• Journal of the Korean Applied Science and Technology
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• v.41 no.1
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• pp.58-68
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• 2024

The purpose of this study was to investigate the effects of treadmill exercise treadmill exercise (TE) and environmental enrichment (EE) interventions on cognitive function, muscle function, and the expression of tight junction proteins in an Alzheimer's disease (AD) animal model. To create the AD animal model, aluminum chloride (AlCl₃) was administered for 90 days (40mg/kg/day), while simultaneously exposing the animals to TE (10-12m/min, 40-60min/day) or EE. The results showed that cognitive impairment and muscle dysfunction induced by AlCl₃ administration were alleviated by TE and EE. Furthermore, TE and EE reduced the increased expression of β-amyloid(Aβ), alpha-synuclein, and tumor necrosis factor-α (TNF-α) proteins observed in AD pathology. Additionally, TE and EE significantly increased the expression of decreased adhesive adjacent proteins (Occludin, Claudin-5, and ZO-1) induced by AlCl₃ administration. Lastly, correlation analysis between Aβ protein and tight junction proteins showed negative correlations (Occludin: r=-0.853, p=0.001; Claudin-5: r=-0.352, p=0.915; ZO-1: r=-0.424, p=0.0390). In conclusion, TE or EE interventions are considered effective exercise methods that partially alleviate pathological features of AD, improving cognitive and muscle function.

• Journal of Korean Ophthalmic Optics Society
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• v.19 no.2
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• pp.153-162
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• 2014

Purpose: This study was assessed to investigate the change of subjective and/or objective symptoms and the light transmittance of lens caused by the use longer than recommended wearing time of daily disposable circle contact lenses (circle lens) in dry eyes. Methods: Three daily disposable circle lenses made of etafilcon A, hilafilcon B, and nelfilcon A were applied on 30 dry eyes with smaller tear volume than normal eyes in their twenties free from any eye diseases by when subjects complained any kind of discomfort. On the first and the last days of lens wearing, subjective discomfort, blinking rate, lens centration on corneal surface and visible light transmittance of lens were recorded at every case and compared. Results: The circle lens wearers complained subjective discomfort and quit the lens wearing when they wore the circle lens longer than 10 hours even though there were some difference according to the lens materials of daily disposable circle lens. However, around 20% of dry eyes could wear the circle lens made of non-ionic materials longer than 40 hours. Dry eyes showed most sensitive feeling of subjective discomfort against the circle lens made of etafilcon A among three different lens materials. On the last day of lens wearing, the representative subjective discomforts were irritation, stiffness, dryness and tiredness. When the subjects wore circle lens more than the recommended time, blinking rate was significantly increased about 20~30% regardless of lens materials when it compared with the values right after lens wearing. On the last day of lens wearing, the vertical direction of lens centration was shifted to pupil center however, its distribution in horizontal direction was wide compared with the distribution right after lens wearing. Especially, the centration of etafilcon A lens was unstable. Furthermore, the visible light transmittance of 3 different circle lenses in dry eyes has significantly been reduced around 15% averaged. Conclusions: From these results, it was known that the increase of dryness and stiffness caused by overusage of daily disposable circle lens induced excess irritation and decreased visible light transmittance and caused significant more blinking, which provoked lens decentration. It was also revealed that dry eyes showed sensitive reaction subjectively and objectively against the overusage of circle lens made of high water content/ionic lens material even there were some difference of the degree depending on the individual and the lens material. Thus, this research can be suggested as the basic reference for the education about some unexpected problems and the side effect caused by the wearing of circle lens in dry eyes.

• Journal of dental hygiene science
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• v.19 no.4
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• pp.245-253
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• 2019

Background: This study aimed to analyze correlations between depression, cognitive function, oral health state, ability to perform activities of daily living, oral dryness symptoms, and oral health-related quality of life, and determine factors influencing the latter. Methods: This was a cross-sectional study based on questionnaires completed by 260 participants with suspected dementia, residing in South Korea. Psychiatrists, psychiatric nurses, and dental hygienists visited clinics in the participating regions for examination and questionnaire administration. General characteristics, the geriatric depression scale, ability to perform activities of daily living, cognitive function, oral health state, and oral health-related quality of life were analyzed. Independent t-tests, one-way analysis of variance (ANOVA), correlation analysis and multiple regression analysis were conducted, identifying factors affecting oral health-related quality of life. Data analysis was performed using SPSS ver. 20.0 (IBM Corp., USA), and the significance was set at p<0.05. Results: Approximately 65.0% of participants were female, 63.5% were in their 70s, and 90.0% had health insurance. About 21.5%, 42.0%, and 36.5% were normal, slightly impaired, and had dementia, respectively. High cognitive impairment was associated with poor oral health. Sex, education levels, marital status, and living arrangements influenced oral health-related quality of life. According to the regression analysis, geriatric depression and oral dryness affected the Geriatric Oral Health Assessment Index scores. Conclusion: In conclusion, oral dryness and depression levels among elders influenced oral health-related quality of life. The results showed that to enhance elders' oral health-related quality of life, it is essential to not only improve their oral health state, but also relieve oral health problems, especially oral dryness, and take into consideration their psychological aspects.

• Korean Journal of Food Science and Technology
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• v.39 no.2
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• pp.109-113
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• 2007

Adenophora remotiflora (Mosidae) is a perennial plant in the Campanulaceae family and a wild plant that only inhabits in Korea. This research analyzed the volatile compounds in Mosidae and their antioxidant activities. The volatile compounds in fresh, shady air-dried, and freeze-dried Mosidae were isolated by steam-distillation extraction (SDE) method using diethylether as a solvent. Volatile compounds were analyzed by gas chromatography-mass spectrometry (GC/MS). Antioxidant activities were determined using the linoleic acid system and 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. Sixty and seventy-two volatile compounds were identified from fresh and shady air-dried Mosidae, respectively. In fresh Mosidae, the most abundant compounds were ethyl acetate and heptyl acetate, while ethyl acetate and limonene were the most abundant in the shady air-dried sample. Inhibition of peroxide formation by fresh Mosidae was higher than that of ${\alpha}-tocopherol$, and inhibition by shady air-dried Mosidae was same as that of ${\alpha}-tocopherol$. Furthermore, volatile compounds from shady air-dried Mosidae had higher free radical scavenging activity than ${\alpha}-tocopherol$. The freeze-dried sample showed lower antioxidant activity in both the linoleic acid system and DPPH method.

• Journal of Technologic Dentistry
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• v.36 no.4
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• pp.277-296
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• 2014

Purpose: This study intends to set standard for organizing the curriculum of short-term dental technicians and the change of job environment, as well as the knowledge & training, by identifying the importance and actual job performance of dental technicians following job analysis in the university education of Dept. of Dental Laboratory Technology, and furthermore to foster junior executives to cope with modernization and globalization. Methods: The tools used in this study are based on the job analysis of research report suggested by National Health Personnel Licensing Examination Board(Lee Gyu-seon, 2011), and it consists of general characteristic 7 items. Every competence duty was measured through Likert 5 point gauging, and internal consistency through Cronbach's Alpha. The competence importance of entire questionnaire was .984 and its performance was .874, reflecting considerably high level, and in terms of each competence duty, high credibility was proved and high internal consistency was verified with competence importance ranging from the minimum .655 to the maximum .966 and its performance ranging from the minimum .677 to the maximum .993. Results: Competence importance and its performance in each duty on the job analysis of dental technicians were measured. In competence importance in each duty, the highest was "checking design order form"(average, 4.52), followed by "selling dental prosthesis"(average 4.49), "making removable orthodontic appliance"(average, 4.48), "open managing dental laboratory"(average, 4.46) in order. However, "making complete denture" was found the lowest(average, 4.23), with importance of all competence dutys was considerably high level. In the performance of its competence duty, "checking design order form"(average, 4.04) was found to be the most importance competence, followed by "making conservative restoration"(average, 4.00), "making porcelain"(average 3.98), "checking working cast"(average, 3.90) in order. However it was found out that "making fixed orthodontic appliance"(average, 3.12) was the lowest, and the importance of all competence dutys was quite high level. Conclusion: The duties of dental technicians consist of 13 kinds, in total, and it was found out that "checking design order form"(average, 4.52) was the most important in the competence importance and job performance. In particular, it was revealed that there was a great difference between the competence importance and its performance in the order of "selling dental prosthesis", "open managing dental laboratory", "making removable orthodontic appliance", "making CAD/CAM prosthesis", and then "making fixed orthodontic appliance".

• International Commerce and Information Review
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• v.14 no.2
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• pp.411-443
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• 2012

The Changes in management environment in SMEs such as rapid development of information communication technology, worldwide expansion of FTAs, enlargement of global outsourcing, etc have changed various aspects in industry-academy or industry-academy-government cooperation. It has been away from the cooperation focused on research and development and industrial training, and advanced to the cooperation focused on the business fields and practices where the executive ability and professionalism are required to commercialize major products of local SMEs. Compared with the existing model, the new model of industry-academy-government cooperation can provide effective and customized supports to local SMEs and expect better performance than ever before through the choice and focus. However, the existing support programs of government and related organizations are just top-down pattern to SMEs. In addition to the development of industrial technology, education and training for labor force and knowledge interchange between industry and university, the new cooperation model would also provide practical tasks such as enhancement of business competences and abilities to cultivate foreign markets. This study deals with Gyeongbuk PRIDE Products support project that is the new model of industry-academy-government cooperation and evaluates the effectiveness of this support project by empirically analyzing the survey results from the target SMEs.

• Korean Journal of Food Science and Technology
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• v.32 no.2
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• pp.231-237
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• 2000

A Comparative study was performed among five Korean wheat(Greu, Eunpa, Tapdong, Allgreu, Woori) and three imported wheat(Dark Northern Spring, Austrian Standard Wheat, Western White) to investigate the characteristics of minerals and phytate from Korean wheat varieties. Ash contents of kernel was higher in Korean wheat than in imported wheat and related to ash contents and darkness of flour. More contents of Fe, P, and Mg from Korean wheat grains and Fe from Korean wheat flours were observed in comparison to imported wheat varieties. Fe concentration in Korean flour show high, indicating Fe was distributed at endosperm layer of kernels and not eliminated with milling. In addition, phytate affecting availability of minerals was determined from kernels and flours. Even though Korean wheat kernels had more phytate than that of imported wheat kernels, it is believed that most of phytate was removed with milling and there was no major difference between Korean and imported wheat flours. We also observed that the content of phosphate closely parallels the content of phytate from both the flours and kernels.

• The Journal of the Convergence on Culture Technology
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• v.5 no.2
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• pp.123-138
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• 2019

The clinical institution of some dental hygiene students and the degree of practice and performance according to the practice contents are identified, so as to develop clinical practice guidelines and to improve the education of universities and practical institutions. From November 2016 to March 2017, the questionnaire was prepared by self-inclusion after explaining the purpose of research and how to prepare questionnaire to some dental hygiene students. This material has been analyzed using PASW Statistics 18.0. As for the clinical practice content items of basic care and infection control, the frequency of "execution" among practice methods was high, and the distribution rate was high in oral evil face radiation, preventive dentistry, prosthesis, periodontology, orthodontics, and oral internal medicine. The conservation department has conducted various practical methods such as "executing," "observing" and "preparing." Oral surgery showed similar distribution rates, such as "observation," "preparation," and "execution" in the "preparation and cooperation of the feet." In pediatric dentistry, "observation" was the most common practice, and among them, "observation," "preparation," and "execution" were performed in "preparation and cooperation for infantile development." In addition, students with more experience in clinical practice showed statistically significant differences in basic care, oral hygiene, preventative dentistry, conservation, dental dentistry, oral surgery, orthodontics, and oral internal medicine(p<0.05). Most clinical practice shows that it is more observable than performed.It is expected that the goal of clear clinical practice content should be set by grade or number of clinical practice experiences, as well as the practice method that can be performed by the trainees.

• Journal of Species Research
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• v.12 no.1
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• pp.68-89
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• 2023

This is the second catalog listing unrecorded invertebrates discovered during the research project 'Discovery of Korean Indigenous Species'. The data to compile the catalog were primarily gathered from the final reports of the project, between 2013 and 2021. We present 38 previously undocumented species, belonging to four phyla (Platyhelminthes, Annelida, Rotifera and Arthropoda). Samples were collected from intertidal coastal waters, soil, freshwater ponds, reservoirs and hosts in South Korea. In this study, we provide brief taxonomic information, including collection site (GPS), diagnosis, specimen vouchers, figures of representative individuals and the Korean name newly assigned, for each species. All data were reviewed and updated by experts working on the respective taxonomic group. The aim of the present study is to publish species that have been previously reported through the project. Upon publication, these species will be added to the 'National Species List of Korea', curated by the National Institute of Biological Resources(NIBR).

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.16 no.6
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• pp.441-447
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• 2023

Intravenous infusion therapy is a standard nursing procedure in medical institutions that provides patients with drugs, fluids, blood, and nutrients into the patient's mucus. It is mainly performed and managed by nurses. Additionally, it is an injection method that injects drugs directly into the blood vessels, and is used to achieve rapid results in emergency situations, and quick and accurate effects can be expected. Even experienced nurses through education and training often make mistakes, which can not only cause discomfort to patients but also cause various problems that threaten patient safety. Various studies are being conducted to reduce the pain caused by these mistakes. This paper acquired images of veins on the back of the hands of three subjects through an image detection device and conducted a study to derive an algorithm to provide clear vein images through image processing of the collected images. To sharpen the acquired vein images, existing algorithms Histogram Equalization, CLAHE, and Unsharp Masking were selected and combined. A histogram graph was used to compare images derived by applying individual algorithms and algorithm combinations to images. The histogram graph was checked by calculating the difference between the minimum and maximum values of distributed pixels and averaging them. The algorithm combination presented in this paper was 209.1, which was higher than the average values of individual algorithms of 138.7, 132.3, and 126.2, and it was confirmed that visibility was good even in actual images.