude domain should be emphasized more. 2. The regular review and analysis of NERN should be arranged in order to improve the quality of the test items which will give influence to the nursing education positively.

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IEEE1149.1 Boundary Scan Design for the Detection of Delay Defects (지연고장 탐지를 위한 IEEE 1149.1 바운다리스캔 설계)

  • Kim, Tae-Hyeong;Park, Seong-Ju
    • Journal of KIISE:Computer Systems and Theory
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    • v.26 no.8
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    • pp.1024-1030
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    • 1999
  • IEEE 1149.1 바운다리스캔은 보드 수준에서 고장점검 및 진단을 위한 테스트 설계기술이다. 그러나, 바운다리스캔 제어기의 특성상 테스트 패턴의 주입에서 관측까지 2.5 TCK가 소요되므로, 연결선상의 지연고장을 점검할 수 없다. 본 논문에서는 UpdateDR 신호를 변경하여, 테스트 패턴 주입에서 관측까지 1 TCK가 소요되게 함으로써, 지연고장 점검을 가능하게 하는 기술을 소개한다. 나아가서, 정적인 고장점검을 위한 테스트 패턴을 개선해 지연고장 점검까지 가능하게 하는, N개의 net에 대한 2 log(n+2) 의 새로운 테스트패턴도 제안한다. 설계와 시뮬레이션을 통해 지연고장 점검이 가능함을 확인하였다.Abstract IEEE 1149.1 Boundary-Scan is a testable design technique for the detection and diagnosis of faults on a board. However, since it takes 2.5TCKs to observe data launched from an output boundary scan cell due to inherent characteristics of the TAP controller, it is impossible to test delay defects on the interconnect nets. This paper introduces a new technique that postpones the activation of UpdateDR signal by 1.5 TCKs while complying with IEEE 1149.1 standard. Furthermore we have developed 2 log(n+2) , where N is the number of nets, interconnect test patterns to test delay faults in addition to the static interconnect faults. The validness of our approach is verified through the design and simulation.

Epidemiological studies on bovine tuberculosis in mass outbreak region (우결핵 집단 발생직역에 대한 역학적 고찰)

  • Cho, Bum-Jun;Chu, Keum-Suk;Cho, Young-Suk;Kang, Mi-Seon;Lee, Jeong-Won
    • Korean Journal of Veterinary Service
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    • v.32 no.2
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    • pp.119-124
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    • 2009
  • The epidemiological survey of mass outbreak region of bovine tuberculosis from January of 2007 through May in 2009. The results were enumerated as follows. The results of tuberculin skin test are: 7 (0.4%) out of 1,697 in 2007, 61 (2.8%) out of 2,163 in 2008, 80 (4.9%) out of 1,639 in 2009. The sex and age distribution among the incidence of positive: 135 (91.8%) out of 147 in female, 12 (8.2%) in male. Among female, age 1: 6.1%, age 2: 30.6%, 3: 38.8%, 4: 14.2%, 5: 0.7% and 6: 1.4%. Among male, age 1: 4.1%, 2: 1.4%, 3: 2.7% and more frequent occurrence in age 3, 38.8% in female and 2.7% in male. The rate of recurrence by farms: recurrence 1: 6 (35.3%), 2: 9 (52.9%), 3: 1 (5.9%), 6: 1 (5.9%), The recurrence rate of 2 or more was 64.7%. The ELISA test result among 114 heads over 14 farms: 75 (65.8%) showed positive and 39 (34.2%) negative. Geographical distribution of recurrence is characterized as concentrated along the major traffic and stream crossing the village, and spread from the high elevation to downward area.