• 제목/요약/키워드: Taraxerone

검색결과 5건 처리시간 0.014초

A pentacyclic triterpenoid possessing analgesic and anti-inflammatory activities from the fruits of Dregea volubilis

  • Biswas, M.;Biswas, K.;Ghosh, A.K.;Haldar, P.K.
    • Advances in Traditional Medicine
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    • 제9권4호
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    • pp.315-319
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    • 2009
  • In present study evaluate the analgesic and anti-inflammatory activity of the compound obtained from the petroleum ether (40 - 60$^{\circ}C$) extract of the fruits from Dregea volubilis in Swiss albino mice and in Wister albino rats respectively. Dried and crushed fruits of Dregea volubilis were extracted by petroleum ether (40 - 60$^{\circ}C$), the proper solvent system was developed by TLC and subjected to column chromatography for obtaining the pure compound/s. IR, MASS, NMR (PMR, C13 NMR and DEPT) spectroscopic analysis were done to elucidate the structure of the compound/s. The petroleum ether (40 - 60$^{\circ}C$) extract of the fruits of Dregea volubilis led to isolation of a pentacyclic triterpenoid designated as taraxerone and characterized as D- friedoolean- 14- en, 3 one. Taraxerone had been screened for analgesic activity in Swiss albino mice and anti-inflammatory activity in Wister albino rats at the dose of 5 mg/kg body weight orally and exhibit significant analgesic and anti-inflammatory properties.

Fatty Acids and Phytochemical Components of Ipomoea spp. Seeds

  • Das, Saubhik;Ganguly, Subhendu Narayan;Mukherjee, Kalyan Kumar
    • Natural Product Sciences
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    • 제5권3호
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    • pp.121-123
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    • 1999
  • Twelve species of Ipomoea were investigated for allelopathic behavior. Seed extracts of I. quamoclit, I. nil and I. pes-tigridis showed significant allelopathy over germination of other seeds. Investigation on seed extracts of I. quamoclit, revealed the presence of several phytochemical components viz., n-triacontanol, sitosterol, stigmasterol, ${\alpha}-amyrin$, taraxerone, taraxerol, erythrodiol, cucurbitacin-G. Seed fat of twelve species were also analyzed.

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Pentacyclic Triterpenoids from Mallotus apelta

  • Kiem, Phan-Van;Minh, Chau-Van;Huong, Hoang-Thanh;Nam, Nguyen-Hoai;Lee, Jung-Joon;Kim, Young-Ho
    • Archives of Pharmacal Research
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    • 제27권11호
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    • pp.1109-1113
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    • 2004
  • A new triterpene (1) and six known pentacyclic terpenoids (2-7) were isolated from the methanol extract of the dried leaves from Mallotus apelta. Based on the spectral and chemical evidence, their structures were determined to be 3$\alpha$-hydroxyhop-22(29)-ene (1), hennadiol (2), friedelin (3), friedelanol (4), epifriedelanol (5), taraxerone (6), and epitaraxerol (7).

오령지 저극성 분획으로부터의 화합물 분리 (Compounds from Non-polar Fraction of the Feces of Trogopterus xanthipes)

  • 김유나;심상희
    • 생약학회지
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    • 제46권1호
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    • pp.31-37
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    • 2015
  • Thirteen compounds were isolated from n-hexane layer of the extracts of feces of Trogopterus xanthipes. Their chemical structures were elucidated as lupeol (1), lupenone (2), simiarenol (3), epitaraxerol (4), taraxerone (5), fatty acid esters of 11-oxo-${\beta}$-amyrin (6), 12-oleane-3,11-dione (7), $5{\beta}$-stigmastan-$3{\alpha}$-ol (8), $5{\beta}$-stigmastan-$3{\beta}$-ol (9), $5{\alpha}$-stigmastan-3-one (10), $5{\beta}$-stigmastan-3-one (11), $5{\beta}$-cholestan-$3{\alpha}$-ol (12), and 2-methoxyphenanthrene (13) on the basis of spectroscopic data. Even though all the isolated compounds are known, to the best of our knowledge, all the compounds (1-13) are reported from this species for the first time.