• Polymer(Korea)
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• v.33 no.3
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• pp.219-223
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• 2009

The nanofibers fabricated by using an electrohydrodynamic process has been used as various applications, such as nano-device, filtering system, protective clothes, wound dressing, and drug delivery system (DDS). Of these applications, the DDS should be needed to minimize side effects of drugs, maximize the properties of medicine, and efficiently deliver the required amount of drugs to the diseased area. In this paper, by using the electro spinning process, which is one of electrohydrodynamic processes, two different types, polycarprolactone and poly(ethylene oxide)/Rhodamine B, of electrospun mats were fabricated layer by layer and the release behavior of Rhodamine B was characterized with time. In addition, to show the feasibility of DDS of this type, we tested release behavior of a peptide of the nanofiber system, a PCL/(Peptide+PEO)/PCL nanofiber mat. The released peptide did not loss biological activities. From these results, we believe that the layered nanofiber mat as a DDS has enough function of a new drug delivery system.

• Physical Therapy Korea
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• v.18 no.1
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• pp.74-82
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• 2011

The purpose of this study was to compare the anaerobic threshold (AT) between subjects with and without non-specific chronic low back pain (NCLBP). The patient group included 15 women with NCLBP. The normal group included 15 women without NCLBP who were age-, height-, weight-, and activity level-matched. The subjects performed a Balke treadmill protocol which was symptom-limited progressive loading test. Their heart rate (HR), ventilatory gas and metabolic equivalents (METs) were measured using the automatic breath gas analyzing system. After the test, each subjects' ratings of perceived exertion (RPE) were evaluated. The visual analog scale (VAS) was assessed pre- and post-test. The independent t-test and Wilcoxon's signed-rank test were used for analysis of the data. Time, HR, the volume of oxygen consumption ($VO_2$), relative $VO_2$, and METs at the AT level of the patient group were significantly lower than those of the healthy group (p<.05). However, there were no significant differences in RPE, VAS, and breathing frequency at the AT level (p>.05). The findings of this study indicate that patients with NCLBP had a lower aerobic fitness than healthy subjects. Thus, implementation of rehabilitation program to increase aerobic fitness may be considered in patietns with NCLBP, and further studies are required to determine the etiological factors of decreased aerobic fitness.

• Research in Community and Public Health Nursing
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• v.15 no.4
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• pp.539-550
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• 2004

Purpose: The purpose of this study was to evaluate the achievements of the project, and also to find out its strengths and weaknesses. Method: This evaluative study employed system theory and analytic techniques by using criteria which were relevance, appropriateness, adequacy, progress, effectiveness and satisfaction for input, process, output, and outcome of program. Study subjects were participants in the home health care program implemented in G public health center in Inchon metropolitan city in 2003. Results: Input factors including recruitment personnel, and support organization development were not adequately met for the program. However. the goal and objectives of the project were really appropriate for the community needs as well as government's policy. For the Process evaluation, home health care record form and computer data base had not progressed as scheduled, but overall program activities were finished on time. However, cooperation between organizations in the health center during service activity were not supportive. Managerial ability of program charged personnel about coordination and integration of team members was not affirmative. Output and outcome evaluation showed that people improved self care ability were 221 (17.5%). and 71 (5.62%) of subjects were moved into category of possible self-care. Client's satisfaction for this project showed a high degree. Conclusions: Based on the above results support organization and staff personnel for this program should be developed. Also, a community network of resources should be established and case management services should be focused continuously in community based home health care.

• Journal of The Korea Institute of Healthcare Architecture
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• v.23 no.3
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• pp.29-37
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• 2017

Purpose : Due to the shortage of the room for the disabled, it may be difficult to use the accommodation for the disabled (especially wheelchair users). The purpose of this paper is to propose a universal design(UD) application for all rooms to solve the problems caused by the shortage and the decrease of the usage rate of the rooms for the disabled. Methods : Classify and analyze the type of room and bathroom according to the survey. The space of the room is classified into six types mainly based on the relation and location among the entrance, the bathroom, and the bedroom. Also, the bathroom is classified into 20 types considering the positional relationship with the entrance and between sanitary fixture. By using these types, FGI survey will be conducted and the application of UD will be reviewed and presented. Results : We analyzed by using the types of the room and the bathroom. One of majority type in the actual research and two of UD applicable types from FGI, are shown UD application. In addition, the bathroom were analyzed about four types from FGI. The room were shown about the activity space and the furniture layout for UD. The bathroom were shown about the space for the entrance, the internal activitiy space and the arrangement of the sanitary fixture. Implications : By comparing and analyzing through type classification, it was found that universal design can be applied to all rooms. Therefore, it is expected that the UD will be activated in all rooms of the accommodation.

• Journal of Practical Engineering Education
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• v.8 no.1
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• pp.1-7
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• 2016

In this paper, the proceedings and core procedures that involved the role of advisor to the theme, the set up rule of students, and complete the work steps involved in configuring graduate work that the overall design curriculum and graduation standards are summarized. The one or two students are designated as one team, and by the designated professor was conducted a discussion and technical guidance. Among various topics from 2011 to 2015, some specific results configured using a small drone and smartphones are presented. The survey are compared the activity results for the participating students in one major each in 2011 and 2015 and analyzed. Based on this review for improvement next year notes, it forms a continuous improvement, and has converged talents with passion and challenging spirit, sharing a plan to form a virtuous cycle that is associated with positive employment and entrepreneurship.

• Environmental Engineering Research
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• v.13 no.3
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• pp.155-161
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• 2008

This study examined effects of the fermented leachate of food waste (FLFW) on nitrogen and phosphorous removal for domestic wastewater containing a low carbon-to-nitrogen (C/N) ratio in sequencing batch reactor (SBR). When the FLFW was not supplied in the process, release of phosphorus and excessive intake was not observed at both anaerobic and aerobic stages. On the other hand, when the FLFW was gradually added, active release of phosphorus and intake of phosphorus was noticed at an anaerobic stage and aerobic stage, respectively, resulting in improved phosphorus removal efficiency. The removal efficiency of nitrogen and phosphorus was increased from 75% and 37% (R-1, control test) to 97% and 80% (R-4, the highest substrate ratio test), respectively. In addition, although activity of the nitrogen oxidizing microorganisms was reduced when the reaction temperature was decreased to $10^{\circ}C$, the phosphorus removal efficiency was shown to increase with the addition of FLFW, indicating an independence from temperature. Overall, this study suggests that an efficient nutrients removal process can be successfully employed into a SBR when the FLFW is added to a wastewater which has a low C/N ratio.

• Proceedings of the Korea Contents Association Conference
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• 2008.05a
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• pp.732-737
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• 2008

As e-learning is recognized in new education form, Learning Management System that manage general activity of learning to maximize effect of education is being developed actively. Usually, Learning Management System includes course registration and learning as well as learner's learning recording and tracking, evaluation in online. But, most systems is lacking a tool that learners can collaborate with companion learners, and planning learning and set valuation basis as leading. In this paper, we can expect effective collaborative learning activities because can make debate and team project smooth by suggesting collaborative learning module that can drive voluntary participation such as group formation, learning plan, mutually estimation as leading to learner in Learning Management System of blended learning base that support online and offline environment both.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.3
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• pp.721-727
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• 2007

Scorpion (SCP) has been clinically used for the treatment of endogenous wind to relieve convulsion, clearing away toxins, resolving hard masses and removing obstruction in the collaterals to relieve pain. Recent studies showed that scorpion toxins that affect the activating mechanism of sodium channels and indian black scorpion venom induced anti-proliferative and apoptogenic activity against human leukemic cell lines U937 and K562. There is lack of studies regarding the effects of SCP on the immunological activities. The present study was conducted to evaluate the effect of SCP on the regulatory effects of cytokines and nitric oxide (NO) for the immunological activities in Raw 264.7 cells. After the treatment of SCP MeOH extract dissolved in media for 1 h prior to the addition of lipopolysaccharide (LPS: 1 ${\mu}$g/ml), cell viability was measured by MTT assay, NO production was monitored by measuring the nitrite content in culture medium. Inducible nitric oxide synthase (iNOS) was determined by immunoblot analysis, and levels of cytokine were analyzed by sandwich immunoassays. As results, SCP inhibited the production of nitrite and nitrate (0.3 and 1.0 mg/ml), iNOS and p-$I_KB_{\alpha}$ protein, tumor necrosis factor-${\alpha}$ (0.3 and 1.0 mg/ml), interleukin-1${\beta}$ (0.3 and 1.0 mg/ml) and interleukin-6 (1.0mg/ml) in Raw 264.7 cells activated with LPS. These findings suggest that SCP can produce anti-inflammatory effect, which may play a role in adjunctive therapy in Gram-negative bacterial infections.

• Toxicological Research
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• v.28 no.4
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• pp.241-248
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• 2012

Exposure of cells to ultraviolet B (UVB) radiation can induce production of free radicals and reactive oxygen species (ROS), which damage cellular components. In addition, these agents can stimulate the expression of matrix metalloproteinase (MMP) and decrease collagen synthesis in human skin cells. In this study, we examined the anti-photoaging effects of extracts of Tetraselmis suecica (W-TS). W-TS showed the strongest scavenging activity against 2,2-difenyl-1-picrylhydrazyl (DPPH) and peroxyl radicals, followed by superoxide anions from the xanthine/xanthine oxidase system. We observed that the levels of both intracellular ROS and lipid peroxidation significantly increased in UVB-irradiated human skin fibroblast cells. Furthermore, the activities of enzymatic antioxidants (e.g., superoxide dismutase) and the levels of non-enzymatic antioxidants (e.g., glutathione) significantly decreased in cells. However, W-TS pretreatment, at the maximum tested concentration, significantly decreased intracellular ROS and malondialdehyde (MDA) levels, and increased superoxide dismutase and glutathione levels in the cells. At this same concentration, W-TS did not show cytotoxicity. Type 1 procollagen and MMP-1 released were quantified using RT-PCR techniques. The results showed that W-TS protected type 1 procollagen against UVB-induced depletion in fibroblast cells in a dose-dependent manner via inhibition of UVB-induced MMP-1. Taken together, the results of the study suggest that W-TS effectively inhibits UVB-induced photoaging in skin fibroblasts by its strong anti-oxidant ability.

• Journal of The Korean Association of Information Education
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• v.23 no.1
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• pp.55-64
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• 2019

Recently, entrepreneurship education has been emphasized in order to bring creative innovation to the fourth industrial revolution era. The purpose of this study is to suggest methods to promote practice by developing an educational program based on the maker education model to foster entrepreneurship of adolescents proposed in the previous study. For this purpose, we developed two kinds of programs and materials according to the subject and the level for the 3rd grader in middle school and first grader in high school. The final output was composed of the workbook for students, the guidebook for teachers, the PPT, and the worksheet for a team activity. The pilot workshop of the developed program was conducted for 14 middle school students. The final program was developed after being received advisories by three experts. This study is meaningful in that it can contribute to foster entrepreneurship education in the field by proposing specific programs required for practicing maker education for entrepreneurship.