The potential importance of proteomic approaches has been clearly demonstrated in other fields of human medical research, including liver and heart disease and certain forms of cancer. However, reproductive researches have been applied to proteomics poorly. Proteomics can be defined as the systematic analysis of proteins for their identity, quantity, and function. It could increase the predictability of early drug development and identify non-invasive biomarkers of toxicity or efficacy. Proteome analysis is most commonly accomplished by the combination of two-dimensional gel electrophoresis(2DE) and MALDI-TOF(matrix-assisted laser desorption ionization-time of flight) MS(mass spectrometry) or protein chip array and SELDI-TOF(surface-enhanced laser desorption ionization-time of flight) MS. In addition understanding the possessing knowledge of the developing biomarkers used to assess reproductive biology will also be essential components relevant to the topic of reproduction. The continued integration of proteomic and genomic data will have a fundamental impact on our understanding of the normal functioning of cells and organisms and will give insights into complex cellular processes and disease and provides new opportunities for the development of diagnostics and therapeutics. The challenge to researchers in the field of reproduction is to harness this new technology as well as others that are available to a greater extent than at present as they have considerable potential to greatly improve our understanding of the molecular aspects of reproduction both in health and disease.
The incentive and reasons to publish FIDIC Conditions of Contract for Design, Build and Operate Projects(DBO Form) are manifold. It is partly a response to the increasing need for sophisticated project delivery methods in both the public and private sectors and the already widespread use of the FIDIC Yellow Book with operation and maintenance obligations and partly a response to the challenge to decrease maintenance cost to a minimum by means of a new procurement route. As a result, FIDIC has developed a new model form to meet this market place requirement. On the other hand, FIDIC did not simply adapt the Yellow Book but has developed a new form from it, whilst preserving the style of the already known FIDIC Forms and maintaining the wording where it was not necessary to change it for the purposes of a DBO Form. Moreover DBO Form fills up supposed gaps in other FIDIC Forms and ameliorates the claim management and dispute management framework. FIDIC DBO approach may be shortly summarized as follows. First, DBO Form provides for single project responsibility. Second, DBO Form has the clear objective of ensuring the use of a most reliable and efficient technology at the lowest life-cycle cost. Third, DBO Form is intended to operate as an effective quality increase in the design and construction of projects. Fourth, DBO Form is intended to provide significant benefits with regard to system integration and reduction of risks. Fifth, DBO Form accelerates and enhances completion schedule compliance. Sixth, DBO takes care of all three supporting pillars of sustainability(including economical, environmental and social elements). DBO Form is obviously a good starting point for negotiations and the preparation of calls for tenders, thus saving the parties time and money. However, existing cultural and legal differences, particular local conditions and the particular needs of some branches of the industry may require the form to be adapted according to the particular needs of a project. And Civil law practitioners are strongly recommended to verify carefully the underlying legal concepts and background of each clause of the General Conditions in order to avoid unnecessary and sometimes unnatural changes and amendments being made. Note that when preparing the Particular Conditions ensure that terminology is consistent and that existing inherent concepts should not be ignored.
Journal of the Korea Academia-Industrial cooperation Society
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v.11
no.8
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pp.2983-2988
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2010
The train control system used in Gyeongbu-line is classified in ATC, IXL and CTC. Domestic railway signaling systems are being developed by electrification. In these systems the electrification of interlocking reaches 57% and the safety equipments of railway crossings in trackside devices have completed their development into an integrated system. Block systems of all the existing sections have not yet electrified and integrated so that they need a number of complement in terms of construction and maintenance. For ABS currently used in existing domestic lines, and LEU being installed in Gyeongbu and Honam lines, although a train is controlled by the signaling information of the same train in the same location, the system is separately installed so that the same information is separately divided and transmitted at the each distinct system. Therefore, in the conventional ABS and LEU, there are a lot of duplicate installed compartments such as lamp detection and a power supply unit. Hence, we have a lot of problems: for maintenance, a lot of manpower and costs need to be invested and the overall manufacturing costs get higher, as well as the construction costs by duplicate. Therefore, this paper suggest design to develop an integrated electronic Block Control Unit by the integration of the currently used ABS, and communication and electronic technology. We are to monitor and manage the block systems in the corresponding station by integrating. And we are to transmit information together with LEU, which is an ATS wayside transmitter.
Journal of the Korea Academia-Industrial cooperation Society
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v.17
no.7
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pp.400-409
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2016
The geospatial information industry has the advantage of being able to converge with other industries to create new value. Therefore, efforts are underway to promote the growth of this dwindling national industry by endorsing policies and initiatives to promote its convergence with other industries. In this study, feedback was collected from experts in various fields through three rounds of polls using the Delphi method. The poll results were used to investigate the causes of hindrance to the growth of the geospatial information industry and to build a comprehensive solution to this problem. As a result, 27 strategies were constructed based on the users' requirements related to policy, data and service, including the demands for establishing public polling methods, enhancing data quality and advertisement. Since the coefficient of variance fell between 0.11 and 0.20 in the importance evaluation, an amicable consensus was reached between the experts. Considering that the convergence of industries is achieved through the integration of various types of technology and information, it is important to consider the requirements of users in different industries. In this respect, the results of this study will serve as a useful base for constructing mid-to-long term road maps to promote the development of the geospatial information industry.
The purpose of this study was to examine the effect of the film 'The Island' on 2nd year nursing students' nursing informatics (NI) competency. The participants were sixty-eight students in a baccalaureate nursing program of a private university, taking the course, 'Nursing & Informatics' in the 2012 fall semester. Over the 15 weeks, the film was used for five weeks as introduction to NI, peer-to-group discussions, and self-reflection on lessons learned regarding NI. A qualitative content analysis was used to explore the students' experiences and perceptions on their NI competency. As a result, students signified the NI concept as the assessment of biometrics data, promotion of optimal health with the support of various technologies, and integration of patient-centered care into routine practice. They also highlighted the importance of security and safety measures as well as high quality health technology including the ubiquitous health monitoring system. Overall, the lesson outcomes of the course were met. As a supportive, instructional strategy, the use of the movie, 'The Island', was effective for nursing students in achieving NI competencies. Further study is warranted to determine if movies can be used as a means of continuing education to improve informatics competences in healthcare professionals.
In this paper, parafoil airdrop system has been designed and analyzed. 6-degrees of freedom (6-DOF) model of the parafoil system is set up. Nonlinear model predictive control (NMPC) and Proportion integration differentiation (PID) methods were separately applied to adjust the flap yaw angle. Compared the results of setting time and overshoot time of yaw angle, it is found that the of yaw angle is more stable by using PID method. Then, trajectory following controller was designed based on the simulation results of trajectory following effects, which was carried out by using MATLAB. The lateral offset error of parafoil trajectory can be eliminated by its lateral deviation control. The later offset deviation reference was obtained by the interpolation of the current planning path. Moreover, using the designed trajectory, the trajectory following system was simulated by adding the wind disturbances. It is found that the simulation result is highly agreed with the designed trajectory, which means that wind disturbances have been eliminated with the change of yaw angle controlled by PID method.
Journal of the Korea Academia-Industrial cooperation Society
/
v.19
no.4
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pp.276-292
/
2018
This study was conducted to investigate the trends in domestic and international disaster-related research through a systematic review of the literature and to establish a basis for future disaster-related countermeasures and development directions. A related literature search was conducted through the domestic and foreign databases through the combination of disaster-related terms from 2000 until February 28, 2017, and 79 articles were used in the analysis based on selection and exclusion criteria of 177 total documents. As a result of the research, 31.6% of disaster research type was quantitative studies, and 29.1% of the major disciplines were medical research. In addition, there were engineering(18.9%), public administration(13.9%), and nursing(11.4%). In foreign literature, there are many triage studies for the classification of patients in multiple lesions. On the other hand, only 30.4% of total triage studies in Korea were detected. Most of them were related to triage development, triage evaluation, triage research, and reviews. In addition, according to the disaster nursing capacity framework of the International Council of Nurses, 72.3% of studies were related to the response phase. Future research on disasters requires interdisciplinary convergence, patient classification, and technology integration to improve the survival rate of multiple injuries, and an integrated system based on the results of collaborative research among interdisciplinary groups is needed.
Choi, Yong Jun;Choi, Mi Lim;Lee, Jeong Chan;Jung, Yong Gyu
Journal of Service Research and Studies
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v.4
no.2
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pp.1-10
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2014
According to recent trends in technological advances and globalization, medical device industry may improve the constitution to meet worldwide medical equipment management system. Also it is holding a strand of mitigation to reach the level of international regulation. In addition, recent legislation tends are to stay limited ranges of industry regulations at least and take as open attitude for integration of new technologies combined medical devices. A greater environmental risk is not likely to work in medical technology, Combinded medical device is used as close to zero risk in most of the human body, which is classified as Class 1. Even medical device such as little or no risk in handling, it is possible to minimize the unnecessary administrative power and a waste of time to occur. For the medical device may be improving people's choices and access, medical equipment operator is expanding to include dealers, because this will be exalted to particular area of the business of the company. In this paper, we investigate the legal prerequisites for the establishment of a medical device. And propose improved regulations in topics in order to facilitate the repair and distribution markets for fair trade.
Journal of Korean Home Economics Education Association
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v.32
no.2
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pp.117-139
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2020
The purpose of this study was to develop curriculum of the elementary, and secondary school home economics that integrates three systems of action and to prepare a plan for convergence education in home economics curriculum. To achieve this goal, the characteristics of elementary, secondary school dietary curriculum integrating three systems of action, the focus of development, core competencies, and goals were derived through the review of literature. In this study, we set up perennial and sub-practical problems and selected content elements. The contents system of the developed curriculum was modified and supplemented by examining the validity of experts, and the achievement standard of the middle school home economics dietary education curriculum was developed by integrating the three systems of action. The content system of the elementary, and secondary school home economics curriculum that integrated the three systems of action is centered on practical problems, and the perennial problem is 'What should we do to practice healthy dietary life?' There are five areas of this curriculum: 'health and diet', 'food planning', 'food purchase and management', 'cooking', and 'meal', and the scope of curriculum is repeatedly expanded to 'personal and family', and 'social'. The practical problems in the five areas are composed of 10 practical problems in the two dimensions (personal & family, and society), and the practical problems and contents elements are spiralled by applying the principle of integration. The contents of this curriculum were compared with the achievement standards and learning elements of the dietary life in the 2015 elementary school practical arts, middle and high school 'technology & home economics', and the 'home economics science' curriculum. The results showed that the developed curriculum encompassed additional content beyond all the content already included in the 2015 revised curriculum.
Journal of the Korea Institute of Information and Communication Engineering
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v.7
no.3
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pp.461-467
/
2003
This paper proposes the method of mobility implementation for location searching in the intelligence wireless ATM networks that expand and apply standard broadband signaling capabilities, and analyze the performance based on the numerical algorithm. The existing B-ISDN UNI protocol stack demands the location search mechanism to determine the location of mobile terminal in the wireless ATM networks because it use single protocol through the fixed PTP interface or PTM interface that don't support terminal mobility. The proposed method make possible the dynamic mobility at a part of wireless access by minimizing the signaling load without a falling-off in system performance by using the intelligence network technology according to the expansion of ATM and B-ISDN signaling integration based on the fixed networks. We implemented the performance analysis by MFC modeling based on numerical algorithm, and realized the efficiency of expenses by carrying out the comparative signaling performance evaluation to measure the relative gains of location search service in the intelligence wireless ATM system. The obtained results have the flexibility to operate in the public B-ISDN network environment without a change of existing B-ISDN/ATM NNI signaling reference to support the wireless ATM access system, and can easily expand to correspond to terminal mobility and various multimedia services in the next broadband PCS.
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