• Journal of Biosystems Engineering
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• v.38 no.2
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• pp.163-170
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• 2013

Purpose: The purpose of this study is to provide analysis of physiological, biomechanical responses occurring from the operation to lifting or twist lifting task appears frequently in agricultural work. Methods: This study investigated the changes of physiological factors such as heart rate, heart rate variability (HRV) and biomechanical factors such as physical activity and kinetic analysis in the task of twisting at the waist while lifting. Results: Heart rates changed significantly with the workload. The result indicated that the workload of 2 kg was light intensity work, and the workload of 12 kg was hard intensity work. Physical activity increased as the workload increased both on wrist and waist. Besides, stress index of the worker increased with the workload. Dynamic load to herniated discs was analyzed using inertial sensor, and the angular acceleration and torque increased with the workload. The proposed measurement system can measure the recipient's physiological and physical signals in real-time and analyzed 3-dimensionally according to the variety of work load. Conclusions: The system we propose will be a new method to measure agricultural workers' multi-dimensional signals and analyze various farming tasks.

• Journal of Microbiology and Biotechnology
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• v.32 no.2
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• pp.228-237
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• 2022

In this study, the effects of the immune stimulator Euglena gracilis (Euglena) in cyclophosphamide (CCP)-induced immunocompromised mice were assessed. The key component β-1,3-glucan (paramylon) constitutes 50% of E. gracilis. Mice were orally administered Euglena powder (250 and 500 mg/kg body weight (B.W.)) or β-glucan powder (250 mg/kg B.W.) for 19 days. In a preliminary immunology experiment, ICR mice were intraperitoneally injected with 80 mg of CCP/kg B.W. during the final 3 consecutive days. In the main experiment, BALB/c mice were treated with CCP for the final 5 days. To evaluate the enhancing effects of Euglena on the immune system, mouse B.W., the spleen index, natural killer (NK) cell activity and mRNA expression in splenocytes lungs and livers were determined. To detect cytokine and receptor expression, splenocytes were treated with 5 ㎍/ml concanavalin A or 1 ㎍/ml lipopolysaccharide. The B.W. and spleen index were significantly increased and NK cell activity was slightly enhanced in all the experimental groups compared to the CCP-only group. In splenocytes, the gene expression levels of tumor necrosis factor-α, interferon-γ, interleukin (IL)-10, IL-6, and IL-12 receptor were increased in the E. gracilis and β-glucan groups compared to the CCP-only group, but there was no significant difference. Treatment with 500 mg of Euglena/kg B.W. significantly upregulated dectin-1 mRNA expression in the lung and liver compared to the CCP-only group. These results suggest that Euglena may enhance the immune system by strengthening innate immunity through immunosuppression.

• Food Science and Preservation
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• v.15 no.2
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• pp.269-273
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• 2008

In this study, we investigated changes of general components and biological activity of the fruit of Prunus mume. The average moisture content of the fruit ranged from 88.34-90.04%. Crude protein and crude fat contents were not significantly different among samples. During ripening, crude protein decreased and crude fat increased. The level of polyphenols in the fruit gradually increased during ripening. An antimicrobial activity test indicated that methanol extracts had the highest activity and that the antimicrobial activity increased gradually with harvest time. Antimicrobial substances in methanol extracts of the fruit maintained their activity after heating at $100^{\circ}C$ for 30 minutes and were unaffected by changes in pH. The antioxidant activities of extracts isolated with different solvents were: methanol> ethylacetate > water> ether> hexane. Antioxidant activity was not significantly different for different harvest times. The antioxidant index of the methanol extract was also the highest in electron donating activity.

• KSBB Journal
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• v.30 no.4
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• pp.155-160
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• 2015

The present study was to investigate the antioxidant activity in ethanol and water extracts of root and stem of Sargassum coreanum. Antioxidant activities were evaluated by total polyphenol contents, DPPH radical scavenging activity, chelating effect, reducing power, and rancimat method. Total polyphenol contents of ethanol and water extracts were 32.79 mg/g and 15.55 mg/g, respectively. Ethanol extract showed higher DPPH radical scavenging activity than water extract and similar activity to BHT. Reducing power of extracts was increased in a concentration-dependent manner and ethanol extract had more reducing power than water extract. Ethanol and water extracts have little chelating effect at all concentrations. Antioxidant index (AI) of ethanol extract measured by Rancimat was higher than that of water extract, but their AI was lower than that of BHT. These results indicate that ethanol extract of S. coreanum root and stem has more potent antioxidant activity than water extract through DPPH radical scavenging and reducing power, and could potentially be used as a good source of natural antioxidants.

• Journal of Veterinary Science
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• v.24 no.3
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• pp.44.1-44.17
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• 2023

Background: Antibiotic resistance is a significant public health concern around the globe. Antimicrobial peptides exhibit broad-spectrum and efficient antibacterial activity with an added advantage of low drug resistance. The higher water content and 3D network structure of the hydrogels are beneficial for maintaining antimicrobial peptide activity and help to prevent degradation. The antimicrobial peptide released from hydrogels also hasten the local wound healing by promoting epithelial tissue regeneration and granulation tissue formation. Objective: This study aimed at developing sodium alginate based hydrogel loaded with a novel antimicrobial peptide Chol-37(F34-R) and to investigate the characteristics in vitro and in vivo as an alternative antibacterial wound dressing to treat infectious wounds. Methods: Hydrogels were developed and optimized by varying the concentrations of crosslinkers and subjected to various characterization tests like cross-sectional morphology, swelling index, percent water contents, water retention ratio, drug release and antibacterial activity in vitro, and Pseudomonas aeruginosa infected wound mice model in vivo. Results: The results indicated that the hydrogel C proved superior in terms of cross-sectional morphology having uniformly sized interconnected pores, a good swelling index, with the capacity to retain a higher quantity of water. Furthermore, the optimized hydrogel has been found to exert a significant antimicrobial activity against bacteria and was also found to prevent bacterial infiltration into the wound site due to forming an impermeable barrier between the wound bed and external environment. The optimized hydrogel was found to significantly hasten skin regeneration in animal models when compared to other treatments in addition to strong inhibitory effect on the release of pro-inflammatory cytokines (interleukin-1β and tumor necrosis factor-α). Conclusions: Our results suggest that sodium alginate -based hydrogels loaded with Chol-37(F34-R) hold the potential to be used as an alternative to conventional antibiotics in treating infectious skin wounds.

• Science of Emotion and Sensibility
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• v.9 no.4
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• pp.353-366
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• 2006

The aim of this study is to characterize the optical properties of white light-emitting diodes lighting modules and then to evaluate the sensitivity of students and teachers in reacting to the optical properties of these modules. For the sake of this study, each of 5 lighting modules was introduced to the 5 test cabinets. The 5 test cabinets were evaluated and analyzed the student and teacher's sensitivity reaction. We have selected If questions on sensitivity of the lighting and evaluated these questions with semantic differential method. To verify the reliability and objectivity of the questions, the feasibility survey was carried out by a preliminary test. As a result of the test, the sensitivities on the test cabinets were classified the 4 factors, namely, activity as the first factor, stability as the second one , potency as the third one and sensitive image as the fourth one respectively. By the evaluation of student and teacher's sensitivity on the correlated color temperature, they preferred the cabinet with the higher color temperature in view of the activity and potency. And they preferred the cabinet with the lower color temperature in view of the stability factor. In the sensitive image, they preferred the 5800K, bluish white lighting regardless of the color temperature. By the evaluation on the color rendering index, they preferred the cabinet with the higher color rendering index in view of the activity, stability and sensitive image. In the potency factor, they preferred the white lighting with the middle color rendering index.

• Food Science and Biotechnology
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• v.18 no.6
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• pp.1481-1486
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• 2009

The immunomodulating effect of Salicornia herbacea polysaccharides on BALB/c mice splenocytes was investigated. Crude (CS) and fine polysaccharide (PS) extracts with potential biological activity were prepared from S. herbacea. For in vitro experiments, splenocytes and separated T cells were treated with CS and PS (0.5, 1, 2, and 4 mg/mL). For in vivo experiments, the CS and PS were orally administered to BALB/c mice every day for 2 weeks. For basic data analysis, physiological parameters were recorded. Cell proliferation of splenocytes and T cells was used as an index for immunomodulating activity. The proliferation of splenocytes and separated T cells was 3.2 and 3.5 times higher than the control, respectively. Moreover, when splenocytes were treated with mitogen, the highest proliferation rate was observed in splenocytes cultured with PS. Interestingly, the stimulative activity of PS was more strongly exerted through $CD4^+$ T cells than through $CD8^+$ T cells.

• The Journal of Asian Finance, Economics and Business
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• v.5 no.1
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• pp.43-52
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• 2018

This research aims to evaluate the current state of technology of enterprises in Vietnam in comparison with several countries in the AEC economic community, thereby to propose several recommendations to Vietnamese enterprises in order able to promote technology innovation activities, create competitiveness with enterprises in the region. Qualitative research methods are used through statistics and comparative descriptions from data collected from various sources: WEF, World Bank, CIEM, General Statistic Office. The study results show that Vietnamese enterprises still have many limitations in technology, originated from their small business scale (capital and labor), the current research capacity is still low, the funding for this activity is not high and the accessibility of the capital is still difficult. According to the Global Competitiveness Index, Vietnam's science and technology indexes are low compared to other AEC-developed countries including the availability of the latest technology; the acquisition of technology at the enterprise level; the capacity of improvement; quality of scientific research organizations..., which shall be a major barrier for Vietnamese enterprises to have to overcome to be able to create the competitiveness when entering the global market. From then on, the authors proposed solutions for two subjects, enterprises and government, to help Vietnamese enterprises to overcome this barrier.

• Korean Journal of Food Science and Technology
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• v.24 no.2
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• pp.142-148
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• 1992

Certain parts of 95 species of edible and medical plants were extracted with water and 75% of ethyl alcohol. After addition of those extracts to palm oil, lard and soybean oil at different level, their antioxidative activities were compared by Rancimat test. Six species among them seemed to have rather strong antioxidative activity and high extracting yields(i.e. Taraxacum platycarpum, Plantago asiatica, Rhus javanica L., Lycopus lucidus, Astragalus membranaceus, Taraxacum platycarpumH). Among them, the Rhus javanica L. ethanol extract retarded greatly the induction period of palm oil and lard. When 600 ppm of Rhus javanica L. extract were added to palm oil and lard, AI(antioxidant index was expressed as induction period of oil containing various plant extracts/induction period of control oil) of each was 1.35 and 3.03 respectively. This result indicated that the Rhus javanica L. extract was more effective on lard than the other oils.

• Informatization Policy
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• v.29 no.4
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• pp.43-66
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• 2022

With the development of artificial intelligence technology, competition for artificial intelligence technology patents around the world is intensifying. During the period 2000 ~ 2021, artificial intelligence technology patent applications at the US Patent and Trademark Office have been steadily increasing, and the growth rate has been steeper since the 2010s. As a result of analyzing Korea's artificial intelligence technology competitiveness through patent indices, it is evaluated that patent activity, impact, and marketability are superior in areas such as auditory intelligence and visual intelligence. However, compared to other countries, overall Korea's artificial intelligence technology patents are good in terms of activity and marketability, but somewhat inferior in technological impact. While noise canceling and voice recognition have recently decreased as topics for artificial intelligence, growth is expected in areas such as model learning optimization, smart sensors, and autonomous driving. In the case of Korea, efforts are required as there is a slight lack of patent applications in areas such as fraud detection/security and medical vision learning.