• The Journal of Korean Medicine
• /
• v.25 no.2
• /
• pp.87-97
• /
• 2004

Objectives : To identify the effect of Taeyeumjowee-tang on the treatment of obesity Methods : After having been fed a high-fat diet for 6 weeks, obese white rats were classified into three groups. Control group 1 was fed a high-fat diet for 2 more weeks. Control group 2 was fed a normal diet for 2 weeks. The Sample group was fed Taeyeumjowee-tang extract with a normal diet for 2 weeks. The result of the comparison among the three groups was as follows. Results : The Sample group decreased significantly as compared with the Control 1 and 2 groups in changes of the body weight, fat cell size, fat accumulation, insulin, triglyceride, total cholesterol, total lipid, free fatty acid and UCP1. Conclusions : Taeyeumjowee-tang has significant effect on the treatment of obesity resulting from a high-fat diet. Especially, it was a sure remedy for Control group 2 that was fed normal1y after having a high-fat diet.

• Journal of Korean Medicine for Obesity Research
• /
• v.1 no.1
• /
• pp.77-83
• /
• 2001

We wanted to study the effect of Taeyeumjowee-tang and electroacupunctre combined-therapy on obese patients. From 1 March, 2000 to 30, September, 2000 we studied 33 out-ward patients who clinically diagnosed obesity and classified Tae-Em-In by QSCC(Questionnaire of Sasang Constitution Classification). We treated the patients by electroacupuncture therapy and taeyeumjowee-tang for 6 weeks, We investigated the change of mean body weight, mean body mass index, mean obesity degree, percent body fat and waist-hip circumference ratio. To analyze the results we used repeat measure method by SPSS ver 7.5. The results were as follows: 1. From $70.4{\pm}11.4\;to\;64.9{\pm}8.7$, mean body weight was significantly decreased according to combined-therapy. 2. From $27.2{\pm}3.2\;to\;24.6{\pm}2.7$, mean BMI was significantly decreased according to combined-therapy. 3. From $116.7{\pm}13.9\;to\;104.4{\pm}12.1$, mean obesity degree was significantly decreased according to combined-therapy. 4. From $32.1{\pm}6.8\;to\;27.4{\pm}7.5$, percent body fat was significantly decreased according to combined-therapy. 5. From $0.90{\pm}0.06\;to\;$0.86{\pm}0.06$, waist-hip circumference ratio was significantly decreased according to combined-therapy. In this study we knew the combined-therapy of electroacupuncture and taeyeumjowee-tang is very efficient in obese patient.

• Journal of Oriental Neuropsychiatry
• /
• v.18 no.2
• /
• pp.57-74
• /
• 2007

Objective : The purpose of this study was to investigate the anti-obesity and anti-hyperlipidemic Effects of Taeyeumjowee-tang and its modified prescription on the animal model of obesity and hyperlipidemia induced high-fat diet. Method : 1) The extracts of Taeyeumjowee-tang (TJT) and its modified prescription, Taeyeumjoweetang gagam-bang (TJGB) were evaluated for its inhibitory effects on obesity. 2) The body weight and feed weight were determined in the pre-treated and post-treated mice and the lipid profiles in the serum were analyzed in order to evaluate the anti-hyperlipidemia action of the extracts. 3) The effect of each extract was investigated for the influences on monoamine oxidase activity and HMG-CoA reductase activity. Results 1. TJT and TJGB extracts dose-dependently reduced the body weight and feed intake in normal mice. The effect of TJGB extract was better than that of TJT extract. 2. TJGB extract diminished the body weight increase and reduced the feed intake in the pre-treatment or post-treatment of the extract 3. TJGB extract decreased the amount of total cholesterol slightly and triglyceride potently after the pre-treatment or post-treatment, but HDL cholesterol exhibited no remarkable change compared with control. 4. TJGB extract weakly potentiated the monoamine oxidase activity, but its effect was better than that of TJT extract. 5. TJGB extract weakly inhibited the HMG-CoA reductase activity, but its effect was better than that of TJT extract. Conclusion : Taeyeumjowee-tang and its modified prescription can clinically be useful as anti-obesity drug and also for the improvement of hyperlipidemia.

• Journal of Sasang Constitutional Medicine
• /
• v.21 no.1
• /
• pp.237-246
• /
• 2009

1. Objectives To compare the contents of heavy metals, residual pesticides and sulfur dioxide before/after decoction. 2. Methods The heavy metal contents before/after decoction were measured by Inductively Coupled Plasma Atomic Emission Spectrometry (ICP-AES) and mercury analyzer. In order to analyze pesticides in 3 samples we used simultaneous multi-residue analysis of pesticides by GC/ECD, followed by GC/MSD analysis to confirm the identity of the detected pesticide in each sample. In addition, the contents of sulfur dioxide (SO2) were performed by Monier-Williams distillation method. 3. Results 1) The mean values of heavy metal contents (mg/kg) for the samples were as follows: Yuldahanso-tang (before decoction - Pb; 1.85, Cd; 0.148, As; 0.042 and Hg; 0.003, after decoction - Pb; 0.096, Cd; 0.006, As; 0.006 and Hg; 0.002), Chongsimyonja-tang (before decoction - Pb; 1.193, Cd; 0.094, As; 0.084 and Hg; 0.008, after decoction - Pb; 0.053, Cd; 0.007, As; 0.011 and Hg; not detected) and Taeyeumjowee-tang (before decoction - Pb; 0.878, Cd; 0.078, As; 0.302 and Hg; 0.004, after decoction - Pb; 0.079, Cd; 0.005, As; 0.006 and Hg; not dectcted). 2) Contents (mg/kg) of residual pesticides before/after decoction in all samples were not detected. 3) Contents (mg/kg) of sulfur dioxide (SO2) before decoction in Yuldahanso-tang, Chongsimyonja-tang and Taeyeumjowee-tang exhibited 6.1, 37.8, 31.5 and 19.7, respectively. However, contents of sulfur dioxide after decoction in all samples were not detected. 4. Conclusion These results will be used to establish a criterion of heavy metals, residual pesticides and sulfur dioxide.

• The Korea Journal of Herbology
• /
• v.25 no.3
• /
• pp.103-109
• /
• 2010

Objective : The aim of this study is to investigate the effects of Taeyeumjoweetang (TJT) and Taeyeumjoweebaemahwangtang (TJBM) medication on body weight change and serum total cholesterol, HDL cholesterol, LDL cholesterol, triglyceride, free fatty acid, total lipid, phospholipid level, and CBC of obese rats. Methods : Obese rats induced by high-fat fed are medicated for 7 weeks. 32 rats are divided into four groups depending on the medication; normal group (general-fat fed and no-medication), control group (high-fat fed and no medication), TJT group (high-fat fed and TJT medication) and TJBM group (high-fat fed and TJBM medication). After 7 weeks, obesity related index and CBC are analysed. Results : There is a significant statistical difference between control group and TJBM group for the body weight change, the total cholesterol, HDL cholesterol, and triglyceride level: total cholesterol values of control and TJBM are $59.25{\pm}9.56 mg/d{\ell}$ and $39.13{\pm}9.08 mg/d{\ell}$, respectively; HDL cholesterol values of control and TJBM are $22.0{\pm}1.69 mg/d{\ell}$ and $13.75{\pm}2.19 mg/d{\ell}$, respectively; triglyceride values of control and TJBM are $12.75{\pm}3.37 mg/d{\ell}$ and TJBM : $8.13{\pm}1.64 mg/d{\ell}$, respectively. There is a significant statistical difference between control group, TJT, and TJBM group for free fatty acid and phospholipid level: free fatty acid values of control, TJT, and TJBM are $936.25{\pm}89.59 {\mu}m/{\ell}$, $738.75{\pm}109.47{\mu}m/{\ell}$, and $720{pm}150.71{\mu}m/{\ell}$, respectively; phospholipid values of Control, TJT, and TJBM are $87.13{\pm}11.86mg/d{\ell}$, $70.5{\pm}12.22 mg/d{\ell}$, and $60.5{\pm}11.1 mg/d{\ell}$, respectively. Conclusion : These results suggest that medication of TJT and TJBM is effective for the treatment of obesity. Especially, TJBM is more effective than TJT.