• 제목/요약/키워드: Target History

검색결과 370건 처리시간 0.028초

Complete mitochondrial genome of the Japanese oak silkmoth, Antheraea yamamai (Lepidoptera: Saturniidae), from Jeju Island, Korea

  • Kim, Kee-Young;Park, Jeong Sun;Lee, Keon Hee;Kim, Min Jee;Kim, Seong-Wan;Park, Jong-Woo;Kang, Sang-Kuk;Kim, Nam-Suk;Kim, Iksoo
    • International Journal of Industrial Entomology and Biomaterials
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    • 제44권2호
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    • pp.65-71
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    • 2022
  • The wild silkmoth Antheraea yamamai Guérin-Méneville, 1861 (Lepidoptera: Saturniidae) is an important producer of silk that is superior to the silk produced by traditional domesticated silkworm. In this study, we sequenced the complete mitochondrial genome (mitogenome) of An. yamamai collected from Jeju Island, which is the southernmost island approximately 100 km offshore southward from the Korean Peninsula. Determining this sequence will be necessary for tracing the biogeographic history of the species and developing molecular markers for identifying the origin of commercial products. Comparison of the sequence divergence among two available and the current mitogenomes revealed a low but substantial number of substitutions, totaling 23 nucleotides in the whole genome. CytB and ND5 showed the highest variability with five and four variations, respectively, suggesting that these regions will be prior regions to target for subsequent biogeographic and diagnosis study. Phylogenetic reconstruction based on all available sequences of Saturniidae showed that An. yamamai is a sister to the congeneric species An. pernyi, corroborating that Antheraea is a highly supported monophyletic group. The tribe Saturniini was clearly non-monophyletic and interrupted by Attacini and Bunaeini.

Seismic vulnerability assessment of existing private RC constructions in northern Algeria

  • Belhamdi, Nourredine;Kibboua, Abderrahmane;Tahakourt, Abdelkader
    • Earthquakes and Structures
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    • 제22권1호
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    • pp.25-38
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    • 2022
  • The RC private constructions represent a large part of the housing stock in the north part of Algeria. For various reasons, they are mostly built without any seismic considerations and their seismic vulnerability remains unknown for different levels of seismic intensity possible in the region. To support future seismic risk mitigation efforts in northern Algeria, this document assesses the seismic vulnerability of typical private RC constructions built after the Boumerdes earthquake (May 21, 2003) without considering existing seismic regulation, through the development of analytical fragility curves. The fragility curves are developed for four representative RC frames in terms of slight, moderate, extensive, and complete damage states suggested in HAZUS-MH 2.1, using nonlinear time history analyses. The numerical simulation of the nonlinear seismic response of the structures is performed using the SeismoStruct software. An original intensity measure (IM) is proposed and used in this study. It is the zone acceleration coefficient "A", through which the seismic hazard level is represented in the Algerian Seismic Regulations. The efficiency, practicality, and proficiency of the choice of IM are demonstrated. Incremental dynamic analyses are conducted under fifteen ground motion accelerograms compatible with the elastic target spectrum of the Algerian Seismic Regulations. In order to cover all the seismic zones of northern Algeria, the accelerograms are scaled from 0.1 to 2.5 in increments of 0.1. The results mainly indicate that private constructions built after the Boumerdes earthquake in the moderate and high seismic zones with four (04) or more storeys are highly vulnerable.

COVID-19 중의 진료지침에 수록된 예방 처방 분석 (Analysis of Preventive Formulas Included in Guidelines for Traditional Chinese Medical Treatment of COVID-19)

  • 김상현;신상원;김종현
    • 대한예방한의학회지
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    • 제27권1호
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    • pp.69-87
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    • 2023
  • Objectives : This study collected and analyzed information related to preventive formulas from continuously published and revised COVID-19 treatment guidelines in various regions of China. Methods : We collected treatment guidelines published in different regions of China and categorized formulas for prevention and medical observation period listed in them according to the editions. The categorized preventive formulas were compared by type and target group. Results : Herbal medicines used for prevention included formulas derived from Korean medical classics, such as Okbyeongpungsan(玉屏風散) and Eunkyosan(銀翹散). The newly composed formulas, totaling over 100, were created by adding, subtracting, and combining formulas such as Sang-gukeum(桑菊飮), Eunkyosan(銀翹散), Sasammaekmundongtang(沙參麥門冬湯), Okbyeongpungsan(玉屏風散), Gwakhyangjeong-gisan(藿香正氣散), and Soshihotang(小柴胡湯). Patent medicines including Huoxiangzhengqi capsule(藿香正氣膠囊), Lianhuaqingwen capsule(連花淸瘟膠囊), Shufengjiedu capsule(疏風解毒膠囊), and Jinhuaqinggan granule(金花淸感顆粒) were frequently used, mainly targeting close contacts. These medicines were used differently depending on the specific population group, such as the general population, the elderly, children, pregnant women, and patients with underlying diseases, and were also applied differently according to the individual's constitution. Conclusion : We were able to identify various background factors contained in the guidelines for the use of preventive formulas presented by TCM group, and understand the social conditions that enabled the group to provide such guidelines. Through this, thorough preparation should be made so that the Korean Medicine can actively respond to another future pandemic.

Comparative Genomic Analysis and Rapid Molecular Detection of Xanthomonas euvesicatoria Using Unique ATP-Dependent DNA Helicase recQ, hrpB1, and hrpB2 Genes Isolated from Physalis pubescens in China

  • Faisal Siddique;Yang Mingxiu;Xu Xiaofeng;Ni Zhe;Haseeb Younis;Peng Lili;Zhang Junhua
    • The Plant Pathology Journal
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    • 제39권2호
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    • pp.191-206
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    • 2023
  • Ground cherry (Physalis pubescens) is the most prominent species in the Solanaceae family due to its nutritional content, and prospective health advantages. It is grown all over the world, but notably in northern China. In 2019 firstly bacterial leaf spot (BLS) disease was identified on P. pubescens in China that caused by both BLS pathogens Xanthomonas euvesicatoria pv. euvesicatoria resulted in substantial monetary losses. Here, we compared whole genome sequences of X. euvesicatoria to other Xanthomonas species that caused BLS diseases for high similarities and dissimilarities in genomic sequences through average nucleotide identity (ANI) and BLAST comparison. Molecular techniques and phylogenetic trees were adopted to detect X. euvesicatoria on P. pubescens using recQ, hrpB1, and hrpB2 genes for efficient and precise identification. For rapid molecular detection of X. euvesicatoria, loop-mediated isothermal amplification, polymerase chain reaction (PCR), and real-time PCR techniques were used. Whole genome comparison results showed that the genome of X. euvesicatoria was more closely relative to X. perforans than X. vesicatoria, and X. gardneri with 98%, 84%, and 86% ANI, respectively. All infected leaves of P. pubescens found positive amplification, and negative controls did not show amplification. The findings of evolutionary history revealed that isolated strains XeC10RQ, XeH9RQ, XeA10RQ, and XeB10RQ that originated from China were closely relative and highly homologous to the X. euvesicatoria. This research provides information to researchers on genomic variation in BLS pathogens, and further molecular evolution and identification of X. euvesicatoria using the unique target recQ gene through advance molecular approaches.

A Pilot Study Exploring Temporal Development of Gut Microbiome/Metabolome in Breastfed Neonates during the First Week of Life

  • Imad Awan;Emily Schultz;John D. Sterrett;Lamya'a M. Dawud;Lyanna R. Kessler;Deborah Schoch;Christopher A. Lowry;Lori Feldman-Winter;Sangita Phadtare
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • 제26권2호
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    • pp.99-115
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    • 2023
  • Purpose: Exclusive breastfeeding promotes gut microbial compositions associated with lower rates of metabolic and autoimmune diseases. Its cessation is implicated in increased microbiome-metabolome discordance, suggesting a vulnerability to dietary changes. Formula supplementation is common within our low-income, ethnic-minority community. We studied exclusively breastfed (EBF) neonates' early microbiome-metabolome coupling in efforts to build foundational knowledge needed to target this inequality. Methods: Maternal surveys and stool samples from seven EBF neonates at first transitional stool (0-24 hours), discharge (30-48 hours), and at first appointment (days 3-5) were collected. Survey included demographics, feeding method, medications, medical history and tobacco and alcohol use. Stool samples were processed for 16S rRNA gene sequencing and lipid analysis by gas chromatography-mass spectrometry. Alpha and beta diversity analyses and Procrustes randomization for associations were carried out. Results: Firmicutes, Proteobacteria, Bacteroidetes and Actinobacteria were the most abundant taxa. Variation in microbiome composition was greater between individuals than within (p=0.001). Palmitic, oleic, stearic, and linoleic acids were the most abundant lipids. Variation in lipid composition was greater between individuals than within (p=0.040). Multivariate composition of the metabolome, but not microbiome, correlated with time (p=0.030). Total lipids, saturated lipids, and unsaturated lipids concentrations increased over time (p=0.012, p=0.008, p=0.023). Alpha diversity did not correlate with time (p=0.403). Microbiome composition was not associated with each samples' metabolome (p=0.450). Conclusion: Neonate gut microbiomes were unique to each neonate; respective metabolome profiles demonstrated generalizable temporal developments. The overall variability suggests potential interplay between influences including maternal breastmilk composition, amount consumed and living environment.

중국 가정교육지도 서비스에 관한 문헌고찰 (A Literature Review on the Development of the Family Education Guidance Service in China)

  • 모효설;진미정
    • Human Ecology Research
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    • 제61권3호
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    • pp.415-427
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    • 2023
  • The Family Education Guidance Service is a public service developed by the government to give guidance and service to parents on educating their children in China. Recently, the service has attracted increasing attention from scholars, as well as from the Chinese Government. To assess the current status of research on the Family Education Guidance Service, this paper firstly introduces the policy history and clarifies the definition of the Family Education Guidance Service and other relevant terms used in China. It then presents a review of studies on the Family Education Guidance Service published in journals with high-grade ratings and analyzes the characteristics of current research in terms of year of publication, author affiliations, research themes, research methods, and target groups. Based on these, it makes suggestions for future development. Overall, 43 papers are reviewed, the findings of which reveal that related research is at the beginning of an upswing. Most authors belong to education colleges and law colleges of universities. The themes studied most often are the strategy exploration and legal construction of the Family Education Guidance Service. The parents of primary- and middle-school students are the most commonly studied group, followed by schoolteachers. The results indicate that despite the growing number of publications, research in this field is still in its early stages and many aspects require further exploration.

시계열 예측 모델을 활용한 암호화폐 투자 전략 개발 (Developing Cryptocurrency Trading Strategies with Time Series Forecasting Model)

  • 김현선;안재준
    • 산업경영시스템학회지
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    • 제46권4호
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    • pp.152-159
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    • 2023
  • This study endeavors to enrich investment prospects in cryptocurrency by establishing a rationale for investment decisions. The primary objective involves evaluating the predictability of four prominent cryptocurrencies - Bitcoin, Ethereum, Litecoin, and EOS - and scrutinizing the efficacy of trading strategies developed based on the prediction model. To identify the most effective prediction model for each cryptocurrency annually, we employed three methodologies - AutoRegressive Integrated Moving Average (ARIMA), Long Short-Term Memory (LSTM), and Prophet - representing traditional statistics and artificial intelligence. These methods were applied across diverse periods and time intervals. The result suggested that Prophet trained on the previous 28 days' price history at 15-minute intervals generally yielded the highest performance. The results were validated through a random selection of 100 days (20 target dates per year) spanning from January 1st, 2018, to December 31st, 2022. The trading strategies were formulated based on the optimal-performing prediction model, grounded in the simple principle of assigning greater weight to more predictable assets. When the forecasting model indicates an upward trend, it is recommended to acquire the cryptocurrency with the investment amount determined by its performance. Experimental results consistently demonstrated that the proposed trading strategy yields higher returns compared to an equal portfolio employing a buy-and-hold strategy. The cryptocurrency trading model introduced in this paper carries two significant implications. Firstly, it facilitates the evolution of cryptocurrencies from speculative assets to investment instruments. Secondly, it plays a crucial role in advancing deep learning-based investment strategies by providing sound evidence for portfolio allocation. This addresses the black box issue, a notable weakness in deep learning, offering increased transparency to the model.

Optimization of base-isolated structure with negative stiffness tuned inerter damper targeting seismic response reduction

  • Jean Paul Irakoze;Shujin Li;Wuchuan Pu;Patrice Nyangi;Amedee Sibomana
    • Earthquakes and Structures
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    • 제25권6호
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    • pp.399-415
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    • 2023
  • In this study, we investigate the use of a negative stiffness tuned inerter damper system to improve the performance of a base-isolated structure. The negative stiffness tuned inerter damper system consists of a tuned inerter damper connected in parallel with a negative stiffness element. To find the optimal parameters for the base-isolated structure with negative stiffness tuned inerter damper system, we develop an optimization method based on performance criteria. The objective of the optimization is to minimize the superstructure acceleration response ratio, while ensuring that the base displacement response ratio remains below a specified target value. We evaluate the proposed method by conducting numerical analyses on an eight-story building. The structure is modeled using both a simplified 3-degree-of-freedom system and a more detailed story-by-story shear-beam model. Lastly, a comparative analysis using time history analysis is performed to compare the performance of the base-isolated structure with negative stiffness tuned inerter damper system with that of the base-isolated structure and base-isolated structure with tuned inerter damper systems. The results obtained from the comparative analysis show that the negative stiffness tuned inerter damper system outperforms the tuned inerter damper system in reducing the dynamic seismic response of the base-isolated structure. Overall, this study demonstrates that the negative stiffness tuned inerter damper system can effectively enhance the performance of base-isolated structures, providing improved seismic response reduction compared to other systems.

플로지스톤설에서 산소설로의 개념 변화 과정에서 변칙 사례와 대안 가설에 대한 과학자들과 학생들의 반응 비교 (A Comparison of Scientists' and Students' Responses to Discrepant Event and Alternative Hypothesis in the Conceptual Change Processes from the Phlogiston Theory to the Oxygen Theory)

  • 노태희;윤정현;강훈식;강석진
    • 한국과학교육학회지
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    • 제26권7호
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    • pp.798-804
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    • 2006
  • 이 연구에서는 플로지스톤설에서 산소설로의 개념변화 과정에서 제시된 변칙 사례와 대안 가설에 대한 학생들의 반응을 조사하고, 이를 과학자들의 반응과 비교했다. 변칙 사례와 대안 가설에 대한 과학자들의 반응은 과학사 관련 문헌에서 수집했다. 선개념 검사를 실시하여 연소에 대한 목표 오개념을 지닌 중학교 2학년 학생 148명을 선발했다. 학생들에게 변칙 사례와 대안 가설을 제시하고, 이에 대한 학생들의 반응을 조사했다. 연구 결과, 과학자들과 학생들에게서 유사한 반응 유형이 나타났지만, 동시에 명확한 차이점도 있었다. 과학자들은 변칙 사례의 문제점을 밝히고자 노력하는 경향이 있었지만, 학생들은 자신들의 초기이론에 대한 신념을 고수하기 위해 변칙 사례를 거부하거나 배제하는 경향이 있었다. 또한, 대안 가설을 접한 후에 자신의 신념을 바꾸는 학생은 일부에 불과했다.

비선형동적해석을 통한 건식 기계적이음을 갖는 프리캐스트 모멘트 골조의 동등성 평가 (Evaluation of Emulative Level for Precast Moment Frame Systems with Dry Mechanical Splices by Using Nonlinear Dynamic Analysis)

  • 김선훈;이원준;이득행
    • 한국지진공학회논문집
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    • 제28권2호
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    • pp.85-92
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    • 2024
  • This study presents code-compliant seismic details by addressing dry mechanical splices for precast concrete (PC) beam-column connections in the ACI 318-19 code. To this end, critical observations of previous test results on precast beam-column connection specimens with the proposed seismic detail are briefly reported in this study, along with a typical reinforced concrete (RC) monolithic connection. On this basis, nonlinear dynamic models were developed to verify seismic responses of the PC emulative moment-resisting frame systems. As the current design code allows only the emulative design approach, this study aims at identifying the seismic performances of PC moment frame systems depending on their emulative levels, for which two extreme cases were intentionally chosen as the non-emulative (unbonded self-centering with marginal energy dissipation) and fully-emulative connection details. Their corresponding hysteresis models were set by using commercial finite element analysis software. According to the current seismic design provisions, a typical five-story building was designed as a target PC building. Subsequently, nonlinear dynamic time history analyses were performed with seven ground motions to investigate the impact of emulation level or hysteresis models (i.e., energy dissipation performance) on system responses between the emulative and non-emulative PC moment frames. The analytical results showed that both the base shear and story drift ratio were substantially reduced in the emulative system compared to that of the non-emulative one, and it indicates the importance of the code-compliant (i.e., emulative) connection details on the seismic performance of the precast building.