• 한국임상수의학회지
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• 제26권5호
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• pp.486-489
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• 2009

An 8-year-old Thoroughbred mare showing anestrus for longer than 6 months with left ovarian mass was referred to Veterinary Medical Teaching Hospital of Seoul National University. For 6 months, the mare had received 2 times hormonal therapies with $PGF_2{\alpha}$ and progesterone. The mare had not responded to these therapies and not shown estrous behavior. On rectal palpation, the left ovary was enlarged and contralateral ovary was small and inactive. Transrectal ultrasonographic examination of the left ovary revealed a mass composed of multiple, irregularly shaped follicles. Granulosa cell tumor (GCT) was suspected according to her history. Ovariectomy was performed through the left flank laparotomy with a standing position in a simple chute located outside of horse farm. The mass was diagnosed as GCT on histopathology. The mare was recovered without any problem and became pregnant next spring.

• 한국임상수의학회지
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• 제33권6호
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• pp.392-394
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• 2016

A 2-year-old spayed female Persian cat presented to Kangwon National University Veterinary Medical Teaching Hospital with pruritus and erythema on the tips of both ears, around the eyes, and in the caudal abdomen. This patient had previously been prescribed prednisolone, but did not respond positively to the treatment. A skin screening test revealed that there were no fleas or fungi, and that only cocci were present. Blood testing revealed no remarkable findings. The patient was prescribed antibiotics (amoxicillin-clavulanic acid 25 mg/kg for 2 weeks) with no prednisolone. After 2 weeks, clinical signs were alleviated and the skin screening test showed no signs of cocci. However, clinical signs recurred even with the prescription of antibiotics. Four weeks after the steroid-free interval, Malassezia spp. hypersensitivity was detected upon a serum allergy test, and pathological analysis confirmed eosinophilic and mastocytic superficial dermatitis in the caudal abdomen. Based on these results, we suspected allergic dermatitis and prescribed 7 mg/kg cyclosporine A once a day. After 3 weeks, clinical signs were resolved. Seven weeks after the first trial with cyclosporine A, we reduced the cyclosporine A dose to 7 mg/kg every other day. The patient's symptoms have since been well controlled for 6 months. This study suggests that cyclosporine A can be a good choice for treating cats with suspected allergic dermatitis that has not responded positively to steroid treatment.

• Parasites, Hosts and Diseases
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• 제36권2호
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• pp.147-150
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• 1998

국내에서 사육되고 있는 개의 와포자충 감염 실태를 알아보기 위하여 1996년 1월부터 1997년 11월까지 4개 지역 (강원도 춘천, 경상남도 상주, 경기도 과천 및 성남)의 개 257두의 분변을 수집하였다 와고자충의 확인은 현재 상품화되어 판매되고 있는 CrHptosporidium 진단 킷트 (MeridianDiagnostics. Cincinnati. Ohio)를 사용하였다. 총 257두 중 25두에서 와포자충 오시스트가 확인되어 9.7%의 검출률윽 나타내었는데, 과천지역이 17 2%로 가장 높았고, 춘천지역 13.2%, 성남지역이 1.4%인 반면, 상주지역은 오시스트가 검출되지 않았다. 개의 사육형태별 검춘률은 사랍과 함께 생확하는 실내견이 13.9%로 가장 높았고, 집지키는 개가 10.1%, 그리고 잡견 (또는 사육견)이 6. 1%로 밝혀졌다. 이상의 결과로 보아 국내에 있는 여러 종류의 사육견들이 와포자충에 감염되어 있음을 화인할 수 있었으며, 특히 사람과 함께 생활하는 애완견에서 감염률이 높다는 사실은 환경의 오염에 의하여 애발견에서 사람으로 와포자충의 전파가 가능할 수도 있다는 점을 시사하는 것으로 이에 대한 대책이 필요할 것으로 생각된다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제23권4호
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• pp.397-404
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• 2020

Purpose: Synbiotics can alleviate some intestinal pathologies or prevent trigger mechanisms for some diseases such as celiac disease (CD). If patients with high levels of anti-tissue transglutaminase (anti-tTG) immunoglobulin A (IgA) antibodies have normal duodenal histology, they are followed as potential CD patients. The aim of this study was to investigate the effect of synbiotic use on the blood levels of anti-tTG antibodies in children. Methods: Eighty-two patients with high anti-tTG levels were included in this study. Patients were randomly divided into two groups. The synbiotic group was treated with a daily dose of a synbiotic including multi-strain probiotics for 20 days. The control group was not administered any medication. Anti-tTG values at baseline and repeat measurements and the percentage change in anti-tTG levels between groups were compared. Results: The anti-tTG level at baseline was 36 U/mL (interquartile range [IQR], 26.4-68 U/mL) in the synbiotic group, and it decreased significantly to 13 U/mL (IQR, 6.5-27.5 U/mL) after 20 days (p<0.05). The anti-tTG level at baseline was 46 U/mL (IQR, 31-89 U/mL) in the control group, which also decreased significantly to 23 U/mL (IQR, 7-41 U/mL) after 20 days (p<0.05). Anti-tTG levels exhibited 73% and 56% decreases in the synbiotic and control groups, respectively (p<0.05). Conclusion: It may be speculated that a synbiotic supplementation can contribute to decreasing anti-tTG levels in children with potential CD.

• 대한수의학회지
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• 제39권4호
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• pp.838-845
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• 1999

To determine the prognostic factors for survival of dogs infected with canine parvovirus, clinical and laboratory data of 35 dogs with clinical signs compatible with canine parvoviral enteritis admitted to the Veterinary Medical Teaching Hospital, Seoul National University during the period 1997-1998 were collected. Dogs were grouped by some major covariates, which can be considered as guides to the relative prognosis of dogs in the different subgroups. The Kaplan-Meier survival analysis and Weibull proportional hazard model were used to estimate overall survival, evaluate the comparability between groups, and identify potential prognostic factors. The overall survival rate for all dogs was 45.7% over the study period, and the Kaplan-Meier estimate of one week survival was 0.4989. Gender was the most favorable prognosis ; male dog (median, 6 days) had significantly higher risk of dying than female dog (median, 17 days ; p = 0.0023). In addition to gender, age was significantly associated with survival, with juvenile dogs less than 6-month-old having higher risk (p = 0.0359). Dogs that vaccinated with complete protocol (p = 0.0374) and those of having higher value of mean corpuscular volume (p = 0.0346) were found to be of prognostic importance. The 7 dogs in which white blood cell count of less than 2000 had shorter median survival time (3 days) than the remaining 28 dogs (8 days), but no statistical significance was found between leukopenic and survival. The distribution of packed cell volume and hemoglobin measurement was such that the overall risk of dying in the two groups was comparable. Further studies are needed to more accurately assess these results.

• 한국수정란이식학회지
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• 제23권2호
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• pp.119-125
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• 2008

A 3-month-old American Cocker spaniel was presented at the Veterinary Teaching Hospital, Chungbuk National University, for examination of urinary tract after dissection of vaginal mass at local clinic before 10 days. Clinical examination of the affected bitch revealed a normal sized vulva in a normal anatomical position with a grossly enlarged clitoris, which contained an os clitoris. On examinations of the genital gland, there were testis, epididymis, ductus deferens and uterus. The histology of both gonads was primarily testis. Seminiferous tubules were divided into many parts by fibrous connective tissue. A small number of spermatogonia was present, but large numbers of Leydig's cells were existed. A normal female karyotype (78, XX) was detected in metaphase spreads obtained from cultured peripheral lymphocytes. Y chromosome specific sequences were not detected in genomic DNA by PCR. After 27 months, the os clitoris was larger than 3-month-old dog and os bone was more calcified than young age. Combining the results of cytogenetic, molecular genetic and histological examinations, the dog was diagnosed as a female hermaphrodite with Sry-negative XX sex reversal.

• 한국임상수의학회지
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• 제32권2호
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• pp.209-211
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• 2015

5살 샴 고양이가 시력 저하를 주증으로 내원하였다. 안검사 상 양안 실명했으며, 동공 빛 반사는 양안 모두 저하되어 있었다. 전안부에는 이상 소견이 없었지만, 안저 검사에서 양안의 반사판 과반사와 망막 혈관 위축이 관찰되었다. 문진 상 점진적인 시력 소실을 보였으며, 신체 검사 상 감염이나 염증을 의심할만한 증거가 확인되지 않았으므로 이에 유전성 망막 변성으로 진단하였다. 이 증례는 한국 샴 고양이 집단에 유전성 망막 변성을 일으키는 유전자가 도입되었을 가능성을 시사하므로 번식에 있어 주의를 요한다.

• 한국임상수의학회지
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• 제32권2호
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• pp.205-208
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• 2015

6년령 중성화 수컷의 말티즈가 서울대학교 부속 동물병원에 내원하였다. 안검사 상 우안의 전방출혈 및 안방수 흐림이 확인되었으며 포도막염에 대한 치료가 진행되었다. 4개월 후 우안 홍채의 등쪽 측면의 전방변위가 확인되었으며 안초음파 검사상 모양체 유래의 종괴로 잠정 진단되었다. 흉부 및 복부 영상검사에서는 종양의 전이소견이 발견되지 않았다. 이후 지속적인 포도막염과 종괴의 종대로 인해 우안의 안구 적출을 실시하였다. 조직병리학적 검사에서 우안의 종괴는 만성적인 출혈을 동반한 전포도막 흑색세포종으로 확진되었다. 본 증례와 같이 안내 종양 환자에서 비수술적인 처치로 눈의 지속적인 출혈이나 염증이 호전되지 않는 경우, 안구적출을 통한 적절한 안내 종양의 제거가 고려되어야 한다.

• 한국임상수의학회지
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• 제33권1호
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• pp.25-29
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• 2016

5-7개월령의 세 마리 말티즈가 전남대학교 동물병원에 IV급 근원심교합으로 내원하였다. 첫 번째 증례의 부정교합은 교정 버튼과 Masel chain을 사용하여 하악 견치를 뒤쪽으로 이동시켜 교정하였다. 두 번째 증례는 교정 버튼과 체인을 이용하여 전방전위된 견치를 교정하였다. 하악 견치가 후방으로 이동이 완료된 후 상악에 finger spring과 함께 arch wire를 적용하여 전치를 앞쪽으로 이동시켰다. 세 번째 증례는 버튼과 체인을 이용하여 하악 견치를 후방으로 이동시킨 후 상악에 finger spring과 함께 arch wire를 적용하여 전치를 앞쪽으로 이동시켰다. 또한 하악 견치에 부착시킨 버튼에 elastic band를 장착하여 하악 전치를 후방으로 이동시켰다. 결과적으로 모든 환자에서 성공적으로 정상적 교합을 재건할 수 있었다.

• 한국치위생학회지
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• 제7권4호
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• pp.595-609
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• 2007

The purpose of this study was to classify the courses of the dental-hygiene curricula into several categories by field, to incorporate the subjects in the same category into an integrated course, and to suggest how to ensure the successful phase-in application of integrative education according to Ronald M. Harden's 11-stage integrative ladder model. The findings of the study were as follows: 1. When the existing curricula were analyzed, it's found that many credits were provided to the courses in the area of basic dentistry that offered both theory and practice. In particular, the subjects tested by the national examination were offered by every college. In the field of public oral health, the largest number of credits was allocated to theory of oral prophylaxis and practice courses. In clinical area, clinical practice, in the area of dental office management, dental insurance course was given the largest credit. There were 31 to 61 major subjects in the colleges, which indicated that the major subjects were segmented in detail. 2. It seemed necessary to incorporate the subjects in the field of basic dentistry into oral biology, and theory of oral prophylaxis/practice, preventive dentistry/practice, preclinical stage, emergency treatment and introduction to dental hygiene should be integrated in to clinical dental hygiene. The courses in clinical area should be combined into clinical dentistry, and in the field of medical management, dental insurance, hospital management and medical relation law should be incorporated into management of dental clinic. 3. In the 11-stage integrative ladder, the subjects in the same field could perfectly be incorporated as the stages advanced. Each of the subjects was less emphasized, and communication and joint plans among teachers who were respectively in charge of the courses were increasingly considered important. Specifically, there should be a consensus among the teachers in regard to the outline of teaching programs, order of education. objects and objectives of programs and what and how to evaluate.