• Title/Summary/Keyword: TdT

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A study on the electron transport coefficients using monte carlo method in argon gas (몬테칼로법을 이용한 Ar기체의 전자수송계수에 관한 연구)

  • 하성철;전병훈
    • Electrical & Electronic Materials
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    • v.8 no.6
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    • pp.685-692
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    • 1995
  • The electron transport coefficients in argon gas is studied over the range of E/N values from 85 to 566 Td by the Monte Carlo method considering the latest cross section data. The result of the Monte Carlo method analysis shows that the value of the electron transport coefficients such as the electron drift velocity, the ratio of the longitudinal and transverse diffusion coefficients to the mobility. It is also found that the electron transport coefficients calculated by the two-term approximation analysis agree well with those by Monte Carlo calculation. The electron energy distributions function were analysed in argon at E/N=283, and 566 Td for a case of the equilibrium region in the mean electron energy. A momentum transfer cross section for the argon atom which was consistent with both of the present electron transport coefficients was derived over the range of mean electron energy from 10.3 to 14.5 eV, also suggested as a set of electron cross section for argon atom. The validity of the results obtained has been confirmed by a Monte Carlo simulation method.

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Exercise-induced beige adipogenesis of iWAT in Cidea reporter mice

  • Kim, Jin Kyung;Go, Hye Sun;Kim, Sol Pin;Kim, Il Yong;Lee, Yun Hee;Oh, Seung Hyun;Lee, Ho;Seong, Je Kyung
    • BMB Reports
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    • v.55 no.4
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    • pp.187-191
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    • 2022
  • Obesity is caused by an imbalance between energy intake and energy expenditure. Exercise is attracting attention as one of the ways to treat obesity. Exercise induces 'beige adipogenesis' in white adipose tissue, increasing total energy expenditure via energy dissipation in the form of heat. Also, beige adipogenesis can be induced by treatment with a beta-adrenergic receptor agonist. We developed a Cidea-dual reporter mouse (Cidea-P2A-Luc2-T2A-tdTomato, Luciferase/tdTomato) model to trace and measure beige adipogenesis in vivo. As a result, both exercise and injection of beta-adrenergic receptor agonist induced beige adipogenesis and was detected through fluorescence and luminescence. We confirmed that exercise and beta-adrenergic receptor agonist induce beige adipogenesis in Cidea-dual reporter mouse, which will be widely used for detecting beige adipogenesis in vivo.

Effects of $K^+$ lon on in vitro RNA Splicing of T4 Phage Thymidylate Synthase Gene

  • Sung, Jung-Suk;Park, In-Kook
    • Journal of Microbiology
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    • v.34 no.1
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    • pp.49-53
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    • 1996
  • The effects of K$^{+}$ ion on the activity of RNA splicing of T4 phage thymidylate synthase gene have been investigated. The splicing activity was stimulated within the range of 5 to 20 mM concentration of KCI. When the concentration of KCI in the splicing reaction was brought to 100 or 200 mM a small amount of the exonl-intron product (1, 4 kb) was formed with large proportion of primary RNA transcript not undergoing splicing. This observation strongly suggests that there may exist come kinds of interferences with transesterification at the first step of splicing. Overall it can be concluded that K$^{+}$ ion exhibits very unique roles in RNA splicing of tdd gene depending on its concentration.ion.

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Factorization of the Jet Mass Distribution in the Small R Limit

  • Idilbi, Ahmad;Kim, Chul
    • Journal of the Korean Physical Society
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    • v.73 no.9
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    • pp.1230-1239
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    • 2018
  • We derive a factorization theorem for the jet mass distribution with a given $p^J_T$ for the inclusive production, where $p^J_T$ is a large jet transverse momentum. Considering the small jet radius limit ($R{\ll}1$), we factorize the scattering cross section into a partonic cross section, the fragmentation function to a jet, and the jet mass distribution function. The decoupled jet mass distributions for quark and gluon jets are well-normalized and scale invariant, and they can be extracted from the ratio of two scattering cross sections such as $d{\sigma}/(dp^J_TdM^2_J)$ and $d{\sigma}/dp^J_T $. When $M_J{\sim}p^J_TR$, the perturbative series expansion for the jet mass distributions works well. As the jet mass becomes small, large logarithms of $M_J/(p^J_TR)$ appear, and they can be systematically resummed through a more refined factorization theorem for the jet mass distribution.

Change of Morphologic Pelvis and Deviation According to Gender, Age -Radiological Pelvimetry- (성별과 나이에 따른 골반 형태 변화와 골반 변위 -방사선영상을 이용한 골반 계측-)

  • Kang, Yeong-Han;Kim, Seon-Chil
    • Journal of radiological science and technology
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    • v.34 no.2
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    • pp.91-96
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    • 2011
  • The purpose of this study was to analyze the change of morphologic pelvis according to age and gender. Pelvis AP(anterior-posterior) projection were taken from 382 individuals (men: 194, women: 188) at the age of twenty and older. We measured four values of pelvis using CR (computed radiological system) including maximum pelvic breadth (MPB), sacral breadth (SB), transverse diameter of pelvic inlet (TD), and distance between femoral heads (DFH). Average (t-test, ANOVA) and Pearson correlation were calculated for comparison. While there was no significant difference of gender in case of MPB, significant differences were observed in SB (men 97.76 mm, women 102.00 mm), TD (men 138.0 mm, women 149.79 mm), and DFH (men 141.94 mm, women 150.39 mm). The DFH values were negatively correlated with the age (men r=-0.280, women r=-0.207). The morphological changes of pelvis were measured high in the men of 50's and in the women of 60's and 70's. The SB, TD and DFH were greater in the women than in the man. As the ages get higher, the deviation of pelvis were gradually increased, which indicates that the morphological changes of pelvis with respect to the age reflects an aging process.

Estimation for application of the Runoff Analysis using TOPMODEL at an ungaged watershed (미계측유역에 대한 TOPMODEL의 적용성 평가)

  • Kang, Sung-Jun;Park, Young-Gi
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.3
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    • pp.1458-1464
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    • 2011
  • This study is on the application of TOPMODEL-topographic based hydrologic model-to the runoff analysis, The test area was the ssang-chi watershed which is mountainous catchment located in the upstream of the sumjin-gang basin and the watershed area is $126.7km^2$. The six's hourly runoff and precipitation data was selected in the 2006 ~ 2009 year. And the model parameters are calibrated using observed runoff data by Pattern Search method. The topographic index of the ssang-chi catchment was produced by digital elevation model(DEM) of 100m grid. As a results of the analysis, the parameters of model, a decay facter(m), transmissivity(T0), and the unsaturated zone delay(TD) are sensible to hydrologic response, and the simulated runoff data are in good agreement with observed runoff data.

N-Region Addition in Immunoglobulin Kappa Light Chains in B Cell Subsets in Rheumatoid Arthritis: Evidence for Over-expression of TDT in B Lineage

  • Lee, Choong Won;Bridges, S. Louis Jr
    • IMMUNE NETWORK
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    • v.3 no.2
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    • pp.89-95
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    • 2003
  • Background: Unusually high amounts of N region addition and CDR3 length diversity were found in immunoglobulin (Ig) light chain Vk and Jk joins in patients with rheumatoid arthritis (RA). We sought to determine whether this finding is due to excessive activity of the enzyme responsible for N region addition (terminal deoxynucleotidyl transferase [TdT]) in B lineage cells in bone marrow or from positive antigenic selection of B cells with long CDR3 lengths. Methods: We used FACS to isolate $IgM^+/IgD^+$ B cells (predominantly naive) and $IgM^-/IgD^-$ B cells (predominantly class-switched) B cells from peripheral blood of a patient with RA known to have enrichment for long Vk CDR3s and from that of two normal controls. RT-PCR of VkIII transcripts was performed, followed by sequencing of individual cDNA clones. We analyzed the CDR3 lengths and N region additions in 97 clones. Results: There was enrichment for long CDR3 lengths (11 or 12 amino acids) in both $IgM^+/IgD^+$ and $IgM^-/IgD^-$ B cells in RA compared to B cell subsets in the normal controls. The $IgM^+/IgD^+$ B cell subset in RA was markedly enriched for N region addition and was similar to that seen in the $IgM^-/IgD^-$ subset. Conclusion: These data suggest that enrichment for N region addition and long CDR3 lengths in RA may result from unusually high or prolonged activity of TdT in bone marrow.

Sintering of a Mixture of $UO_2$ and $Gd_2 O_3$ Powders Doped With $Cr_2 O_3-SiO_2$

  • Kim, Keon-Sik;Song, Kun-Woo;Kang, Ki-Won;Yang, Jae-Ho;Kim, Jong-Hun
    • Nuclear Engineering and Technology
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    • v.33 no.4
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    • pp.386-396
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    • 2001
  • Mixtures Of AUC-UO$_2$and Gd$_2$O$_3$ Powders doped With Cr$_2$O$_3$ or Cr$_2$O$_3$-SiO$_2$ were Pressed and sintered at 1730 t in hydrogen gas witk various water-vapor contents. The density of UO$_2$- 6wt% Gd$_2$O$_3$ pellets can be increased from 91% TD to 94.5% TD in 1 vol% $H_2O$-H$_2$ gases by the addition of 0.02wt% Cr$_2$O$_3$-(0.01~0.04) wt% SiO$_2$. The magnitude of density increase is much larger in (1~3 vol%) $H_2O$-H$_2$ gases than in 0.05 vol% $H_2O$-H$_2$ gas. The densification of U0$_2$- Gd$_2$O$_3$ compact is significantly delayed in the temperature range between 1300 and 1500 t , but that of compacts with Cr$_2$O$_3$-SiO$_2$ is not. The role of Cr$_2$O$_3$ and SiO$_2$ in densification is discussed.

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A STUDY ABOUT THE APOPTOSIS OF EPITHELIAL CELLS IN THE FUSING FETAL RAT PALATE (흰쥐 태아 구개융합부위 상피세포의 아포프토시스에 관한 연구)

  • Lee, Hong-Joo;Cha, Kyung-Suk;Lee, Jin-Woo
    • The korean journal of orthodontics
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    • v.31 no.1 s.84
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    • pp.71-83
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    • 2001
  • The purpose of this study was to Prove that the medial edge epithelial cells covering the secondary palatal shelves were removed by apoptosis during palatal fusion. 12 mature female rats (Suprague-Dawley) were mated overnight with male rats and sacrificed on days 15.0, 16.5, 16.75, 17.0 of pregnancy. The embryos were removed from the uterus and the heads were embedded in paraffin. The paraffin blocks were sectioned and the sections were undergone H-E staining for general histologic feature and TdT staining for detection of apoptotic cells. The obtained results were as follows. k. In the section of 16.0 and 16.5 day embryos, the palatal shelves were prior to contact and no apoptotic cells wereobserved in the medial edge epithelium. At the initial contact of Palatal shelves, there was a few apoptotic cells in the fusing epithelium. 2. In the 16.75 day embryos, the samples that epithelial seams did not lost there continuity, apoptotic cells were rarely seen at the midline epithelial seam. In contrast, a lot of apoptotic cells were observed at epithelial triangles and the junction between palatal shelves and nasal septum. 3. In the 16,75 day embryos, the samples that epithelial seams lost their continuity and disrupted to epithelial islands, large number, of apoptotic cells were observed at epithelial islands and epithelial triangles. Some apoptotic cells were also observed at the oral, nasal epithelium near the midline. 4. In the 17.0 day embryos, most of epithelial islands were disappeared and mesenchymal confluence was achieved. Apoptotic cells were rarely observed in the mesenchymal tissue which replaced epithelial islands, but there were some apoptotic cells at the epithelial triangles, oral and nasal epithelium. From the results of the study, it was revealed that medial edge epithelial cells of fusing palate were removed by apoptosis. Apoptotic cells were found mainly in the disappearing midline epithelial seam and the oral and nasal epithelial triangles at some late stages of palatal fusion.

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Temperature Profile Analysis of $Ti5_Si_3$ in Self-Propagating High Temperature Synthesis (SHS 법에 의한 $Ti5_Si_3$의 합성시 온도 Profile 분석)

  • 김도경;이형직;김익진;이형복
    • Journal of the Korean Ceramic Society
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    • v.32 no.3
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    • pp.341-348
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    • 1995
  • An analysis of the use of temperature profiles in the determination of the kinetic parameters of combustion synthesis of Ti5Si3 were investigated. From profile analysis, an apparent activation energy of 12KJ/mol was calculated. The Maximum heating rate achieved during 10wt% Ti5Si3 reaction by the product dilution method was approximately $1.5\times$104 K/s. Coupling this value with the measured wave velocity of 7.02 cm/s yields a maximum thermal gradient of 2.14$\times$103 K/cm. The value of tr (=t*) was calculated to be 1.2$\times$10-1 s and the value of td (=tx) was calculated to be 32.89 s. Using the definition of t* and the measured wave velocity, the effective thermal diffusivity, $\alpha$, was calculated to be 0.59$\times$10 $\textrm{cm}^2$/s. From these analysis, the power function, G, was also calculated.

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